scholarly article | Q13442814 |
review article | Q7318358 |
P2093 | author name string | Debaleena Basu | |
Nilgun Tumer | |||
P2860 | cites work | Shiga toxin receptor Gb3Cer/CD77: tumor-association and promising therapeutic target in pancreas and colon cancer | Q21090050 |
Diarrheagenic Escherichia coli | Q24533466 | ||
Foodborne illness acquired in the United States--major pathogens | Q24603736 | ||
The C-terminal fragment of the ribosomal P protein complexed to trichosanthin reveals the interaction between the ribosome-inactivating protein and the ribosome | Q24642956 | ||
Two toxin-converting phages from Escherichia coli O157:H7 strain 933 encode antigenically distinct toxins with similar biologic activities | Q24646436 | ||
Evidence that glutamic acid 167 is an active-site residue of Shiga-like toxin I | Q24651553 | ||
Pokeweed antiviral protein, a ribosome inactivating protein: activity, inhibition and prospects | Q26822931 | ||
Crystal structure of the cell-binding B oligomer of verotoxin-1 from E. coli | Q27644365 | ||
Differential cytotoxic actions of Shiga toxin 1 and Shiga toxin 2 on microvascular and macrovascular endothelial cells. | Q54374441 | ||
Receptor affinity, stability and binding mode of Shiga toxins are determinants of toxicity. | Q54440673 | ||
Specific Interaction of Escherichia coli 0157:H7-Derived Shiga-like Toxin II with Human Renal Endothelial Cells | Q54601011 | ||
The role of tyrosine-114 in the enzymatic activity of the Shiga-like toxin I A-chain. | Q54648744 | ||
Nucleotide sequence analysis and comparison of the structural genes for Shiga-like toxin I and Shiga-like toxin II encoded by bacteriophages fromEscherichia coli933 | Q57563895 | ||
Preparation of VT1 and VT2 hybrid toxins from their purified dissociated subunits. Evidence for B subunit modulation of a subunit function | Q67913265 | ||
Globotetraosylceramide is recognized by the pig edema disease toxin | Q69517260 | ||
Isolation and some properties of A and B subunits of Vero toxin 2 and in vitro formation of hybrid toxins between subunits of Vero toxin 1 and Vero toxin 2 from Escherichia coli O157:H7 | Q70240833 | ||
Ricin A chain can be chemically cross-linked to the mammalian ribosomal proteins L9 and L10e | Q72259927 | ||
Oligomerization properties of the acidic ribosomal P-proteins from Saccharomyces cerevisiae: effect of P1A protein phosphorylation on the formation of the P1A-P2B hetero-complex | Q73300847 | ||
The RNA-N-glycosidase activity of Shiga-like toxin I: kinetic parameters of the native and activated toxin | Q73952496 | ||
Interaction of elongation factor eEF-2 with ribosomal P proteins | Q77773230 | ||
The C-terminal end of P proteins mediates ribosome inactivation by trichosanthin but does not affect the pokeweed antiviral protein activity | Q80725838 | ||
Structural properties of the human acidic ribosomal P proteins forming the P1-P2 heterocomplex | Q81555060 | ||
Yeast ribosomal P0 protein has two separate binding sites for P1/P2 proteins | Q83013729 | ||
Pokeweed antiviral protein accesses ribosomes by binding to L3. | Q54107189 | ||
Solution structure of human P1*P2 heterodimer provides insights into the role of eukaryotic stalk in recruiting the ribosome-inactivating protein trichosanthin to the ribosome | Q27679227 | ||
The Crystal Structure of Shiga Toxin Type 2 with Bound Disaccharide Guides the Design of a Heterobifunctional Toxin Inhibitor | Q27680604 | ||
Crystal structure of the holotoxino from Shigella dysenteriae at 2.5 Å resolution | Q27729840 | ||
Structure of the shiga-like toxin I B-pentamer complexed with an analogue of its receptor Gb3 | Q27748877 | ||
The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae | Q27936301 | ||
Pokeweed antiviral protein: its cytotoxicity mechanism and applications in plant disease resistance | Q28081661 | ||
Trichosanthin interacts with acidic ribosomal proteins P0 and P1 and mitotic checkpoint protein MAD2B | Q28207582 | ||
Differential tissue targeting and pathogenesis of verotoxins 1 and 2 in the mouse animal model | Q33343579 | ||
Response to Shiga toxin 1 and 2 in a baboon model of hemolytic uremic syndrome | Q33346480 | ||
Hemolytic uremic syndrome; pathogenesis, treatment, and outcome | Q33365631 | ||
Enterohaemorrhagic Escherichia coli in human medicine | Q33368999 | ||
Variation in virulence among clades of Escherichia coli O157:H7 associated with disease outbreaks | Q33378926 | ||
Distinct physiologic and inflammatory responses elicited in baboons after challenge with Shiga toxin type 1 or 2 from enterohemorrhagic Escherichia coli | Q33388849 | ||
Epidemic profile of Shiga-toxin-producing Escherichia coli O104:H4 outbreak in Germany | Q33395886 | ||
Characterisation of the Escherichia coli strain associated with an outbreak of haemolytic uraemic syndrome in Germany, 2011: a microbiological study | Q33395933 | ||
The enemy within us: lessons from the 2011 European Escherichia coli O104:H4 outbreak | Q33402995 | ||
Shiga toxins and the pathophysiology of hemolytic uremic syndrome in humans and animals | Q33404640 | ||
Distinct renal pathology and a chemotactic phenotype after enterohemorrhagic Escherichia coli shiga toxins in non-human primate models of hemolytic uremic syndrome | Q33405827 | ||
Identification of TLR4 as the receptor that recognizes Shiga toxins in human neutrophils | Q33410575 | ||
Overview and Historical Perspectives | Q33419782 | ||
Hemolytic-uremic syndrome and enterohemorrhagic Escherichia coli | Q33492019 | ||
Associations between virulence factors of Shiga toxin-producing Escherichia coli and disease in humans | Q33505189 | ||
Biophysical properties of the eukaryotic ribosomal stalk | Q33522691 | ||
Comparison of the relative toxicities of Shiga-like toxins type I and type II for mice | Q33605233 | ||
Development of a quantitative RT-PCR assay to examine the kinetics of ribosome depurination by ribosome inactivating proteins using Saccharomyces cerevisiae as a model | Q33753680 | ||
Comparison of binding platforms yields insights into receptor binding differences between shiga toxins 1 and 2 | Q33801217 | ||
Site of action of a Vero toxin (VT2) from Escherichia coli O157:H7 and of Shiga toxin on eukaryotic ribosomes. RNA N-glycosidase activity of the toxins. | Q34049372 | ||
Charged and hydrophobic surfaces on the a chain of shiga-like toxin 1 recognize the C-terminal domain of ribosomal stalk proteins | Q34166278 | ||
The RNA N-glycosidase activity of ricin A-chain. The characteristics of the enzymatic activity of ricin A-chain with ribosomes and with rRNA. | Q34172482 | ||
Human intestinal tissue and cultured colonic cells contain globotriaosylceramide synthase mRNA and the alternate Shiga toxin receptor globotetraosylceramide. | Q34290908 | ||
Shiga toxins | Q34298388 | ||
Pentameric organization of the ribosomal stalk accelerates recruitment of ricin a chain to the ribosome for depurination | Q34438778 | ||
Nucleotide sequence of the Shiga-like toxin genes of Escherichia coli | Q34633814 | ||
Structure and Dynamics of Ribosomal Protein L12: An Ensemble Model Based on SAXS and NMR Relaxation | Q40625926 | ||
Role of verotoxin receptors in pathogenesis | Q41052833 | ||
The large ribosomal subunit stalk as a regulatory element of the eukaryotic translational machinery. | Q41096585 | ||
Structural basis for the function of the ribosomal L7/12 stalk in factor binding and GTPase activation | Q41627064 | ||
Interaction between trichosanthin, a ribosome-inactivating protein, and the ribosomal stalk protein P2 by chemical shift perturbation and mutagenesis analyses | Q41934174 | ||
A mode of assembly of P0, P1, and P2 proteins at the GTPase-associated center in animal ribosome: in vitro analyses with P0 truncation mutants | Q42039672 | ||
The catalytic subunit of shiga-like toxin 1 interacts with ribosomal stalk proteins and is inhibited by their conserved C-terminal domain | Q42648942 | ||
Shiga toxin 1 and ricin A chain bind to human polymorphonuclear leucocytes through a common receptor | Q42920438 | ||
Three binding sites for stalk protein dimers are generally present in ribosomes from archaeal organism | Q43023215 | ||
Atomic mutagenesis reveals A2660 of 23S ribosomal RNA as key to EF-G GTPase activation | Q43116255 | ||
Kinetic analysis of binding between Shiga toxin and receptor glycolipid Gb3Cer by surface plasmon resonance | Q43738152 | ||
Convergent evolution led ribosome inactivating proteins to interact with ribosomal stalk | Q44572057 | ||
Structure of shiga toxin type 2 (Stx2) from Escherichia coli O157:H7. | Q44838252 | ||
RIBOSOME-INACTIVATING PROTEINS: A Plant Perspective | Q44875240 | ||
The primary structure of rat ribosomal proteins P0, P1, and P2 and a proposal for a uniform nomenclature for mammalian and yeast ribosomal proteins | Q48220438 | ||
Promiscuous Shiga toxin 2e and its intimate relationship to Forssman. | Q48691738 | ||
Furin-induced cleavage and activation of Shiga toxin | Q49165095 | ||
Identification of amino acids critical for the cytotoxicity of Shiga toxin 1 and 2 in Saccharomyces cerevisiae | Q34663367 | ||
Shiga toxin subtypes display dramatic differences in potency | Q34739913 | ||
Revising the taxonomic distribution, origin and evolution of ribosome inactivating protein genes | Q34988582 | ||
Acute renal tubular necrosis and death of mice orally infected with Escherichia coli strains that produce Shiga-like toxin type II | Q35109009 | ||
Comparisons of native Shiga toxins (Stxs) type 1 and 2 with chimeric toxins indicate that the source of the binding subunit dictates degree of toxicity | Q35132357 | ||
The puzzling lateral flexible stalk of the ribosome | Q35179486 | ||
Glycolipid binding preferences of Shiga toxin variants | Q35199053 | ||
Shiga toxin 1 is more dependent on the P proteins of the ribosomal stalk for depurination activity than Shiga toxin 2 | Q35501790 | ||
Investigation of ribosome binding by the Shiga toxin A1 subunit, using competition and site-directed mutagenesis | Q35620166 | ||
Antiviral activity of ribosome inactivating proteins in medicine | Q35794009 | ||
Ribosome-inactivating proteins | Q35859613 | ||
Functional role of the sarcin-ricin loop of the 23S rRNA in the elongation cycle of protein synthesis | Q35946837 | ||
Delivery into cells: lessons learned from plant and bacterial toxins | Q36091291 | ||
Mutational analysis of the Shiga toxin and Shiga-like toxin II enzymatic subunits | Q36165342 | ||
Multicenter evaluation of a sequence-based protocol for subtyping Shiga toxins and standardizing Stx nomenclature | Q36172302 | ||
Cloning and sequencing of the genes for Shiga toxin from Shigella dysenteriae type 1. | Q36194407 | ||
The P1/P2 proteins of the human ribosomal stalk are required for ribosome binding and depurination by ricin in human cells | Q36296036 | ||
Binding of adenine to Stx2, the protein toxin from Escherichia coli O157:H7. | Q36459565 | ||
Targeting ricin to the ribosome | Q36901746 | ||
Comparison of the glycolipid receptor specificities of Shiga-like toxin type II and Shiga-like toxin type II variants | Q36977977 | ||
In vivo formation of hybrid toxins comprising Shiga toxin and the Shiga-like toxins and role of the B subunit in localization and cytotoxic activity | Q37006892 | ||
The ribosomal stalk is required for ribosome binding, depurination of the rRNA and cytotoxicity of ricin A chain in Saccharomyces cerevisiae | Q37088333 | ||
A two-step binding model proposed for the electrostatic interactions of ricin a chain with ribosomes. | Q37180842 | ||
Arginine residues on the opposite side of the active site stimulate the catalysis of ribosome depurination by ricin A chain by interacting with the P-protein stalk | Q37234010 | ||
Monoclonal antibody 11E10, which neutralizes shiga toxin type 2 (Stx2), recognizes three regions on the Stx2 A subunit, blocks the enzymatic action of the toxin in vitro, and alters the overall cellular distribution of the toxin. | Q37256478 | ||
Shiga toxins--from cell biology to biomedical applications | Q37659792 | ||
RNA toxins: mediators of stress adaptation and pathogen defense | Q37910091 | ||
Facing glycosphingolipid-Shiga toxin interaction: dire straits for endothelial cells of the human vasculature | Q38024274 | ||
Ribosome-inactivating proteins: from toxins to useful proteins | Q38086669 | ||
Ribosome-inactivating proteins: potent poisons and molecular tools | Q38144759 | ||
Free energy determinants of binding the rRNA substrate and small ligands to ricin A-chain | Q38329838 | ||
Importance of arginine at position 170 of the A subunit of Vero toxin 1 produced by enterohemorrhagic Escherichia coli for toxin activity. | Q38334562 | ||
Detecting ricin: sensitive luminescent assay for ricin A-chain ribosome depurination kinetics | Q38355109 | ||
Structures of eukaryotic ribosomal stalk proteins and its complex with trichosanthin, and their implications in recruiting ribosome-inactivating proteins to the ribosomes | Q38365820 | ||
Tumor-specific targeting of pancreatic cancer with Shiga toxin B-subunit | Q39501025 | ||
P275 | copyright license | Creative Commons Attribution | Q6905323 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 5 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | enzyme | Q8047 |
protein subunit | Q899781 | ||
bacterial protein | Q64923821 | ||
P304 | page(s) | 1467-85 | |
P577 | publication date | 2015-04-29 | |
P1433 | published in | Toxins | Q15724569 |
P1476 | title | Do the A subunits contribute to the differences in the toxicity of Shiga toxin 1 and Shiga toxin 2? | |
P478 | volume | 7 |
Q43196106 | Different roles of the C-terminal end of Stx1A and Stx2A for AB5 complex integrity and retrograde transport of Stx in HeLa cells |
Q61697249 | Enterohemorrhagic (Shiga Toxin-Producing) Escherichia coli |
Q42695863 | Enterotoxins: Microbial Proteins and Host Cell Dysregulation |
Q40774571 | Identification of Shiga toxin-producing (STEC) and enteropathogenic (EPEC) Escherichia coli in diarrhoeic calves and comparative genomics of O5 bovine and human STEC. |
Q42251450 | In silico analysis of Shiga toxins (Stxs) to identify new potential vaccine targets for Shiga toxin-producing Escherichia coli. |
Q33426867 | The A1 Subunit of Shiga Toxin 2 Has Higher Affinity for Ribosomes and Higher Catalytic Activity than the A1 Subunit of Shiga Toxin 1. |
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