| scholarly article | Q13442814 |
| P50 | author | Reinhard Georg Lührmann | Q1317944 |
| Henning Urlaub | Q28037184 | ||
| Andrius Krasauskas | Q55164693 | ||
| Cindy L Will | Q63134178 | ||
| P2093 | author name string | Holger Stark | |
| Bjoern Sander | |||
| Monika M Golas | |||
| Sergey Bessonov | |||
| Maria Anokhina | |||
| P2860 | cites work | A subset of human 35S U5 proteins, including Prp19, function prior to catalytic step 1 of splicing | Q24294927 |
| Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis | Q24296676 | ||
| Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes | Q24298731 | ||
| Phosphorylation of spliceosomal protein SAP 155 coupled with splicing catalysis | Q24316022 | ||
| An evolutionarily conserved U5 snRNP-specific protein is a GTP-binding factor closely related to the ribosomal translocase EF-2. | Q24318957 | ||
| Pombe Cdc5-related protein. A putative human transcription factor implicated in mitogen-activated signaling | Q24321290 | ||
| The human U5-200kD DEXH-box protein unwinds U4/U6 RNA duplices in vitro | Q24323409 | ||
| The 65 and 110 kDa SR-related proteins of the U4/U6.U5 tri-snRNP are essential for the assembly of mature spliceosomes | Q24534416 | ||
| A novel U2 and U11/U12 snRNP protein that associates with the pre-mRNA branch site. | Q24535663 | ||
| A cyclophilin functions in pre-mRNA splicing | Q24536168 | ||
| Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs. | Q24537200 | ||
| Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei | Q27860728 | ||
| RNA unwinding in U4/U6 snRNPs requires ATP hydrolysis and the DEIH-box splicing factor Brr2 | Q27930438 | ||
| Spliceosome activation by PRP2 ATPase prior to the first transesterification reaction of pre-mRNA splicing | Q27931041 | ||
| Genetic analysis reveals a role for the C terminus of the Saccharomyces cerevisiae GTPase Snu114 during spliceosome activation | Q27935130 | ||
| Reconstitution of both steps of Saccharomyces cerevisiae splicing with purified spliceosomal components | Q27937542 | ||
| Mechanical devices of the spliceosome: motors, clocks, springs, and things | Q27938081 | ||
| The Prp19p-associated complex in spliceosome activation | Q27938109 | ||
| Functional and physical interactions between components of the Prp19p-associated complex | Q27939341 | ||
| The final stages of spliceosome maturation require Spp2p that can interact with the DEAH box protein Prp2p and promote step 1 of splicing | Q27939776 | ||
| A new generation of the IMAGIC image processing system | Q28131751 | ||
| The spliceosome: design principles of a dynamic RNP machine | Q28131809 | ||
| Molecular Architecture of the Multiprotein Splicing Factor SF3b | Q28203446 | ||
| A mammalian homolog of fission yeast Cdc5 regulates G2 progression and mitotic entry | Q28262254 | ||
| Pre-mRNA splicing: awash in a sea of proteins | Q29547272 | ||
| Multivariate statistical classification of noisy images (randomly oriented biological macromolecules). | Q30412687 | ||
| Conservation of the protein composition and electron microscopy structure of Drosophila melanogaster and human spliceosomal complexes | Q33382329 | ||
| Cell cycle-dependent phosphorylation of human CDC5 regulates RNA processing. | Q34133161 | ||
| Formation of the yeast splicing complex A1 and association of the splicing factor PRP19 with the pre-mRNA are independent of the 3' region of the intron | Q34825409 | ||
| The evolutionarily conserved core design of the catalytic activation step of the yeast spliceosome | Q35014709 | ||
| Phosphorylation-dependent control of the pre-mRNA splicing machinery | Q35031515 | ||
| The EF-G-like GTPase Snu114p regulates spliceosome dynamics mediated by Brr2p, a DExD/H box ATPase | Q37183473 | ||
| "Nought may endure but mutability": spliceosome dynamics and the regulation of splicing | Q37197189 | ||
| Dynamic association of proteins with the pre-mRNA branch region | Q38301245 | ||
| Protein composition and electron microscopy structure of affinity-purified human spliceosomal B complexes isolated under physiological conditions | Q38406412 | ||
| Interaction between a G-patch protein and a spliceosomal DEXD/H-box ATPase that is critical for splicing | Q40419046 | ||
| An RNA switch at the 5' splice site requires ATP and the DEAD box protein Prp28p | Q41607972 | ||
| 3D cryo-EM structure of an active step I spliceosome and localization of its catalytic core | Q41616762 | ||
| GraFix: sample preparation for single-particle electron cryomicroscopy | Q41623539 | ||
| trans-splicing to spliceosomal U2 snRNA suggests disruption of branch site-U2 pairing during pre-mRNA splicing | Q42381501 | ||
| The ribosomal translocase homologue Snu114p is involved in unwinding U4/U6 RNA during activation of the spliceosome | Q42724676 | ||
| Release of SF3 from the intron branchpoint activates the first step of pre-mRNA splicing | Q42914749 | ||
| The Prp19-associated complex is required for specifying interactions of U5 and U6 with pre-mRNA during spliceosome activation | Q46580672 | ||
| Small nuclear ribonucleoprotein remodeling during catalytic activation of the spliceosome. | Q50336089 | ||
| Isolation of an active step I spliceosome and composition of its RNP core. | Q50336090 | ||
| SIGNATURE: a single-particle selection system for molecular electron microscopy. | Q51936620 | ||
| Specific alterations of U1-C protein or U1 small nuclear RNA can eliminate the requirement of Prp28p, an essential DEAD box splicing factor | Q73427972 | ||
| Corrim-based alignment for improved speed in single-particle image processing | Q79195381 | ||
| The splicing factor Prp17 interacts with the U2, U5 and U6 snRNPs and associates with the spliceosome pre- and post-catalysis | Q81762656 | ||
| P433 | issue | 12 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | spliceosome | Q915868 |
| P304 | page(s) | 2384-2403 | |
| P577 | publication date | 2010-10-27 | |
| P1433 | published in | RNA | Q7277164 |
| P1476 | title | Characterization of purified human Bact spliceosomal complexes reveals compositional and morphological changes during spliceosome activation and first step catalysis | |
| P478 | volume | 16 |
| Q33285649 | A composite double-/single-stranded RNA-binding region in protein Prp3 supports tri-snRNP stability and splicing |
| Q41510811 | A new role for FBP21 as regulator of Brr2 helicase activity |
| Q41746776 | A protein map of the yeast activated spliceosome as obtained by electron microscopy |
| Q35826664 | A quantitative high-throughput in vitro splicing assay identifies inhibitors of spliceosome catalysis |
| Q39633161 | A spliceosome intermediate with loosely associated tri-snRNP accumulates in the absence of Prp28 ATPase activity |
| Q36076436 | ATPγS stalls splicing after B complex formation but prior to spliceosome activation |
| Q92990603 | Alternative splicing of P2RX7 pre-messenger RNA in health and diseases: Myth or reality? |
| Q42215951 | Antisense-targeted immuno-EM localization of the pre-mRNA path in the spliceosomal C complex |
| Q48162917 | Arabidopsis MAS2, an Essential Gene That Encodes a Homolog of Animal NF-κ B Activating Protein, Is Involved in 45S Ribosomal DNA Silencing. |
| Q27320065 | CACN-1/Cactin plays a role in Wnt signaling in C. elegans |
| Q35961918 | CTNNBL1 facilitates the association of CWC15 with CDC5L and is required to maintain the abundance of the Prp19 spliceosomal complex |
| Q35786116 | CWC22-dependent pre-mRNA splicing and eIF4A3 binding enables global deposition of exon junction complexes |
| Q27683637 | Cancer-relevant Splicing Factor CAPERα Engages the Essential Splicing Factor SF3b155 in a Specific Ternary Complex |
| Q92171251 | Cus2 enforces the first ATP-dependent step of splicing by binding to yeast SF3b1 through a UHM-ULM interaction |
| Q24301865 | Cwc2 and its human homologue RBM22 promote an active conformation of the spliceosome catalytic centre |
| Q41293984 | Cwc21p promotes the second step conformation of the spliceosome and modulates 3' splice site selection |
| Q35212551 | Dramatically reduced spliceosome in Cyanidioschyzon merolae |
| Q34132743 | Dynamic protein ligand interactions--insights from MS. |
| Q24306136 | Dynamic protein-protein interaction wiring of the human spliceosome |
| Q37581520 | Endogenous U2·U5·U6 snRNA complexes in S. pombe are intron lariat spliceosomes |
| Q35127142 | Facioscapulohumeral muscular dystrophy region gene 1 is a dynamic RNA-associated and actin-bundling protein |
| Q50295498 | Formation of an intermediate Spliceosomal C complex |
| Q30360791 | Identification of a small molecule inhibitor that stalls splicing at an early step of spliceosome activation. |
| Q37285978 | Influenza A Virus Polymerase Recruits the RNA Helicase DDX19 to Promote the Nuclear Export of Viral mRNAs |
| Q89721620 | Insights into the Involvement of Spliceosomal Mutations in Myelodysplastic Disorders from Analysis of SACY-1/DDX41 in Caenorhabditis elegans |
| Q34388431 | Intrinsic disorder in the human spliceosomal proteome |
| Q40047496 | Isolation and accumulation of spliceosomal assembly intermediates |
| Q41952380 | Mass spectrometry-based relative quantification of proteins in precatalytic and catalytically active spliceosomes by metabolic labeling (SILAC), chemical labeling (iTRAQ), and label-free spectral count |
| Q34467642 | Mechanisms and Regulation of Alternative Pre-mRNA Splicing |
| Q47738832 | Mechanistic insights into precursor messenger RNA splicing by the spliceosome |
| Q42288523 | Molecular architecture of zinc chelating small molecules that inhibit spliceosome assembly at an early stage |
| Q47121434 | Molecular basis of differential 3' splice site sensitivity to anti-tumor drugs targeting U2 snRNP. |
| Q40206494 | Multiple protein-protein interactions converging on the Prp38 protein during activation of the human spliceosome |
| Q97681153 | Mutations in FAM50A suggest that Armfield XLID syndrome is a spliceosomopathy |
| Q59135342 | NKAP functions as an oncogene and its expression is induced by CoCl 2 treatment in breast cancer via AKT/mTOR signaling pathway |
| Q37631850 | NKAP is a novel RS-related protein that interacts with RNA and RNA binding proteins |
| Q35956501 | Nuclear cyclophilins affect spliceosome assembly and function in vitro |
| Q46686083 | Post-transcriptional spliceosomes are retained in nuclear speckles until splicing completion |
| Q38716606 | Protein 4.1R Exon 16 3' Splice Site Activation Requires Coordination among TIA1, Pcbp1, and RBM39 during Terminal Erythropoiesis |
| Q47109806 | Proteogenomic analysis prioritises functional single nucleotide variants in cancer samples. |
| Q34042438 | Proteomic analysis reveals CACN-1 is a component of the spliceosome in Caenorhabditis elegans |
| Q34159087 | Psoromic acid derivatives: a new family of small-molecule pre-mRNA splicing inhibitors discovered by a stage-specific high-throughput in vitro splicing assay |
| Q89403803 | RES complex is associated with intron definition and required for zebrafish early embryogenesis |
| Q30556912 | RNA structure analysis of human spliceosomes reveals a compact 3D arrangement of snRNAs at the catalytic core |
| Q27938645 | Rapid screening of yeast mutants with reporters identifies new splicing phenotypes |
| Q28513387 | Rbfox1 downregulation and altered calpain 3 splicing by FRG1 in a mouse model of Facioscapulohumeral muscular dystrophy (FSHD) |
| Q34324094 | Rearrangements within human spliceosomes captured after exon ligation. |
| Q39262216 | Regulating distal tip cell migration in space and time |
| Q38194103 | Regulation of the circadian clock through pre-mRNA splicing in Arabidopsis |
| Q40091372 | Retention and splicing complex (RES) - the importance of cooperativity |
| Q100951831 | SON and SRRM2 are essential for nuclear speckle formation |
| Q34181884 | Semiquantitative proteomic analysis of the human spliceosome via a novel two-dimensional gel electrophoresis method |
| Q92602462 | Smu1 and RED are required for activation of spliceosomal B complexes assembled on short introns |
| Q36491462 | Spliceosome database: a tool for tracking components of the spliceosome |
| Q35786124 | Splicing diversity revealed by reduced spliceosomes in C. merolae and other organisms |
| Q38296438 | Stable tri-snRNP integration is accompanied by a major structural rearrangement of the spliceosome that is dependent on Prp8 interaction with the 5' splice site |
| Q42233861 | Stoichiometries of U2AF35, U2AF65 and U2 snRNP reveal new early spliceosome assembly pathways. |
| Q38099614 | Structural analyses of the pre-mRNA splicing machinery |
| Q42953862 | Structural and functional insights into the N-terminus of Schizosaccharomyces pombe Cdc5. |
| Q28315106 | Structural and mechanistic insights into human splicing factor SF3b complex derived using an integrated approach guided by the cryo-EM density maps |
| Q42286114 | Structural bioinformatics of the human spliceosomal proteome |
| Q27677135 | Structure and assembly of the SF3a splicing factor complex of U2 snRNP |
| Q27675626 | Structure of Phosphorylated SF1 Bound to U2AF65 in an Essential Splicing Factor Complex |
| Q47231251 | Structure of a human catalytic step I spliceosome |
| Q41597888 | Structure of a pre-catalytic spliceosome |
| Q27701867 | Structure of a yeast spliceosome at 3.6-angstrom resolution |
| Q49845089 | Structure of the human activated spliceosome in three conformational states. |
| Q57470604 | Structures of the human pre-catalytic spliceosome and its precursor spliceosome |
| Q27703519 | The 3.8 Å structure of the U4/U6.U5 tri-snRNP: Insights into spliceosome assembly and catalysis |
| Q28547584 | The 35S U5 snRNP Is Generated from the Activated Spliceosome during In vitro Splicing |
| Q27697579 | The RNA helicase Aquarius exhibits structural adaptations mediating its recruitment to spliceosomes |
| Q41472998 | The awakening of the CDK10/Cyclin M protein kinase |
| Q37947529 | The mechanism of the second step of pre-mRNA splicing |
| Q26741296 | The nuts and bolts of the endogenous spliceosome |
| Q26766200 | The organization and contribution of helicases to RNA splicing |
| Q35970320 | The spliceosome-activating complex: molecular mechanisms underlying the function of a pleiotropic regulator |
| Q37704918 | The spliceosome: disorder and dynamics defined |
| Q42264162 | The transition in spliceosome assembly from complex E to complex A purges surplus U1 snRNPs from alternative splice sites |
| Q34313064 | Tls1 regulates splicing of shelterin components to control telomeric heterochromatin assembly and telomere length. |
| Q34377737 | Whole-genome screening identifies proteins localized to distinct nuclear bodies |
| Q92875028 | XAB2 depletion induces intron retention in POLR2A to impair global transcription and promote cellular senescence |
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