| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2012PLoSO...731191M |
| P356 | DOI | 10.1371/JOURNAL.PONE.0031191 |
| P932 | PMC publication ID | 3280276 |
| P698 | PubMed publication ID | 22355345 |
| P5875 | ResearchGate publication ID | 221852133 |
| P2093 | author name string | Gang Chen | |
| Sachdev S Sidhu | |||
| Nick Jarvik | |||
| Jean Gariépy | |||
| Andrew J McCluskey | |||
| Eleonora Bolewska-Pedyczak | |||
| P2860 | cites work | Identification of the carbohydrate receptor for Shiga toxin produced by Shigella dysenteriae type 1. | Q38349693 |
| Pathogenesis of shigella diarrhea. XI. Isolation of a shigella toxin-binding glycolipid from rabbit jejunum and HeLa cells and its identification as globotriaosylceramide | Q38350915 | ||
| Detecting ricin: sensitive luminescent assay for ricin A-chain ribosome depurination kinetics | Q38355109 | ||
| The epidemiologic, clinical, and microbiologic features of hemorrhagic colitis | Q39683467 | ||
| Inhibition by ricin of protein synthesis in vitro. Inhibition of the binding of elongation factor 2 and of adenosine diphosphate-ribosylated elongation factor 2 to ribosomes | Q39940869 | ||
| Surfing on a retrograde wave: how does Shiga toxin reach the endoplasmic reticulum? | Q40847412 | ||
| Accumulating evidence suggests that several AB-toxins subvert the endoplasmic reticulum-associated protein degradation pathway to enter target cells | Q41614148 | ||
| Interaction of the G' domain of elongation factor G and the C-terminal domain of ribosomal protein L7/L12 during translocation as revealed by cryo-EM. | Q41626615 | ||
| A rapid and universal tandem-purification strategy for recombinant proteins | Q41910068 | ||
| Interaction between trichosanthin, a ribosome-inactivating protein, and the ribosomal stalk protein P2 by chemical shift perturbation and mutagenesis analyses | Q41934174 | ||
| The N-terminal regions of eukaryotic acidic phosphoproteins P1 and P2 are crucial for heterodimerization and assembly into the ribosomal GTPase-associated center | Q42033917 | ||
| A mode of assembly of P0, P1, and P2 proteins at the GTPase-associated center in animal ribosome: in vitro analyses with P0 truncation mutants | Q42039672 | ||
| Evidence for the importance of electrostatics in the function of two distinct families of ribosome inactivating toxins | Q42413458 | ||
| The catalytic subunit of shiga-like toxin 1 interacts with ribosomal stalk proteins and is inhibited by their conserved C-terminal domain | Q42648942 | ||
| Rare E. coli strain races through Europe; high rate of kidney failure reported | Q43610429 | ||
| Structural characterization of yeast acidic ribosomal P proteins forming the P1A-P2B heterocomplex | Q44373363 | ||
| Evidence that the G2661 region of 23S rRNA is located at the ribosomal binding sites of both elongation factors. | Q45981139 | ||
| Furin-induced cleavage and activation of Shiga toxin | Q49165095 | ||
| The C-terminal fragment of the ribosomal P protein complexed to trichosanthin reveals the interaction between the ribosome-inactivating protein and the ribosome | Q24642956 | ||
| Evidence that glutamic acid 167 is an active-site residue of Shiga-like toxin I | Q24651553 | ||
| Solution structure of an active mutant of maize ribosome-inactivating protein (MOD) and its interaction with the ribosomal stalk protein P2 | Q27658115 | ||
| Crystal structure of the holotoxino from Shigella dysenteriae at 2.5 Å resolution | Q27729840 | ||
| A novel genetic system to detect protein-protein interactions | Q27860915 | ||
| Characterization of the 26S rRNA-binding domain in Saccharomyces cerevisiae ribosomal stalk phosphoprotein P0. | Q27935747 | ||
| Analysis of the protein-protein interactions between the human acidic ribosomal P-proteins: evaluation by the two hybrid system | Q28138456 | ||
| Trichosanthin interacts with acidic ribosomal proteins P0 and P1 and mitotic checkpoint protein MAD2B | Q28207582 | ||
| Small-molecule inhibitor leads of ribosome-inactivating proteins developed using the doorstop approach | Q28477494 | ||
| Epidemic profile of Shiga-toxin-producing Escherichia coli O104:H4 outbreak in Germany | Q33395886 | ||
| Identification of new classes of ricin toxin inhibitors by virtual screening | Q33584442 | ||
| Interaction of elongation factors EF-G and EF-Tu with a conserved loop in 23S RNA. | Q34039940 | ||
| Site of action of a Vero toxin (VT2) from Escherichia coli O157:H7 and of Shiga toxin on eukaryotic ribosomes. RNA N-glycosidase activity of the toxins. | Q34049372 | ||
| The RNA N-glycosidase activity of ricin A-chain. The characteristics of the enzymatic activity of ricin A-chain with ribosomes and with rRNA. | Q34172482 | ||
| Pentameric organization of the ribosomal stalk accelerates recruitment of ricin a chain to the ribosome for depurination | Q34438778 | ||
| Identification of amino acids critical for the cytotoxicity of Shiga toxin 1 and 2 in Saccharomyces cerevisiae | Q34663367 | ||
| The electrostatic character of the ribosomal surface enables extraordinarily rapid target location by ribotoxins | Q35741993 | ||
| Infection by verocytotoxin-producing Escherichia coli | Q36634680 | ||
| The ribosomal stalk is required for ribosome binding, depurination of the rRNA and cytotoxicity of ricin A chain in Saccharomyces cerevisiae | Q37088333 | ||
| A two-step binding model proposed for the electrostatic interactions of ricin a chain with ribosomes. | Q37180842 | ||
| Dissection of the high rate constant for the binding of a ribotoxin to the ribosome. | Q37182759 | ||
| Identification and biochemical characterization of small-molecule inhibitors of Clostridium botulinum neurotoxin serotype A | Q37274652 | ||
| A role for the protease-sensitive loop region of Shiga-like toxin 1 in the retrotranslocation of its A1 domain from the endoplasmic reticulum lumen | Q38328315 | ||
| The acidic protein binding site is partially hidden in the free Saccharomyces cerevisiae ribosomal stalk protein P0. | Q38328492 | ||
| Importance of arginine at position 170 of the A subunit of Vero toxin 1 produced by enterohemorrhagic Escherichia coli for toxin activity. | Q38334562 | ||
| Purification and crystallization of Shiga toxin from Shigella dysenteriae. | Q50781159 | ||
| The mechanism of action of ricin and related toxic lectins on eukaryotic ribosomes. The site and the characteristics of the modification in 28 S ribosomal RNA caused by the toxins. | Q54408348 | ||
| Membrane cytosolic translocation of verotoxin A1 subunit in target cells. | Q54737751 | ||
| Glycolipid binding of purified and recombinant Escherichia coli produced verotoxin in vitro. | Q54764104 | ||
| Hemolytic Uremic Syndrome | Q56336649 | ||
| Structural Characterization of the Ribosomal P1A−P2B Protein Dimer by Small-Angle X-ray Scattering and NMR Spectroscopy† | Q57090972 | ||
| Nucleotide sequence analysis and comparison of the structural genes for Shiga-like toxin I and Shiga-like toxin II encoded by bacteriophages fromEscherichia coli933 | Q57563895 | ||
| The RNA N-glycosidase activity of ricin A-chain | Q68033208 | ||
| Pivotal role of the P1 N-terminal domain in the assembly of the mammalian ribosomal stalk and in the proteosynthetic activity | Q73684840 | ||
| The RNA-N-glycosidase activity of Shiga-like toxin I: kinetic parameters of the native and activated toxin | Q73952496 | ||
| Interaction of elongation factor eEF-2 with ribosomal P proteins | Q77773230 | ||
| Proteolytic cleavage of the A subunit is essential for maximal cytotoxicity of Escherichia coli O157:H7 Shiga-like toxin-1 | Q77905375 | ||
| The ribosomal stalk binds to translation factors IF2, EF-Tu, EF-G and RF3 via a conserved region of the L12 C-terminal domain | Q79311756 | ||
| Exploring "one-shot" kinetics and small molecule analysis using the ProteOn XPR36 array biosensor | Q80234854 | ||
| The C-terminal end of P proteins mediates ribosome inactivation by trichosanthin but does not affect the pokeweed antiviral protein activity | Q80725838 | ||
| Yeast ribosomal P0 protein has two separate binding sites for P1/P2 proteins | Q83013729 | ||
| Infectious diseases. As E. coli outbreak recedes, new questions come to the fore | Q84481447 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 2 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | hydrophobicity | Q41854968 |
| P304 | page(s) | e31191 | |
| P577 | publication date | 2012-02-15 | |
| P1433 | published in | PLOS One | Q564954 |
| P1476 | title | Charged and hydrophobic surfaces on the a chain of shiga-like toxin 1 recognize the C-terminal domain of ribosomal stalk proteins | |
| P478 | volume | 7 |
| Q37234010 | Arginine residues on the opposite side of the active site stimulate the catalysis of ribosome depurination by ricin A chain by interacting with the P-protein stalk |
| Q37424949 | Conserved Arginines at the P-Protein Stalk Binding Site and the Active Site Are Critical for Ribosome Interactions of Shiga Toxins but Do Not Contribute to Differences in the Affinity of the A1 Subunits for the Ribosome |
| Q37378931 | Crystal Structure of Ribosome-Inactivating Protein Ricin A Chain in Complex with the C-Terminal Peptide of the Ribosomal Stalk Protein P2. |
| Q33612042 | Differences in Ribosome Binding and Sarcin/Ricin Loop Depurination by Shiga and Ricin Holotoxins |
| Q26858938 | Do the A subunits contribute to the differences in the toxicity of Shiga toxin 1 and Shiga toxin 2? |
| Q39206729 | Extensive Evolution of Cereal Ribosome-Inactivating Proteins Translates into Unique Structural Features, Activation Mechanisms, and Physiological Roles |
| Q38024274 | Facing glycosphingolipid-Shiga toxin interaction: dire straits for endothelial cells of the human vasculature |
| Q64930460 | How Ricin Damages the Ribosome. |
| Q33911820 | Human ribosomal P1-P2 heterodimer represents an optimal docking site for ricin A chain with a prominent role for P1 C-terminus |
| Q90240074 | Leucine 232 and hydrophobic residues at the ribosomal P stalk binding site are critical for biological activity of ricin |
| Q34515656 | Maize ribosome-inactivating protein uses Lys158-lys161 to interact with ribosomal protein P2 and the strength of interaction is correlated to the biological activities |
| Q58742640 | Peptide Mimics of the Ribosomal P Stalk Inhibit the Activity of Ricin A Chain by Preventing Ribosome Binding |
| Q37660963 | Ricin uses arginine 235 as an anchor residue to bind to P-proteins of the ribosomal stalk. |
| Q30009128 | Selection of recombinant anti-SH3 domain antibodies by high-throughput phage display |
| Q27021676 | Shiga Toxin (Stx) Classification, Structure, and Function |
| Q58734587 | Structural and Functional Investigation and Pharmacological Mechanism of Trichosanthin, a Type 1 Ribosome-Inactivating Protein |
| Q38365820 | Structures of eukaryotic ribosomal stalk proteins and its complex with trichosanthin, and their implications in recruiting ribosome-inactivating proteins to the ribosomes |
| Q36901746 | Targeting ricin to the ribosome |
| Q33426867 | The A1 Subunit of Shiga Toxin 2 Has Higher Affinity for Ribosomes and Higher Catalytic Activity than the A1 Subunit of Shiga Toxin 1. |
| Q36296036 | The P1/P2 proteins of the human ribosomal stalk are required for ribosome binding and depurination by ricin in human cells |
| Q38745809 | Toxicity of ricin A chain is reduced in mammalian cells by inhibiting its interaction with the ribosome |
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