The role of tyrosine-114 in the enzymatic activity of the Shiga-like toxin I A-chain.

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The role of tyrosine-114 in the enzymatic activity of the Shiga-like toxin I A-chain. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/BF00284701
P698PubMed publication ID8246901

P2093author name stringC J Hovde
P R Austin
R L Deresiewicz
P2860cites workEvidence that glutamic acid 167 is an active-site residue of Shiga-like toxin IQ24651553
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Nucleotide sequence of the Shiga-like toxin genes of Escherichia coliQ34633814
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Pathogenesis of Shigella diarrhea. IX. Simplified high yield purification of Shigella toxin and characterization of subunit composition and function by the use of subunit-specific monoclonal and polyclonal antibodies.Q36349737
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Importance of arginine at position 170 of the A subunit of Vero toxin 1 produced by enterohemorrhagic Escherichia coli for toxin activity.Q38334562
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Purification of an Escherichia coli serogroup O157:H7 verotoxin and its detection in North American hemorrhagic colitis isolates.Q40200609
Selection and characterization of ricin toxin A-chain mutations in Saccharomyces cerevisiaeQ40646196
Role of arginine 180 and glutamic acid 177 of ricin toxin A chain in enzymatic inactivation of ribosomesQ40647546
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Mutations affecting the activity of the Shiga-like toxin I A-chainQ44645523
Structure of ricin A-chain at 2.5 A.Q45233913
Ribosome-inhibiting proteins, retroviral reverse transcriptases, and RNase H share common structural elementsQ45244947
Subunit structure of Shigella cytotoxin.Q50938170
The mechanism of action of ricin and related toxic lectins on eukaryotic ribosomes. The site and the characteristics of the modification in 28 S ribosomal RNA caused by the toxins.Q54408348
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The cytotoxic activity of Shigella toxin. Evidence for catalytic inactivation of the 60 S ribosomal subunitQ71855282
P433issue3-4
P304page(s)467-473
P577publication date1993-11-01
P1433published inMolecular Genetics and GenomicsQ15753424
P1476titleThe role of tyrosine-114 in the enzymatic activity of the Shiga-like toxin I A-chain.
P478volume241

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cites work (P2860)
Q33529309An evolved ribosome-inactivating protein targets and kills human melanoma cells in vitro and in vivo
Q33767533Disruption of an internal membrane-spanning region in Shiga toxin 1 reduces cytotoxicity
Q26858938Do the A subunits contribute to the differences in the toxicity of Shiga toxin 1 and Shiga toxin 2?
Q82754354Enhanced immunogenicity of a novel Stx2Am-Stx1B fusion protein in a mice model of enterohemorrhagic Escherichia coli O157:H7 infection
Q35779632Evidence that the A2 fragment of Shiga-like toxin type I is required for holotoxin integrity
Q48220960Genetic and Immunological Analysis of a Novel Variant of Shiga Toxin 1 from Bovine Escherichia coli Strains and Development of Bead‐ELISA to Detect the Variant Toxin
Q34663367Identification of amino acids critical for the cytotoxicity of Shiga toxin 1 and 2 in Saccharomyces cerevisiae
Q74320355Shiga-like toxin-VEGF fusion proteins are selectively cytotoxic to endothelial cells overexpressing VEGFR-2

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