scholarly article | Q13442814 |
review article | Q7318358 |
P2093 | author name string | Dae Gwin Jeong | |
Moo-Seung Lee | |||
Vernon L Tesh | |||
Sunwoo Koo | |||
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Signal integration in the endoplasmic reticulum unfolded protein response | Q27860577 | ||
Mediators of endoplasmic reticulum stress-induced apoptosis | Q29615496 | ||
The unfolded protein response: controlling cell fate decisions under ER stress and beyond | Q29615499 | ||
Food-related illness and death in the United States | Q29615940 | ||
Self-eating and self-killing: crosstalk between autophagy and apoptosis | Q29617748 | ||
Quality control in the endoplasmic reticulum | Q29619929 | ||
Rapid Apoptosis Induced by Shiga Toxin in HeLa Cells | Q30310781 | ||
Monocyte chemoattractant protein 1, macrophage inflammatory protein 1 alpha, and RANTES recruit macrophages to the kidney in a mouse model of hemolytic-uremic syndrome | Q30442593 | ||
Ultrasound contrast microbubbles in imaging and therapy: physical principles and engineering | Q30482585 | ||
Probing the surface of eukaryotic cells using combinatorial toxin libraries | Q30699689 | ||
Activation of the caspase cascade during Stx1-induced apoptosis in Burkitt's lymphoma cells | Q31948409 | ||
The glycosphingolipid globotriaosylceramide in the metastatic transformation of colon cancer | Q33229926 | ||
Retrograde delivery of photosensitizer (TPPp-O-beta-GluOH)3 selectively potentiates its photodynamic activity | Q33315429 | ||
Binding and transfer of verocytotoxin by polymorphonuclear leukocytes in hemolytic uremic syndrome | Q33332577 | ||
Detection of apoptosis in kidney biopsies of patients with D+ hemolytic uremic syndrome. | Q33336219 | ||
Tumor necrosis factor and interleukin-1 induce expression of the verocytotoxin receptor globotriaosylceramide on human endothelial cells: implications for the pathogenesis of the hemolytic uremic syndrome | Q33351371 | ||
Early alterations of B cells in patients with septic shock: another piece in the complex puzzle of the immune response in sepsis | Q33356168 | ||
Escherichia coli Shiga toxin 1 and TNF-alpha induce cytokine release by human cerebral microvascular endothelial cells | Q33359854 | ||
Shiga-toxin-producing Escherichia coli and haemolytic uraemic syndrome | Q33365488 | ||
Epidemiology of Escherichia coli O157:H7 outbreaks, United States, 1982-2002. | Q33365831 | ||
Economic cost of illness due to Escherichia coli O157 infections in the United States | Q33369600 | ||
Interactions between Shiga toxins and human polymorphonuclear leukocytes | Q33380350 | ||
Shiga toxin-associated hemolytic uremic syndrome and thrombotic thrombocytopenic purpura: distinct mechanisms of pathogenesis | Q33383009 | ||
The association of Shiga-like toxin with detergent-resistant membranes is modulated by glucosylceramide and is an essential requirement in the endoplasmic reticulum for a cytotoxic effect | Q34407346 | ||
Shigellosis or bacillary dysentery | Q34578237 | ||
Neuronal apoptosis and inflammatory responses in the central nervous system of a rabbit treated with Shiga toxin-2 | Q34589587 | ||
Shiga toxin 1 triggers a ribotoxic stress response leading to p38 and JNK activation and induction of apoptosis in intestinal epithelial cells | Q34715023 | ||
Shiga toxin induces tubular membrane invaginations for its uptake into cells | Q34719609 | ||
Regulation of innate immunity through RNA structure and the protein kinase PKR. | Q34786169 | ||
Effects of Shiga toxin type 2 on a bioengineered three-dimensional model of human renal tissue | Q34889826 | ||
Human breast cancer and lymph node metastases express Gb3 and can be targeted by STxB-vectorized chemotherapeutic compounds. | Q34897367 | ||
The treatment of malignant meningioma with verotoxin | Q34929060 | ||
Shiga toxin receptor glycolipid binding. Pathology and utility | Q34957504 | ||
Shiga toxin interactions with the intestinal epithelium | Q34957615 | ||
Shiga toxin 2-induced endoplasmic reticulum stress is minimized by activated protein C but does not correlate with lethal kidney injury. | Q35003696 | ||
A novel mechanism of bacterial toxin transfer within host blood cell-derived microvesicles | Q35125841 | ||
Differential response of the human renal proximal tubular epithelial cell line HK-2 to Shiga toxin types 1 and 2. | Q35191964 | ||
Glycolipid binding preferences of Shiga toxin variants | Q35199053 | ||
Shiga toxins induce autophagy leading to differential signalling pathways in toxin-sensitive and toxin-resistant human cells | Q35214193 | ||
Differentiation-associated toxin receptor modulation, cytokine production, and sensitivity to Shiga-like toxins in human monocytes and monocytic cell lines. | Q35480200 | ||
Ribosome-inactivating proteins: entry into mammalian cells and intracellular routing | Q35794001 | ||
Shiga toxins induce autophagic cell death in intestinal epithelial cells via the endoplasmic reticulum stress pathway | Q35852939 | ||
Survival and apoptosis signals in ER stress: the role of protein kinases. | Q35885350 | ||
Protein toxins: intracellular trafficking for targeted therapy. | Q36132002 | ||
Multicenter evaluation of a sequence-based protocol for subtyping Shiga toxins and standardizing Stx nomenclature | Q36172302 | ||
Shiga Toxins Activate the NLRP3 Inflammasome Pathway To Promote Both Production of the Proinflammatory Cytokine Interleukin-1β and Apoptotic Cell Death | Q36410999 | ||
Binding of adenine to Stx2, the protein toxin from Escherichia coli O157:H7. | Q36459565 | ||
Estimates of illnesses, hospitalizations and deaths caused by major bacterial enteric pathogens in young children in the United States | Q41404343 | ||
Apoptosis induced in Burkitt's lymphoma cells via Gb3/CD77, a glycolipid antigen. | Q41517521 | ||
Accumulating evidence suggests that several AB-toxins subvert the endoplasmic reticulum-associated protein degradation pathway to enter target cells | Q41614148 | ||
Toxin-induced cell lysis: protection by 3-methyladenine and cycloheximide | Q41985394 | ||
Shiga toxin is transported from the endoplasmic reticulum following interaction with the luminal chaperone HEDJ/ERdj3. | Q42065084 | ||
Kinetic analysis of binding between Shiga toxin and receptor glycolipid Gb3Cer by surface plasmon resonance | Q43738152 | ||
Molecular basis for up-regulation by inflammatory cytokines of Shiga toxin 1 cytotoxicity and globotriaosylceramide expression | Q44137094 | ||
Induction of apoptosis of human brain microvascular endothelial cells by shiga toxin 1. | Q44267023 | ||
Shiga toxin induces decreased expression of the anti-apoptotic protein Mcl-1 concomitant with the onset of endothelial apoptosis | Q44538969 | ||
Structure of shiga toxin type 2 (Stx2) from Escherichia coli O157:H7. | Q44838252 | ||
Verotoxin induces apoptosis and the complete, rapid, long-term elimination of human astrocytoma xenografts in nude mice | Q44901937 | ||
Inhibitory effect of tyrphostin 47 on Shiga toxin-induced cell death. | Q44934045 | ||
Human colorectal tumors and metastases express Gb3 and can be targeted by an intestinal pathogen-based delivery tool | Q46440038 | ||
Shiga toxin B-subunit binds to the chaperone BiP and the nucleolar protein B23. | Q46457210 | ||
Inoculum size in shigellosis and implications for expected mode of transmission | Q47172816 | ||
Shiga-like toxin-1 receptor on human breast cancer, lymphoma, and myeloma and absence from CD34(+) hematopoietic stem cells: implications for ex vivo tumor purging and autologous stem cell transplantation. | Q47622602 | ||
Interaction of Shiga toxins with human brain microvascular endothelial cells: cytokines as sensitizing agents | Q48117465 | ||
Furin-induced cleavage and activation of Shiga toxin | Q49165095 | ||
Insertion and orientation of a synthetic peptide representing the C-terminus of the A1 domain of Shiga toxin into phospholipid membranes. | Q50537524 | ||
A new delivery system for auristatin in STxB-drug conjugate therapy. | Q50992264 | ||
Tumor delivery of ultrasound contrast agents using Shiga toxin B subunit. | Q51585578 | ||
Shiga toxin-mediated retrograde delivery of a topoisomerase I inhibitor prodrug. | Q51795901 | ||
In vivo tumor targeting using a novel intestinal pathogen-based delivery approach. | Q53528575 | ||
Isolation and characterization of Shigella shigae cytotoxin. | Q54559095 | ||
A new route of transmission for Escherichia coli: infection from dry fermented salami. | Q54584730 | ||
Verotoxin receptor glycolipid in human renal tissue. | Q54736253 | ||
Membrane cytosolic translocation of verotoxin A1 subunit in target cells. | Q54737751 | ||
Reflexion contrast, a new microscopic technic | Q55032717 | ||
Hemolytic uremic syndrome | Q57701679 | ||
Cytokine secretion in acute shigellosis is correlated to disease activity and directed more to stool than to plasma | Q58823347 | ||
Retrograde transport of endocytosed Shiga toxin to the endoplasmic reticulum | Q59097697 | ||
Microinjected oligonucleotides complementary to the alpha-sarcin loop of 28 S RNA abolish protein synthesis in Xenopus oocytes | Q68708746 | ||
Verocytotoxin-1 induces apoptosis in vero cells | Q72056217 | ||
Role of processing and intracellular transport for optimal toxicity of Shiga toxin and toxin mutants | Q72210047 | ||
Escherichia coli O157:H7 strains associated with haemorrhagic colitis in the United States produce a Shigella dysenteriae 1 (SHIGA) like cytotoxin | Q72548803 | ||
Role of the disulfide bond in Shiga toxin A-chain for toxin entry into cells | Q73248328 | ||
Apoptosis of renal tubular cells in Shiga-toxin-mediated hemolytic uremic syndrome | Q73599335 | ||
Increased serum IL-10 and endothelin levels in hemolytic uremic syndrome caused by Escherichia coli O157 | Q73644789 | ||
Escherichia coli Shiga toxins induce apoptosis in epithelial cells that is regulated by the Bcl-2 family | Q73761493 | ||
Orientation in lipid bilayers of a synthetic peptide representing the C-terminus of the A1 domain of shiga toxin. A polarized ATR-FTIR study | Q73940499 | ||
Shiga toxins | Q74609189 | ||
Shiga toxins--not just cytotoxins anymore | Q77308431 | ||
Hemolytic uremic syndrome and death in persons with Escherichia coli O157:H7 infection, foodborne diseases active surveillance network sites, 2000-2006. | Q33386636 | ||
Distinct physiologic and inflammatory responses elicited in baboons after challenge with Shiga toxin type 1 or 2 from enterohemorrhagic Escherichia coli | Q33388849 | ||
Endothelial damage induced by Shiga toxins delivered by neutrophils during transmigration | Q33389052 | ||
Complement activation on platelet-leukocyte complexes and microparticles in enterohemorrhagic Escherichia coli-induced hemolytic uremic syndrome | Q33394691 | ||
Characterisation of the Escherichia coli strain associated with an outbreak of haemolytic uraemic syndrome in Germany, 2011: a microbiological study | Q33395933 | ||
German outbreak of Escherichia coli O104:H4 associated with sprouts | Q33397821 | ||
Microparticle generation and leucocyte death in Shiga toxin-mediated HUS. | Q33399130 | ||
Shiga toxin 1 induces on lipopolysaccharide-treated astrocytes the release of tumor necrosis factor-alpha that alter brain-like endothelium integrity | Q33400603 | ||
Shiga toxins and the pathophysiology of hemolytic uremic syndrome in humans and animals | Q33404640 | ||
Distinct renal pathology and a chemotactic phenotype after enterohemorrhagic Escherichia coli shiga toxins in non-human primate models of hemolytic uremic syndrome | Q33405827 | ||
Identification of TLR4 as the receptor that recognizes Shiga toxins in human neutrophils | Q33410575 | ||
Expression of verotoxin-1 receptor Gb3 in breast cancer tissue and verotoxin-1 signal transduction to apoptosis | Q33412880 | ||
Upregulation of Shiga toxin receptor CD77/Gb3 and interleukin-1β expression in the brain of EHEC patients with hemolytic uremic syndrome and neurologic symptoms | Q33416244 | ||
Overview and Historical Perspectives | Q33419782 | ||
Effects of verocytotoxin-1 on nonadherent human monocytes: binding characteristics, protein synthesis, and induction of cytokine release. | Q33496269 | ||
Effects of TNF alpha on verocytotoxin cytotoxicity in purified human glomerular microvascular endothelial cells. | Q33498793 | ||
Apoptosis of renal cortical cells in the hemolytic-uremic syndrome: in vivo and in vitro studies | Q33501527 | ||
Chemokine expression in the monocytic cell line THP-1 in response to purified shiga toxin 1 and/or lipopolysaccharides | Q33557728 | ||
Shiga toxin-induced tumor necrosis factor alpha expression: requirement for toxin enzymatic activity and monocyte protein kinase C and protein tyrosine kinases | Q33599604 | ||
Global burden of Shigella infections: implications for vaccine development and implementation of control strategies | Q33749510 | ||
Induction of verotoxin sensitivity in receptor-deficient cell lines using the receptor glycolipid globotriosylceramide | Q33837961 | ||
Dr. Kiyoshi Shiga: discoverer of the dysentery bacillus | Q33877398 | ||
Characterization of Shigella dysenteriae 1 (Shiga) toxin purified by anti-Shiga toxin affinity chromatography | Q33909058 | ||
Targeting of Shiga toxin B-subunit to retrograde transport route in association with detergent-resistant membranes | Q33944092 | ||
Shiga toxin 2 and flagellin from shiga-toxigenic Escherichia coli superinduce interleukin-8 through synergistic effects on host stress-activated protein kinase activation | Q33963113 | ||
Hematopoietic cell kinase associates with the 40S ribosomal subunit and mediates the ribotoxic stress response to deoxynivalenol in mononuclear phagocytes | Q33988602 | ||
Signaling through C/EBP homologous protein and death receptor 5 and calpain activation differentially regulate THP-1 cell maturation-dependent apoptosis induced by Shiga toxin type 1 | Q34045050 | ||
Site of action of a Vero toxin (VT2) from Escherichia coli O157:H7 and of Shiga toxin on eukaryotic ribosomes. RNA N-glycosidase activity of the toxins. | Q34049372 | ||
Structure, biological functions and applications of the AB5 toxins | Q34102115 | ||
Role of tumor necrosis factor alpha in disease using a mouse model of Shiga toxin-mediated renal damage. | Q34119320 | ||
Shiga toxin binding to glycolipids and glycans | Q34163196 | ||
Vero response to a cytotoxin of Escherichia coli | Q34177128 | ||
Caspases: a molecular switch node in the crosstalk between autophagy and apoptosis | Q34284072 | ||
Shiga toxins | Q34298388 | ||
Macropinocytosis in Shiga toxin 1 uptake by human intestinal epithelial cells and transcellular transcytosis | Q37086199 | ||
Protein kinase PKR-dependent activation of mitogen-activated protein kinases occurs through mitochondrial adapter IPS-1 and is antagonized by vaccinia virus E3L. | Q37191825 | ||
Shiga toxin 1-induced proinflammatory cytokine production is regulated by the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin signaling pathway | Q37333366 | ||
Enterohemorrhagic Escherichia coli suppresses inflammatory response to cytokines and its own toxin | Q37337686 | ||
Bcl-2 regulates the onset of shiga toxin 1-induced apoptosis in THP-1 cells | Q37451195 | ||
Shiga toxins--from cell biology to biomedical applications | Q37659792 | ||
Endoplasmic Reticulum Stress and BCL-2 Family Members | Q37797389 | ||
Shiga toxin and its use in targeted cancer therapy and imaging | Q37831422 | ||
Multiple organ failure in sepsis: prognosis and role of systemic inflammatory response | Q37846478 | ||
How ricin and Shiga toxin reach the cytosol of target cells: retrotranslocation from the endoplasmic reticulum | Q37901423 | ||
Characteristics of the Shiga-toxin-producing enteroaggregative Escherichia coli O104:H4 German outbreak strain and of STEC strains isolated in Spain. | Q37958640 | ||
The induction of apoptosis by Shiga toxins and ricin | Q37963278 | ||
Autophagy, apoptosis, mitoptosis and necrosis: interdependence between those pathways and effects on cancer | Q38066407 | ||
The role of cell signalling in the crosstalk between autophagy and apoptosis | Q38168965 | ||
Shiga toxins expressed by human pathogenic bacteria induce immune responses in host cells | Q38175364 | ||
Lipid requirements for entry of protein toxins into cells | Q38181787 | ||
Unfolded protein response in hepatitis C virus infection | Q38218108 | ||
Microbe- and danger-induced inflammation | Q38231107 | ||
Bacteria, the endoplasmic reticulum and the unfolded protein response: friends or foes? | Q38298375 | ||
Affinities of Shiga toxins 1 and 2 for univalent and oligovalent Pk-trisaccharide analogs measured by electrospray ionization mass spectrometry | Q38299354 | ||
Interaction of the Shiga-like toxin type 1 B-subunit with its carbohydrate receptor | Q38301508 | ||
A role for the protease-sensitive loop region of Shiga-like toxin 1 in the retrotranslocation of its A1 domain from the endoplasmic reticulum lumen | Q38328315 | ||
Solution structure of the complex between the B-subunit homopentamer of verotoxin VT-1 from Escherichia coli and the trisaccharide moiety of globotriaosylceramide. | Q38334764 | ||
Regulation of cytokine and chemokine expression by the ribotoxic stress response elicited by Shiga toxin type 1 in human macrophage-like THP-1 cells | Q39376598 | ||
Tumor-specific targeting of pancreatic cancer with Shiga toxin B-subunit | Q39501025 | ||
Caspase-8-mediated cleavage of Bid and protein phosphatase 2A-mediated activation of Bax are necessary for Verotoxin-1-induced apoptosis in Burkitt's lymphoma cells | Q39778110 | ||
In vivo tumor targeting by the B-subunit of shiga toxin | Q39898598 | ||
ZAK: a MAP3Kinase that transduces Shiga toxin- and ricin-induced proinflammatory cytokine expression. | Q40003950 | ||
Effects of the VEGFR inhibitor ZD6474 in combination with radiotherapy and temozolomide in an orthotopic glioma model | Q40019510 | ||
Ribotoxic stress response: activation of the stress-activated protein kinase JNK1 by inhibitors of the peptidyl transferase reaction and by sequence-specific RNA damage to the alpha-sarcin/ricin loop in the 28S rRNA. | Q40022423 | ||
Shiga toxin 1 induces apoptosis through the endoplasmic reticulum stress response in human monocytic cells | Q40051377 | ||
Verotoxin-1 stimulation of macrophage-like THP-1 cells up-regulates tissue factor expression through activation of c-Yes tyrosine kinase: Possible signal transduction in tissue factor up-regulation | Q40239876 | ||
Role of Shiga toxin versus H7 flagellin in enterohaemorrhagic Escherichia coli signalling of human colon epithelium in vivo. | Q40293264 | ||
Shiga toxin 1-induced cytokine production is mediated by MAP kinase pathways and translation initiation factor eIF4E in the macrophage-like THP-1 cell line | Q40348838 | ||
Comparative evaluation of apoptosis induced by Shiga toxin 1 and/or lipopolysaccharides in human monocytic and macrophage-like cells. | Q40450494 | ||
Regulation of proinflammatory cytokine expression by Shiga toxin 1 and/or lipopolysaccharides in the human monocytic cell line THP-1 | Q40564019 | ||
Verotoxin induces rapid elimination of human renal tumor xenografts in SCID mice | Q40591684 | ||
Verotoxin sensitivity of ECV304 cells in vitro and in vivo in a xenograft tumour model: VT1 as a tumour neovascular marker | Q40596409 | ||
Two distinct Gb3/CD77 signaling pathways leading to apoptosis are triggered by anti-Gb3/CD77 mAb and verotoxin-1. | Q40639628 | ||
Role of double-stranded RNA-activated protein kinase R (PKR) in deoxynivalenol-induced ribotoxic stress response | Q40644043 | ||
Shiga toxin 1-induced activation of c-Jun NH(2)-terminal kinase and p38 in the human monocytic cell line THP-1: possible involvement in the production of TNF-alpha. | Q40758329 | ||
Novel role for JNK as a stress-activated Bcl2 kinase | Q40809860 | ||
The identification of three biologically relevant globotriaosyl ceramide receptor binding sites on the Verotoxin 1 B subunit | Q40949783 | ||
Translocation of verotoxin-1 across T84 monolayers: mechanism of bacterial toxin penetration of epithelium | Q41070932 | ||
Bcl-2 phosphorylation required for anti-apoptosis function | Q41111068 | ||
P275 | copyright license | Creative Commons Attribution | Q6905323 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 3 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | enzyme | Q8047 |
pathogenesis | Q372016 | ||
P304 | page(s) | 77 | |
P577 | publication date | 2016-03-01 | |
2016-03-17 | |||
P1433 | published in | Toxins | Q15724569 |
P1476 | title | Shiga Toxins as Multi-Functional Proteins: Induction of Host Cellular Stress Responses, Role in Pathogenesis and Therapeutic Applications | |
P478 | volume | 8 |
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