| review article | Q7318358 |
| scholarly article | Q13442814 |
| P2093 | author name string | Jo-Anna Reems | |
| Sijie Sun | |||
| Nicolas Pineault | |||
| P2860 | cites work | Evidence for a role of ADAM17 (TACE) in the regulation of platelet glycoprotein V | Q24293698 |
| Induced pluripotent stem cell lines derived from human somatic cells | Q27860597 | ||
| Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors | Q27860937 | ||
| Metalloproteinase regulation improves in vitro generation of efficacious platelets from mouse embryonic stem cells | Q30483213 | ||
| Cord blood is better than bone marrow for generating megakaryocytic progenitor cells | Q33327951 | ||
| Comparative analyses of megakaryocytes derived from cord blood and bone marrow | Q33332055 | ||
| Differences in megakaryocyte expansion potential between CD34(+) stem cells derived from cord blood, peripheral blood, and bone marrow from adults and children | Q33334328 | ||
| Oxygen tension influences the differentiation, maturation and apoptosis of human megakaryocytes | Q33335462 | ||
| Platelet-derived growth factor enhances ex vivo expansion of megakaryocytic progenitors from human cord blood | Q33337997 | ||
| Metalloproteinase inhibitors improve the recovery and hemostatic function of in vitro-aged or -injured mouse platelets | Q33349386 | ||
| Chemokine-mediated interaction of hematopoietic progenitors with the bone marrow vascular niche is required for thrombopoiesis | Q33358404 | ||
| Ex vivo expansion of megakaryocyte progenitor cells: cord blood versus mobilized peripheral blood | Q33368261 | ||
| An effective and simple expansion system for megakaryocyte progenitor cells using a combination of heparin with thrombopoietin and interleukin-11. | Q33369505 | ||
| Delivering new insight into the biology of megakaryopoiesis and thrombopoiesis | Q33376985 | ||
| AKR-501 (YM477) in combination with thrombopoietin enhances human megakaryocytopoiesis | Q33380317 | ||
| Thrombopoietin: the primary regulator of platelet production | Q33488715 | ||
| Thrombocytopenia in c-mpl-deficient mice | Q33491977 | ||
| Deficiencies in progenitor cells of multiple hematopoietic lineages and defective megakaryocytopoiesis in mice lacking the thrombopoietic receptor c-Mpl | Q33495712 | ||
| Thrombopoietin-stimulated ex vivo expansion of human bone marrow megakaryocytes | Q33498175 | ||
| Megakaryocytic progenitors can be generated ex vivo and safely administered to autologous peripheral blood progenitor cell transplant recipients. | Q33498988 | ||
| Thrombopoietin and hematopoietic stem cell development | Q33661916 | ||
| Role of thrombopoietin in hematopoietic stem cell and progenitor regulation | Q33901579 | ||
| Megakaryocytes and beyond: the birth of platelets | Q34215516 | ||
| Platelets generated in vitro from proplatelet-displaying human megakaryocytes are functional | Q34293080 | ||
| In vitro expansion of human megakaryocytes as a tool for studying megakaryocytic development and function | Q34416095 | ||
| Thrombopoietin, the Mp1 ligand, is essential for full megakaryocyte development | Q34425414 | ||
| Endomitosis of human megakaryocytes are due to abortive mitosis. | Q34466754 | ||
| Inhibition of human megakaryocytopoiesis in vitro by platelet factor 4 (PF4) and a synthetic COOH-terminal PF4 peptide | Q34571875 | ||
| Platelets in atherothrombosis | Q34986345 | ||
| In vivo platelet production from mature megakaryocytes: does platelet release occur via proplatelets? | Q36090943 | ||
| Compartmentalized megakaryocyte death generates functional platelets committed to caspase-independent death | Q36324970 | ||
| Gene expression profile of primary human CD34+CD38lo cells differentiating along the megakaryocyte lineage | Q38521780 | ||
| Ex vivo large-scale generation of human platelets from cord blood CD34+ cells | Q40290226 | ||
| Megakaryocytes derived from human embryonic stem cells: a genetically tractable system to study megakaryocytopoiesis and integrin function. | Q40328019 | ||
| A novel strategy for generating platelet-like fragments from megakaryocytic cell lines and human progenitor cells | Q40415814 | ||
| Induction of polyploidization in leukemic cell lines and primary bone marrow by Src kinase inhibitor SU6656. | Q40464481 | ||
| Generation of functional culture-derived platelets from CD34+ progenitor cells to study transgenes in the platelet environment | Q40490925 | ||
| Increased megakaryopoiesis in cultures of CD34-enriched cord blood cells maintained at 39 degrees C. | Q40521527 | ||
| Thrombocytopoiesis--analysis by membrane tracer and freeze-fracture studies on fresh human and cultured mouse megakaryocytes | Q41459667 | ||
| Cloning and expression of murine thrombopoietin cDNA and stimulation of platelet production in vivo | Q41460916 | ||
| Platelet production in the pulmonary capillary bed: new ultrastructural evidence for an old concept | Q41924284 | ||
| Prolonged continuous in vitro human platelet production using three-dimensional scaffolds | Q43136245 | ||
| Oxygen tension modulates the expression of cytokine receptors, transcription factors, and lineage-specific markers in cultured human megakaryocytes | Q43662438 | ||
| Platelet formation is the consequence of caspase activation within megakaryocytes | Q44083637 | ||
| Role of human interleukin-9 as a megakaryocyte potentiator in culture | Q44249425 | ||
| Ex vivo expansion of megakaryocyte precursors from umbilical cord blood CD34 cells in a closed liquid culture system | Q44372682 | ||
| Preferential ex vivo expansion of megakaryocytes from human cord blood CD34+-enriched cells in the presence of thrombopoietin and limiting amounts of stem cell factor and Flt-3 ligand | Q44476552 | ||
| AMG531 stimulates megakaryopoiesis in vitro by binding to Mpl. | Q44704490 | ||
| Tumor necrosis factor-alpha-converting enzyme (ADAM17) mediates GPIbalpha shedding from platelets in vitro and in vivo | Q45042577 | ||
| In vitro biological characteristics of human cord blood-derived megakaryocytes | Q45143190 | ||
| Flt3/Flk-2 ligand in combination with thrombopoietin decreases apoptosis in megakaryocyte development | Q47372876 | ||
| Ex vivo expansion of cord blood progenitors | Q47686617 | ||
| Oxygen tension alters the effects of cytokines on the megakaryocyte, erythrocyte, and granulocyte lineages | Q47726676 | ||
| Efficient in vitro megakaryocyte maturation using cytokine cocktails optimized by statistical experimental design. | Q50955292 | ||
| In vitro and in vivo megakaryocyte differentiation of fresh and ex-vivo expanded cord blood cells: rapid and transient megakaryocyte reconstitution. | Q51026832 | ||
| Enhanced expansion and maturation of megakaryocytic progenitors by fibronectin. | Q51040356 | ||
| Isolation of large numbers of enriched human megakaryocytes from liquid cultures of normal peripheral blood progenitor cells. | Q52469327 | ||
| Megakaryocyte endomitosis is a failure of late cytokinesis related to defects in the contractile ring and Rho/Rock signaling. | Q53461749 | ||
| Functional characterization of hNUDC as a novel accumulator that specifically acts on in vitro megakaryocytopoiesis and in vivo platelet production. | Q53638940 | ||
| Dynamic Visualization of Thrombopoiesis Within Bone Marrow | Q58450371 | ||
| The transmural passage of blood cells into myeloid sinusoids and the entry of platelets into the sinusoidal circulation; a scanning electron microscopic investigation | Q67441784 | ||
| Clonal growth of human megakaryocyte progenitors in serum-free cultures: effect of recombinant human interleukin 3 | Q68098017 | ||
| Effects of recombinant interferons on human megakaryocyte growth | Q68354426 | ||
| Human serum megakaryocyte colony-stimulating activity appears to be distinct from interleukin-3, granulocyte-macrophage colony-stimulating factor, and lymphocyte-conditioned medium | Q68525745 | ||
| Effect of interleukin 6 on in vitro human megakaryocytopoiesis: its interaction with other cytokines | Q69549710 | ||
| Aspects of platelet formation and release | Q70815622 | ||
| Expression of adhesion molecules on cytoplasmic processes of human megakaryocytes | Q71090205 | ||
| The effect of thrombopoietin on the proliferation and differentiation of murine hematopoietic stem cells | Q71128007 | ||
| Thrombopoietin supports proliferation of human primitive hematopoietic cells in synergy with steel factor and/or interleukin-3 | Q71228731 | ||
| Recombinant human megakaryocyte growth and development factor (rHuMGDF), a ligand for c-Mpl, produces functional human platelets in vitro | Q71701689 | ||
| The Mpl-ligand or thrombopoietin or megakaryocyte growth and differentiative factor has both direct proliferative and differentiative activities on human megakaryocyte progenitors | Q71709655 | ||
| Unilineage megakaryocytic proliferation and differentiation of purified hematopoietic progenitors in serum-free liquid culture | Q71789377 | ||
| Human bone marrow microvascular endothelial cells support long-term proliferation and differentiation of myeloid and megakaryocytic progenitors | Q71789644 | ||
| Circulating megakaryocytes and platelet release in the lung | Q72592711 | ||
| The development of human megakaryocytes: III. Development of mature megakaryocytes from highly purified committed progenitors in synthetic culture media and inhibition of thrombopoietin-induced polyploidization by interleukin-3 | Q72996024 | ||
| Ultrastructure of platelet formation by human megakaryocytes cultured with the Mpl ligand | Q73260630 | ||
| The platelet storage lesion | Q73317263 | ||
| Production of functional platelets by differentiated embryonic stem (ES) cells in vitro | Q73812286 | ||
| Glycoprotein VI is a major collagen receptor for platelet activation: it recognizes the platelet-activating quaternary structure of collagen, whereas CD36, glycoprotein IIb/IIIa, and von Willebrand factor do not | Q74033676 | ||
| Effects of cytokines on platelet production from blood and marrow CD34+ cells | Q74106130 | ||
| Stromal-conditioned medium synergizes with thrombopoietin in stimulating megakaryocytopoiesis | Q74218435 | ||
| Higher pH promotes megakaryocytic maturation and apoptosis | Q74444970 | ||
| Cord blood megakaryocytes do not complete maturation, as indicated by impaired establishment of endomitosis and low expression of G1/S cyclins upon thrombopoietin-induced differentiation | Q74445827 | ||
| Adhesion receptors as regulators of the hematopoietic process | Q77380970 | ||
| Different ploidy levels of megakaryocytes generated from peripheral or cord blood CD34+ cells are correlated with different levels of platelet release | Q77535996 | ||
| Generation of functional platelets from human embryonic stem cells in vitro via ES-sacs, VEGF-promoted structures that concentrate hematopoietic progenitors | Q81015137 | ||
| Characterization of the effects and potential mechanisms leading to increased megakaryocytic differentiation under mild hyperthermia | Q81392316 | ||
| Exposure of human megakaryocytes to high shear rates accelerates platelet production | Q84068352 | ||
| P433 | issue | 1 | |
| P304 | page(s) | 33-43 | |
| P577 | publication date | 2010-01-01 | |
| P1433 | published in | Transfusion Medicine Reviews | Q15758511 |
| P1476 | title | In vitro megakaryocyte production and platelet biogenesis: state of the art | |
| P478 | volume | 24 |
| Q88907819 | A Fully Automated High-Throughput Flow Cytometry Screening System Enabling Phenotypic Drug Discovery |
| Q38568042 | A journey to produce platelets in vitro |
| Q33426729 | A novel bioreactor and culture method drives high yields of platelets from stem cells |
| Q41107641 | Aryl hydrocarbon receptor-dependent enrichment of a megakaryocytic precursor with a high potential to produce proplatelets |
| Q38072649 | Blood stem cell products: toward sustainable benchmarks for clinical translation |
| Q42186159 | Bone marrow stromal cells transduced with a thrombopoietin, interleukin-6, and interleukin-11 syncretic gene induce cord mononuclear cells to generate platelets in vitro. |
| Q38109322 | Challenges in the management of the blood supply |
| Q33409225 | Designer cytokine hyper interleukin 11 (H11) is a megakaryopoietic factor |
| Q92219763 | Enabling Large-Scale Ex Vivo Production of Megakaryocytes from CD34+ Cells Using Gas-Permeable Surfaces |
| Q88072705 | Enhancing functional platelet release in vivo from in vitro-grown megakaryocytes using small molecule inhibitors |
| Q38187494 | Ex vivo production of platelets from stem cells |
| Q30538380 | Expression of plasma membrane receptor genes during megakaryocyte development |
| Q47879370 | Human adipose tissue-derived stromal cells can differentiate into megakaryocytes and platelets by secreting endogenous thrombopoietin |
| Q89972393 | Human megakaryocytic microparticles induce de novo platelet biogenesis in a wild-type murine model |
| Q36358673 | Identifying and enriching platelet-producing human stem cell-derived megakaryocytes using factor V uptake. |
| Q90489529 | In vitro culture of murine megakaryocytes from fetal liver-derived hematopoietic stem cells |
| Q97533489 | In vitro platelet production for transfusion purposes: Where are we now? |
| Q36370865 | Induction of functional platelets from mouse and human fibroblasts by p45NF-E2/Maf |
| Q33405752 | Infusion of megakaryocytic progenitor products generated from cord blood hematopoietic stem/progenitor cells: results of the phase 1 study |
| Q47196236 | Large-scale culture of a megakaryocytic progenitor cell line with a single-use bioreactor system |
| Q50455895 | Loss of the ability to generate large burst-forming unit-like megakaryocytic colonies from thawed cord blood in semisolid cultures after short term suspension culture. |
| Q49827384 | Megakaryocyte Differentiation and Platelet Formation from Human Cord Blood-derived CD34+ Cells. |
| Q64266287 | Megakaryocytes and platelets from a novel human adipose tissue-derived mesenchymal stem cell line |
| Q34613413 | OP9 bone marrow stroma cells differentiate into megakaryocytes and platelets |
| Q53734886 | Optimizing megakaryocyte polyploidization by targeting multiple pathways of cytokinesis. |
| Q26743455 | Platelet generation in vivo and in vitro |
| Q33789872 | Platelets generated from human embryonic stem cells are functional in vitro and in the microcirculation of living mice |
| Q37857709 | Potential clinical applications for human pluripotent stem cell-derived blood components |
| Q42210360 | Proliferation extent of CD34+ cells as a key parameter to maximize megakaryocytic differentiation of umbilical cord blood-derived hematopoietic stem/progenitor cells in a two-stage culture protocol |
| Q42915377 | Promoting Effects of Heparin on ex vivo Expansion of Megakaryocytopoiesis from Human Cord Blood CD34+ Cells |
| Q33409045 | ROS-mediated platelet generation: a microenvironment-dependent manner for megakaryocyte proliferation, differentiation, and maturation |
| Q34671302 | Road blocks in making platelets for transfusion |
| Q38197714 | Safety of platelet transfusion: past, present and future. |
| Q43010381 | Scalable generation of universal platelets from human induced pluripotent stem cells. |
| Q46499258 | The genomic and proteomic blueprint of mouse megakaryocytes derived from embryonic stem cells. |
| Q27321267 | Three-Dimensional Environment Sustains Hematopoietic Stem Cell Differentiation into Platelet-Producing Megakaryocytes |
| Q35579676 | Three-dimensional system for the in vitro study of megakaryocytes and functional platelet production using silk-based vascular tubes |
| Q26770860 | Understanding platelet generation from megakaryocytes: implications for in vitro-derived platelets |
| Q95313624 | miRNA-98-5p Targeting IGF2BP1 Induces Mesenchymal Stem Cell Apoptosis by Modulating PI3K/Akt and p53 in Immune Thrombocytopenia |
| Q44209682 | miRNAs can increase the efficiency of ex vivo platelet generation |
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