scholarly article | Q13442814 |
P2093 | author name string | A W Segal | |
F B Wientjes | |||
J J Hsuan | |||
N F Totty | |||
P2860 | cites work | Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation | Q29616396 |
Progressive sequence alignment as a prerequisite to correct phylogenetic trees | Q29618216 | ||
SH3--an abundant protein domain in search of a function | Q30195311 | ||
The superoxide-generating oxidase of phagocytic cells. Physiological, molecular and pathological aspects | Q34507357 | ||
Neutrophil nicotinamide adenine dinucleotide phosphate oxidase assembly. Translocation of p47-phox and p67-phox requires interaction between p47-phox and cytochrome b558. | Q40339903 | ||
The biochemical basis of the NADPH oxidase of phagocytes. | Q40904508 | ||
Cytochrome b-245 is a flavocytochrome containing FAD and the NADPH-binding site of the microbicidal oxidase of phagocytes | Q41619617 | ||
Localization of the 47 kDa phosphoprotein involved in the respiratory-burst NADPH oxidase of phagocytic cells | Q41817828 | ||
Two forms of autosomal chronic granulomatous disease lack distinct neutrophil cytosol factors. | Q42001699 | ||
Phosphorylation of the subunits of cytochrome b-245 upon triggering of the respiratory burst of human neutrophils and macrophages | Q42088807 | ||
Accelerated high‐sensitivity microsequencing of proteins and peptides using a miniature reaction cartridge | Q42842110 | ||
The cytosolic components of the respiratory burst oxidase exist as a M(r) approximately 240,000 complex that acquires a membrane-binding site during activation of the oxidase in a cell-free system | Q43680605 | ||
Stimulated neutrophils from patients with autosomal recessive chronic granulomatous disease fail to phosphorylate a Mr-44,000 protein | Q43689162 | ||
Purification of the 260 kDa cytosolic complex involved in the superoxide production of guinea pig neutrophils | Q46981093 | ||
Signal transduction. How receptors turn Ras on. | Q55066288 | ||
Activation of the NADPH oxidase involves the small GTP-binding protein p21rac1 | Q59053220 | ||
Absence of cytochrome b reduction in stimulated neutrophils from both female and male patients with chronic granulomatous disease | Q59512522 | ||
Reconstitution of neutrophil NADPH oxidase activity in the cell-free system by four components: p67-phox, p47-phox, p21rac1, and cytochrome b-245 | Q68027439 | ||
An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs | Q22066003 | ||
DNA sequencing with chain-terminating inhibitors | Q22066207 | ||
Two cytosolic neutrophil oxidase components absent in autosomal chronic granulomatous disease | Q24293151 | ||
Cloning of a 67-kD neutrophil oxidase factor with similarity to a noncatalytic region of p60c-src | Q24300397 | ||
Characterization of the 47-kilodalton autosomal chronic granulomatous disease protein: tissue-specific expression and transcriptional control by retinoic acid | Q24597756 | ||
Improved tools for biological sequence comparison | Q24652199 | ||
Identification of a ten-amino acid proline-rich SH3 binding site | Q28266446 | ||
P433 | issue | 3 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | cell biology | Q7141 |
Neutrophil cytosolic factor 1 | Q21104738 | ||
Neutrophil cytosolic factor 2 | Q21114554 | ||
Neutrophil cytosolic factor 4 | Q21120096 | ||
P304 | page(s) | 557-61 | |
P577 | publication date | 1993-12-15 | |
P1433 | published in | Biochemical Journal | Q864221 |
P1476 | title | p40phox, a third cytosolic component of the activation complex of the NADPH oxidase to contain src homology 3 domains | |
P478 | volume | 296 ( Pt 3) |
Q24679525 | 156Pro-->Gln substitution in the light chain of cytochrome b558 of the human NADPH oxidase (p22-phox) leads to defective translocation of the cytosolic proteins p47-phox and p67-phox |
Q28214913 | A 29-kDa protein associated with p67phox expresses both peroxiredoxin and phospholipase A2 activity and enhances superoxide anion production by a cell-free system of NADPH oxidase activity |
Q28300890 | A 68-kDa kinase and NADPH oxidase component p67phox are targets for Cdc42Hs and Rac1 in neutrophils |
Q36685379 | A domain of p47phox that interacts with human neutrophil flavocytochrome b558. |
Q30164072 | A molecular mechanism for autoinhibition of the tandem SH3 domains of p47phox, the regulatory subunit of the phagocyte NADPH oxidase |
Q24533279 | A new method for isolating tyrosine kinase substrates used to identify fish, an SH3 and PX domain-containing protein, and Src substrate |
Q24561483 | A p47-phox pseudogene carries the most common mutation causing p47-phox- deficient chronic granulomatous disease |
Q24296133 | A region C-terminal to the proline-rich core of p47phox regulates activation of the phagocyte NADPH oxidase by interacting with the C-terminal SH3 domain of p67phox |
Q28297425 | Activation and assembly of the NADPH oxidase: a structural perspective |
Q41682732 | Activation of human neutrophil NADPH oxidase by phosphatidic acid or diacylglycerol in a cell-free system. Activity of diacylglycerol is dependent on its conversion to phosphatidic acid |
Q24294214 | Activation state-dependent interaction between Galphai and p67phox |
Q30176967 | An SH3 domain-mediated interaction between the phagocyte NADPH oxidase factors p40phox and p47phox |
Q34007682 | Analysis of microdissected neurons by 18O mass spectrometry reveals altered protein expression in Alzheimer's disease |
Q28215817 | Architecture of the p40-p47-p67phox complex in the resting state of the NADPH oxidase. A central role for p67phox |
Q30176886 | Assembly of the human neutrophil NADPH oxidase involves binding of p67phox and flavocytochrome b to a common functional domain in p47phox. |
Q34338562 | Assembly of the phagocyte NADPH oxidase |
Q44854788 | Binding of FAD to cytochrome b558 is facilitated during activation of the phagocyte NADPH oxidase, leading to superoxide production |
Q40975170 | Biosynthesis of flavocytochrome b558 . gp91(phox) is synthesized as a 65-kDa precursor (p65) in the endoplasmic reticulum. |
Q34018461 | Cell-free activation of neutrophil NADPH oxidase by a phosphatidic acid-regulated protein kinase |
Q42662658 | Characteristics of NADPH oxidase genes (Nox2, p22, p47, and p67) and Nox4 gene expressed in blood cells of juvenile Ciona intestinalis |
Q40094185 | Characterization of a mutation in the Phox homology domain of the NADPH oxidase component p40phox identifies a mechanism for negative regulation of superoxide production |
Q21245653 | Chronic Granulomatous Disease; fundamental stages in our understanding of CGD |
Q42016380 | Comparison of macrophage antimicrobial responses induced by type II interferons of the goldfish (Carassius auratus L.). |
Q45940843 | Comparison of proton channel, phagocyte oxidase, and respiratory burst levels between human eosinophil and neutrophil granulocytes. |
Q59512302 | Components and organization of the nadph oxidase of phagocytic cells |
Q28273527 | Cryptic Rac-binding and p21(Cdc42Hs/Rac)-activated kinase phosphorylation sites of NADPH oxidase component p67(phox) |
Q36426212 | Crystallization and preliminary crystallographic analysis of p40phox, a regulatory subunit of NADPH oxidase |
Q44052605 | Cytosolic phospholipase A2 (cPLA2) regulation of human monocyte NADPH oxidase activity. cPLA2 affects translocation but not phosphorylation of p67(phox) and p47(phox). |
Q57716457 | Deciphering the disease-related molecular networks using urine proteomics |
Q40792524 | Deletion of a novel protein kinase with PX and FYVE-related domains increases the rate of differentiation of Trypanosoma brucei |
Q28139055 | Demonstration of the interaction of thioredoxin with p40phox, a phagocyte oxidase component, using a yeast two-hybrid system |
Q53419135 | Despite structural similarities between gp91phox and FRE1, flavocytochrome b558 does not mediate iron uptake by myeloid cells. |
Q78044659 | Detection of oxidant producing-sites in glutaraldehyde-fixed human neutrophils and eosinophils stimulated with phorbol myristate acetate |
Q73695200 | Detection of superoxide and NADPH oxidase in porcine articular chondrocytes |
Q27022012 | Detection of superoxide anion and hydrogen peroxide production by cellular NADPH oxidases |
Q36367432 | Disturbed interaction of p21-rac with mutated p67-phox causes chronic granulomatous disease |
Q24338397 | Effects of p47phox C terminus phosphorylations on binding interactions with p40phox and p67phox. Structural and functional comparison of p40phox and p67phox SH3 domains |
Q42484955 | Expression and modulation of an NADPH oxidase in mammalian astrocytes. |
Q28260493 | Genetic and mutational heterogeneity of autosomal recessive chronic granulomatous disease in Tunisia |
Q28547554 | INF-γ Enhances Nox2 Activity by Upregulating phox Proteins When Applied to Differentiating PLB-985 Cells but Does Not Induce Nox2 Activity by Itself |
Q61701708 | Identification and functional characterization of two novel mutations in the α-helical loop (residues 484-503) of CYBB/gp91phox resulting in the rare X91+ variant of chronic granulomatous disease |
Q28141425 | Identification of a splice variant mRNA of p40phox, an NADPH oxidase component of phagocytes |
Q37968311 | Insights into the PX (phox-homology) domain and SNX (sorting nexin) protein families: structures, functions and roles in disease |
Q28579361 | Interaction of protein kinase C zeta with ZIP, a novel protein kinase C-binding protein |
Q30176875 | Interactions between cytosolic components of the NADPH oxidase: p40phox interacts with both p67phox and p47phox |
Q41195261 | Interactions between the components of the human NADPH oxidase: intrigues in the phox family |
Q30176831 | Involvement of p40phox in activation of phagocyte NADPH oxidase through association of its carboxyl-terminal, but not its amino-terminal, with p67phox |
Q46292651 | Kinase-dependent activation of the leukocyte NADPH oxidase in a cell-free system. Phosphorylation of membranes and p47(PHOX) during oxidase activation |
Q41172741 | Knockout of p47 phox uncovers a critical role of p40 phox in reactive oxygen species production in microvascular endothelial cells |
Q30193582 | Mapping the domains of interaction of p40phox with both p47phox and p67phox of the neutrophil oxidase complex using the two-hybrid system. |
Q24534192 | Mechanisms of NADPH oxidase activation: translocation of p40phox, Rac1 and Rac2 from the cytosol to the membranes in human neutrophils lacking p47phox or p67phox |
Q43984235 | Molecular and functional characterization of a new X-linked chronic granulomatous disease variant (X91+) case with a double missense mutation in the cytosolic gp91phox C-terminal tail. |
Q31965773 | Molecular cloning and identification of bottle-nosed dolphin p40(phox), p47(phox) and p67(phox). |
Q30177020 | Multiple SH3 domain interactions regulate NADPH oxidase assembly in whole cells |
Q40963048 | Mutagenesis of an arginine- and lysine-rich domain in the gp91(phox) subunit of the phagocyte NADPH-oxidase flavocytochrome b558. |
Q22003963 | Mutation at histidine 338 of gp91(phox) depletes FAD and affects expression of cytochrome b558 of the human NADPH oxidase |
Q31883583 | Mutational analysis of patients with p47-phox-deficient chronic granulomatous disease: The significance of recombination events between the p47-phox gene (NCF1) and its highly homologous pseudogenes |
Q34391668 | NADPH oxidase and the respiratory burst |
Q44602831 | NADPH oxidase immunoreactivity in the mouse brain |
Q38394359 | NADPH oxidases and cancer |
Q90576094 | NADPH oxidases and oxidase crosstalk in cardiovascular diseases: novel therapeutic targets |
Q33632660 | NADPH oxidases: a perspective on reactive oxygen species production in tumor biology |
Q36302873 | NADPH oxidases: an overview from structure to innate immunity-associated pathologies |
Q36699741 | NLRP1 and NLRP3 inflammasomes are essential for distinct outcomes of decreased cytokines but enhanced bacterial killing upon chronic Nod2 stimulation |
Q39546057 | NOX, NOX Who is There? The Contribution of NADPH Oxidase One to Beta Cell Dysfunction |
Q35985407 | NOX2 As a Target for Drug Development: Indications, Possible Complications, and Progress |
Q38221176 | Neutrophils at work |
Q39797688 | Neutrophils exposed to bacterial lipopolysaccharide upregulate NADPH oxidase assembly |
Q36228786 | Neutrophils from p40phox-/- mice exhibit severe defects in NADPH oxidase regulation and oxidant-dependent bacterial killing. |
Q24674641 | Novel domains in NADPH oxidase subunits, sorting nexins, and PtdIns 3-kinases: binding partners of SH3 domains? |
Q24291510 | Novel modular domain PB1 recognizes PC motif to mediate functional protein-protein interactions |
Q45256930 | Oxidase activity in cord blood neutrophils: a balance between increased membrane associated cytochrome b558 and deficient cytosolic components |
Q31440107 | Oxygen radical generation and expression of NADPH oxidase genes in bottlenose dolphin (Tursiops truncatus) neutrophils |
Q24312088 | PB1 domain-mediated heterodimerization in NADPH oxidase and signaling complexes of atypical protein kinase C with Par6 and p62 |
Q24655677 | PU.1 as an essential activator for the expression of gp91(phox) gene in human peripheral neutrophils, monocytes, and B lymphocytes |
Q28243008 | PU.1 is essential for p47(phox) promoter activity in myeloid cells |
Q33508823 | Phagocytosis of Streptococcus pyogenes by all-trans retinoic acid-differentiated HL-60 cells: roles of azurophilic granules and NADPH oxidase |
Q30156016 | Phosphorylation of threonine 154 in p40phox is an important physiological signal for activation of the neutrophil NADPH oxidase |
Q37184540 | Priming of the neutrophil NADPH oxidase activation: role of p47phox phosphorylation and NOX2 mobilization to the plasma membrane |
Q30429784 | Probing the role of the carboxyl terminus of the gp91phox subunit of neutrophil flavocytochrome b558 using site-directed mutagenesis |
Q30164819 | Properties of phagocyte NADPH oxidase p47-phox mutants with unmasked SH3 (Src homology 3) domains: full reconstitution of oxidase activity in a semi-recombinant cell-free system lacking arachidonic acid |
Q57057849 | PtdIns(3)P regulates the neutrophil oxidase complex by binding to the PX domain of p40phox |
Q42056199 | Rac1, and not Rac2, is involved in the regulation of the intracellular hydrogen peroxide level in HepG2 cells |
Q36801016 | Reactive oxygen species in phagocytic leukocytes |
Q36865824 | Regulation of Nox and Duox enzymatic activity and expression |
Q40990951 | Role of histidines identified by mutagenesis in the NADPH oxidase-associated H+ channel |
Q39061512 | Rosiglitazone induces cardiotoxicity by accelerated apoptosis |
Q30193848 | SH3-dependent assembly of the phagocyte NADPH oxidase |
Q47707553 | Signal transduction and activation of the NADPH oxidase in eosinophils |
Q41666467 | Simultaneous presence of p47(phox) and flavocytochrome b-245 are required for the activation of NADPH oxidase by anionic amphiphiles. Evidence for an intermediate state of oxidase activation |
Q46085356 | Six different CYBA mutations including three novel mutations in ten families from Turkey, resulting in autosomal recessive chronic granulomatous disease. |
Q39037945 | Staphylococcus aureus, phagocyte NADPH oxidase and chronic granulomatous disease |
Q27633813 | Structure and ligand recognition of the PB1 domain: a novel protein module binding to the PC motif |
Q27628646 | Structure of the TPR domain of p67phox in complex with Rac.GTP |
Q28282131 | Structure, regulation and evolution of Nox-family NADPH oxidases that produce reactive oxygen species |
Q42427499 | Subcellular localisation of the p40phox component of NADPH oxidase involves direct interactions between the Phox homology domain and F-actin |
Q34455923 | Superoxide generation of phagocytes and nonphagocytic cells |
Q33217673 | Superoxide production in Galleria mellonella hemocytes: identification of proteins homologous to the NADPH oxidase complex of human neutrophils |
Q36051340 | Synaptic localization of a functional NADPH oxidase in the mouse hippocampus |
Q48392309 | Systematic discovery of functional modules and context-specific functional annotation of human genome |
Q28254731 | The 40-kDa component of the phagocyte NADPH oxidase (p40phox) is phosphorylated during activation in differentiated HL60 cells |
Q90546431 | The Emerging Roles of Nicotinamide Adenine Dinucleotide Phosphate Oxidase 2 in Skeletal Muscle Redox Signaling and Metabolism |
Q40410144 | The NADPH oxidase complex of phagocytic leukocytes: a biochemical and cytochemical view |
Q35828194 | The NADPH oxidase of professional phagocytes--prototype of the NOX electron transport chain systems |
Q43727523 | The NOD2insC polymorphism is associated with worse outcome following ileal pouch-anal anastomosis for ulcerative colitis |
Q27642246 | The PB1 domain and the PC motif-containing region are structurally similar protein binding modules |
Q30165057 | The adaptor protein p40(phox) as a positive regulator of the superoxide-producing phagocyte oxidase. |
Q42123357 | The major phosphorylation site of the NADPH oxidase component p67phox is Thr233. |
Q45887694 | The molecular basis of chronic granulomatous disease |
Q30159700 | The phosphoinositide-binding protein p40phox activates the NADPH oxidase during FcgammaIIA receptor-induced phagocytosis |
Q30193854 | The regulation of superoxide production by the NADPH oxidase of neutrophils and other mammalian cells |
Q43694414 | Transcriptional regulation of the p67phox gene: role of AP-1 in concert with myeloid-specific transcription factors |
Q28300475 | Translocation of guinea pig p40-phox during activation of NADPH oxidase |
Q35083719 | Transplasma membrane electron transport: enzymes involved and biological function. |
Q24314825 | p110δ, a novel phosphoinositide 3-kinase in leukocytes |
Q42996911 | p40(phox) Participates in the activation of NADPH oxidase by increasing the affinity of p47(phox) for flavocytochrome b(558). |
Q28306699 | p40(phox) down-regulates NADPH oxidase activity through interactions with its SH3 domain |
Q24292834 | p40phox as an alternative organizer to p47phox in Nox2 activation: a new mechanism involving an interaction with p22phox |
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