| scholarly article | Q13442814 |
| P2093 | author name string | Mortimer Poncz | |
| Deborah L French | |||
| Paul Gadue | |||
| Xiuli Sim | |||
| P2860 | cites work | Glycoprotein VI is the collagen receptor in platelets which underlies tyrosine phosphorylation of the Fc receptor gamma-chain | Q24308747 |
| Initiation of platelet adhesion by arrest onto fibrinogen or translocation on von Willebrand factor | Q24317407 | ||
| IL-1α induces thrombopoiesis through megakaryocyte rupture in response to acute platelet needs | Q27310713 | ||
| Development of the definitive hematopoietic hierarchy in the mouse | Q28279272 | ||
| An inhibitor of Bcl-2 family proteins induces regression of solid tumours | Q29547595 | ||
| The pathophysiology of mitochondrial cell death | Q29547893 | ||
| Differentiation of embryonic stem cells to clinically relevant populations: lessons from embryonic development | Q29617978 | ||
| Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases | Q29622846 | ||
| Vascular niche promotes hematopoietic multipotent progenitor formation from pluripotent stem cells | Q30410059 | ||
| The megakaryocyte lineage originates from hemangioblast precursors and is an integral component both of primitive and of definitive hematopoiesis | Q30478945 | ||
| Metalloproteinase regulation improves in vitro generation of efficacious platelets from mouse embryonic stem cells | Q30483213 | ||
| Infusion of mature megakaryocytes into mice yields functional platelets | Q30497158 | ||
| A novel role of sphingosine 1-phosphate receptor S1pr1 in mouse thrombopoiesis | Q30528487 | ||
| Inducible Gata1 suppression expands megakaryocyte-erythroid progenitors from embryonic stem cells | Q30657328 | ||
| Platelet c-mpl expression is dysregulated in patients with essential thrombocythaemia but this is not of diagnostic value | Q73079916 | ||
| Markedly reduced expression of platelet c-mpl receptor in essential thrombocythemia | Q73838791 | ||
| Different ploidy levels of megakaryocytes generated from peripheral or cord blood CD34+ cells are correlated with different levels of platelet release | Q77535996 | ||
| Markedly Reduced Expression of Platelet c-mpl Receptor in Essential Thrombocythemia | Q106483622 | ||
| Human definitive haemogenic endothelium and arterial vascular endothelium represent distinct lineages | Q30662761 | ||
| Metalloproteinase inhibitors improve the recovery and hemostatic function of in vitro-aged or -injured mouse platelets | Q33349386 | ||
| Chemokine-mediated interaction of hematopoietic progenitors with the bone marrow vascular niche is required for thrombopoiesis | Q33358404 | ||
| Megakaryocyte development and platelet production. | Q33372021 | ||
| Programmed anuclear cell death delimits platelet life span. | Q33374664 | ||
| TPO-independent megakaryocytopoiesis. | Q33377875 | ||
| Historical review: megakaryopoiesis and thrombopoiesis | Q33378422 | ||
| A mutation of human cytochrome c enhances the intrinsic apoptotic pathway but causes only thrombocytopenia. | Q33378983 | ||
| Platelet formation | Q33390619 | ||
| Navitoclax, a targeted high-affinity inhibitor of BCL-2, in lymphoid malignancies: a phase 1 dose-escalation study of safety, pharmacokinetics, pharmacodynamics, and antitumour activity | Q33392920 | ||
| Developmental differences in megakaryocytopoiesis are associated with up-regulated TPO signaling through mTOR and elevated GATA-1 levels in neonatal megakaryocytes | Q33394052 | ||
| Megakaryocytes possess a functional intrinsic apoptosis pathway that must be restrained to survive and produce platelets | Q33397149 | ||
| Mcl-1 and Bcl-xL regulate Bak/Bax-dependent apoptosis of the megakaryocytic lineage at multistages | Q33402322 | ||
| Infusion of megakaryocytic progenitor products generated from cord blood hematopoietic stem/progenitor cells: results of the phase 1 study | Q33405752 | ||
| Sphingosine kinase 2 (Sphk2) regulates platelet biogenesis by providing intracellular sphingosine 1-phosphate (S1P). | Q33408447 | ||
| The role of apoptosis in megakaryocytes and platelets | Q33412943 | ||
| Expandable megakaryocyte cell lines enable clinically applicable generation of platelets from human induced pluripotent stem cells | Q33413336 | ||
| Platelet production proceeds independently of the intrinsic and extrinsic apoptosis pathways | Q33413970 | ||
| SDF-1 dynamically mediates megakaryocyte niche occupancy and thrombopoiesis at steady state and following radiation injury | Q33414625 | ||
| Platelet demand modulates the type of intravascular protrusion of megakaryocytes in bone marrow | Q33416124 | ||
| The Ashwell-Morell receptor regulates hepatic thrombopoietin production via JAK2-STAT3 signaling | Q33419210 | ||
| Mouse prenatal platelet-forming lineages share a core transcriptional program but divergent dependence on MPL. | Q33422989 | ||
| Megakaryocytic progenitors can be generated ex vivo and safely administered to autologous peripheral blood progenitor cell transplant recipients. | Q33498988 | ||
| Platelet bioreactor-on-a-chip | Q34209300 | ||
| Platelets generated in vitro from proplatelet-displaying human megakaryocytes are functional | Q34293080 | ||
| T lymphocyte potential marks the emergence of definitive hematopoietic progenitors in human pluripotent stem cell differentiation cultures. | Q34316024 | ||
| Cytoskeletal mechanics of proplatelet maturation and platelet release. | Q34317068 | ||
| Programmable 3D silk bone marrow niche for platelet generation ex vivo and modeling of megakaryopoiesis pathologies. | Q35252648 | ||
| Actin inhibition increases megakaryocyte proplatelet formation through an apoptosis-dependent mechanism | Q35416666 | ||
| Neonatal platelet function. | Q35546807 | ||
| Comparative analysis of human ex vivo-generated platelets vs megakaryocyte-generated platelets in mice: a cautionary tale | Q35692415 | ||
| Desialylation accelerates platelet clearance after refrigeration and initiates GPIbα metalloproteinase-mediated cleavage in mice. | Q35750362 | ||
| Platelet function in term and preterm neonates | Q35796335 | ||
| Early block to erythromegakaryocytic development conferred by loss of transcription factor GATA-1. | Q35848534 | ||
| The specification of early hematopoiesis in the mammal. | Q36113928 | ||
| Embryonic development of the human hematopoietic system | Q36133384 | ||
| Full reconstitution of human platelets in humanized mice after macrophage depletion | Q36194261 | ||
| Transendothelial migration of megakaryocytes in response to stromal cell-derived factor 1 (SDF-1) enhances platelet formation | Q36401529 | ||
| Platelets in lung biology. | Q36897267 | ||
| Clonal genetic and hematopoietic heterogeneity among human-induced pluripotent stem cell lines. | Q37186456 | ||
| High-level transgene expression in induced pluripotent stem cell-derived megakaryocytes: correction of Glanzmann thrombasthenia | Q37535262 | ||
| A cut above the rest: targeted genome editing technologies in human pluripotent stem cells | Q37596293 | ||
| In vitro megakaryocyte production and platelet biogenesis: state of the art | Q37644828 | ||
| Mpl expression on megakaryocytes and platelets is dispensable for thrombopoiesis but essential to prevent myeloproliferation | Q37725327 | ||
| Hematopoiesis: a human perspective | Q37981372 | ||
| Challenges and promises for the development of donor-independent platelet transfusions | Q38074224 | ||
| Erythro-myeloid progenitors: "definitive" hematopoiesis in the conceptus prior to the emergence of hematopoietic stem cells | Q38149595 | ||
| Ex vivo production of platelets from stem cells | Q38187494 | ||
| Biomanufacture of human platelets for transfusion: Rationale and approaches | Q38199327 | ||
| Platelet transfusion: a systematic review of the clinical evidence | Q38267183 | ||
| A lineage of diploid platelet-forming cells precedes polyploid megakaryocyte formation in the mouse embryo | Q38305372 | ||
| Differentiation of pluripotent stem cells into endothelial cells | Q38376496 | ||
| A Doxycycline-Inducible System for Genetic Correction of iPSC Disease Models | Q38915585 | ||
| Utilization of the AAVS1 safe harbor locus for hematopoietic specific transgene expression and gene knockdown in human ES cells | Q39015278 | ||
| Biogenesis of the demarcation membrane system (DMS) in megakaryocytes | Q39327416 | ||
| Controlled shedding of platelet glycoprotein (GP)VI and GPIb-IX-V by ADAM family metalloproteinases. | Q40143775 | ||
| Platelet production in the pulmonary capillary bed: new ultrastructural evidence for an old concept | Q41924284 | ||
| Separation of in-vitro-derived megakaryocytes and platelets using spinning-membrane filtration | Q42662112 | ||
| Platelets mediate lymphovenous hemostasis to maintain blood-lymphatic separation throughout life. | Q42779021 | ||
| Scalable generation of universal platelets from human induced pluripotent stem cells. | Q43010381 | ||
| Closure times measured by the platelet function analyzer PFA-100 are longer in neonatal blood compared to cord blood samples | Q43249010 | ||
| Evidence for the presence of murine primitive megakaryocytopoiesis in the early yolk sac. | Q43551007 | ||
| Two distinct pathways regulate platelet phosphatidylserine exposure and procoagulant function. | Q46040273 | ||
| Mitochondrial control of platelet apoptosis: effect of cyclosporin A, an inhibitor of the mitochondrial permeability transition pore | Q46111834 | ||
| How I treat patients with massive hemorrhage | Q47803089 | ||
| Developmental changes in human megakaryopoiesis. | Q50738139 | ||
| GPVI down-regulation in murine platelets through metalloproteinase-dependent shedding. | Q50889027 | ||
| Mcl-1 and Bcl-xL are co-regulated by IL-6 in human myeloma cells. | Q52826978 | ||
| Differentially regulated GPVI ectodomain shedding by multiple platelet-expressed proteinases. | Q53311584 | ||
| Bcl-2 family proteins are essential for platelet survival. | Q53581386 | ||
| Platelet transfusions | Q56505470 | ||
| Mcl-1 and Bcl-xL coordinately regulate megakaryocyte survival | Q57681950 | ||
| Dynamic Visualization of Thrombopoiesis Within Bone Marrow | Q58450371 | ||
| Studies with a murine monoclonal antibody that abolishes ristocetin-induced binding of von Willebrand factor to platelets: additional evidence in support of GPIb as a platelet receptor for von Willebrand factor | Q70237272 | ||
| Platelet glycocalicin. Its membrane association and solubilization in aqueous media | Q71499599 | ||
| P433 | issue | 10 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | cell biology | Q7141 |
| P304 | page(s) | 1227-33 | |
| P577 | publication date | 2016-03-10 | |
| P1433 | published in | Blood | Q885070 |
| P1476 | title | Understanding platelet generation from megakaryocytes: implications for in vitro-derived platelets | |
| P478 | volume | 127 |
| Q92546005 | A comparison of haematopoietic stem cells from umbilical cord blood and peripheral blood for platelet production in a microfluidic device |
| Q47257067 | A uniform-shear rate microfluidic bioreactor for real-time study of proplatelet formation and rapidly-released platelets |
| Q90680103 | CD45 expression discriminates waves of embryonic megakaryocytes in the mouse |
| Q88366972 | Concise Review: Bipotent Megakaryocytic-Erythroid Progenitors: Concepts and Controversies |
| Q38877308 | Development of autologous blood cell therapies |
| Q41196414 | Dissecting the metabolic pathways controlling platelet survival in vivo: are our platelets what they eat? |
| Q46265048 | Dopamine induces platelet production from megakaryocytes via oxidative stress-mediated signaling pathways |
| Q88072705 | Enhancing functional platelet release in vivo from in vitro-grown megakaryocytes using small molecule inhibitors |
| Q33441252 | FLI1 level during megakaryopoiesis affects thrombopoiesis and platelet biology. |
| Q36358673 | Identifying and enriching platelet-producing human stem cell-derived megakaryocytes using factor V uptake. |
| Q51740307 | Intravenous administration of synthetic platelets (SynthoPlateTM) in a mouse liver injury model of uncontrolled hemorrhage improves hemostasis. |
| Q47550235 | MEIS1 Regulates Hemogenic Endothelial Generation, Megakaryopoiesis, and Thrombopoiesis in Human Pluripotent Stem Cells by Targeting TAL1 and FLI1. |
| Q40133462 | Mean Platelet Volume in Pemphigus Vulgaris. |
| Q30252483 | Neonatal expression of RNA-binding protein IGF2BP3 regulates the human fetal-adult megakaryocyte transition. |
| Q57167167 | On the Way to Platelet Production |
| Q57166306 | On the way to in vitro platelet production |
| Q28069839 | Pathophysiological Significance of Store-Operated Calcium Entry in Megakaryocyte Function: Opening New Paths for Understanding the Role of Calcium in Thrombopoiesis |
| Q90434536 | Platelet Biogenesis in the Lung Circulation |
| Q33443256 | Preparation of Platelet Concentrates for Research and Transfusion Purposes |
| Q39076420 | Progress in bio-manufacture of platelets for transfusion |
| Q57050184 | Screening for genes that regulate the differentiation of human megakaryocytic lineage cells |
| Q90692481 | The Blood Circulating Rare Cell Population. What is it and What is it Good For? |
| Q33442321 | The role of bone marrow microenvironment in platelet production and their implications for the treatment of thrombocytopenic diseases |
| Q38693576 | Threading an elephant through the eye of a needle: Where are platelets made? |
| Q90015665 | Tissue engineered models of healthy and malignant human bone marrow |
| Q33442786 | Towards the Manufacture of Megakaryocytes and Platelets for Clinical Application. |
| Q58784425 | Tyrosyl-tRNA synthetase stimulates thrombopoietin-independent hematopoiesis accelerating recovery from thrombocytopenia |
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