Ribosome inactivation by ricin A chain: a sensitive method to assess the activity of wild-type and mutant polypeptides

scientific article

Ribosome inactivation by ricin A chain: a sensitive method to assess the activity of wild-type and mutant polypeptides is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/J.1460-2075.1989.TB03377.X
P932PMC publication ID400803
P698PubMed publication ID2714255

P2093author name stringRoberts LM
Lord JM
Krieg PA
Osborn RW
May MJ
Hartley MR
P2860cites workEvidence that glutamic acid 167 is an active-site residue of Shiga-like toxin IQ24651553
Functional messenger RNAs are produced by SP6in vitrotranscription of cloned cDNAsQ29620476
Ricin linked to monophosphopentamannose binds to fibroblast lysosomal hydrolase receptors, resulting in a cell-type-specific toxinQ33979118
Site of action of a Vero toxin (VT2) from Escherichia coli O157:H7 and of Shiga toxin on eukaryotic ribosomes. RNA N-glycosidase activity of the toxins.Q34049372
The ribonuclease activity of the cytotoxin alpha-sarcin. The characteristics of the enzymatic activity of alpha-sarcin with ribosomes and ribonucleic acids as substratesQ34054931
RNA N-glycosidase activity of ricin A-chain. Mechanism of action of the toxic lectin ricin on eukaryotic ribosomesQ34163395
Nucleotide sequence of the Shiga-like toxin genes of Escherichia coliQ34633814
Amino acid sequence of mammalian elongation factor 2 deduced from the cDNA sequence: homology with GTP-binding proteinsQ35615941
The structure of rat 28S ribosomal ribonucleic add inferred from the sequence of nuclotides in a geneQ35692624
Nucleotide sequence and promoter mapping of the Escherichia coli Shiga-like toxin operon of bacteriophage H-19B.Q36265701
Nucleotide sequence of cloned cDNA coding for preproricinQ36485194
Effect of molecular rotation on the vibration-vibration energy transfer in condensed mediaQ37337983
Conservation of the primary structure at the 3' end of 18S rRNA from eucaryotic cellsQ38358326
Ribosome-inactivating proteins up to dateQ39726585
Purification and properties of a translation inhibitor from wheat germQ40421906
The effect of capping and polyadenylation on the stability, movement and translation of synthetic messenger RNAs in Xenopus oocytes.Q40472195
Genomic cloning and characterization of a ricin gene from Ricinus communisQ40472529
Oligonucleotide-directed mutagenesis using M13-derived vectors: an efficient and general procedure for the production of point mutations in any fragment of DNA.Q40496939
The primary and secondary structure of yeast 26S rRNAQ40500898
Modification of ribosomal RNA by ribosome-inactivating proteins from plantsQ40544393
Speeding-up the sequencing of double-stranded DNA.Q40546743
Secretion in yeast: structural features influencing the post-translational translocation of prepro-alpha-factor in vitroQ41354207
The role of the transit peptide in the routing of precursors toward different chloroplast compartmentsQ41470999
Ornithine decarboxylase production in vitro by using mouse cDNAQ42036648
The determination of the molecular weight of ribonucleic acid by polyacrylamide-gel electrophoresis. The effects of changes in conformationQ42933911
Effects of some proteins that inactivate the eukaryotic ribosomeQ43833097
Protein synthesis in chloroplasts. V. Translation of messenger RNA for the large subunit of fraction I protein in a heterologous cell-free systemQ44467225
Ricin and Ricinus communis agglutinin subunits are all derived from a single-size polypeptide precursorQ47247499
Polypeptide synthesis with ribonuclease-digested ribosomesQ53829947
The mechanism of action of ricin and related toxic lectins on eukaryotic ribosomes. The site and the characteristics of the modification in 28 S ribosomal RNA caused by the toxins.Q54408348
[41] Preparation of a cell-free protein-synthesizing system from wheat germQ62058917
The synthesis of Ricinus communis agglutinin, cotranslational and posttranslational modification of agglutinin polypeptides.Q64972827
Effects of ricin on the ribosomal sites involved in the interaction of the elongation factorsQ67314468
Ribosome inactivation by the toxic lectins abrin and ricin. Kinetics of the enzymic activity of the toxin A-chainsQ67354558
Protective Effect of Elongation Factor 2 on the Inactivation of Ribosomes by the Toxic Lectins Abrin and RicinQ67462793
Differential ricin sensitivity of rat liver and wheat germ ribosomes in polyuridylic acid translationQ67671703
Synergy between immunotoxins prepared with native ricin A chains and chemically-modified ricin B chainsQ68955460
Expression of ricin A chain in Escherichia coliQ68957425
Rapid chemical probing of conformation in 16 S ribosomal RNA and 30 S ribosomal subunits using primer extensionQ68961173
The three-dimensional structure of ricin at 2.8 AQ68962681
Involvement of arginine residues in inhibition of protein synthesis by ricin A-chainQ69568689
Different base/base mismatches are corrected with different efficiencies by the methyl-directed DNA mismatch-repair system of E. coliQ70387562
Ricin-like plant toxins are evolutionarily related to single-chain ribosome-inhibiting proteins from PhytolaccaQ70714210
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)301-308
P577publication date1989-01-01
P1433published inThe EMBO JournalQ1278554
P1476titleRibosome inactivation by ricin A chain: a sensitive method to assess the activity of wild-type and mutant polypeptides
P478volume8

Reverse relations

cites work (P2860)
Q77586056A recombinant ribosome-inactivating protein from the plant Phytolacca dioica L. produced from a synthetic gene
Q35645525Analysis of the contribution of an amphiphilic alpha-helix to the structure and to the function of ricin A chain
Q33267808Characterisation of saporin genes: in vitro expression and ribosome inactivation
Q52174609Characterisation of the PsbX protein from Photosystem II and light regulation of its gene expression in higher plants.
Q54559764Characterization of prokaryotic recombinant Aspergillus ribotoxin alpha-sarcin.
Q54567409Comparison of ribosome-inactivating proteins in the induction of apoptosis.
Q34003464Conserved amino acid residues in ribosome-inactivating proteins from plants
Q51837861Cytotoxicity of ribosome-inactivating protein saporin is not mediated through alpha2-macroglobulin receptor.
Q37033233Determination by systematic deletion of the amino acids essential for catalysis by ricin A chain
Q33802605Engineered toxins "zymoxins" are activated by the HCV NS3 protease by removal of an inhibitory protein domain
Q36798511Enzymatic properties of ribosome-inactivating proteins (RIPs) and related toxins
Q60311719Exploiting retrograde transport of Shiga-like toxin 1 for the delivery of exogenous antigens into the MHC class I presentation pathway
Q48065900Expression of the type 2 metallothionein-like gene MT2 from Arabidopsis thaliana in Zn(2+)-metallothionein-deficient Synechococcus PCC 7942: putative role for MT2 in Zn2+ metabolism.
Q36973773Mapping the minimal contiguous gene segment that encodes functionally active Shiga-like toxin II
Q36165342Mutational analysis of the Shiga toxin and Shiga-like toxin II enzymatic subunits
Q40399524Pokeweed antiviral protein (PAP) mutations which permit E.coli growth do not eliminate catalytic activity towards prokaryotic ribosomes
Q41760432Purification, characterization and molecular cloning of trichoanguin, a novel type I ribosome-inactivating protein from the seeds of Trichosanthes anguina
Q35568279Ricin Poisoning
Q40647546Role of arginine 180 and glutamic acid 177 of ricin toxin A chain in enzymatic inactivation of ribosomes
Q40651036Role of glutamic acid 177 of the ricin toxin A chain in enzymatic inactivation of ribosomes
Q40420267Selective cleavage of closely-related mRNAs by synthetic ribozymes
Q27730899The N-glycosidase mechanism of ribosome-inactivating proteins implied by crystal structures of alpha-momorcharin
Q64109486The fungal ribonuclease-like effector protein CSEP0064/BEC1054 represses plant immunity and interferes with degradation of host ribosomal RNA
Q43777861The lectin gene family of Ricinus communis: cloning of a functional ricin gene and three lectin pseudogenes
Q34341195The proteasome cap RPT5/Rpt5p subunit prevents aggregation of unfolded ricin A chain.
Q84142600Trichosanthin functions as Th2-type adjuvant in induction of allergic airway inflammation
Q70885420Wheat ribosome-inactivating proteins: seed and leaf forms with different specificities and cofactor requirements
Q35462730Wild type RTA and less toxic variants have distinct requirements for Png1 for their depurination activity and toxicity in Saccharomyces cerevisiae

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