| scholarly article | Q13442814 |
| P50 | author | Guido Kroemer | Q19508945 |
| William Vainchenker | Q3569009 | ||
| Olivier Hermine | Q28322530 | ||
| Eric Daugas | Q42889813 | ||
| Stéphane de Botton | Q57031523 | ||
| P2093 | author name string | Najet Debili | |
| Yael Zermati | |||
| Siham Sabri | |||
| Jacques Emmanuel Guidotti | |||
| P433 | issue | 4 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 1310-1317 | |
| P577 | publication date | 2002-08-01 | |
| P1433 | published in | Blood | Q885070 |
| P1476 | title | Platelet formation is the consequence of caspase activation within megakaryocytes | |
| P478 | volume | 100 |
| Q33380951 | 15-deoxy-delta12,14-PGJ2 enhances platelet production from megakaryocytes |
| Q40073655 | A gain-of-function mutation in TNFRSF13B is a candidate for predisposition to familial or sporadic immune thrombocytopenia |
| Q33402025 | A megakaryocyte with no platelets: anti-platelet antibodies, apoptosis, and platelet production |
| Q21144930 | A meta-analysis and genome-wide association study of platelet count and mean platelet volume in african americans |
| Q33382084 | A murine model for human immune thrombocytopenic purpura and comparative analysis of multiple gene expression in bone marrow and spleen |
| Q33378983 | A mutation of human cytochrome c enhances the intrinsic apoptotic pathway but causes only thrombocytopenia. |
| Q46108318 | A non-apoptotic role for Fas/FasL in erythropoiesis |
| Q50091910 | A novel mode of stimulating platelet formation activity in megakaryocytes with peanut skin extract |
| Q30478057 | A novel role for microtubules in apoptotic chromatin dynamics and cellular fragmentation |
| Q37270690 | A novel variant on chromosome 7q22.3 associated with mean platelet volume, counts, and function |
| Q33303491 | A systems-biology analysis of isogenic megakaryocytic and granulocytic cultures identifies new molecular components of megakaryocytic apoptosis |
| Q33299579 | A ubiquitin ligase complex regulates caspase activation during sperm differentiation in Drosophila |
| Q48141066 | Acetylated Signal Transducer and Activator of Transcription 3 Functions as Molecular Adaptor Independent of Transcriptional Activity During Human Cardiogenesis. |
| Q35416666 | Actin inhibition increases megakaryocyte proplatelet formation through an apoptosis-dependent mechanism |
| Q53541279 | Acute and chronic microvascular alterations in a mouse model of ischemic acute kidney injury. |
| Q27016041 | Apoptosis: role in myeloid cell development |
| Q35811887 | Apoptotic mechanisms in the control of erythropoiesis |
| Q38735628 | Bcl-2 proteins in development, health, and disease of the hematopoietic system. |
| Q91813300 | Bone marrow endothelial cell-derived interleukin-4 contributes to thrombocytopenia in acute myeloid leukemia |
| Q33377273 | CD8+ T cells suppress autologous megakaryocyte apoptosis in idiopathic thrombocytopenic purpura |
| Q88492427 | CDPs: caspase-dependent non-lethal cellular processes |
| Q64376239 | Caspase Cleavage of Gelsolin Is an Inductive Cue for Pathologic Cardiac Hypertrophy |
| Q33383251 | Caspase activation is involved in early megakaryocyte differentiation but not in platelet production from megakaryocytes |
| Q57082822 | Caspase activation is not death |
| Q36807303 | Caspase activity mediates the differentiation of embryonic stem cells. |
| Q24595616 | Caspase-2: killer, savior and safeguard--emerging versatile roles for an ill-defined caspase |
| Q41818131 | Caspase-activated ROCK-1 allows erythroblast terminal maturation independently of cytokine-induced Rho signaling. |
| Q36430147 | Caspases at the crossroads of immune-cell life and death |
| Q34652977 | Caspases in cell survival, proliferation and differentiation. |
| Q35972102 | Cell death signaling and anticancer therapy |
| Q28505080 | Characterization of the megakaryocyte demarcation membrane system and its role in thrombopoiesis |
| Q36324970 | Compartmentalized megakaryocyte death generates functional platelets committed to caspase-independent death |
| Q33391076 | Contributions of TRAIL-mediated megakaryocyte apoptosis to impaired megakaryocyte and platelet production in immune thrombocytopenia |
| Q33393835 | Covalently immobilized glycosaminoglycans enhance megakaryocyte progenitor expansion and platelet release |
| Q52901915 | Current models of thrombopoiesis |
| Q99418701 | De novo lipogenesis is essential for platelet production in humans |
| Q39052443 | Differential regulation of the apoptotic machinery during megakaryocyte differentiation and platelet production by inhibitor of apoptosis protein Livin |
| Q30493467 | Diffusion is capable of translating anisotropic apoptosis initiation into a homogeneous execution of cell death |
| Q46265048 | Dopamine induces platelet production from megakaryocytes via oxidative stress-mediated signaling pathways |
| Q38023263 | Driving apoptosis-relevant proteins toward neural differentiation |
| Q39490831 | Drosophila caspase transduces Shaggy/GSK-3beta kinase activity in neural precursor development |
| Q42227148 | Dysregulation of the intrinsic apoptotic pathway mediates megakaryocytic hyperplasia in myeloproliferative neoplasms. |
| Q35013020 | Effector caspases and leukemia |
| Q40408299 | Enforced expression of KDR receptor promotes proliferation, survival and megakaryocytic differentiation of TF1 progenitor cell line. |
| Q38187494 | Ex vivo production of platelets from stem cells |
| Q47243841 | Exposure of pregnant sows to deoxynivalenol during 35-70 days of gestation does not affect pathomorphological and immunohistochemical properties of fetal organs |
| Q34219541 | Gender dependence for a subset of the low-abundance signaling proteome in human platelets |
| Q44907948 | HSP70, an erythropoiesis regulator that determines the fate of erythroblasts between death and differentiation |
| Q54642108 | Heat-shock protein 60 translocates to the surface of apoptotic cells and differentiated megakaryocytes and stimulates phagocytosis. |
| Q34346864 | Hematopoietic stem cell responsiveness to exogenous signals is limited by caspase-3. |
| Q33362092 | Hemodialysis, erythropoietin and megakaryocytopoiesis: factors in uremic thrombocytopathy and thrombophilia |
| Q33378422 | Historical review: megakaryopoiesis and thrombopoiesis |
| Q88921642 | How to Avoid False-Negative and False-Positive Diagnoses of Platelet Apoptosis: Illustrative Experimental and Clinically Relevant Cases |
| Q28263707 | Human platelet Ca2+-ATPases: new markers of cell differentiation as illustrated in idiopathic scoliosis |
| Q27310713 | IL-1α induces thrombopoiesis through megakaryocyte rupture in response to acute platelet needs |
| Q36358673 | Identifying and enriching platelet-producing human stem cell-derived megakaryocytes using factor V uptake. |
| Q37644828 | In vitro megakaryocyte production and platelet biogenesis: state of the art |
| Q36090943 | In vivo platelet production from mature megakaryocytes: does platelet release occur via proplatelets? |
| Q42142487 | Incomplete activation of macrophage apoptosis during intracellular replication of Legionella pneumophila. |
| Q38469114 | Increased immunoreactivities of cleaved αII-spectrin and cleaved caspase-3 in the aged dog spinal cord. |
| Q64103085 | Inhibition of Tropomyosin Receptor Kinase A Signaling Negatively Regulates Megakaryopoiesis and induces Thrombopoiesis |
| Q33413168 | Interpreting the developmental dance of the megakaryocyte: a review of the cellular and molecular processes mediating platelet formation |
| Q33423736 | Interspecies Variation in the Functional Consequences of Mutation of Cytochrome c |
| Q33421982 | Intrinsically impaired platelet production in some patients with persistent or chronic immune thrombocytopenia |
| Q33413048 | Lessons in platelet production from inherited thrombocytopenias |
| Q36680112 | M10, a caspase cleavage product of the hepatocyte growth factor receptor, interacts with Smad2 and demonstrates antifibrotic properties in vitro and in vivo |
| Q35091412 | Many cuts to ruin: a comprehensive update of caspase substrates |
| Q36468900 | Mechanisms of cytochrome c release from mitochondria |
| Q30479625 | Mechanisms of organelle transport and capture along proplatelets during platelet production |
| Q36230854 | Mechanisms of thrombopoiesis |
| Q36075300 | Megakaryocyte apoptosis: sorting out the signals |
| Q30485800 | Megakaryocyte-derived microparticles: direct visualization and distinction from platelet-derived microparticles |
| Q34215516 | Megakaryocytes and beyond: the birth of platelets |
| Q90282070 | Megakaryocytes contain extranuclear histones and may be a source of platelet-associated histones during sepsis |
| Q33397149 | Megakaryocytes possess a functional intrinsic apoptosis pathway that must be restrained to survive and produce platelets |
| Q33372724 | Megakaryocytic dysfunction in myelodysplastic syndromes and idiopathic thrombocytopenic purpura is in part due to different forms of cell death |
| Q36558011 | Mitochondria in hematopoiesis and hematological diseases. |
| Q47843948 | Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. |
| Q38667534 | More alive than dead: non-apoptotic roles for caspases in neuronal development, plasticity and disease. |
| Q24321712 | Mutation of the beta1-tubulin gene associated with congenital macrothrombocytopenia affecting microtubule assembly |
| Q29614484 | NIX is required for programmed mitochondrial clearance during reticulocyte maturation |
| Q27011322 | New roles for old enzymes: killer caspases as the engine of cell behavior changes |
| Q24319057 | No death without life: vital functions of apoptotic effectors |
| Q35874918 | Non-apoptotic functions of apoptosis-regulatory proteins |
| Q35557615 | Non-apoptotic functions of caspases in cellular proliferation and differentiation |
| Q39140591 | Non-apoptotic functions of caspases in myeloid cell differentiation. |
| Q47677127 | Osteogenic Potential of Caspases Related to Endochondral Ossification. |
| Q42271708 | Overexpression of nuclear distribution protein (hNUDC) causes pro-apoptosis and differentiation in Dami megakaryocytes |
| Q34251140 | PP2A:B56ϵ, a Substrate of Caspase-3, Regulates p53-dependent and p53-independent Apoptosis during Development |
| Q28941780 | Partial cleavage of RasGAP by caspases is required for cell survival in mild stress conditions |
| Q33407443 | Pathogenesis and management of inherited thrombocytopenias: rationale for the use of thrombopoietin-receptor agonists |
| Q35222080 | Physiological functions of caspases beyond cell death |
| Q27024841 | Piecing together the humoral and cellular mechanisms of immune thrombocytopenia |
| Q34040202 | Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) impairs the regulation of apoptosis in megakaryocytes by activating NF-κB: a proteomic study |
| Q35901696 | Pivotal contributions of megakaryocytes to the biology of idiopathic myelofibrosis |
| Q33398769 | Platelet apoptosis in paediatric immune thrombocytopenia is ameliorated by intravenous immunoglobulin |
| Q35119432 | Platelet apoptosis in stored platelet concentrates and other models |
| Q33413970 | Platelet production proceeds independently of the intrinsic and extrinsic apoptosis pathways |
| Q37196840 | Platelets: developmental biology, physiology, and translatable platforms for preclinical investigation and drug development. |
| Q34148521 | Post-translational myristoylation: Fat matters in cellular life and death |
| Q35878720 | Programmed cell death in animal development and disease |
| Q38764769 | Proplatelet formation in megakaryocytes is associated with endoplasmic reticulum stress |
| Q33938189 | Proplatelet formation of megakaryocytes is triggered by autocrine-synthesized estradiol |
| Q35048911 | Prostacyclin prevents nitric oxide-induced megakaryocyte apoptosis |
| Q90317147 | Pulmonary Infection Within 100 Days After Transplantation Impaired Platelet Recovery in Patients with Hematologic Malignancies: A Propensity-Score-Matched Analysis |
| Q33409045 | ROS-mediated platelet generation: a microenvironment-dependent manner for megakaryocyte proliferation, differentiation, and maturation |
| Q57220115 | Re-examining the role of cytochrome c in cell death |
| Q33424130 | Recruitment of CD8(+) T cells into bone marrow might explain the suppression of megakaryocyte apoptosis through high expression of CX3CR1(+) in prolonged isolated thrombocytopenia after allogeneic hematopoietic stem cell transplantation |
| Q43117706 | Regional differences in the temporal expression of non-apoptotic caspase-3-positive bergmann glial cells in the developing rat cerebellum |
| Q39305649 | Restoring TRAIL Induced Apoptosis Using Naturopathy. Hercules Joins Hand with Nature to Triumph Over Lernaean Hydra. |
| Q58720234 | Role of p53 and transcription-independent p53-induced apoptosis in shear-stimulated megakaryocytic maturation, particle generation, and platelet biogenesis |
| Q36173581 | STAT1 promotes megakaryopoiesis downstream of GATA-1 in mice |
| Q24320238 | SUMO conjugation to the matrix attachment region-binding protein, special AT-rich sequence-binding protein-1 (SATB1), targets SATB1 to promyelocytic nuclear bodies where it undergoes caspase cleavage |
| Q39035221 | Secretory lysosomes of mouse mast cells store and exocytose active caspase-3 in a strictly granzyme B dependent manner |
| Q42662112 | Separation of in-vitro-derived megakaryocytes and platelets using spinning-membrane filtration |
| Q34293014 | Shear enhances thrombopoiesis and formation of microparticles that induce megakaryocytic differentiation of stem cells. |
| Q38060189 | Signaling pathways in tumor vasculogenic mimicry |
| Q53625976 | Stat3 cleavage by caspases: impact on full-length Stat3 expression, fragment formation, and transcriptional activity. |
| Q26799282 | Stem cell autotomy and niche interaction in different systems |
| Q53595082 | Sustained JNK signaling by proteolytically processed HPK1 mediates IL-3 independent survival during monocytic differentiation. |
| Q39239250 | TRAIL promotes membrane blebbing, detachment and migration of cells displaying a dysfunctional intrinsic pathway of apoptosis |
| Q37098148 | Tango7 directs cellular remodeling by the Drosophila apoptosome |
| Q35669864 | Tetraspanin CD9 participates in dysmegakaryopoiesis and stromal interactions in primary myelofibrosis |
| Q33773413 | The Jekyll and Hyde functions of caspases |
| Q33369405 | The biogenesis of platelets from megakaryocyte proplatelets |
| Q35181652 | The birth of the platelet |
| Q37455021 | The ins and outs of phospholipid asymmetry in the plasma membrane: roles in health and disease |
| Q35683839 | The kinder side of killer proteases: caspase activation contributes to neuroprotection and CNS remodeling |
| Q36685876 | The mouse as a model for human biology: a resource guide for complex trait analysis |
| Q43120475 | The regulation of proplatelet production |
| Q33412943 | The role of apoptosis in megakaryocytes and platelets |
| Q38779334 | Thrombin Maybe Plays an Important Role in MK Differentiation into Platelets |
| Q50897596 | Timing and expression level of protein kinase C epsilon regulate the megakaryocytic differentiation of human CD34 cells. |
| Q40170860 | Tissue inhibitor of metalloproteinase-1 promotes hematopoietic differentiation via caspase-3 upstream the MEKK1/MEK6/p38alpha pathway. |
| Q27015841 | Transcription factors in late megakaryopoiesis and related platelet disorders |
| Q33346373 | Tributyltin (TBT) induces ultra-rapid caspase activation independent of apoptosome formation in human platelets |
| Q36701821 | Tumor suppressor protein p53 regulates megakaryocytic polyploidization and apoptosis |
| Q40386078 | Twist is substrate for caspase cleavage and proteasome-mediated degradation. |
| Q36218213 | Vital functions for lethal caspases |
| Q95313624 | miRNA-98-5p Targeting IGF2BP1 Induces Mesenchymal Stem Cell Apoptosis by Modulating PI3K/Akt and p53 in Immune Thrombocytopenia |
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