Impairment of synaptic plasticity and memory formation in GLP-1 receptor KO mice: Interaction between type 2 diabetes and Alzheimer's disease

scientific article published on 30 June 2009

Impairment of synaptic plasticity and memory formation in GLP-1 receptor KO mice: Interaction between type 2 diabetes and Alzheimer's disease is …
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scholarly articleQ13442814

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P356DOI10.1016/J.BBR.2009.06.035
P698PubMed publication ID19573562
P5875ResearchGate publication ID223519026

P50authorChristian HölscherQ37831053
P2093author name stringEmilie Faivre
Talib Abbas
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectAlzheimer's diseaseQ11081
memory formationQ107596539
synaptic plasticityQ1551556
type 2 diabetesQ3025883
P304page(s)265-271
P577publication date2009-06-30
P1433published inBehavioural Brain ResearchQ3619047
P1476titleImpairment of synaptic plasticity and memory formation in GLP-1 receptor KO mice: Interaction between type 2 diabetes and Alzheimer's disease
P478volume205

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cites work (P2860)
Q49113854A nutrigenomics approach for the study of anti-aging interventions: olive oil phenols and the modulation of gene and microRNA expression profiles in mouse brain
Q48254911Actions of exendin-4 therapy on cognitive function and hippocampal synaptic plasticity in mice fed a high-fat diet
Q99404602Alleviation of Depression by Glucagon-Like Peptide 1 Through the Regulation of Neuroinflammation, Neurotransmitters, Neurogenesis, and Synaptic Function
Q26996487Alzheimer's disease and insulin resistance: translating basic science into clinical applications
Q50746082Berberine chloride improved synaptic plasticity in STZ induced diabetic rats.
Q34884241Bidirectional metabolic regulation of neurocognitive function
Q34639384Chronic treatment with the GLP1 analogue liraglutide increases cell proliferation and differentiation into neurons in an AD mouse model
Q99709166Clinical Evidence of Antidepressant Effects of Insulin and Anti-Hyperglycemic Agents and Implications for the Pathophysiology of Depression-A Literature Review
Q48178356DPP4 Inhibitors Can Be a Drug of Choice for Type 3 Diabetes: A Mini Review
Q53447397Decreased glucagon-like peptide-1 receptor immunoreactivity in the dentate granule cell layer from adult in the gerbil hippocampus.
Q35532253Drp1-mediated mitochondrial abnormalities link to synaptic injury in diabetes model
Q52151966Early intervention with glucagon-like peptide 1 analog liraglutide prevents tau hyperphosphorylation in diabetic db/db mice.
Q92042716Effects of GLP-1 Receptor Activation on a Pentylenetetrazole-Kindling Rat Model
Q92005722Effects of glucagon-like peptide 1 receptor agonists on comorbidities in older patients with diabetes mellitus
Q28710367Energy intake and exercise as determinants of brain health and vulnerability to injury and disease
Q51362307Evaluation of the long-term effects of gastric inhibitory polypeptide-ovalbumin conjugates on insulin resistance, metabolic dysfunction, energy balance and cognition in high-fat-fed mice.
Q48864779Exenatide enhances cognitive performance and upregulates neurotrophic factor gene expression levels in diabetic mice
Q33708923Exendin-4 Treatment Improves LPS-Induced Depressive-Like Behavior Without Affecting Pro-Inflammatory Cytokines
Q28481242Exendin-4 ameliorates motor neuron degeneration in cellular and animal models of amyotrophic lateral sclerosis
Q48422656Exendin-4, a glucagon-like peptide-1 receptor agonist, reduces Alzheimer disease-associated tau hyperphosphorylation in the hippocampus of rats with type 2 diabetes
Q34745109Expression and distribution of glucagon-like peptide-1 receptor mRNA, protein and binding in the male nonhuman primate (Macaca mulatta) brain.
Q34395967Fertility and pregnancy-associated ß-cell proliferation in mice deficient in proglucagon-derived peptides
Q33609502GIP and GLP-1, the two incretin hormones: Similarities and differences
Q35200252GLP-1 based therapeutics: simultaneously combating T2DM and obesity.
Q34167980GLP-1 receptor stimulation reduces amyloid-beta peptide accumulation and cytotoxicity in cellular and animal models of Alzheimer's disease.
Q26997149GLP-1-based strategies: a physiological analysis of differential mode of action
Q37349843Glucagon-like peptide 1 receptor activation regulates cocaine actions and dopamine homeostasis in the lateral septum by decreasing arachidonic acid levels.
Q38868456Glucagon-like peptide-1 drives energy metabolism on the synaptic highway
Q35070673Glucagon-like peptide-1, diabetes, and cognitive decline: possible pathophysiological links and therapeutic opportunities.
Q33603384Glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1: Incretin actions beyond the pancreas
Q51021916Glucose-dependent insulinotropic polypeptide receptor knockout mice are impaired in learning, synaptic plasticity, and neurogenesis.
Q37540256Humans with Type-2 Diabetes Show Abnormal Long-Term Potentiation-Like Cortical Plasticity Associated with Verbal Learning Deficits
Q58608318Impact of rye-based evening meals on cognitive functions, mood and cardiometabolic risk factors: a randomized controlled study in healthy middle-aged subjects
Q37894864Incretin-based therapies
Q27008997Insulin resistance as a key link for the increased risk of cognitive impairment in the metabolic syndrome
Q47102484Interactions between metabolic, reward and cognitive processes in appetite control: Implications for novel weight management therapies.
Q48488584Linagliptin, a Dipeptidyl Peptidase-4 Inhibitor, Mitigates Cognitive Deficits and Pathology in the 3xTg-AD Mouse Model of Alzheimer's Disease.
Q26860246Link between type 2 diabetes and Alzheimer's disease: from epidemiology to mechanism and treatment
Q38324750Liraglutide improves hippocampal synaptic plasticity associated with increased expression of Mash1 in ob/ob mice.
Q47107585Liraglutide restores chronic ER stress, autophagy impairments and apoptotic signalling in SH-SY5Y cells
Q35007766Long-Term Potentiation at CA3-CA1 Hippocampal Synapses with Special Emphasis on Aging, Disease, and Stress
Q24562763Metabolic dysfunction in Alzheimer's disease and related neurodegenerative disorders
Q42098016Microbiota modulation counteracts Alzheimer's disease progression influencing neuronal proteolysis and gut hormones plasma levels.
Q38974881Modulation of GLP-1 signaling as a novel therapeutic approach in the treatment of Alzheimer's disease pathology
Q35568177Modulation of hippocampal neural plasticity by glucose-related signaling
Q48061475Neurochemical modulation involved in the beneficial effect of liraglutide, GLP-1 agonist on PTZ kindling epilepsy-induced comorbidities in mice
Q90236862Neuroprotective Actions of Glucagon-Like Peptide-1 (GLP-1) Analogues in Alzheimer's and Parkinson's Diseases
Q48358888Neuroprotective actions of glucagon-like peptide-1 in differentiated human neuroprogenitor cells
Q36166654Neuroprotective and neurotrophic actions of glucagon-like peptide-1: an emerging opportunity to treat neurodegenerative and cerebrovascular disorders
Q26777654New perspectives on exploitation of incretin peptides for the treatment of diabetes and related disorders
Q38668948Novel GLP-1 (Glucagon-Like Peptide-1) Analogues and Insulin in the Treatment for Alzheimer's Disease and Other Neurodegenerative Diseases
Q41986529Obesity as a risk factor for Alzheimer's disease: weighing the evidence
Q34290086Obesity-Related Hormones in Low-Income Preschool-Age Children: Implications for School Readiness
Q35558707Obesity-associated biomarkers and executive function in children
Q36339320PPG neurons of the lower brain stem and their role in brain GLP-1 receptor activation.
Q59812434Pleiotropic Effects of GLP-1 and Analogs on Cell Signaling, Metabolism, and Function
Q38926789Potential effects of current drug therapies on cognitive impairment in patients with type 2 diabetes
Q26774021Potentials of incretin-based therapies in dementia and stroke in type 2 diabetes mellitus
Q47266756Presynaptic GLP-1 receptors enhance the depolarization-evoked release of glutamate and GABA in the mouse cortex and hippocampus
Q64102382Regulation of Memory Function by Feeding-Relevant Biological Systems: Following the Breadcrumbs to the Hippocampus
Q41636096RhGLP-1 (7-36) protects diabetic rats against cerebral ischemia-reperfusion injury via up-regulating expression of Nrf2/HO-1 and increasing the activities of SOD.
Q28083039Role of anti-diabetic drugs as therapeutic agents in Alzheimer's disease
Q26824141Running forward: new frontiers in endurance exercise biology
Q48379621Sitagliptin, a dipeptidyl peptidase-4 inhibitor, improves recognition memory, oxidative stress and hippocampal neurogenesis and upregulates key genes involved in cognitive decline
Q37685201Subcutaneous liraglutide ameliorates methylglyoxal-induced Alzheimer-like tau pathology and cognitive impairment by modulating tau hyperphosphorylation and glycogen synthase kinase-3β
Q35738734Synergistic exacerbation of mitochondrial and synaptic dysfunction and resultant learning and memory deficit in a mouse model of diabetic Alzheimer's disease
Q37900307Targeting amyloid-beta by glucagon-like peptide -1 (GLP-1) in Alzheimer's disease and diabetes
Q37811420The Role of GLP-1 in Neuronal Activity and Neurodegeneration
Q47111896The Role of Glucagon-Like Peptide 1 (GLP1) in Type 3 Diabetes: GLP-1 Controls Insulin Resistance, Neuroinflammation and Neurogenesis in the Brain
Q42715682The diabetes drug liraglutide ameliorates aberrant insulin receptor localisation and signalling in parallel with decreasing both amyloid-β plaque and glial pathology in a mouse model of Alzheimer's disease.
Q51011184The diabetes drug liraglutide prevents degenerative processes in a mouse model of Alzheimer's disease.
Q50050282The diabetes drug liraglutide reverses cognitive impairment in mice and attenuates insulin receptor and synaptic pathology in a non-human primate model of Alzheimer's disease.
Q26768527The glucagon-like peptide 1 (GLP) receptor as a therapeutic target in Parkinson's disease: mechanisms of action
Q33868403The impact of dietary energy intake on cognitive aging
Q37830311The role of G protein-coupled receptors in the pathology of Alzheimer's disease
Q35199055Treadmill exercise prevents diabetes-induced increases in lipid peroxidation and decreases in Cu,Zn-superoxide dismutase levels in the hippocampus of Zucker diabetic fatty rats
Q95643642Type 2 diabetes and cognitive dysfunction-towards effective management of both comorbidities
Q30494084Uncovering molecular biomarkers that correlate cognitive decline with the changes of hippocampus' gene expression profiles in Alzheimer's disease
Q53427297[Diabetes mellitus and cognitive decline].

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