Mutational analysis of the Shiga toxin and Shiga-like toxin II enzymatic subunits

scientific article

Mutational analysis of the Shiga toxin and Shiga-like toxin II enzymatic subunits is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JB.172.6.3346-3350.1990
P932PMC publication ID209145
P698PubMed publication ID2345150

P2093author name stringS B Calderwood
M P Jackson
R L Deresiewicz
P2860cites workRibosome inactivation by ricin A chain: a sensitive method to assess the activity of wild-type and mutant polypeptidesQ24567536
Two toxin-converting phages from Escherichia coli O157:H7 strain 933 encode antigenically distinct toxins with similar biologic activitiesQ24646436
Evidence that glutamic acid 167 is an active-site residue of Shiga-like toxin IQ24651553
2 New M13 vectors for cloningQ27861042
Construction and characterization of amplifiable multicopy DNA cloning vehicles derived from the P15A cryptic miniplasmidQ29614535
Site of action of a Vero toxin (VT2) from Escherichia coli O157:H7 and of Shiga toxin on eukaryotic ribosomes. RNA N-glycosidase activity of the toxins.Q34049372
Cloning and sequencing of the genes for Shiga toxin from Shigella dysenteriae type 1.Q36194407
Cloning and sequencing of a Shiga-like toxin type II variant from Escherichia coli strain responsible for edema disease of swineQ36215407
Nucleotide sequence and promoter mapping of the Escherichia coli Shiga-like toxin operon of bacteriophage H-19B.Q36265701
Affinity purification and characterization of Shiga-like toxin II and production of toxin-specific monoclonal antibodiesQ36997934
In vivo formation of hybrid toxins comprising Shiga toxin and the Shiga-like toxins and role of the B subunit in localization and cytotoxic activityQ37006892
Characterization of monoclonal antibodies against Shiga-like toxin from Escherichia coliQ37031424
Shiga and Shiga-like toxinsQ37063416
Isolation and characterization of monoclonal antibodies to Shiga toxinQ37110126
Tinkering with enzymes: what are we learning?Q39656946
Quantitative microtiter cytotoxicity assay for Shigella toxin.Q40230921
Selection and characterization of ricin toxin A-chain mutations in Saccharomyces cerevisiaeQ40646196
Role of glutamic acid 177 of the ricin toxin A chain in enzymatic inactivation of ribosomesQ40651036
Protein expression in E. coli minicells by recombinant plasmidsQ41235725
Nucleotide sequence analysis of the structural genes for Shiga-like toxin I encoded by bacteriophage 933J from Escherichia coliQ42657348
Subunit structure of Shigella cytotoxin.Q50938170
The mechanism of action of ricin and related toxic lectins on eukaryotic ribosomes. The site and the characteristics of the modification in 28 S ribosomal RNA caused by the toxins.Q54408348
Purification and some properties of a Vero toxin from a human strain of Escherichia coli that is immunologically related to Shiga-like toxin II (VT2)Q57563891
Production of Shiga-Like Toxin by Escherichia coliQ57563903
The three-dimensional structure of ricin at 2.8 AQ68962681
Shiga toxin, Shiga-like toxin II variant, and ricin are all single-site RNA N-glycosidases of 28 S RNA when microinjected into Xenopus oocytesQ69481383
Oligonucleotide-Directed Mutagenesis: A Simple Method Using Two Oligonucleotide Primers and a Single-Stranded DNA TemplateQ72405563
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectmutational analysisQ1955810
P304page(s)3346-3350
P577publication date1990-06-01
P1433published inJournal of BacteriologyQ478419
P1476titleMutational analysis of the Shiga toxin and Shiga-like toxin II enzymatic subunits
P478volume172

Reverse relations

cites work (P2860)
Q36957798An enzymatic mutant of Shiga-like toxin II variant is a vaccine candidate for edema disease of swine
Q35586936Analysis of Shiga toxin subunit association by using hybrid A polypeptides and site-specific mutagenesis
Q33754052Construction and characterization of an isogenic slt-ii deletion mutant of enterohemorrhagic Escherichia coli.
Q71523093Direct detection of Shiga-like toxin-producing Escherichia coli in ground beef using the polymerase chain reaction
Q41770295Diverse phage-encoded toxins in a protective insect endosymbiont
Q26858938Do the A subunits contribute to the differences in the toxicity of Shiga toxin 1 and Shiga toxin 2?
Q82754354Enhanced immunogenicity of a novel Stx2Am-Stx1B fusion protein in a mice model of enterohemorrhagic Escherichia coli O157:H7 infection
Q36195757Enterotoxins in acute infective diarrhoea
Q36798511Enzymatic properties of ribosome-inactivating proteins (RIPs) and related toxins
Q48220960Genetic and Immunological Analysis of a Novel Variant of Shiga Toxin 1 from Bovine Escherichia coli Strains and Development of Bead‐ELISA to Detect the Variant Toxin
Q36139222Identification of a B subunit gene promoter in the Shiga toxin operon of Shigella dysenteriae 1
Q36124364Identification of the Shiga toxin A-subunit residues required for holotoxin assembly
Q35620166Investigation of ribosome binding by the Shiga toxin A1 subunit, using competition and site-directed mutagenesis
Q54323381Large-scale preparation of Shiga toxin 2 in Escherichia coli for toxoid vaccine antigen production.
Q36973773Mapping the minimal contiguous gene segment that encodes functionally active Shiga-like toxin II
Q36103964Minimum domain of the Shiga toxin A subunit required for enzymatic activity
Q38303627Nasal immunization with E. coli verotoxin 1 (VT1)-B subunit and a nontoxic mutant of cholera toxin elicits serum neutralizing antibodies
Q33377371Protection against Shiga toxin-producing Escherichia coli infection by transcutaneous immunization with Shiga toxin subunit B
Q34667008Shiga toxin of enterohemorrhagic Escherichia coli type O157:H7 promotes intestinal colonization.
Q33399096The CXCR4/CXCR7/SDF-1 pathway contributes to the pathogenesis of Shiga toxin-associated hemolytic uremic syndrome in humans and mice
Q54648744The role of tyrosine-114 in the enzymatic activity of the Shiga-like toxin I A-chain.

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