review article | Q7318358 |
scholarly article | Q13442814 |
P2093 | author name string | Jörg Jerosch | |
P2860 | cites work | Osteoarthritis and nutrition. From nutraceuticals to functional foods: a systematic review of the scientific evidence | Q21195656 |
Long-term effects of chondroitins 4 and 6 sulfate on knee osteoarthritis: the study on osteoarthritis progression prevention, a two-year, randomized, double-blind, placebo-controlled trial | Q39871697 | ||
Glucosamine hydrochloride specifically inhibits COX-2 by preventing COX-2 N-glycosylation and by increasing COX-2 protein turnover in a proteasome-dependent manner | Q40106311 | ||
Sulfated glucosamine inhibits MMP-2 and MMP-9 expressions in human fibrosarcoma cells | Q40133543 | ||
Prostaglandin E2 synthesis in cartilage explants under compression: mPGES-1 is a mechanosensitive gene | Q41833959 | ||
Efficacy and safety of glucosamine sulfate versus ibuprofen in patients with knee osteoarthritis. | Q42541481 | ||
Synovial tissue inflammation in early and late osteoarthritis | Q43048512 | ||
Effect of glucosamine sulfate with or without omega-3 fatty acids in patients with osteoarthritis | Q43276199 | ||
Effect of glucosamine or chondroitin sulfate on the osteoarthritis progression: a meta-analysis | Q43546528 | ||
Crosslinking by advanced glycation end products increases the stiffness of the collagen network in human articular cartilage: a possible mechanism through which age is a risk factor for osteoarthritis | Q43873300 | ||
The effect of an oral supplement containing glucosamine, amino acids, minerals, and antioxidants on cutaneous aging: a preliminary study | Q44097220 | ||
Oral bioavailability of chondroitin sulfate (Condrosulf) and its constituents in healthy male volunteers | Q44163866 | ||
Glucosamine inhibits IL-1beta-induced NFkappaB activation in human osteoarthritic chondrocytes | Q44394411 | ||
Glucosamine and chondroitin sulfate: biological response modifiers of chondrocytes under simulated conditions of joint stress | Q44439622 | ||
The effects of ascorbic acid on cartilage metabolism in guinea pig articular cartilage explants | Q45711565 | ||
Fibronectin fragments mediate matrix metalloproteinase upregulation and cartilage damage through proline rich tyrosine kinase 2, c-src, NF-kappaB and protein kinase Cdelta. | Q46028651 | ||
Chondroitin sulfate increases hyaluronan production by human synoviocytes through differential regulation of hyaluronan synthases: Role of p38 and Akt. | Q46106596 | ||
Modification of the composition of articular cartilage collagen fibrils with increasing age. | Q46259243 | ||
Effect of glucosamine sulphate on joint space narrowing, pain and function in patients with hip osteoarthritis; subgroup analyses of a randomized controlled trial | Q46321177 | ||
The complex pathology of osteoarthritis: even mitochondria are involved | Q46453970 | ||
Glucosamine and chondroitin sulfate regulate gene expression and synthesis of nitric oxide and prostaglandin E(2) in articular cartilage explants | Q46480686 | ||
Effect of glucosamine sulfate on hip osteoarthritis: a randomized trial | Q46746770 | ||
Differing results of trials of glucosamine for pain in arthritis: comment on the article by VLAD et al. | Q46830088 | ||
Marginal efficacy of glucosamine: comment on the article by VLAD et al and the editorial by Reginster | Q46830098 | ||
Absorption, uptake and tissue affinity of high-molecular-weight hyaluronan after oral administration in rats and dogs | Q47209677 | ||
Chronic stress tolerance levels for human articular cartilage: two nonuniform contact models applied to long-term follow-up of CDH. | Q48541282 | ||
Effects of oral chondroitin sulfate on the progression of knee osteoarthritis: a pilot study | Q48592216 | ||
Glucosamine prevents in vitro collagen degradation in chondrocytes by inhibiting advanced lipoxidation reactions and protein oxidation | Q22000860 | ||
Glucosamine therapy for treating osteoarthritis | Q24244026 | ||
The effect of glucosamine and/or chondroitin sulfate on the progression of knee osteoarthritis: a report from the glucosamine/chondroitin arthritis intervention trial | Q24630475 | ||
Evaluation of symptomatic slow-acting drugs in osteoarthritis using the GRADE system | Q24647595 | ||
EULAR Recommendations 2003: an evidence based approach to the management of knee osteoarthritis: Report of a Task Force of the Standing Committee for International Clinical Studies Including Therapeutic Trials (ESCISIT) | Q24674132 | ||
Obesity and osteoarthritis: more complex than predicted! | Q24675065 | ||
Potential involvement of oxidative stress in cartilage senescence and development of osteoarthritis: oxidative stress induces chondrocyte telomere instability and downregulation of chondrocyte function | Q24804197 | ||
Membrane-associated prostaglandin E synthase-1 is upregulated by proinflammatory cytokines in chondrocytes from patients with osteoarthritis | Q24805523 | ||
Signalling pathway involved in nitric oxide synthase type II activation in chondrocytes: synergistic effect of leptin with interleukin-1 | Q24816719 | ||
Leptin enhances synthesis of proinflammatory mediators in human osteoarthritic cartilage--mediator role of NO in leptin-induced PGE2, IL-6, and IL-8 production | Q28115730 | ||
Matrix metalloproteinases | Q28140451 | ||
Free radicals, antioxidants, and nutrition | Q28205310 | ||
Collagen Synthesis in tenocytes, ligament cells and chondrocytes exposed to a combination of Glucosamine HCl and chondroitin sulfate | Q28212371 | ||
Do glucosamine and chondroitin treat the symptoms of osteoarthritis? | Q28354361 | ||
Glucosamine and chondroitin for treatment of osteoarthritis: a systematic quality assessment and meta-analysis | Q28374250 | ||
Genome-wide association scan identifies a prostaglandin-endoperoxide synthase 2 variant involved in risk of knee osteoarthritis | Q28943498 | ||
A randomized controlled trial on the efficacy and safety of a food ingredient, collagen hydrolysate, for improving joint comfort | Q29394573 | ||
Pathologic indicators of degradation and inflammation in human osteoarthritic cartilage are abrogated by exposure to n-3 fatty acids. | Q30836366 | ||
Prevalence and correlates of osteoarthritis in Germany. Representative data from the First National Health Survey | Q30990480 | ||
Long-term effects of glucosamine sulphate on osteoarthritis progression: a randomised, placebo-controlled clinical trial | Q32050561 | ||
Interleukin-1beta down-regulates the expression of glucuronosyltransferase I, a key enzyme priming glycosaminoglycan biosynthesis: influence of glucosamine on interleukin-1beta-mediated effects in rat chondrocytes | Q32067938 | ||
Intermittent treatment of knee osteoarthritis with oral chondroitin sulfate: a one-year, randomized, double-blind, multicenter study versus placebo | Q33199633 | ||
Osteoarthritis: a metabolic disease induced by local abnormal leptin activity? | Q33212755 | ||
Glucosamine long-term treatment and the progression of knee osteoarthritis: systematic review of randomized controlled trials | Q33214439 | ||
Clinical review of chondroitin sulfate in osteoarthritis | Q33357124 | ||
Cartilage integration: evaluation of the reasons for failure of integration during cartilage repair. A review. | Q33366624 | ||
Glucosamine increases hyaluronic acid production in human osteoarthritic synovium explants | Q33368886 | ||
The incidence of co-morbidities related to obesity and overweight: a systematic review and meta-analysis | Q33422129 | ||
Evaluation of the effect of antiarthritic drugs on the secretion of proteoglycans by lapine chondrocytes using a novel assay procedure | Q33561663 | ||
Effects of fish oil supplementation in rheumatoid arthritis | Q33562342 | ||
Genetics of osteoarthritis | Q33579265 | ||
Short-term gene expression changes in cartilage explants stimulated with interleukin beta plus glucosamine and chondroitin sulfate. | Q50478261 | ||
Metabolic and ultrastructural changes in articular cartilage of rats fed dietary supplements of omega-3 fatty acids. | Q50879603 | ||
Do antioxidant micronutrients protect against the development and progression of knee osteoarthritis? | Q51033276 | ||
Glucosamine modulates chondrocyte proliferation, matrix synthesis, and gene expression. | Q51161871 | ||
24-Week study on the use of collagen hydrolysate as a dietary supplement in athletes with activity-related joint pain. | Q51706290 | ||
A metaanalysis of chondroitin sulfate in the treatment of osteoarthritis. | Q55033577 | ||
The efficacy of glucosamine sulfate in osteoarthritis: financial and nonfinancial conflict of interest. | Q55044134 | ||
Osteoarthritis as a systemic disorder including stromal cell differentiation and lipid metabolism | Q56169415 | ||
Sex and ethnic differences in the association ofASPN,CALM1,COL2A1,COMP, andFRZB with genetic susceptibility to osteoarthritis of the knee | Q57445849 | ||
Cod liver oil (n-3 fatty acids) as an non-steroidal anti-inflammatory drug sparing agent in rheumatoid arthritis | Q61830864 | ||
Metabolic fate of exogenous chondroitin sulfate in the experimental animal | Q67294092 | ||
Fibronectin fragments cause chondrolysis of bovine articular cartilage slices in culture | Q67754603 | ||
Failure of selenium-ace to improve osteoarthritis | Q68519878 | ||
Fish-oil fatty acid supplementation in active rheumatoid arthritis. A double-blinded, controlled, crossover study | Q70168695 | ||
The relationship of obesity, fat distribution and osteoarthritis in women in the general population: the Chingford Study | Q70661807 | ||
Omega-3 fatty acids enhance ligament fibroblast collagen formation in association with changes in interleukin-6 production | Q73348681 | ||
Inflammation is a feature of the disease process in early knee joint osteoarthritis | Q73574859 | ||
The induction of cell death in human osteoarthritis chondrocytes by nitric oxide is related to the production of prostaglandin E2 via the induction of cyclooxygenase-2 | Q74279990 | ||
Nitric oxide mediates interleukin-1-induced gene expression of matrix metalloproteinases and basic fibroblast growth factor in cultured rabbit articular chondrocytes | Q74430431 | ||
Quantitative structural organization of normal adult human articular cartilage | Q74486244 | ||
Sites of collagenase cleavage and denaturation of type II collagen in aging and osteoarthritic articular cartilage and their relationship to the distribution of matrix metalloproteinase 1 and matrix metalloproteinase 13 | Q74714921 | ||
ERK-1/2 and p38 kinase oppositely regulate nitric oxide-induced apoptosis of chondrocytes in association with p53, caspase-3, and differentiation status | Q77105435 | ||
Inhibition of articular cartilage degradation by glucosamine-HCl and chondroitin sulphate | Q78444082 | ||
Increased oxidative stress and its relation with collagen metabolism in knee osteoarthritis | Q79345643 | ||
Status of lipid peroxidation, glutathione, ascorbic acid, vitamin E and antioxidant enzymes in patients with osteoarthritis | Q79467035 | ||
Glucosamine promotes chondrogenic phenotype in both chondrocytes and mesenchymal stem cells and inhibits MMP-13 expression and matrix degradation | Q79872147 | ||
Increased expression of the collagen receptor discoidin domain receptor 2 in articular cartilage as a key event in the pathogenesis of osteoarthritis | Q80707124 | ||
Chondrocyte senescence, joint loading and osteoarthritis | Q80851787 | ||
Osteoarthritis | Q81042522 | ||
Glucosamine therapy for osteoarthritis: an update | Q81042715 | ||
Chondroitins 4 and 6 sulfate in osteoarthritis of the knee: a randomized, controlled trial | Q81484755 | ||
Knee structural alteration and BMI: a cross-sectional study | Q81596030 | ||
Glycosaminoglycans modulate inflammation and apoptosis in LPS-treated chondrocytes | Q82607594 | ||
The rate of decline of joint space width in patients with osteoarthritis of the knee: a systematic review and meta-analysis of randomized placebo-controlled trials of chondroitin sulfate | Q95305820 | ||
The human pharmacokinetics of oral ingestion of glucosamine and chondroitin sulfate taken separately or in combination | Q33679221 | ||
NF-kappa B mediates the stimulation of cytokine and chemokine expression by human articular chondrocytes in response to fibronectin fragments | Q33992822 | ||
Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis | Q33993736 | ||
Dietary supplements for osteoarthritis. | Q34009777 | ||
Structural and symptomatic efficacy of glucosamine and chondroitin in knee osteoarthritis: a comprehensive meta-analysis | Q34214244 | ||
Osteoarthritis, an inflammatory disease: potential implication for the selection of new therapeutic targets | Q34283578 | ||
Risk factors for osteoarthritis: genetics | Q34286731 | ||
Synovial fluid levels and serum pharmacokinetics in a large animal model following treatment with oral glucosamine at clinically relevant doses | Q34383021 | ||
Efficacy of a combination of FCHG49 glucosamine hydrochloride, TRH122 low molecular weight sodium chondroitin sulfate and manganese ascorbate in the management of knee osteoarthritis | Q34510491 | ||
N-acetylglucosamine prevents IL-1 beta-mediated activation of human chondrocytes | Q34514554 | ||
Glucosamine modulates IL-1-induced activation of rat chondrocytes at a receptor level, and by inhibiting the NF-kappa B pathway | Q34520479 | ||
Glucosamine sulfate use and delay of progression of knee osteoarthritis: a 3-year, randomized, placebo-controlled, double-blind study | Q34528067 | ||
Glucosamine sulfate modulates the levels of aggrecan and matrix metalloproteinase-3 synthesized by cultured human osteoarthritis articular chondrocytes | Q34534426 | ||
The role of reactive oxygen species in homeostasis and degradation of cartilage | Q34537354 | ||
Glucosamine sulfate reduces osteoarthritis progression in postmenopausal women with knee osteoarthritis: evidence from two 3-year studies | Q34546341 | ||
Risk assessment for glucosamine and chondroitin sulfate | Q34570456 | ||
Glucosamine sulfate in the treatment of knee osteoarthritis symptoms: a randomized, double-blind, placebo-controlled study using acetaminophen as a side comparator | Q34574562 | ||
Current role of glucosamine in the treatment of osteoarthritis. | Q34578263 | ||
Total joint replacement after glucosamine sulphate treatment in knee osteoarthritis: results of a mean 8-year observation of patients from two previous 3-year, randomised, placebo-controlled trials. | Q34581685 | ||
Influence of glucosamine sulphate on oxidative stress in human osteoarthritic chondrocytes: effects on HO-1, p22(Phox) and iNOS expression. | Q34586059 | ||
Glucosamine for pain in osteoarthritis: why do trial results differ? | Q34643259 | ||
Glucosamine and chondroitin sulfate as therapeutic agents for knee and hip osteoarthritis | Q34656760 | ||
Chondrocyte-mediated catabolism of aggrecan: aggrecanase-dependent cleavage induced by interleukin-1 or retinoic acid can be inhibited by glucosamine | Q34752761 | ||
Glucosamine | Q34816926 | ||
Review article: Glucosamine | Q34978110 | ||
Nutritional management of rheumatoid arthritis: a review of the evidence | Q35093729 | ||
Body mass index associated with onset and progression of osteoarthritis of the knee but not of the hip: the Rotterdam Study | Q35638607 | ||
The effect of nutritional supplements on osteoarthritis | Q35896687 | ||
Epigenetic regulation of leptin affects MMP-13 expression in osteoarthritic chondrocytes: possible molecular target for osteoarthritis therapeutic intervention | Q36171836 | ||
Aggrecan, aging and assembly in articular cartilage. | Q36249555 | ||
Matrix metalloproteinases: role in arthritis | Q36251020 | ||
The effects of exercise on human articular cartilage | Q36459463 | ||
Effect of a natural extract of chicken combs with a high content of hyaluronic acid (Hyal-Joint) on pain relief and quality of life in subjects with knee osteoarthritis: a pilot randomized double-blind placebo-controlled trial | Q36464778 | ||
Genetic influences on osteoarthritis in women: a twin study | Q36598099 | ||
Cellular, molecular, and matrix changes in cartilage during aging and osteoarthritis | Q36691025 | ||
Low-selenium diet, bone, and articular cartilage in rats. | Q36698619 | ||
Effect of chondroitin sulphate in a rabbit model of atherosclerosis aggravated by chronic arthritis | Q36736328 | ||
Osteoarthritis: aging of matrix and cells--going for a remedy | Q36737794 | ||
TGF-beta and osteoarthritis | Q36773157 | ||
Osteoarthritis in 2007. | Q36964888 | ||
Obesity and osteoarthritis: disease genesis and nonpharmacologic weight management | Q37001372 | ||
Adipokines as emerging mediators of immune response and inflammation. | Q37014112 | ||
ADAMTS-5: the story so far. | Q37076199 | ||
Cartilage in normal and osteoarthritis conditions | Q37154103 | ||
Potential effects of chondroitin sulfate on joint swelling: a GAIT report | Q37167150 | ||
Developments in the clinical understanding of osteoarthritis | Q37207005 | ||
Articular cartilage: structure, injuries and review of management | Q37234022 | ||
Mitochondrial dysregulation of osteoarthritic human articular chondrocytes analyzed by proteomics: a decrease in mitochondrial superoxide dismutase points to a redox imbalance | Q37267822 | ||
Osteoarthritis: a tale of three tissues. | Q37304243 | ||
Immunomodulatory and anti-inflammatory effects of chondroitin sulphate | Q37310621 | ||
Obesity and the musculoskeletal system | Q37354006 | ||
Glucosamine and chondroitin for osteoarthritis | Q37354339 | ||
Adipokines in the skeleton: influence on cartilage function and joint degenerative diseases. | Q37400435 | ||
Does knee malalignment increase the risk of development and progression of knee osteoarthritis? A systematic review | Q37427642 | ||
A metabolic aspect of osteoarthritis: lipid as a possible contributor to the pathogenesis of cartilage degradation. | Q37497607 | ||
The effects of oral glucosamine on joint health: is a change in research approach needed? | Q37592565 | ||
Obesity and inflammation--targets for OA therapy. | Q37701900 | ||
The effects of contact pressure elevations and aseptic necrosis on the long-term outcome of congenital hip dislocation. | Q38095759 | ||
Human articular chondrocytes express functional leptin receptors | Q38297153 | ||
Differential expression of leptin and leptin's receptor isoform (Ob-Rb) mRNA between advanced and minimally affected osteoarthritic cartilage; effect on cartilage metabolism | Q38303866 | ||
Evidence for a key role of leptin in osteoarthritis | Q38348145 | ||
Cartilage contact pressure elevations in dysplastic hips: a chronic overload model | Q39103446 | ||
Sulfated glycosaminoglycans and glucosamine may synergize in promoting synovial hyaluronic acid synthesis | Q39429209 | ||
P275 | copyright license | Creative Commons Attribution 3.0 Unported | Q14947546 |
P6216 | copyright status | copyrighted | Q50423863 |
P921 | main subject | fatty acid | Q61476 |
glucosamine | Q32907954 | ||
P304 | page(s) | 969012 | |
P577 | publication date | 2011-08-02 | |
P1433 | published in | International journal of rheumatology | Q26853833 |
P1476 | title | Effects of Glucosamine and Chondroitin Sulfate on Cartilage Metabolism in OA: Outlook on Other Nutrient Partners Especially Omega-3 Fatty Acids | |
P478 | volume | 2011 |