The effect of glucosamine and/or chondroitin sulfate on the progression of knee osteoarthritis: a report from the glucosamine/chondroitin arthritis intervention trial

scientific article

The effect of glucosamine and/or chondroitin sulfate on the progression of knee osteoarthritis: a report from the glucosamine/chondroitin arthritis intervention trial is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/ART.23973
P3181OpenCitations bibliographic resource ID3365288
P932PMC publication ID2836125
P698PubMed publication ID18821708
P5875ResearchGate publication ID23288047

P50authorNora G. SingerQ37830320
Chester V. OddisQ114404222
P2093author name stringClifton O Bingham
Nancy E Lane
Dorothy D Dunlop
Daniel O Clegg
Allen D Sawitzke
Fred Wolfe
Domenic J Reda
Daniel E Furst
Helen Shi
Roland W Moskowitz
Jeffrey Lisse
David Silver
H James Williams
John D Bradley
Crystal L Harris
Christopher G Jackson
Martha F Finco
P2860cites workEULAR Recommendations 2003: an evidence based approach to the management of knee osteoarthritis: Report of a Task Force of the Standing Committee for International Clinical Studies Including Therapeutic Trials (ESCISIT)Q24674132
Glucosamine and chondroitin for treatment of osteoarthritis: a systematic quality assessment and meta-analysisQ28374250
Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part IIQ28396036
Radiological assessment of osteo-arthrosisQ29614927
OsiriX: an open-source software for navigating in multidimensional DICOM imagesQ31126270
Long-term effects of glucosamine sulphate on osteoarthritis progression: a randomised, placebo-controlled clinical trialQ32050561
A 2 yr longitudinal radiographic study examining the effect of a bisphosphonate (risedronate) upon subchondral bone loss in osteoarthritic knee patientsQ33249982
Osteoarthritis: new insights. Part 1: the disease and its risk factors.Q33921631
Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritisQ33993736
Structural and symptomatic efficacy of glucosamine and chondroitin in knee osteoarthritis: a comprehensive meta-analysisQ34214244
Glucosamine sulfate use and delay of progression of knee osteoarthritis: a 3-year, randomized, placebo-controlled, double-blind studyQ34528067
Meta-analysis: chondroitin for osteoarthritis of the knee or hip.Q34619761
Which is the best radiographic protocol for a clinical trial of a structure modifying drug in patients with knee osteoarthritis?Q34685925
Comparison of quantitative and semiquantitative indicators of joint space narrowing in subjects with knee osteoarthritisQ35636580
Review of the anatomical and radiological differences between fluoroscopic and non-fluoroscopic positioning of osteoarthritic kneesQ36511560
Risedronate decreases biochemical markers of cartilage degradation but does not decrease symptoms or slow radiographic progression in patients with medial compartment osteoarthritis of the knee: results of the two-year multinational knee osteoarthriQ39344079
Measurement of radiographic joint space width in the tibiofemoral compartment of the osteoarthritic knee: comparison of standing anteroposterior and Lyon schuss viewsQ39641539
Detection of radiographic joint space narrowing in subjects with knee osteoarthritis: longitudinal comparison of the metatarsophalangeal and semiflexed anteroposterior viewsQ39641542
Pitfalls in the accurate measurement of joint space narrowing in semiflexed, anteroposterior radiographic imaging of the kneeQ39693235
Effect of non-steroidal anti-inflammatory drugs on the course of osteoarthritisQ41277159
Early stages of osteoarthritis: the search for sensitive predictorsQ42118121
Yet more evidence that osteoarthritis is not a cartilage diseaseQ42955504
Variability in knee radiographing: implication for definition of radiological progression in medial knee osteoarthritis.Q43053545
Effect sizes for interpreting changes in health status.Q43872888
A 12-month, multicenter, prospective, open-label trial of radiographic analysis of disease progression in osteoarthritis of the knee or hip in patients receiving celecoxibQ44311938
OMERACT workshop radiography session 1.Q46453352
Radiographic methods in knee osteoarthritis: a further comparison of semiflexed (MTP), schuss-tunnel, and weight-bearing anteroposterior views for joint space narrowing and osteophytes.Q47174826
Reproducibility of the semiflexed (metatarsophalangeal) radiographic knee position and automated measurements of medial tibiofemoral joint space width in a multicenter clinical trial of knee osteoarthritis.Q48563818
Effects of oral chondroitin sulfate on the progression of knee osteoarthritis: a pilot studyQ48592216
Guidelines for testing slow acting drugs in osteoarthritis.Q50597580
Selection of knee radiographs for trials of structure-modifying drugs in patients with knee osteoarthritis: a prospective, longitudinal study of Lyon Schuss knee radiographs with the definition of adequate alignment of the medial tibial plateauQ50761045
Precision and accuracy of joint space width measurements of the medial compartment of the knee using standardized MTP semi-flexed radiographs.Q51824157
Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part I.Q55047291
Assessment of the radioanatomic positioning of the osteoarthritic knee in serial radiographs: comparison of three acquisition techniquesQ56420434
The association of meniscal pathologic changes with cartilage loss in symptomatic knee osteoarthritisQ57244856
The relationship between cartilage loss on magnetic resonance imaging and radiographic progression in men and women with knee osteoarthritisQ57244861
Comparison of naproxen and acetaminophen in a two-year study of treatment of osteoarthritis of the kneeQ72547388
Substantial superiority of semiflexed (MTP) views in knee osteoarthritis: a comparative radiographic study, without fluoroscopy, of standing extended, semiflexed (MTP), and schuss viewsQ73292593
Field test of the reproducibility of the semiflexed metatarsophalangeal view in repeated radiographic examinations of subjects with osteoarthritis of the kneeQ77567369
[Anti-arthrosis treatments: efficacy and tolerance of chondroitin sulfates (CS 4&6)]Q77693001
Chondroitins 4 and 6 sulfate in osteoarthritis of the knee: a randomized, controlled trialQ81484755
Translating osteoarthritis into numbers: the importance of alignment in knee radiography for clinical trials of structure-modifying drugsQ81726566
Comparison of fixed flexion, fluoroscopic semi-flexed and MTP radiographic methods for obtaining the minimum medial joint space width of the knee in longitudinal osteoarthritis trialsQ83309519
Efficacy of glucosamine and chondroitin for treatment of osteoarthritisQ93939295
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectknee osteoarthritisQ1777118
osteoarthritisQ62736
glucosamineQ32907954
P304page(s)3183-3191
P577publication date2008-10-01
P1433published inArthritis and RheumatismQ23929027
P1476titleThe effect of glucosamine and/or chondroitin sulfate on the progression of knee osteoarthritis: a report from the glucosamine/chondroitin arthritis intervention trial
P478volume58

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cites work (P2860)
Q3367895410mM glucosamine prevents activation of proADAMTS5 (aggrecanase-2) in transfected cells by interference with post-translational modification of furin
Q42697105A Fresh Perspective on a Familiar Problem: Examining Disparities in Knee Osteoarthritis Using a Markov Model
Q33873693A peptidyl-glucosamine derivative affects IKKalpha kinase activity in human chondrocytes
Q35770645A randomized comparative study of safety and efficacy of immediate release glucosamine HCL and glucosamine HCL sustained release formulation in the treatment of knee osteoarthritis: A proof of concept study
Q39906208Anticytokine therapy for osteoarthritis: evidence to date
Q89851444Arctigenin prevents the progression of osteoarthritis by targeting PI3K/Akt/NF-κB axis: In vitro and in vivo studies
Q90695739Association of Pharmacological Treatments With Long-term Pain Control in Patients With Knee Osteoarthritis: A Systematic Review and Meta-analysis
Q38429953COX-2-selective NSAIDs and risk of hip or knee replacements: a population-based case-control study
Q35197151Can we identify patients with high risk of osteoarthritis progression who will respond to treatment? A focus on epidemiology and phenotype of osteoarthritis
Q37960493Cartilage repair and joint preservation: medical and surgical treatment options
Q35840709Celecoxib: considerations regarding its potential disease-modifying properties in osteoarthritis
Q24186473Chondroitin for osteoarthritis
Q36059429Chondroitin sulfate in the treatment of osteoarthritis: from in vitro studies to clinical recommendations.
Q34906145Chondroitin sulphate reduces both cartilage volume loss and bone marrow lesions in knee osteoarthritis patients starting as early as 6 months after initiation of therapy: a randomised, double-blind, placebo-controlled pilot study using MRI
Q99709180Chondroprotective Actions of Selective COX-2 Inhibitors In Vivo: A Systematic Review
Q24602794Clinical efficacy and safety of glucosamine, chondroitin sulphate, their combination, celecoxib or placebo taken to treat osteoarthritis of the knee: 2-year results from GAIT
Q39539742Combined Treatment With Chondroitin Sulfate and Glucosamine Sulfate Shows No Superiority Over Placebo for Reduction of Joint Pain and Functional Impairment in Patients With Knee Osteoarthritis: A Six-Month Multicenter, Randomized, Double-Blind, Plac
Q34188301Comparative therapeutic efficacy and safety of type-II collagen (UC-II), glucosamine and chondroitin in arthritic dogs: pain evaluation by ground force plate
Q24630640Crystalline glucosamine sulfate in the management of knee osteoarthritis: efficacy, safety, and pharmacokinetic properties
Q36059344Current evidence for osteoarthritis treatments
Q47570656Current status and future prospects for disease modification in osteoarthritis.
Q43076770Dietary glucosamine under question
Q33920880Dietary supplements as disease-modifying treatments in osteoarthritis: a critical appraisal
Q30588700Disease-modifying osteoarthritis drugs: in vitro and in vivo data on the development of DMOADs under investigation.
Q50459670Effect of oral glucosamine on joint structure in individuals with chronic knee pain: a randomized, placebo-controlled clinical trial
Q35147261Effects of Glucosamine and Chondroitin Sulfate on Cartilage Metabolism in OA: Outlook on Other Nutrient Partners Especially Omega-3 Fatty Acids
Q35125975Effects of glucosamine and chondroitin supplementation on knee osteoarthritis: an analysis with marginal structural models
Q24606203Effects of glucosamine, chondroitin, or placebo in patients with osteoarthritis of hip or knee: network meta-analysis
Q34345032Efficacies of different preparations of glucosamine for the treatment of osteoarthritis: a meta-analysis of randomised, double-blind, placebo-controlled trials
Q28081360Efficacy and safety of glucosamine, diacerein, and NSAIDs in osteoarthritis knee: a systematic review and network meta-analysis
Q28278433Efficacy and safety of strontium ranelate in the treatment of knee osteoarthritis: results of a double-blind, randomised placebo-controlled trial
Q36247005Efficacy of pulsed Nd:YAG laser in the treatment of patients with knee osteoarthritis: a randomized controlled trial.
Q38758657Feline hip dysplasia: A challenge to recognise and treat.
Q30714596First-line analysis of the effects of treatment on progression of structural changes in knee osteoarthritis over 24 months: data from the osteoarthritis initiative progression cohort
Q37645550FlexPro MD, a Mixture of Krill Oil, Astaxanthin, and Hyaluronic Acid, Suppresses Lipopolysaccharide-Induced Inflammatory Cytokine Production Through Inhibition of NF-κB.
Q38090916Functional articular cartilage repair: here, near, or is the best approach not yet clear?
Q38362244Glucosamine Hydrochloride but Not Chondroitin Sulfate Prevents Cartilage Degradation and Inflammation Induced by Interleukin-1α in Bovine Cartilage Explants
Q34396147Glucosamine and chondroitin for knee osteoarthritis: a double-blind randomised placebo-controlled clinical trial evaluating single and combination regimens
Q42330053Glucosamine and chondroitin for the treatment of osteoarthritis
Q41176136Glucosamine exposure reduces proteoglycan synthesis in primary human endothelial cells in vitro
Q24630093Hepatotoxicity associated with glucosamine and chondroitin sulfate in patients with chronic liver disease
Q36949072How to define responders in osteoarthritis
Q35006721How to find nothing
Q46189093Identifying common trajectories of joint space narrowing over two years in knee osteoarthritis
Q34069452Immune modulation by chondroitin sulfate and its degraded disaccharide product in the development of an experimental model of multiple sclerosis
Q44118071Importance of pharmaceutical composition and evidence from clinical trials and pharmacological studies in determining effectiveness of chondroitin sulphate and other glycosaminoglycans: a critique
Q21195259Is there any scientific evidence for the use of glucosamine in the management of human osteoarthritis?
Q37164156Knee osteoarthritis diagnosis, treatment and associated factors of progression: part II.
Q31046250Long-Term Effects of Glucosamine and Chondroitin Sulfate on the Progression of Structural Changes in Knee Osteoarthritis: Six-Year Followup Data From the Osteoarthritis Initiative
Q34459643Management of Osteoarthritis with Avocado/Soybean Unsaponifiables.
Q35678484Methodologic issues in clinical trials for prevention or risk reduction in osteoarthritis
Q37798321Modern Management of Mild-to-Moderate Joint Pain due to Osteoarthritis: A Holistic Approach
Q38212443Modified lysozymes as novel broad spectrum natural antimicrobial agents in foods
Q37950849Non-surgical management of early knee osteoarthritis
Q38797713Non-surgical treatments for the management of early osteoarthritis.
Q38047227Nutraceuticals in the management of osteoarthritis : a critical review
Q34146992Nutraceuticals: do they represent a new era in the management of osteoarthritis? – a narrative review from the lessons taken with five products
Q26860861Nutraceuticals: potential for chondroprotection and molecular targeting of osteoarthritis
Q42683780OARSI-OMERACT initiative: defining thresholds for symptomatic severity and structural changes in disease modifying osteoarthritis drug (DMOAD) clinical trials
Q64062465Osteoarthritis- a systematic review of long-term safety implications for osteoarthritis of the knee
Q60959033Pharmacological treatment of knee osteoarthritis: Special considerations of the new German guideline
Q33845330Press releases issued by supplements industry organisations and non-industry organisations in response to publication of clinical research findings: a case-control study.
Q34157463Progress in complementary and alternative medicine research: Yale Research Symposium on Complementary and Integrative Medicine
Q37611121Quality of different chondroitin sulfate preparations in relation to their therapeutic activity
Q26799421Recommendations for an update of the 2010 European regulatory guideline on clinical investigation of medicinal products used in the treatment of osteoarthritis and reflections about related clinically relevant outcomes: expert consensus statement
Q33752290Relationship between radiographic changes and symptoms or physical examination findings in subjects with symptomatic medial knee osteoarthritis: a three-year prospective study
Q34264613Role of glucosamine in the treatment for osteoarthritis
Q39044794Suppressive effects of D-glucosamine on the 5-HT sensitive nociceptive units in the rat tooth pulpal nerve
Q41966032The Fate of Oral Glucosamine Traced by (13)C Labeling in the Dog.
Q45969369The glucosamine debate: is it better than placebo?
Q47101159Therapeutic Effects of Olive and Its Derivatives on Osteoarthritis: From Bench to Bedside
Q37964507Transglutaminase 2 as a biomarker of osteoarthritis: an update.
Q34605944Transglutaminase 2 is a marker of chondrocyte hypertrophy and osteoarthritis severity in the Hartley guinea pig model of knee OA.
Q37858371Treatment options for osteoarthritis: considerations for older adults
Q37868775What about supplements for osteoarthritis? A critical and evidenced-based review

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