scholarly article | Q13442814 |
P2093 | author name string | Nigel Irwin | |
Peter R Flatt | |||
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Oxyntomodulin suppresses appetite and reduces food intake in humans | Q79161514 | ||
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Liraglutide, the glucagon-like peptide-1 receptor agonist, has anabolic bone effects in diabetic Goto-Kakizaki rats | Q86891278 | ||
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Metabolic effects of activation of CCK receptor signaling pathways by twice-daily administration of the enzyme-resistant CCK-8 analog, (pGlu-Gln)-CCK-8, in normal mice | Q87427418 | ||
DPP IV inhibitor treatment attenuates bone loss and improves mechanical bone strength in male diabetic rats | Q87428531 | ||
Double incretin receptor knock-out (DIRKO) mice present with alterations of trabecular and cortical micromorphology and bone strength | Q87587380 | ||
Marked expansion of exocrine and endocrine pancreas with incretin therapy in humans with increased exocrine pancreas dysplasia and the potential for glucagon-producing neuroendocrine tumors | Q24598747 | ||
New drug treatments show neuroprotective effects in Alzheimer's and Parkinson's diseases | Q26866194 | ||
Unraveling oxyntomodulin, GLP1's enigmatic brother | Q27001704 | ||
Pharmacology, physiology, and mechanisms of incretin hormone action | Q27021545 | ||
Osteoblast-derived cells express functional glucose-dependent insulinotropic peptide receptors | Q28145693 | ||
Dipeptidyl peptidase-4 inhibitors and cardiovascular outcomes: meta-analysis of randomized clinical trials with 55,141 participants | Q28238585 | ||
Gastric inhibitory polypeptide receptor, a member of the secretin-vasoactive intestinal peptide receptor family, is widely distributed in peripheral organs and the brain | Q28256443 | ||
Evaluation of the degradation and metabolic effects of the gut peptide xenin on insulin secretion, glycaemic control and satiety | Q28287902 | ||
GLP-1/GIP chimeric peptides define the structural requirements for specific ligand-receptor interaction of GLP-1 | Q28289025 | ||
Optimal bone mechanical and material properties require a functional glucagon-like peptide-1 receptor | Q28295907 | ||
Effects of glucose-dependent insulinotropic peptide on behavior | Q28504780 | ||
Protease-resistant glucose-dependent insulinotropic polypeptide agonists facilitate hippocampal LTP and reverse the impairment of LTP induced by beta-amyloid | Q28565656 | ||
Cardiac function in mice lacking the glucagon-like peptide-1 receptor | Q28586718 | ||
Cholecystokinin receptors | Q28608935 | ||
Effects of beta-cell rest on beta-cell function: a review of clinical and preclinical data | Q31144148 | ||
Glucose-dependent insulinotropic polypeptide is expressed in pancreatic islet alpha-cells and promotes insulin secretion | Q33529942 | ||
Incretin receptor null mice reveal key role of GLP-1 but not GIP in pancreatic beta cell adaptation to pregnancy | Q33753169 | ||
Role of endogenous GLP-1 and GIP in beta cell compensatory responses to insulin resistance and cellular stress | Q33812543 | ||
Effects of exenatide and lifestyle modification on body weight and glucose tolerance in obese subjects with and without pre-diabetes | Q33873009 | ||
Xenin-25 potentiates glucose-dependent insulinotropic polypeptide action via a novel cholinergic relay mechanism | Q33924273 | ||
Receptors and effects of gut hormones in three osteoblastic cell lines | Q33975451 | ||
The effect of DPP-4 inhibition with sitagliptin on incretin secretion and on fasting and postprandial glucose turnover in subjects with impaired fasting glucose | Q34014522 | ||
Cholecystokinin | Q34096294 | ||
Cholecystokinin is up-regulated in obese mouse islets and expands beta-cell mass by increasing beta-cell survival | Q34132510 | ||
Glucose-dependent insulinotropic polypeptide receptor deficiency leads to modifications of trabecular bone volume and quality in mice | Q34316123 | ||
Glucose-dependent insulinotropic polypeptide (GIP) receptor deletion leads to reduced bone strength and quality. | Q34357351 | ||
A meta-analysis of serious adverse events reported with exenatide and liraglutide: acute pancreatitis and cancer. | Q34421364 | ||
Proglucagon-derived peptides: mechanisms of action and therapeutic potential | Q34452524 | ||
The murine glucagon-like peptide-1 receptor is essential for control of bone resorption. | Q34585388 | ||
Gastrointestinal regulation of food intake | Q35251043 | ||
Glucose-dependent insulinotropic polypeptide (GIP): anti-diabetic and anti-obesity potential? | Q35579570 | ||
Glucose-dependent insulinotropic polypeptide inhibits bone resorption in humans | Q42464329 | ||
Deciphering metabolic messages from the gut drives therapeutic innovation: the 2014 Banting Lecture | Q42471846 | ||
Beneficial effects of a N-terminally modified GIP agonist on tissue-level bone material properties | Q42805863 | ||
Effects of liraglutide in the treatment of obesity: a randomised, double-blind, placebo-controlled study | Q43255700 | ||
Effects of chronic exposure of clonal β-cells to elevated glucose and free fatty acids on incretin receptor gene expression and secretory responses to GIP and GLP-1. | Q43651347 | ||
Glucagon-like peptide-1 increases cAMP but fails to augment contraction in adult rat cardiac myocytes | Q43726354 | ||
Effects of cholecystokinin (CCK)-8, CCK-33, and gastric inhibitory polypeptide (GIP) on basal and meal-stimulated pancreatic hormone secretion in man | Q43947295 | ||
The novel GLP-1-gastrin dual agonist, ZP3022, increases β-cell mass and prevents diabetes in db/db mice | Q44704405 | ||
Induction of beta-cell rest by a Kir6.2/SUR1-selective K(ATP)-channel opener preserves beta-cell insulin stores and insulin secretion in human islets cultured at high (11 mM) glucose | Q44757149 | ||
Sulfonylurea induced beta-cell apoptosis in cultured human islets | Q45105959 | ||
Xenin-25[Lys13PAL]: a novel long-acting acylated analogue of xenin-25 with promising antidiabetic potential | Q45378064 | ||
Beneficial effects of (pGlu-Gln)-CCK-8 on energy intake and metabolism in high fat fed mice are associated with alterations of hypothalamic gene expression | Q45796873 | ||
Use of dipeptidyl peptidase-4 inhibitors for type 2 diabetes mellitus and risk of fracture. | Q45918551 | ||
Design of a long acting peptide functioning as both a glucagon-like peptide-1 receptor agonist and a glucagon receptor antagonist | Q46131933 | ||
Antidiabetic effects of sub-chronic activation of the GIP receptor alone and in combination with background exendin-4 therapy in high fat fed mice | Q46203073 | ||
KATP channel closure ameliorates the impaired insulinotropic effect of glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes | Q46218694 | ||
Four weeks of near-normalisation of blood glucose improves the insulin response to glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes | Q46226028 | ||
Dorothy Hodgkin Lecture 2008. Gastric inhibitory polypeptide (GIP) revisited: a new therapeutic target for obesity-diabetes? | Q46567054 | ||
Subcutaneous oxyntomodulin reduces body weight in overweight and obese subjects: a double-blind, randomized, controlled trial | Q46620662 | ||
Insulin sensitivity, insulin release and glucagon-like peptide-1 levels in persons with impaired fasting glucose and/or impaired glucose tolerance in the EUGENE2 study | Q46850405 | ||
Effects of the dipeptidyl peptidase-IV inhibitor vildagliptin on incretin hormones, islet function, and postprandial glycemia in subjects with impaired glucose tolerance | Q46942344 | ||
The dipeptidyl peptidase-4 inhibitor vildagliptin improves beta-cell function and insulin sensitivity in subjects with impaired fasting glucose | Q46972113 | ||
Glucose-dependent insulinotropic peptide: differential effects on hepatic artery vs. portal vein endothelial cells | Q47280771 | ||
A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents | Q48246762 | ||
Impairment of synaptic plasticity and memory formation in GLP-1 receptor KO mice: Interaction between type 2 diabetes and Alzheimer's disease | Q48270990 | ||
Sitagliptin, a dipeptidyl peptidase-4 inhibitor, improves recognition memory, oxidative stress and hippocampal neurogenesis and upregulates key genes involved in cognitive decline | Q48379621 | ||
Restoration of cerebral and systemic microvascular architecture in APP/PS1 transgenic mice following treatment with Liraglutide™. | Q48392292 | ||
Sequential induction of beta cell rest and stimulation using stable GIP inhibitor and GLP-1 mimetic peptides improves metabolic control in C57BL/KsJ db/db mice. | Q35655010 | ||
Physiology of incretins in health and disease | Q35760279 | ||
Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus | Q35824086 | ||
Glucagon like peptide-1 receptor expression in the human thyroid gland | Q36141532 | ||
Emerging DPP-4 inhibitors: focus on linagliptin for type 2 diabetes | Q36520758 | ||
Gut hormones and appetite control | Q36820186 | ||
Combination therapy with GLP-1 receptor agonists and basal insulin: a systematic review of the literature | Q36872178 | ||
A critical analysis of the clinical use of incretin-based therapies: Are the GLP-1 therapies safe? | Q36942123 | ||
Evidence for beneficial effects of compromised gastric inhibitory polypeptide action in obesity-related diabetes and possible therapeutic implications. | Q37521930 | ||
The role of gut hormones in the regulation of body weight and energy homeostasis | Q37535112 | ||
Do GLP-1-based therapies increase cancer risk? | Q37577143 | ||
Therapeutic potential of the original incretin hormone glucose-dependent insulinotropic polypeptide: diabetes, obesity, osteoporosis and Alzheimer's disease? | Q37779101 | ||
The safety and tolerability of GLP-1 receptor agonists in the treatment of type 2 diabetes: a review | Q37864256 | ||
The gut endocrine system as a coordinator of postprandial nutrient homoeostasis | Q38036016 | ||
A network meta-analysis to compare glycaemic control in patients with type 2 diabetes treated with exenatide once weekly or liraglutide once daily in comparison with insulin glargine, exenatide twice daily or placebo. | Q38041660 | ||
Enteroendocrine hormone mimetics for the treatment of obesity and diabetes | Q38142518 | ||
The role of incretin-based therapies in prediabetes: a review | Q38199251 | ||
Cardiovascular actions of GLP-1 and incretin-based pharmacotherapy. | Q38199984 | ||
Glucagon-like peptide-1 receptor agonists for the treatment of type 2 diabetes: differences and similarities. | Q38201586 | ||
Gastrointestinal hormones and their targets | Q38226510 | ||
Risk of bone fractures associated with glucagon-like peptide-1 receptor agonists' treatment: a meta-analysis of randomized controlled trials | Q38235219 | ||
Pharmacological characterization and antidiabetic activity of a long-acting glucagon-like peptide-1 analogue conjugated to an antithrombin III-binding pentasaccharide. | Q38299362 | ||
Synergistic metabolic benefits of an exenatide analogue and cholecystokinin in diet-induced obese and leptin-deficient rodents | Q38304318 | ||
Chemical cholecystokinin receptor activation protects against obesity-diabetes in high fat fed mice and has sustainable beneficial effects in genetic ob/ob mice. | Q38320627 | ||
Degradation, insulin secretion, glucose-lowering and GIP additive actions of a palmitate-derivatised analogue of xenin-25. | Q38325630 | ||
Studying pancreatic risks caused by incretin-based therapies: is it a game? It's not a game! | Q38601929 | ||
A novel GIP-oxyntomodulin hybrid peptide acting through GIP, glucagon and GLP-1 receptors exhibits weight reducing and anti-diabetic properties | Q39177528 | ||
Comparison of independent and combined metabolic effects of chronic treatment with (pGlu-Gln)-CCK-8 and long-acting GLP-1 and GIP mimetics in high fat-fed mice | Q39198588 | ||
Processing of proglucagon to GLP-1 in pancreatic α-cells: is this a paracrine mechanism enabling GLP-1 to act on β-cells? | Q39499843 | ||
(D-Ser2)Oxm[mPEG-PAL]: a novel chemically modified analogue of oxyntomodulin with antihyperglycaemic, insulinotropic and anorexigenic actions | Q39663862 | ||
Glucagon-like Peptide-1 receptor agonists activate rodent thyroid C-cells causing calcitonin release and C-cell proliferation. | Q39732229 | ||
Glucose intolerance and reduced proliferation of pancreatic beta-cells in transgenic pigs with impaired glucose-dependent insulinotropic polypeptide function | Q40132400 | ||
Plasma Insulin Responses to Oral and Intravenous Glucose: Studies in Normal and Diabetic Subjects* | Q40329405 | ||
Glucose-dependent insulinotropic polypeptide (GIP) stimulation of pancreatic beta-cell survival is dependent upon phosphatidylinositol 3-kinase (PI3K)/protein kinase B (PKB) signaling, inactivation of the forkhead transcription factor Foxo1, and dow | Q40437409 | ||
Glucose-dependent insulinotropic polypeptide promotes beta-(INS-1) cell survival via cyclic adenosine monophosphate-mediated caspase-3 inhibition and regulation of p38 mitogen-activated protein kinase. | Q40637074 | ||
Functional GIP receptors play a major role in islet compensatory response to high fat feeding in mice | Q41420211 | ||
Mechanism of metabolic advantages after bariatric surgery: it's all gastrointestinal factors versus it's all food restriction. | Q41945986 | ||
Glucagon-like peptide 1/glucagon receptor dual agonism reverses obesity in mice | Q41982493 | ||
GLP-1R agonist liraglutide activates cytoprotective pathways and improves outcomes after experimental myocardial infarction in mice | Q41984767 | ||
Coinfusion of low-dose GLP-1 and glucagon in man results in a reduction in food intake | Q42210115 | ||
P433 | issue | 15 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 1285-95 | |
P577 | publication date | 2015-11-10 | |
P1433 | published in | World journal of diabetes | Q27723539 |
P1476 | title | New perspectives on exploitation of incretin peptides for the treatment of diabetes and related disorders | |
P478 | volume | 6 |
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