A systems-biology analysis of isogenic megakaryocytic and granulocytic cultures identifies new molecular components of megakaryocytic apoptosis

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A systems-biology analysis of isogenic megakaryocytic and granulocytic cultures identifies new molecular components of megakaryocytic apoptosis is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1007534121
P356DOI10.1186/1471-2164-8-384
P932PMC publication ID2204013
P698PubMed publication ID17953764
P5875ResearchGate publication ID5891497

P50authorWilliam M. MillerQ41433424
P2093author name stringChi Chen
Min Wang
Eleftherios T Papoutsakis
Carlos J Paredes
Li Ting Huang
Peter G Fuhrken
Pani Apostolidis
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The end is just the beginning: megakaryocyte apoptosis and platelet releaseQ33340621
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The I kappa B kinase (IKK) complex is tripartite and contains IKK gamma but not IKAP as a regular component.Q52970987
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Characterization of platelet-releasable forms of beta-amyloid precursor proteins: the effect of thrombinQ67919360
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P407language of work or nameEnglishQ1860
P921main subjectsystems biologyQ815297
P304page(s)384
P577publication date2007-10-22
P1433published inBMC GenomicsQ15765854
P1476titleA systems-biology analysis of isogenic megakaryocytic and granulocytic cultures identifies new molecular components of megakaryocytic apoptosis
P478volume8

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cites work (P2860)
Q33569847Distinct, strict requirements for Gfi-1b in adult bone marrow red cell and platelet generation
Q33413336Expandable megakaryocyte cell lines enable clinically applicable generation of platelets from human induced pluripotent stem cells
Q38514442Gene Ontology-driven transcriptional analysis of CD34+ cell-initiated megakaryocytic cultures identifies new transcriptional regulators of megakaryopoiesis
Q33402409MKL1 and MKL2 play redundant and crucial roles in megakaryocyte maturation and platelet formation
Q42008823Mechanistic studies on the effects of nicotinamide on megakaryocytic polyploidization and the roles of NAD+ levels and SIRT inhibition
Q36778744Megakaryocytic Maturation in Response to Shear Flow Is Mediated by the Activator Protein 1 (AP-1) Transcription Factor via Mitogen-activated Protein Kinase (MAPK) Mechanotransduction
Q33351510Multiway modeling and analysis in stem cell systems biology
Q34040202Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) impairs the regulation of apoptosis in megakaryocytes by activating NF-κB: a proteomic study
Q36185474Proposed megakaryocytic regulon of p53: the genes engaged to control cell cycle and apoptosis during megakaryocytic differentiation
Q40402310Role of tumor suppressor p53 in megakaryopoiesis and platelet function
Q34293014Shear enhances thrombopoiesis and formation of microparticles that induce megakaryocytic differentiation of stem cells.
Q24627968The aryl hydrocarbon receptor (AHR) transcription factor regulates megakaryocytic polyploidization
Q36701821Tumor suppressor protein p53 regulates megakaryocytic polyploidization and apoptosis

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