Three-Dimensional Environment Sustains Hematopoietic Stem Cell Differentiation into Platelet-Producing Megakaryocytes

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Three-Dimensional Environment Sustains Hematopoietic Stem Cell Differentiation into Platelet-Producing Megakaryocytes is …
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scholarly articleQ13442814

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P819ADS bibcode2015PLoSO..1036652P
P356DOI10.1371/JOURNAL.PONE.0136652
P932PMC publication ID4552162
P698PubMed publication ID26313154
P5875ResearchGate publication ID281552250

P50authorDidier LetourneurQ38545565
Alexandre KauskotQ39272199
Catherine Le VisageQ40243127
Dominique BaruchQ57244699
Sophie GandrilleQ57948386
Sidi Mohammed DerkaouiQ123418018
P2093author name stringSonia Poirault-Chassac
Audrey Pietrzyk-Nivau
P2860cites workAnalysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT MethodQ25938999
Transcription factors in late megakaryopoiesis and related platelet disordersQ27015841
Pluripotent stem cells reveal the developmental biology of human megakaryocytes and provide a source of platelets for clinical applicationQ27026899
Bone marrow osteoblastic niche: a new model to study physiological regulation of megakaryopoiesisQ28472310
Ligand density dramatically affects integrin alpha IIb beta 3-mediated platelet signaling and spreadingQ30479586
Chemokine-mediated interaction of hematopoietic progenitors with the bone marrow vascular niche is required for thrombopoiesisQ33358404
Transient activation of c-MYC expression is critical for efficient platelet generation from human induced pluripotent stem cellsQ33392928
Expandable megakaryocyte cell lines enable clinically applicable generation of platelets from human induced pluripotent stem cellsQ33413336
Polyploidy: occurrence in nature, mechanisms, and significance for the megakaryocyte-platelet systemQ33829619
The incredible journey: From megakaryocyte development to platelet formation.Q34037117
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Notch1 regulates progenitor cell proliferation and differentiation during mouse yolk sac hematopoiesisQ34393771
Transcription factor networks in erythroid cell and megakaryocyte developmentQ35112203
Hematopoietic stem cells: from the bone to the bioreactorQ35119691
Three-dimensional system for the in vitro study of megakaryocytes and functional platelet production using silk-based vascular tubesQ35579676
Extracellular matrix structure and nano-mechanics determine megakaryocyte function.Q35794111
Thrombopoietin and the hematopoietic stem cellQ36164512
Mesenchymal stem cell delivery into rat infarcted myocardium using a porous polysaccharide-based scaffold: a quantitative comparison with endocardial injectionQ36765397
From hematopoietic stem cells to platelets.Q36884453
Sources of heterogeneity in human monocyte subsetsQ36935158
Uncertainty in the niches that maintain haematopoietic stem cellsQ37103620
In vitro megakaryocyte production and platelet biogenesis: state of the artQ37644828
Notch signaling specifies megakaryocyte development from hematopoietic stem cells.Q37673550
Megakaryocyte and platelet production from human cord blood stem cellsQ37963241
Fucoidan promotes early step of cardiac differentiation from human embryonic stem cells and long-term maintenance of beating areas.Q38846480
Biogenesis of the demarcation membrane system (DMS) in megakaryocytesQ39327416
RUNX1-induced silencing of non-muscle myosin heavy chain IIB contributes to megakaryocyte polyploidizationQ39384298
A common bipotent progenitor generates the erythroid and megakaryocyte lineages in embryonic stem cell-derived primitive hematopoiesis.Q39845785
Stem cell factor.Q40402672
Biomimetic three-dimensional cultures significantly increase hematopoietic differentiation efficacy of embryonic stem cells.Q40452528
Mechanisms of actin rearrangements mediating platelet activationQ42087428
Notch/Delta4 signaling inhibits human megakaryocytic terminal differentiation.Q42911718
Prolonged continuous in vitro human platelet production using three-dimensional scaffoldsQ43136245
Fabrication of porous polysaccharide-based scaffolds using a combined freeze-drying/cross-linking processQ43136909
Biomimetic macroporous PEG hydrogels as 3D scaffolds for the multiplication of human hematopoietic stem and progenitor cells.Q44899994
Human endothelial progenitor cell attachment to polysaccharide-based hydrogels: a pre-requisite for vascular tissue engineering.Q51061158
Interrelation between polyploidization and megakaryocyte differentiation: a gene profiling approach.Q51999245
Fucoidan in a 3D scaffold interacts with vascular endothelial growth factor and promotes neovascularization in mice.Q53288329
Summary of workshop findings for porcine myelomonocytic markersQ56775518
Cord blood-hematopoietic stem cell expansion in 3D fibrin scaffolds with stromal supportQ56999672
Magnetic micro-manipulations to probe the local physical properties of porous scaffolds and to confine stem cellsQ57559377
Proplatelet formation is regulated by the Rho/ROCK pathwayQ58125582
Porous Polysaccharide-Based Scaffolds for Human Endothelial Progenitor CellsQ58223845
Dynamic Visualization of Thrombopoiesis Within Bone MarrowQ58450371
Numerous growth factors, cytokines, and chemokines are secreted by human CD34+ cells, myeloblasts, erythroblasts, and megakaryoblasts and regulate normal hematopoiesis in an autocrine/paracrine mannerQ61942737
Protease-activating Receptor-4 Induces Full Platelet Spreading on a Fibrinogen MatrixQ62665022
Influence of polysaccharide composition on the biocompatibility of pullulan/dextran-based hydrogelsQ63944658
Changes in the platelet membrane glycoprotein IIb.IIIa complex during platelet activationQ68940569
Exposure of human megakaryocytes to high shear rates accelerates platelet productionQ84068352
Comparison of Two Platelet Activation Markers Using Flow Cytometry After In Vitro Shear Stress Exposure of Whole Human BloodQ85194020
Two differential flows in a bioreactor promoted platelet generation from human pluripotent stem cell-derived megakaryocytesQ86657049
Rho kinase inhibition drives megakaryocyte polyploidization and proplatelet formation through MYC and NFE2 downregulationQ87023629
Expansion of human hematopoietic stem/progenitor cells on decellularized matrix scaffoldsQ87259613
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectstem cell differentiationQ14864672
P304page(s)e0136652
P577publication date2015-01-01
P1433published inPLOS OneQ564954
P1476titleThree-Dimensional Environment Sustains Hematopoietic Stem Cell Differentiation into Platelet-Producing Megakaryocytes
P478volume10

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cites work (P2860)
Q92546005A comparison of haematopoietic stem cells from umbilical cord blood and peripheral blood for platelet production in a microfluidic device
Q52562901Alginate foam-based three-dimensional culture to investigate drug sensitivity in primary leukaemia cells.
Q38615234Calf Spleen Extractive Injection protects mice against cyclophosphamide-induced hematopoietic injury through G-CSF-mediated JAK2/STAT3 signaling
Q63944601Effect of cross-linking on the physicochemical and in vitro properties of pullulan/dextran microbeads
Q30819316LIM kinase/cofilin dysregulation promotes macrothrombocytopenia in severe von Willebrand disease-type 2B.
Q38663744Microfluidic on-chip biomimicry for 3D cell culture: a fit-for-purpose investigation from the end user standpoint
Q38784723Recent developments in ex vivo platelet production.

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