scholarly article | Q13442814 |
P50 | author | Yuan-Chi Teng | Q87057418 |
P2093 | author name string | Ting-Fen Tsai | |
Cheng-Heng Kao | |||
Zhao-Qing Shen | |||
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Nucling mediates apoptosis by inhibiting expression of galectin-3 through interference with nuclear factor kappaB signalling | Q24307907 | ||
Telomerase inhibitor PinX1 provides a link between TRF1 and telomerase to prevent telomere elongation | Q24310189 | ||
Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor | Q24569647 | ||
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SHP2 and SOCS3 contribute to Tyr-759-dependent attenuation of interleukin-6 signaling through gp130 | Q28211408 | ||
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Clinical significance of increased expression of Nijmegen breakage syndrome gene (NBS1) in human primary liver cancer | Q28265438 | ||
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Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver | Q28587974 | ||
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Absence of the SRC-2 coactivator results in a glycogenopathy resembling Von Gierke's disease | Q28592482 | ||
Nbn heterozygosity renders mice susceptible to tumor formation and ionizing radiation-induced tumorigenesis | Q28594255 | ||
Hepatitis B virus nucleocapsid particles do not cross the hepatocyte nuclear membrane in transgenic mice | Q28776764 | ||
Autophagy regulates lipid metabolism | Q29547421 | ||
The role of autophagy during the early neonatal starvation period | Q29547489 | ||
WNT signalling pathways as therapeutic targets in cancer | Q29615666 | ||
Gp78, an E3 ubiquitin ligase acts as a gatekeeper suppressing nonalcoholic steatohepatitis (NASH) and liver cancer | Q35581153 | ||
Noncoding RNA as therapeutic targets for hepatocellular carcinoma. | Q35592207 | ||
Spontaneous hepatocarcinogenesis in farnesoid X receptor-null mice | Q35765708 | ||
NF-κB in the liver--linking injury, fibrosis and hepatocellular carcinoma | Q35808323 | ||
PTPRO-mediated autophagy prevents hepatosteatosis and tumorigenesis | Q35832384 | ||
Mice with homozygous disruption of the mdr2 P-glycoprotein gene. A novel animal model for studies of nonsuppurative inflammatory cholangitis and hepatocarcinogenesis | Q35834086 | ||
High-level hepatitis B virus replication in transgenic mice | Q35847850 | ||
Interleukin-12 inhibits hepatitis B virus replication in transgenic mice | Q35881471 | ||
Targeting the interleukin-6/Jak/stat pathway in human malignancies | Q35925127 | ||
Mechanistic and prognostic significance of aberrant methylation in the molecular pathogenesis of human hepatocellular carcinoma | Q35945177 | ||
Hepatocarcinogenesis in FXR-/- mice mimics human HCC progression that operates through HNF1α regulation of FXR expression | Q35970148 | ||
A Sleeping Beauty mutagenesis screen reveals a tumor suppressor role for Ncoa2/Src-2 in liver cancer. | Q35991536 | ||
Sak/Plk4 and mitotic fidelity | Q36004665 | ||
MicroRNA-122 plays a critical role in liver homeostasis and hepatocarcinogenesis | Q36129123 | ||
Enhanced hepatocarcinogenesis in mouse models and human hepatocellular carcinoma by coordinate KLF6 depletion and increased messenger RNA splicing | Q36141301 | ||
Tumor suppressor genetics | Q36252762 | ||
Tumor development: haploinsufficiency and local network assembly | Q36285535 | ||
HBV induced carcinogenesis | Q36388400 | ||
Hepatitis B virus X protein targets Bcl-2 proteins to increase intracellular calcium, required for virus replication and cell death induction | Q36389447 | ||
Hepatitis B virus X protein targets the Bcl-2 protein CED-9 to induce intracellular Ca2+ increase and cell death in Caenorhabditis elegans | Q36389497 | ||
Immune pathogenesis of hepatocellular carcinoma. | Q36401448 | ||
SOCS1 is a suppressor of liver fibrosis and hepatitis-induced carcinogenesis | Q36402678 | ||
Downregulation of KLF6 is an early event in hepatocarcinogenesis, and stimulates proliferation while reducing differentiation. | Q36497062 | ||
Hepatitis B virus-related hepatocellular carcinoma: paradigms for viral-related human carcinogenesis | Q36519025 | ||
Hepatitis B virus pre-S mutants, endoplasmic reticulum stress and hepatocarcinogenesis | Q36545096 | ||
TRIM24 suppresses development of spontaneous hepatic lipid accumulation and hepatocellular carcinoma in mice | Q36633583 | ||
Loss of the glycine N-methyltransferase gene leads to steatosis and hepatocellular carcinoma in mice | Q36688699 | ||
Defects in inositol 1,4,5-trisphosphate receptor expression, Ca(2+) signaling, and insulin secretion in the anx7(+/-) knockout mouse | Q36701660 | ||
Hepatitis B virus transactivator X protein is not tumorigenic in transgenic mice | Q36796019 | ||
Tissue preferential expression of the hepatitis B virus (HBV) surface antigen gene in two lines of HBV transgenic mice | Q36827049 | ||
Developmental regulation of hepatitis B surface antigen expression in two lines of hepatitis B virus transgenic mice | Q36830784 | ||
Expression of hepatitis B virus large envelope polypeptide inhibits hepatitis B surface antigen secretion in transgenic mice | Q36869563 | ||
Hepatic stem cells and transforming growth factor β in hepatocellular carcinoma | Q37099380 | ||
Viral hepatocarcinogenesis: from infection to cancer | Q34587991 | ||
Hepatitis B surface antigen gene expression is regulated by sex steroids and glucocorticoids in transgenic mice | Q34599361 | ||
Genetic mechanisms of hepatocarcinogenesis | Q34611410 | ||
Hepatocellular carcinoma: insight from animal models | Q34633249 | ||
MicroRNAs in liver cancer: a model for investigating pathogenesis and novel therapeutic approaches. | Q34675280 | ||
Tumor suppressor gene-based nanotherapy: from test tube to the clinic | Q34730883 | ||
Targeting Hepatitis B Virus With CRISPR/Cas9. | Q34745348 | ||
Regulatory elements of hepatitis B virus transcription | Q34842064 | ||
Autophagy suppresses tumorigenesis of hepatitis B virus-associated hepatocellular carcinoma through degradation of microRNA-224. | Q34984034 | ||
The regulation of inflammation by galectin-3. | Q34991925 | ||
Pre-S2 deletion mutants of hepatitis B virus could have an important role in hepatocarcinogenesis in Asian children. | Q35000423 | ||
Nijmegen breakage syndrome gene, NBS1, and molecular links to factors for genome stability | Q35026390 | ||
Overexpression of TRIM24 is associated with the onset and progress of human hepatocellular carcinoma | Q35084843 | ||
NF-κB addiction and its role in cancer: 'one size does not fit all'. | Q35120893 | ||
Carcinogen-induced hepatic tumors in KLF6+/- mice recapitulate aggressive human hepatocellular carcinoma associated with p53 pathway deregulation. | Q35131908 | ||
Parkin is a lipid-responsive regulator of fat uptake in mice and mutant human cells | Q35208410 | ||
Sgo1 is a potential therapeutic target for hepatocellular carcinoma | Q35273343 | ||
NF-κB and STAT3 - key players in liver inflammation and cancer | Q35347976 | ||
Tumor-promoting/progressing role of additional chromosome instability in hepatic carcinogenesis in Sgo1 (Shugoshin 1) haploinsufficient mice | Q35356022 | ||
Deletion of betaine-homocysteine S-methyltransferase in mice perturbs choline and 1-carbon metabolism, resulting in fatty liver and hepatocellular carcinomas | Q35379075 | ||
Whole-genome sequencing identifies recurrent mutations in hepatocellular carcinoma | Q37138658 | ||
Tenets of PTEN tumor suppression | Q37154214 | ||
Pivotal role of mTOR signaling in hepatocellular carcinoma | Q37183244 | ||
Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma | Q37284612 | ||
LKB1; linking cell structure and tumor suppression | Q37333592 | ||
Role of bile acids and bile acid receptors in metabolic regulation | Q37363616 | ||
APC promoter methylation and protein expression in hepatocellular carcinoma | Q37376713 | ||
CYLD: a tumor suppressor deubiquitinase regulating NF-kappaB activation and diverse biological processes | Q37448141 | ||
Comparative PRKAR1A genotype-phenotype analyses in humans with Carney complex and prkar1a haploinsufficient mice | Q37557334 | ||
Then and now: the progress in hepatitis B treatment over the past 20 years | Q37581346 | ||
TGF-β: duality of function between tumor prevention and carcinogenesis. | Q37634488 | ||
Identification of novel oncogenes and tumor suppressors in hepatocellular carcinoma | Q37696402 | ||
The role of signaling pathways in the development and treatment of hepatocellular carcinoma | Q37773788 | ||
Autophagy in liver diseases. | Q37784560 | ||
Haplo-insufficiency: a driving force in cancer | Q37815124 | ||
Biology of Krüppel-like factor 6 transcriptional regulator in cell life and death | Q37820607 | ||
Switching TGFβ from a tumor suppressor to a tumor promoter. | Q37830876 | ||
Hepatitis B therapy | Q37855531 | ||
Genetics of hepatobiliary carcinogenesis | Q37871482 | ||
Molecular diagnosis and therapy of hepatocellular carcinoma (HCC): an emerging field for advanced technologies. | Q37904165 | ||
Bile acids: from digestion to cancers | Q38024178 | ||
gp78: a multifaceted ubiquitin ligase that integrates a unique protein degradation pathway from the endoplasmic reticulum | Q38027564 | ||
Bile acid transporters and regulatory nuclear receptors in the liver and beyond | Q38033967 | ||
p21WAF1 and tumourigenesis: 20 years after | Q38060451 | ||
S-adenosylmethionine metabolism and liver disease. | Q38080431 | ||
Molecular pathways: Jak/STAT pathway: mutations, inhibitors, and resistance | Q38081267 | ||
The mTOR pathway in hepatic malignancies | Q38081396 | ||
The role of autophagy in liver cancer: molecular mechanisms and potential therapeutic targets | Q38083383 | ||
Mouse models for liver cancer. | Q38083387 | ||
Potential role of annexin A7 in cancers | Q38103681 | ||
An Overview of Hepatitis B Virus Surface Antigen Mutant in the Asia Pacific | Q38135400 | ||
Mice with human livers | Q38138332 | ||
Krüppel-like factors in cancer | Q38141516 | ||
An emerging role of PARK2 in cancer | Q38168127 | ||
Molecular targets for cancer therapy in the PI3K/AKT/mTOR pathway | Q38170894 | ||
The role and therapeutic implications of RING-finger E3 ubiquitin ligases in hepatocellular carcinoma | Q38178169 | ||
Molecular insights into NF2/Merlin tumor suppressor function | Q38204110 | ||
Caught up in a Wnt storm: Wnt signaling in cancer | Q29617494 | ||
Epidemiology of viral hepatitis and hepatocellular carcinoma | Q29617918 | ||
Immunology of hepatitis B virus and hepatitis C virus infection | Q29618957 | ||
The Hippo signaling pathway in stem cell biology and cancer | Q30410176 | ||
Characterization of glycine-N-methyltransferase-gene expression in human hepatocellular carcinoma | Q32100816 | ||
Haploinsufficiency of Anx7 tumor suppressor gene and consequent genomic instability promotes tumorigenesis in the Anx7(+/-) mouse | Q33194830 | ||
Correlation between expression of p53, p21/WAF1, and MDM2 proteins and their prognostic significance in primary hepatocellular carcinoma | Q33601430 | ||
Type beta transforming growth factor reversibly inhibits the early proliferative response to partial hepatectomy in the rat. | Q33632161 | ||
Is a function of the secreted hepatitis B e antigen to induce immunologic tolerance in utero? | Q33762446 | ||
In vivo regulation of hepatitis B virus replication by peroxisome proliferators | Q33825523 | ||
Expression and replication of hepatitis B virus genome in transgenic mice | Q33828858 | ||
Nuclear covalently closed circular viral genomic DNA in the liver of hepatocyte nuclear factor 1 alpha-null hepatitis B virus transgenic mice | Q33865967 | ||
Role of Wnt/β-catenin signaling in liver metabolism and cancer | Q33940403 | ||
Late mitotic failure in mice lacking Sak, a polo-like kinase. | Q33942360 | ||
Nf2/Merlin controls progenitor homeostasis and tumorigenesis in the liver | Q34069370 | ||
The Merlin/NF2 tumor suppressor functions through the YAP oncoprotein to regulate tissue homeostasis in mammals | Q34077795 | ||
Nrf2 promotes the development of fibrosis and tumorigenesis in mice with defective hepatic autophagy | Q34086698 | ||
The telomerase inhibitor PinX1 is a major haploinsufficient tumor suppressor essential for chromosome stability in mice | Q34173242 | ||
The ubiquitin-proteasome system: opportunities for therapeutic intervention in solid tumors | Q34218976 | ||
NF-E2-related factor 1 (Nrf1) serves as a novel regulator of hepatic lipid metabolism through regulation of the Lipin1 and PGC-1β genes | Q34274999 | ||
MicroRNA-140 acts as a liver tumor suppressor by controlling NF-κB activity by directly targeting DNA methyltransferase 1 (Dnmt1) expression. | Q34294469 | ||
Complex interactions between microRNAs and hepatitis B/C viruses | Q34302987 | ||
S-adenosylmethionine in liver health, injury, and cancer | Q34306534 | ||
Interleukin-18 inhibits hepatitis B virus replication in the livers of transgenic mice. | Q34350113 | ||
Structural and pathological effects of synthesis of hepatitis B virus large envelope polypeptide in transgenic mice | Q34350664 | ||
The emerging role of hepatitis B virus pre-S2 deletion mutant proteins in HBV tumorigenesis. | Q34354947 | ||
Hepatitis B virus X protein upregulates mTOR signaling through IKKβ to increase cell proliferation and VEGF production in hepatocellular carcinoma | Q34359262 | ||
NAFLD, NASH and liver cancer | Q34374372 | ||
Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas | Q34380511 | ||
Autophagy-preferential degradation of MIR224 participates in hepatocellular carcinoma tumorigenesis | Q34388829 | ||
Autophagy and apoptosis-related genes in chronic liver disease and hepatocellular carcinoma. | Q34396410 | ||
The CRISPR/Cas9 System Facilitates Clearance of the Intrahepatic HBV Templates In Vivo | Q34459390 | ||
Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA level | Q34481474 | ||
Hepatocellular carcinoma caused by loss of heterozygosity in Lkb1 gene knockout mice | Q34526330 | ||
Hippo-YAP signaling pathway: A new paradigm for cancer therapy | Q38231786 | ||
Hepatocellular carcinoma epidemiology | Q38254688 | ||
Hippo pathway regulation of gastrointestinal tissues | Q38257899 | ||
Hepatocellular carcinoma and microRNA: new perspectives on therapeutics and diagnostics | Q38275679 | ||
Shugoshins: tension-sensitive pericentromeric adaptors safeguarding chromosome segregation | Q38276217 | ||
Hepatitis B and D viruses exploit sodium taurocholate co-transporting polypeptide for species-specific entry into hepatocytes. | Q38310253 | ||
The JAK-STAT pathway: impact on human disease and therapeutic intervention | Q38317993 | ||
Identification of the common regulators for hepatocellular carcinoma induced by hepatitis B virus X antigen in a mouse model. | Q38330894 | ||
Hitting cancers' weak spots: vulnerabilities imposed by p53 mutation | Q38470609 | ||
Incidence of hepatocellular carcinoma in transgenic mice expressing the hepatitis B virus X-protein | Q38527672 | ||
miR-375 inhibits autophagy and reduces viability of hepatocellular carcinoma cells under hypoxic conditions | Q39364639 | ||
The molecular biology of the hepatitis B viruses | Q39511089 | ||
Association of autophagy defect with a malignant phenotype and poor prognosis of hepatocellular carcinoma | Q39916459 | ||
Disruption of transforming growth factor-beta signaling through beta-spectrin ELF leads to hepatocellular cancer through cyclin D1 activation | Q40124427 | ||
Replication and gene expression of hepatitis B virus in a transgenic mouse that contains the complete viral genome | Q40130886 | ||
Reduced expression of CYLD in human colon and hepatocellular carcinomas | Q40267883 | ||
Hepatitis B virus pre-S2 mutant upregulates cyclin A expression and induces nodular proliferation of hepatocytes. | Q40455477 | ||
Parkin gene alterations in hepatocellular carcinoma | Q40564245 | ||
A transgenic mouse model of the chronic hepatitis B surface antigen carrier state | Q41483768 | ||
A biphasic response pattern of lipid metabolomics in the stage progression of hepatitis B virus X tumorigenesis | Q41540811 | ||
Suppression of hepatitis B virus DNA accumulation in chronically infected cells using a bacterial CRISPR/Cas RNA-guided DNA endonuclease | Q41566723 | ||
Immunobiology and pathogenesis of hepatocellular injury in hepatitis B virus transgenic mice | Q41736950 | ||
Molecular pathogenesis of hepatocellular carcinoma in hepatitis B virus transgenic mice | Q41757834 | ||
Autophagy-deficient mice develop multiple liver tumors | Q42099409 | ||
A quantitative proteomic approach for identification of potential biomarkers in hepatocellular carcinoma | Q42594913 | ||
Resveratrol helps recovery from fatty liver and protects against hepatocellular carcinoma induced by hepatitis B virus X protein in a mouse model | Q42717718 | ||
Liver damage, inflammation, and enhanced tumorigenesis after persistent mTORC1 inhibition | Q42718504 | ||
Parkin as a tumor suppressor gene for hepatocellular carcinoma | Q42811415 | ||
Expression and prognostic role of tumor suppressor gene PTEN/MMAC1/TEP1 in hepatocellular carcinoma | Q43049041 | ||
Hepatitis B injury, male gender, aflatoxin, and p53 expression each contribute to hepatocarcinogenesis in transgenic mice | Q43601327 | ||
Hepatocarcinogenesis due to chronic liver cell injury in hepatitis B virus transgenic mice | Q44184480 | ||
Thirty-year outcomes of the national hepatitis B immunization program in Taiwan | Q44712948 | ||
Production and effect of infectious Dane particles in transgenic mice | Q44984147 | ||
Blocking of G1/S transition and cell death in the regenerating liver of Hepatitis B virus X protein transgenic mice | Q45420975 | ||
The hepatitis B virus-trimera mouse: a model for human HBV infection and evaluation of anti-HBV therapeutic agents. | Q45751631 | ||
High-level expression of hepatitis B virus HBx gene and hepatocarcinogenesis in transgenic mice | Q45779177 | ||
Hepatic preneoplasia in hepatitis B virus transgenic mice | Q45782995 | ||
HBx gene of hepatitis B virus induces liver cancer in transgenic mice | Q45852802 | ||
Characterization of T-cell tolerance to hepatitis B virus (HBV) antigen in transgenic mice | Q45868334 | ||
IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages | Q46376203 | ||
Expression of galectin-3 involved in prognosis of patients with hepatocellular carcinoma | Q46442908 | ||
Metabolic factors and risk of hepatocellular carcinoma by chronic hepatitis B/C infection: a follow-up study in Taiwan. | Q46573520 | ||
Chemopreventive effect of silymarin on liver pathology in HBV X protein transgenic mice | Q46702642 | ||
Transforming growth factor-beta1 is a new form of tumor suppressor with true haploid insufficiency. | Q47852627 | ||
Steatohepatitis, spontaneous peroxisome proliferation and liver tumors in mice lacking peroxisomal fatty acyl-CoA oxidase. Implications for peroxisome proliferator-activated receptor alpha natural ligand metabolism | Q47982118 | ||
Estrogen-sensitive PTPRO expression represses hepatocellular carcinoma progression by control of STAT3. | Q51323736 | ||
Disrupted galectin-3 causes non-alcoholic fatty liver disease in male mice. | Q52574179 | ||
Disruption of Trp53 in livers of mice induces formation of carcinomas with bilineal differentiation. | Q52621794 | ||
p21 ablation in liver enhances DNA damage, cholestasis, and carcinogenesis. | Q53224670 | ||
TRIM proteins and cancer. | Q53280723 | ||
TAK1 suppresses a NEMO-dependent but NF-kappaB-independent pathway to liver cancer. | Q53299056 | ||
Nonalcoholic steatohepatitis and hepatocellular carcinoma in galectin-3 knockout mice. | Q53319230 | ||
Deletion of the SOCS3 gene in liver parenchymal cells promotes hepatitis-induced hepatocarcinogenesis. | Q53344106 | ||
Plk4 haploinsufficiency causes mitotic infidelity and carcinogenesis. | Q53356205 | ||
HBsAg and HBx knocked into the p21 locus causes hepatocellular carcinoma in mice. | Q53370903 | ||
p21Cip1 nullizygosity increases tumor metastasis in irradiated mice. | Q53378608 | ||
Constitutive activation of NF-kappaB in human hepatocellular carcinoma: evidence of a cytoprotective role. | Q53631902 | ||
Inactivation of the deubiquitinase CYLD in hepatocytes causes apoptosis, inflammation, fibrosis, and cancer. | Q54305213 | ||
Hepatobiliary transporter expression in human hepatocellular carcinoma. | Q54674953 | ||
Oncogenic and tumor suppressive roles of polo-like kinases in human hepatocellular carcinoma. | Q54695730 | ||
Hepatocellular carcinoma development induced by conditional beta-catenin activation in Lkb1+/- mice. | Q54727263 | ||
Mutational and expressional analyses of ATG5, an autophagy-related gene, in gastrointestinal cancers. | Q55054516 | ||
High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice | Q58378937 | ||
Deletion of NEMO/IKKγ in Liver Parenchymal Cells Causes Steatohepatitis and Hepatocellular Carcinoma | Q58619568 | ||
Sh(i)pping signals protect against Stat3-driven liver cancer | Q59198940 | ||
Specific expression of hepatitis B surface antigen (HBsAg) in transgenic mice | Q59890897 | ||
Sh(i)pping signals protect against Stat3-driven liver cancer | Q62176883 | ||
Reduced mRNA abundance of the main enzymes involved in methionine metabolism in human liver cirrhosis and hepatocellular carcinoma | Q62727088 | ||
HBV production in transgenic mice | Q68582773 | ||
Extrathymic expression of the intracellular hepatitis B core antigen results in T cell tolerance in transgenic mice | Q72712084 | ||
Expression of p27(KIP1) and p21(WAF1/CIP1) in primary hepatocellular carcinoma: clinicopathologic correlation and survival analysis | Q74421318 | ||
Molecular pathogenesis of human hepatocellular carcinoma | Q74543031 | ||
Transforming growth factor betas and their signaling receptors in human hepatocellular carcinoma | Q77373481 | ||
Analysis of transforming growth factor (TGF)-alpha/epidermal growth factor receptor, hepatocyte growth Factor/c-met,TGF-beta receptor type II, and p53 expression in human hepatocellular carcinomas | Q77554578 | ||
ANXA7 expression represents hormone-relevant tumor suppression in different cancers | Q80817271 | ||
NEMO expression in human hepatocellular carcinoma and its association with clinical outcome | Q82999544 | ||
Genomic instability and cancer: an introduction | Q83325039 | ||
The cell cycle and cancer | Q85077091 | ||
P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | haploinsufficiency | Q852654 |
hepatocellular carcinoma | Q1148337 | ||
Hepatitis B virus | Q6844 | ||
virology | Q7215 | ||
P304 | page(s) | 300-325 | |
P577 | publication date | 2016-01-01 | |
P1433 | published in | World Journal of Gastroenterology | Q15708885 |
P1476 | title | Hepatocellular carcinoma mouse models: Hepatitis B virus-associated hepatocarcinogenesis and haploinsufficient tumor suppressor genes | |
P478 | volume | 22 |
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