Role of glutamic acid 177 of the ricin toxin A chain in enzymatic inactivation of ribosomes

scientific article published on November 1989

Role of glutamic acid 177 of the ricin toxin A chain in enzymatic inactivation of ribosomes is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/MCB.9.11.5012
P932PMC publication ID363653
P698PubMed publication ID2689871

P2093author name stringAlexander A
Welsh P
Schlossman D
Frankel A
Robertus J
Withers D
P2860cites workDNA sequencing with chain-terminating inhibitorsQ22066207
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Evidence that glutamic acid 167 is an active-site residue of Shiga-like toxin IQ24651553
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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Q25938983
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingQ25938984
Sequences That Regulate the Divergent GAL1-GAL10 Promoter in Saccharomyces cerevisiaeQ29547797
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Interaction of elongation factors EF-G and EF-Tu with a conserved loop in 23S RNA.Q34039940
Nucleotide sequence of the Shiga-like toxin genes of Escherichia coliQ34633814
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Interaction of the bovine papillomavirus type 1 E2 transcriptional control protein with the viral enhancer: purification of the DNA-binding domain and analysis of its contact points with DNAQ36868550
Functional domains of the yeast regulatory protein GAL4.Q37397679
Use of gene fusions and protein-protein interaction in the isolation of a biologically active regulatory protein: the replication initiator protein of plasmid R6K.Q37511258
Rapid purification of a cloned gene product by genetic fusion and site-specific proteolysisQ37560479
Genomic cloning and characterization of a ricin gene from Ricinus communisQ40472529
Selection and characterization of ricin toxin A-chain mutations in Saccharomyces cerevisiaeQ40646196
Ribosome-inhibiting proteins, retroviral reverse transcriptases, and RNase H share common structural elementsQ45244947
Expression of soluble and fully functional ricin A chain in Escherichia coli is temperature-sensitiveQ46272352
Interaction of Cibacron blue F3GA and polynucleotides with ricin A-chain, 60 S ribosomal subunit-inactivating protein.Q50901511
Chemical structure of a modification of the Escherichia coli ribonucleic acid polymerase alpha polypeptides induced by bacteriophage T4 infection.Q54333485
The mechanism of action of ricin and related toxic lectins on eukaryotic ribosomes. The site and the characteristics of the modification in 28 S ribosomal RNA caused by the toxins.Q54408348
A phase I study of T101-ricin A chain immunotoxin in refractory chronic lymphocytic leukemiaQ68371389
Expression of ricin A chain in Escherichia coliQ68957425
The three-dimensional structure of ricin at 2.8 AQ68962681
Treatment of abrin and ricin with -mercaptoethanol opposite effects on their toxicity in mice and their ability to inhibit protein synthesis in a cell-free systemQ69403426
Involvement of arginine residues in inhibition of protein synthesis by ricin A-chainQ69568689
Entry of lethal doses of abrin, ricin and modeccin into the cytosol of HeLa cellsQ71157907
P433issue11
P407language of work or nameEnglishQ1860
P304page(s)5012-5021
P577publication date1989-11-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleRole of glutamic acid 177 of the ricin toxin A chain in enzymatic inactivation of ribosomes
P478volume9

Reverse relations

cites work (P2860)
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Q35645525Analysis of the contribution of an amphiphilic alpha-helix to the structure and to the function of ricin A chain
Q37234010Arginine residues on the opposite side of the active site stimulate the catalysis of ribosome depurination by ricin A chain by interacting with the P-protein stalk
Q34662665Cloning and expression of three abrin A-chains and their mutants derived by site-specific mutagenesis in Escherichia coli
Q37424949Conserved Arginines at the P-Protein Stalk Binding Site and the Active Site Are Critical for Ribosome Interactions of Shiga Toxins but Do Not Contribute to Differences in the Affinity of the A1 Subunits for the Ribosome
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Q43733544Electrostatic effects on the free-energy balance in folding a ribosome-inactivating protein
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