| scholarly article | Q13442814 |
| P2093 | author name string | R Lührmann | |
| O V Makarova | |||
| E M Makarov | |||
| P2860 | cites work | Molecular characterization of an autoallergen, Hom s 1, identified by serum IgE from atopic dermatitis patients | Q22008550 |
| A novel genetic screen for snRNP assembly factors in yeast identifies a conserved protein, Sad1p, also required for pre-mRNA splicing | Q22008761 | ||
| Sm and Sm-like proteins assemble in two related complexes of deep evolutionary origin | Q22009995 | ||
| A doughnut-shaped heteromer of human Sm-like proteins binds to the 3'-end of U6 snRNA, thereby facilitating U4/U6 duplex formation in vitro | Q22010663 | ||
| The 20kD protein of human [U4/U6.U5] tri-snRNPs is a novel cyclophilin that forms a complex with the U4/U6-specific 60kD and 90kD proteins | Q24312016 | ||
| The human U5 snRNP-specific 100-kD protein is an RS domain-containing, putative RNA helicase with significant homology to the yeast splicing factor Prp28p | Q24316012 | ||
| snRNP Sm proteins share two evolutionarily conserved sequence motifs which are involved in Sm protein-protein interactions | Q24317255 | ||
| Functional expression of cloned human splicing factor SF2: homology to rna-binding proteins, U1 70K, and drosophila splicing regulators | Q24317722 | ||
| An evolutionarily conserved U5 snRNP-specific protein is a GTP-binding factor closely related to the ribosomal translocase EF-2. | Q24318957 | ||
| The HeLa 200 kDa U5 snRNP-specific protein and its homologue in Saccharomyces cerevisiae are members of the DEXH-box protein family of putative RNA helicases | Q24324586 | ||
| Functional interaction of a novel 15.5kD [U4/U6.U5] tri-snRNP protein with the 5' stem-loop of U4 snRNA | Q24529915 | ||
| Mammalian splicing factor SF3a120 represents a new member of the SURP family of proteins and is homologous to the essential splicing factor PRP21p of Saccharomyces cerevisiae. | Q24539048 | ||
| The human U4/U6 snRNP contains 60 and 90kD proteins that are structurally homologous to the yeast splicing factors Prp4p and Prp3p | Q24539217 | ||
| A new cyclophilin and the human homologues of yeast Prp3 and Prp4 form a complex associated with U4/U6 snRNPs | Q24539227 | ||
| Identification of an RNA-dependent ATPase activity in mammalian U5 snRNPs | Q24546120 | ||
| 20S small nuclear ribonucleoprotein U5 shows a surprisingly complex protein composition | Q24609558 | ||
| A gene encoding antigenic peptides of human squamous cell carcinoma recognized by cytotoxic T lymphocytes | Q24647420 | ||
| Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei | Q27860728 | ||
| Identification by mass spectrometry and functional analysis of novel proteins of the yeast [U4/U6.U5] tri-snRNP. | Q27937630 | ||
| Mechanical devices of the spliceosome: motors, clocks, springs, and things | Q27938081 | ||
| Purification of the yeast U4/U6.U5 small nuclear ribonucleoprotein particle and identification of its proteins | Q27939063 | ||
| Protein-protein interactions and 5'-splice-site recognition in mammalian mRNA precursors | Q28251112 | ||
| The superfamily of arginine/serine-rich splicing factors | Q29618794 | ||
| SR proteins and splicing control | Q29619936 | ||
| Protein functions in pre-mRNA splicing | Q29620262 | ||
| The structure and function of proteins involved in mammalian pre-mRNA splicing | Q29620286 | ||
| SR-related proteins and the processing of messenger RNA precursors | Q33765345 | ||
| 3'-terminal labelling of RNA with T4 RNA ligase | Q34273342 | ||
| The PROSITE database, its status in 1995. | Q34585880 | ||
| Functional interactions of Prp8 with both splice sites at the spliceosomal catalytic center | Q35203137 | ||
| SR proteins are sufficient for exon bridging across an intron | Q35905160 | ||
| Evidence that the 60-kDa protein of 17S U2 small nuclear ribonucleoprotein is immunologically and functionally related to the yeast PRP9 splicing factor and is required for the efficient formation of prespliceosomes | Q36518245 | ||
| Gel electrophoretic isolation of splicing complexes containing U1 small nuclear ribonucleoprotein particles | Q36783515 | ||
| Extensive interactions of PRP8 protein with the 5' and 3' splice sites during splicing suggest a role in stabilization of exon alignment by U5 snRNA. | Q38294598 | ||
| Primary structure of the human splicing factor asf reveals similarities with drosophila regulators | Q38334210 | ||
| The [U4/U6.U5] tri-snRNP-specific 27K protein is a novel SR protein that can be phosphorylated by the snRNP-associated protein kinase | Q42060574 | ||
| SR proteins escort the U4/U6.U5 tri-snRNP to the spliceosome | Q43205783 | ||
| In vitro reconstitution of snRNPs: a reconstituted U4/U6 snRNP participates in splicing complex formation. | Q50336095 | ||
| Cyclic 2',3'-phosphates and nontemplated nucleotides at the 3' end of spliceosomal U6 small nuclear RNA's | Q52443500 | ||
| Modification of acidic residues normalizes sodium dodecyl sulfate-polyacrylamide gel electrophoresis of caldesmon and other proteins that migrate anomalously | Q68220943 | ||
| P433 | issue | 10 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | molecular mass | Q182854 |
| Ubiquitin specific peptidase 39 | Q21125234 | ||
| spliceosome | Q915868 | ||
| P304 | page(s) | 2553-2563 | |
| P577 | publication date | 2001-05-01 | |
| P1433 | published in | The EMBO Journal | Q1278554 |
| P1476 | title | The 65 and 110 kDa SR-related proteins of the U4/U6.U5 tri-snRNP are essential for the assembly of mature spliceosomes | |
| P478 | volume | 20 |
| Q34010288 | A functional genomic screen reveals novel host genes that mediate interferon-alpha's effects against hepatitis C virus |
| Q24302596 | A human splicing factor, SKIP, associates with P-TEFb and enhances transcription elongation by HIV-1 Tat. |
| Q36823274 | A new HIF-1α/RANTES-driven pathway to hepatocellular carcinoma mediated by germline haploinsufficiency of SART1/HAF in mice |
| Q24299148 | A novel SR-related protein is required for the second step of Pre-mRNA splicing |
| Q28264738 | A proteomic study of SUMO-2 target proteins |
| Q37332858 | A role for ubiquitin in the spliceosome assembly pathway |
| Q39600802 | A single cell cycle genes homology region (CHR) controls cell cycle-dependent transcription of the cdc25C phosphatase gene and is able to cooperate with E2F or Sp1/3 sites |
| Q39633161 | A spliceosome intermediate with loosely associated tri-snRNP accumulates in the absence of Prp28 ATPase activity |
| Q24294927 | A subset of human 35S U5 proteins, including Prp19, function prior to catalytic step 1 of splicing |
| Q39452744 | A systems biology approach identifies SART1 as a novel determinant of both 5-fluorouracil and SN38 drug resistance in colorectal cancer. |
| Q92536533 | An Allosteric Network for Spliceosome Activation Revealed by High-Throughput Suppressor Analysis in Saccharomyces cerevisiae |
| Q24540060 | Biochemical and genetic analyses of the U5, U6, and U4/U6 x U5 small nuclear ribonucleoproteins from Saccharomyces cerevisiae |
| Q35813276 | Broad specificity of SR (serine/arginine) proteins in the regulation of alternative splicing of pre-messenger RNA. |
| Q24338153 | CIR, a corepressor of CBF1, binds to PAP-1 and effects alternative splicing |
| Q34700967 | Cell cycle abnormalities associated with differential perturbations of the human U5 snRNP associated U5-200kD RNA helicase |
| Q34146146 | Characterization of purified human Bact spliceosomal complexes reveals compositional and morphological changes during spliceosome activation and first step catalysis |
| Q24515041 | Comparative genomics and evolution of proteins involved in RNA metabolism |
| Q24300333 | Crooked neck is a component of the human spliceosome and implicated in the splicing process |
| Q27641709 | Crystal structure of a complex between human spliceosomal cyclophilin H and a U4/U6 snRNP-60K peptide |
| Q28547435 | Cwf16p Associating with the Nineteen Complex Ensures Ordered Exon Joining in Constitutive Pre-mRNA Splicing in Fission Yeast |
| Q38103253 | Decoding ubiquitin for mitosis |
| Q24304372 | Distinct and overlapping sets of SUMO-1 and SUMO-2 target proteins revealed by quantitative proteomics |
| Q52647713 | Downregulation of ubiquitin-specific peptidase 39 suppresses the proliferation and induces the apoptosis of human colorectal cancer cells. |
| Q36315971 | Dynamic interactions of Ntr1-Ntr2 with Prp43 and with U5 govern the recruitment of Prp43 to mediate spliceosome disassembly |
| Q24306136 | Dynamic protein-protein interaction wiring of the human spliceosome |
| Q37547706 | Expression of Interferon Effector Gene SART1 Correlates with Interferon Treatment Response against Hepatitis B Infection. |
| Q43088927 | Functional genomics identifies a requirement of pre-mRNA splicing factors for sister chromatid cohesion |
| Q34547657 | Functional links between the Prp19-associated complex, U4/U6 biogenesis, and spliceosome recycling. |
| Q27865260 | Functional mammalian spliceosomal complex E contains SMN complex proteins in addition to U1 and U2 snRNPs. |
| Q38993788 | Functions and regulation of the Brr2 RNA helicase during splicing |
| Q27935130 | Genetic analysis reveals a role for the C terminus of the Saccharomyces cerevisiae GTPase Snu114 during spliceosome activation |
| Q37450692 | HAF : the new player in oxygen-independent HIF-1alpha degradation |
| Q33673175 | High expression of ubiquitin-specific peptidase 39 is associated with the development of vascular remodeling |
| Q43649668 | Human PRP4 kinase is required for stable tri-snRNP association during spliceosomal B complex formation |
| Q39674598 | Human U4/U6.U5 and U4atac/U6atac.U5 tri-snRNPs exhibit similar protein compositions |
| Q36994805 | Hypoxia-associated factor, a novel E3-ubiquitin ligase, binds and ubiquitinates hypoxia-inducible factor 1alpha, leading to its oxygen-independent degradation |
| Q36489201 | Hypoxia-regulated components of the U4/U6.U5 tri-small nuclear riboprotein complex: possible role in autosomal dominant retinitis pigmentosa |
| Q39744901 | ICP27 interacts with SRPK1 to mediate HSV splicing inhibition by altering SR protein phosphorylation |
| Q47846564 | Identification of a 35S U4/U6.U5 tri-small nuclear ribonucleoprotein (tri-snRNP) complex intermediate in spliceosome assembly |
| Q30360791 | Identification of a small molecule inhibitor that stalls splicing at an early step of spliceosome activation. |
| Q38755963 | Knockdown of USP39 induces cell cycle arrest and apoptosis in melanoma |
| Q33556192 | Knockdown of ubiquitin-specific peptidase 39 inhibited the growth of osteosarcoma cells and induced apoptosis in vitro |
| Q38885249 | Lentivirus mediated silencing of ubiquitin specific peptidase 39 inhibits cell proliferation of human hepatocellular carcinoma cells in vitro |
| Q73813225 | Mapping QTLs and candidate genes for rice root traits under different water-supply conditions and comparative analysis across three populations |
| Q37620684 | Multiple components of the spliceosome regulate Mcl1 activity in neuroblastoma |
| Q39675127 | Multiple roles for SR proteins in trans splicing |
| Q59006843 | New components of the spliced leader RNP required for nematode trans-splicing |
| Q28534783 | New insights into the RNA-based mechanism of action of the anticancer drug 5'-fluorouracil in eukaryotic cells |
| Q38197052 | Novel regulatory principles of the spliceosomal Brr2 RNA helicase and links to retinal disease in humans |
| Q37225467 | Overexpression of USP39 predicts poor prognosis and promotes tumorigenesis of prostate cancer via promoting EGFR mRNA maturation and transcription elongation |
| Q51072666 | PKR activation and eIF2α phosphorylation mediate human globin mRNA splicing at spliceosome assembly. |
| Q46634476 | Phosphorylation of human PRP28 by SRPK2 is required for integration of the U4/U6-U5 tri-snRNP into the spliceosome |
| Q24292373 | Protein 61K, encoded by a gene (PRPF31) linked to autosomal dominant retinitis pigmentosa, is required for U4/U6*U5 tri-snRNP formation and pre-mRNA splicing |
| Q24296676 | Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis |
| Q38699941 | Putative role of SUMOylation in controlling the activity of deubiquitinating enzymes in cancer |
| Q37692001 | RBM25 Mediates Abiotic Responses in Plants |
| Q92093056 | RNA splicing factor USP39 promotes glioma progression by inducing TAZ mRNA maturation |
| Q24299534 | RNAi knockdown of hPrp31 leads to an accumulation of U4/U6 di-snRNPs in Cajal bodies |
| Q38841177 | Reduced USP39 expression inhibits malignant proliferation of medullary thyroid carcinoma in vitro |
| Q27668022 | Role of the ubiquitin-like protein Hub1 in splice-site usage and alternative splicing |
| Q38757480 | Roles of Sumoylation in mRNA Processing and Metabolism |
| Q90102232 | SNRP-27, the C. elegans homolog of the tri-snRNP 27K protein, has a role in 5' splice site positioning in the spliceosome |
| Q37546093 | Sad1 counteracts Brr2-mediated dissociation of U4/U6.U5 in tri-snRNP homeostasis |
| Q92602462 | Smu1 and RED are required for activation of spliceosomal B complexes assembled on short introns |
| Q38296438 | Stable tri-snRNP integration is accompanied by a major structural rearrangement of the spliceosome that is dependent on Prp8 interaction with the 5' splice site |
| Q60917803 | Structural and Functional Insights into Human Nuclear Cyclophilins |
| Q55001411 | Structural dynamics of the N-terminal domain and the Switch loop of Prp8 during spliceosome assembly and activation. |
| Q98564287 | Systematic characterization of the branch point binding protein, splicing factor 1, gene family in plant development and stress responses |
| Q55137359 | Targeting the spliceosome for cutaneous squamous cell carcinoma therapy: a role for c-MYC and wild-type p53 in determining the degree of tumour selectivity. |
| Q27940003 | The Clf1p splicing factor promotes spliceosome assembly through N-terminal tetratricopeptide repeat contacts |
| Q26970797 | The Dengue Virus NS5 Protein Intrudes in the Cellular Spliceosome and Modulates Splicing |
| Q21183897 | The SR protein family |
| Q38637779 | The biochemistry of blister fluid from pediatric burn injuries: proteomics and metabolomics aspects. |
| Q26766125 | The business of deubiquitination - location, location, location |
| Q27683986 | The conserved ubiquitin-like protein Hub1 plays a critical role in splicing in human cells |
| Q27682659 | The crystal structure of S. cerevisiae Sad1, a catalytically inactive deubiquitinase that is broadly required for pre-mRNA splicing |
| Q37843675 | The function of spliceosome components in open mitosis |
| Q39554922 | The hypoxia-associated factor switches cells from HIF-1α- to HIF-2α-dependent signaling promoting stem cell characteristics, aggressive tumor growth and invasion |
| Q37955947 | The many roles of the highly interactive HSV protein ICP27, a key regulator of infection |
| Q24548787 | The network of protein-protein interactions within the human U4/U6.U5 tri-snRNP |
| Q36268425 | USP39 Deubiquitinase Is Essential for KRAS Oncogene-driven Cancer. |
| Q37735108 | USP39 regulates the growth of SMMC-7721 cells via FoxM1. |
| Q34486872 | Ubiquitin binding by a variant Jab1/MPN domain in the essential pre-mRNA splicing factor Prp8p |
| Q24336844 | Ubiquitin-like protein Hub1 is required for pre-mRNA splicing and localization of an essential splicing factor in fission yeast |
| Q38746245 | Ubiquitin-specific protease 39 is overexpressed in human lung cancer and promotes tumor cell proliferation in vitro |
| Q33797859 | Zebrafish usp39 mutation leads to rb1 mRNA splicing defect and pituitary lineage expansion |
| Q21134952 | hnRNP A1 and hnRNP F modulate the alternative splicing of exon 11 of the insulin receptor gene |
| Q44950735 | p53 is activated in response to disruption of the pre-mRNA splicing machinery. |
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