| scholarly article | Q13442814 |
| P50 | author | Richard F Loeser | Q88623051 |
| P2093 | author name string | Hong Chen | |
| Sanjay Kumar | |||
| Hee-Jeong Im | |||
| Charles Hanning | |||
| Judit I Pulai | |||
| Priti S Hegde | |||
| P2860 | cites work | c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis | Q28343409 |
| The ?5?1 integrin provides matrix survival signals for normal and osteoarthritic human articular chondrocytes in vitro | Q29544119 | ||
| Signaling and circuitry of multiple MAPK pathways revealed by a matrix of global gene expression profiles | Q29620701 | ||
| Fibronectin fragment activation of proline-rich tyrosine kinase PYK2 mediates integrin signals regulating collagenase-3 expression by human chondrocytes through a protein kinase C-dependent pathway | Q30433820 | ||
| Mechanisms of chondrocyte apoptosis | Q33695655 | ||
| Inhibitory Effects of Insulin-like Growth Factor-1 and Osteogenic Protein-1 on Fibronectin Fragment- and Interleukin-1β-stimulated Matrix Metalloproteinase-13 Expression in Human Chondrocytes | Q33953821 | ||
| The role of the chondrocyte in osteoarthritis | Q34051076 | ||
| Identification and isolation of a 140 kd cell surface glycoprotein with properties expected of a fibronectin receptor | Q34686171 | ||
| Signal transduction through the fibronectin receptor induces collagenase and stromelysin gene expression | Q36221364 | ||
| The new collagenase, collagenase-3, is expressed and synthesized by human chondrocytes but not by synoviocytes. A role in osteoarthritis | Q37354475 | ||
| Hypoestoxide, a novel anti-inflammatory natural diterpene, inhibits the activity of IkappaB kinase | Q39319116 | ||
| Fibronectin-fragment-induced cartilage chondrolysis is associated with release of catabolic cytokines | Q42159855 | ||
| Chemokine production by human chondrocytes | Q42477798 | ||
| Human chondrocytes express functional chemokine receptors and release matrix-degrading enzymes in response to C-X-C and C-C chemokines | Q42492021 | ||
| Fibronectin fragments and blocking antibodies to alpha2beta1 and alpha5beta1 integrins stimulate mitogen-activated protein kinase signaling and increase collagenase 3 (matrix metalloproteinase 13) production by human articular chondrocytes | Q44159758 | ||
| Growth-related oncogene alpha induction of apoptosis in osteoarthritis chondrocytes | Q44250388 | ||
| Differential and regulated expression of C-X-C, C-C, and C-chemokines by human colon epithelial cells | Q44634002 | ||
| Cartilage and joint inflammation. Regulation of IL-8 expression by human articular chondrocytes. | Q46022546 | ||
| Production of the chemokine RANTES by articular chondrocytes and role in cartilage degradation | Q46179973 | ||
| IL-8/CXCL8 and growth-related oncogene alpha/CXCL1 induce chondrocyte hypertrophic differentiation | Q46534914 | ||
| Gene deletion of either interleukin-1beta, interleukin-1beta-converting enzyme, inducible nitric oxide synthase, or stromelysin 1 accelerates the development of knee osteoarthritis in mice after surgical transection of the medial collateral ligament | Q50491685 | ||
| Characterization of cells from pannus-like tissue over articular cartilage of advanced osteoarthritis. | Q54735894 | ||
| Down-modulation of chemokine receptor cartilage expression in inflammatory arthritis. | Q54797188 | ||
| Flow cytometric analysis of intracellular chemokines in chondrocytes in vivo: constitutive expression and enhancement in osteoarthritis and rheumatoid arthritis | Q57012210 | ||
| Heterogeneous requirement of IkappaB kinase 2 for inflammatory cytokine and matrix metalloproteinase production in rheumatoid arthritis: implications for therapy | Q60169453 | ||
| Fibronectin fragments alter matrix protein synthesis in cartilage tissue cultured in vitro. | Q64898546 | ||
| IL-6 production by human articular chondrocytes. Modulation of its synthesis by cytokines, growth factors, and hormones in vitro | Q67267390 | ||
| Fibronectin fragments cause chondrolysis of bovine articular cartilage slices in culture | Q67754603 | ||
| Fibronectin fragments in osteoarthritic synovial fluid | Q67928985 | ||
| Induction of synthesis and release of interleukin-8 from human articular chondrocytes and cartilage explants | Q67973891 | ||
| Characterization of synovial fluid fibronectin from patients with rheumatic inflammatory diseases and healthy subjects | Q70580990 | ||
| Signal transduction through chondrocyte integrin receptors induces matrix metalloproteinase synthesis and synergizes with interleukin-1 | Q71781212 | ||
| Cartilage chondrolysis by fibronectin fragments is associated with release of several proteinases: stromelysin plays a major role in chondrolysis | Q72519020 | ||
| Disease-modifying activity of SB 242235, a selective inhibitor of p38 mitogen-activated protein kinase, in rat adjuvant-induced arthritis | Q73374754 | ||
| Functional genomic analysis in arthritis-affected cartilage: yin-yang regulation of inflammatory mediators by alpha 5 beta 1 and alpha V beta 3 integrins | Q73458481 | ||
| Regulation of angiogenesis by the C-X-C chemokines interleukin-8 and epithelial neutrophil activating peptide 78 in the rheumatoid joint | Q73521731 | ||
| Sites of collagenase cleavage and denaturation of type II collagen in aging and osteoarthritic articular cartilage and their relationship to the distribution of matrix metalloproteinase 1 and matrix metalloproteinase 13 | Q74714921 | ||
| Stimulation of matrix metalloprotease 3 release from human chondrocytes by the interaction of stromal cell-derived factor 1 and CXC chemokine receptor 4 | Q77567376 | ||
| Cartilage damaging activities of fibronectin fragments derived from cartilage and synovial fluid | Q77756107 | ||
| Subtyping of osteoarthritic synoviopathy | Q78462899 | ||
| P433 | issue | 9 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | NF-κB | Q411114 |
| P304 | page(s) | 5781-5788 | |
| P577 | publication date | 2005-05-01 | |
| P1433 | published in | Journal of Immunology | Q3521441 |
| P1476 | title | NF-kappa B mediates the stimulation of cytokine and chemokine expression by human articular chondrocytes in response to fibronectin fragments | |
| P478 | volume | 174 |
| Q42964193 | A novel rose hip preparation with enhanced anti-inflammatory and chondroprotective effects |
| Q43284355 | ADAM-8 isolated from human osteoarthritic chondrocytes cleaves fibronectin at Ala(271). |
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| Q37599914 | Analysing the role of endogenous matrix molecules in the development of osteoarthritis. |
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| Q51808615 | Attenuation of experimental autoimmune myocarditis by blocking T cell activation through 4-1BB pathway. |
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| Q50925610 | Basic fibroblast growth factor activates the MAPK and NFkappaB pathways that converge on Elk-1 to control production of matrix metalloproteinase-13 by human adult articular chondrocytes. |
| Q37358102 | Basic fibroblast growth factor induces matrix metalloproteinase-13 via ERK MAP kinase-altered phosphorylation and sumoylation of Elk-1 in human adult articular chondrocytes. |
| Q33953872 | Basic fibroblast growth factor stimulates matrix metalloproteinase-13 via the molecular cross-talk between the mitogen-activated protein kinases and protein kinase Cdelta pathways in human adult articular chondrocytes |
| Q37253391 | Basic science of osteoarthritis |
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| Q34658865 | Borrelia burgdorferi HtrA may promote dissemination and irritation |
| Q45033867 | Borrelia burgdorferi BbHtrA degrades host ECM proteins and stimulates release of inflammatory cytokines in vitro |
| Q36612357 | Bovine lactoferricin induces TIMP-3 via the ERK1/2-Sp1 axis in human articular chondrocytes |
| Q34236851 | CCAAT/enhancer-binding protein β and NF-κB mediate high level expression of chemokine genes CCL3 and CCL4 by human chondrocytes in response to IL-1β. |
| Q40191634 | CD40 ligand binds to alpha5beta1 integrin and triggers cell signaling |
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| Q36849295 | Cysteine-Mediated Redox Regulation of Cell Signaling in Chondrocytes Stimulated With Fibronectin Fragments. |
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| Q35830240 | Effect of GCSB-5, a Herbal Formulation, on Monosodium Iodoacetate-Induced Osteoarthritis in Rats. |
| Q24649140 | Effect of interleukin-1beta on osteogenic protein 1-induced signaling in adult human articular chondrocytes |
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| Q51758259 | Emerging Players at the Intersection of Chondrocyte Loss of Maturational Arrest, Oxidative Stress, Senescence and Low-Grade Inflammation in Osteoarthritis. |
| Q35842797 | Endogenous production of reactive oxygen species is required for stimulation of human articular chondrocyte matrix metalloproteinase production by fibronectin fragments |
| Q39842834 | Expression of Toll-like receptor 4 in the prostate gland and its association with the severity of prostate cancer |
| Q37021518 | Exuberant expression of chemokine genes by adult human articular chondrocytes in response to IL-1beta. |
| Q35617712 | Fibroblast growth factor receptor 1 is principally responsible for fibroblast growth factor 2-induced catabolic activities in human articular chondrocytes |
| Q36934976 | Fibroblast growth factor-2 promotes catabolism via FGFR1-Ras-Raf-MEK1/2-ERK1/2 axis that coordinates with the PKCδ pathway in human articular chondrocytes |
| Q36276352 | Fibronectin fragment-induced expression of matrix metalloproteinases is mediated by MyD88-dependent TLR-2 signaling pathway in human chondrocytes |
| Q38113681 | Fibronectin in tissue regeneration: timely disassembly of the scaffold is necessary to complete the build |
| Q40308412 | Fibronectin induces cell proliferation and inhibits apoptosis in human bronchial epithelial cells: pro-oncogenic effects mediated by PI3-kinase and NF-kappa B. |
| Q34629775 | Fibronectin: functional character and role in alcoholic liver disease |
| Q37730952 | Functions of nuclear factor kappaB in bone |
| Q36391737 | Genome-wide analysis of pain-, nerve- and neurotrophin -related gene expression in the degenerating human annulus |
| Q42056374 | Heparin-binding epidermal growth factor-like growth factor (HB-EGF) is increased in osteoarthritis and regulates chondrocyte catabolic and anabolic activities |
| Q37706611 | Homeostatic mechanisms in articular cartilage and role of inflammation in osteoarthritis |
| Q36641543 | Human articular chondrocytes produce IL-7 and respond to IL-7 with increased production of matrix metalloproteinase-13. |
| Q37690081 | Hyaluronic acid fragments enhance the inflammatory and catabolic response in human intervertebral disc cells through modulation of toll-like receptor 2 signalling pathways |
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| Q38949744 | In vivo luminescence imaging of NF-κB activity and serum cytokine levels predict pain sensitivities in a rodent model of osteoarthritis |
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| Q41870533 | Inflammatory conditions partly impair the mechanically mediated activation of Smad2/3 signaling in articular cartilage |
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| Q34475498 | OARSI Clinical Trials Recommendations: Soluble biomarker assessments in clinical trials in osteoarthritis. |
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