| scholarly article | Q13442814 |
| P2093 | author name string | Atsushi Kawaguchi | |
| Kyosuke Nagata | |||
| Eiji Obayashi | |||
| Jeremy R H Tame | |||
| Kanako Sugiyama | |||
| Sam-Yong Park | |||
| Yukari Suzuki | |||
| P2860 | cites work | Processing of X-ray diffraction data collected in oscillation mode | Q26778468 |
| Structural basis for the transition from initiation to elongation transcription in T7 RNA polymerase | Q27639673 | ||
| Structure and nuclear import function of the C-terminal domain of influenza virus polymerase PB2 subunit | Q27643860 | ||
| The structural basis for cap binding by influenza virus polymerase subunit PB2 | Q27650520 | ||
| Crystal structure of the polymerase PA(C)-PB1(N) complex from an avian influenza H5N1 virus | Q27651109 | ||
| The structural basis for an essential subunit interaction in influenza virus RNA polymerase | Q27651365 | ||
| Host Determinant Residue Lysine 627 Lies on the Surface of a Discrete, Folded Domain of Influenza Virus Polymerase PB2 Subunit | Q27651972 | ||
| Crystal structure of an avian influenza polymerase PA(N) reveals an endonuclease active site | Q27653656 | ||
| The cap-snatching endonuclease of influenza virus polymerase resides in the PA subunit | Q27653657 | ||
| Inference of macromolecular assemblies from crystalline state | Q27860457 | ||
| SOLVE and RESOLVE: automated structure solution and density modification | Q27860481 | ||
| Coot: model-building tools for molecular graphics | Q27860505 | ||
| Main-chain bond lengths and bond angles in protein structures | Q27860635 | ||
| Refinement of macromolecular structures by the maximum-likelihood method | Q27861011 | ||
| Automated MAD and MIR structure solution | Q27861114 | ||
| LIGPLOT: a program to generate schematic diagrams of protein-ligand interactions | Q27861128 | ||
| Influenza A virus RNA polymerase has the ability to stutter at the polyadenylation site of a viral RNA template during RNA replication | Q27863651 | ||
| Model suggesting that replication of influenza virus is regulated by stabilization of replicative intermediates | Q27863792 | ||
| A unique cap(m7GpppXm)-dependent influenza virion endonuclease cleaves capped RNAs to generate the primers that initiate viral RNA transcription | Q27865288 | ||
| Identification of two separate domains in the influenza virus PB1 protein involved in the interaction with the PB2 and PA subunits: a model for the viral RNA polymerase structure. | Q27867695 | ||
| RNA-dependent activation of primer RNA production by influenza virus polymerase: different regions of the same protein subunit constitute the two required RNA-binding sites | Q27867719 | ||
| Characterization of the 1918 influenza virus polymerase genes | Q28275749 | ||
| Differential activation of the influenza virus polymerase via template RNA binding | Q28646351 | ||
| Generation of influenza A viruses entirely from cloned cDNAs | Q29616768 | ||
| Avian influenza virus (H5N1): a threat to human health. | Q30361041 | ||
| The influenza virus nucleoprotein: a multifunctional RNA-binding protein pivotal to virus replication. | Q34119838 | ||
| Influenza virus polymerase basic protein 1 interacts with influenza virus polymerase basic protein 2 at multiple sites. | Q34395842 | ||
| Mutational analysis identifies functional domains in the influenza A virus PB2 polymerase subunit | Q35856754 | ||
| Evaluation of the genetic stability of the temperature-sensitive PB2 gene mutation of the influenza A/Ann Arbor/6/60 cold-adapted vaccine virus. | Q36637590 | ||
| Determination of influenza virus proteins required for genome replication | Q36793647 | ||
| Host factors for replication and transcription of the influenza virus genome. | Q37126318 | ||
| Direct evidence that the poly(A) tail of influenza A virus mRNA is synthesized by reiterative copying of a U track in the virion RNA template | Q39550180 | ||
| A single amino acid mutation in the PA subunit of the influenza virus RNA polymerase inhibits endonucleolytic cleavage of capped RNAs | Q39684553 | ||
| Monoclonal antibodies against influenza virus PB2 and NP polypeptides interfere with the initiation step of viral mRNA synthesis in vitro | Q40042184 | ||
| Evidence that the C-terminal PB2-binding region of the influenza A virus PB1 protein is a discrete alpha-helical domain | Q40060750 | ||
| Two of the three influenza viral polymerase proteins expressed by using baculovirus vectors form a complex in insect cells | Q40131402 | ||
| Fine mapping of the subunit binding sites of influenza virus RNA polymerase | Q40732397 | ||
| Molecular assembly of the influenza virus RNA polymerase: determination of the subunit-subunit contact sites | Q41171919 | ||
| Amino acid residues in the N-terminal region of the PA subunit of influenza A virus RNA polymerase play a critical role in protein stability, endonuclease activity, cap binding, and virion RNA promoter binding | Q43156905 | ||
| Functional domains of the influenza A virus PB2 protein: identification of NP- and PB1-binding sites | Q45662724 | ||
| Epitope mapping of cross-reactive monoclonal antibodies specific for the influenza A virus PA and PB2 polypeptides | Q45772602 | ||
| Complex formation between influenza virus polymerase proteins expressed in Xenopus oocytes | Q45843373 | ||
| P433 | issue | 12 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 1803-11 | |
| P577 | publication date | 2009-06-17 | |
| P1433 | published in | The EMBO Journal | Q1278554 |
| P1476 | title | Structural insight into the essential PB1–PB2 subunit contact of the influenza virus RNA polymerase | |
| P478 | volume | 28 |
| Q37239857 | 3D Molecular Modelling Study of the H7N9 RNA-Dependent RNA Polymerase as an Emerging Pharmacological Target |
| Q42149862 | A Broad Anti-influenza Hybrid Small Molecule That Potently Disrupts the Interaction of Polymerase Acidic Protein-Basic Protein 1 (PA-PB1) Subunits |
| Q45362440 | A novel function of the N-terminal domain of PA in assembly of influenza A virus RNA polymerase |
| Q34139013 | A novel functional site in the PB2 subunit of influenza A virus essential for acetyl-CoA interaction, RNA polymerase activity, and viral replication. |
| Q45353251 | A peptide derived from the C‐terminus of PB1 inhibits influenza virus replication by interfering with viral polymerase assembly |
| Q30429748 | Adaptation of Avian Influenza A Virus Polymerase in Mammals To Overcome the Host Species Barrier |
| Q38111647 | Adaptive mutations in the H5N1 polymerase complex |
| Q47553044 | Amino acid substitutions affecting aspartic acid 605 and valine 606 decrease the interaction strength between the influenza virus RNA polymerase PB2 '627' domain and the viral nucleoprotein |
| Q34261973 | Amino acid substitutions in PB1 of avian influenza viruses influence pathogenicity and transmissibility in chickens |
| Q38202012 | Antiviral strategies against influenza virus: towards new therapeutic approaches |
| Q38011755 | Antivirals Targeting Influenza A Virus |
| Q34055461 | Association of the influenza virus RNA polymerase subunit PB2 with the host chaperonin CCT. |
| Q38192283 | Bat-derived influenza-like viruses H17N10 and H18N11. |
| Q41919256 | Biochemical characterization of recombinant influenza A polymerase heterotrimer complex: Polymerase activity and mechanisms of action of nucleotide analogs |
| Q30426032 | Characterization in vitro and in vivo of a pandemic H1N1 influenza virus from a fatal case. |
| Q33834096 | CoESPRIT: a library-based construct screening method for identification and expression of soluble protein complexes |
| Q28084005 | Compounds with anti-influenza activity: present and future of strategies for the optimal treatment and management of influenza. Part II: Future compounds against influenza virus |
| Q27680799 | Conformational polymorphism of m7GTP in crystal structure of the PB2 middle domain from human influenza A virus |
| Q30360137 | Conserved features of the PB2 627 domain impact influenza virus polymerase function and replication |
| Q39730929 | Correlation between polymerase activity and pathogenicity in two duck H5N1 influenza viruses suggests that the polymerase contributes to pathogenicity |
| Q36711056 | Crystallization and X-ray crystallographic analysis of the cap-binding domain of influenza A virus H1N1 polymerase subunit PB2 |
| Q34189305 | Detecting Remote Sequence Homology in Disordered Proteins: Discovery of Conserved Motifs in the N-Termini of Mononegavirales phosphoproteins |
| Q34624418 | Disruption of the viral polymerase complex assembly as a novel approach to attenuate influenza A virus |
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| Q24567974 | Enzymology of RNA cap synthesis |
| Q38061423 | Evasion of influenza A viruses from innate and adaptive immune responses. |
| Q27319771 | Evidence for a Novel Mechanism of Influenza Virus-Induced Type I Interferon Expression by a Defective RNA-Encoded Protein |
| Q36409349 | Evolutionary conservation of influenza A PB2 sequences reveals potential target sites for small molecule inhibitors |
| Q40075092 | Genetic and codon usage bias analyses of polymerase genes of equine influenza virus and its relation to evolution. |
| Q40060300 | Genetic variation and co-evolutionary relationship of RNA polymerase complex segments in influenza A viruses |
| Q36523913 | Glycine at Position 622 in PB1 Contributes to the Virulence of H5N1 Avian Influenza Virus in Mice |
| Q34303782 | HMGB1 protein binds to influenza virus nucleoprotein and promotes viral replication |
| Q33799724 | Hantavirus nucleocapsid protein has distinct m7G cap- and RNA-binding sites |
| Q36433861 | Identification of a Novel Viral Protein Expressed from the PB2 Segment of Influenza A Virus |
| Q28476315 | Identification of a PA-binding peptide with inhibitory activity against influenza A and B virus replication |
| Q36191196 | Identification of a novel small-molecule compound targeting the influenza A virus polymerase PB1-PB2 interface. |
| Q28743238 | Identification of high-affinity PB1-derived peptides with enhanced affinity to the PA protein of influenza A virus polymerase |
| Q45363861 | Identification of influenza virus inhibitors which disrupt of viral polymerase protein-protein interactions |
| Q92638354 | Identifying genetic determinants of complex phenotypes from whole genome sequence data |
| Q89578518 | Impaired Nuclear Export of the Ribonucleoprotein Complex and Virus-Induced Cytotoxicity Combine to Restrict Propagation of the A/Duck/Malaysia/02/2001 (H9N2) Virus in Human Airway Cells |
| Q38325400 | Influence of PB2 host-range determinants on the intranuclear mobility of the influenza A virus polymerase |
| Q39224928 | Influenza A polymerase subunit PB2 possesses overlapping binding sites for polymerase subunit PB1 and human MAVS proteins. |
| Q34121115 | Influenza A virus polymerase: structural insights into replication and host adaptation mechanisms |
| Q36286466 | Influenza A virus preferentially snatches noncoding RNA caps |
| Q33953132 | Influenza A virus-generated small RNAs regulate the switch from transcription to replication |
| Q30791826 | Influenza virus RNA polymerase: insights into the mechanisms of viral RNA synthesis |
| Q38444279 | Influenza virus polymerase: Functions on host range, inhibition of cellular response to infection and pathogenicity. |
| Q33646273 | Innate immune evasion strategies of influenza viruses |
| Q34574076 | Integrating computational modeling and functional assays to decipher the structure-function relationship of influenza virus PB1 protein |
| Q34695795 | Interaction of the influenza A virus polymerase PB2 C-terminal region with importin alpha isoforms provides insights into host adaptation and polymerase assembly. |
| Q30421691 | Interferon-Inducible Protein Mx1 Inhibits Influenza Virus by Interfering with Functional Viral Ribonucleoprotein Complex Assembly |
| Q38384758 | Learning from structure-based drug design and new antivirals targeting the ribonucleoprotein complex for the treatment of influenza |
| Q39719150 | Limited compatibility of polymerase subunit interactions in influenza A and B viruses |
| Q36281749 | Molecular Determinants of Virulence and Stability of a Reporter-Expressing H5N1 Influenza A Virus |
| Q39398090 | Molecular interactions and trafficking of influenza A virus polymerase proteins analyzed by specific monoclonal antibodies. |
| Q38057050 | Mutations to A/Puerto Rico/8/34 PB1 gene improves seasonal reassortant influenza A virus growth kinetics |
| Q35011532 | New prospects for the rational design of antivirals |
| Q28080554 | New small-molecule drug design strategies for fighting resistant influenza A |
| Q30382441 | Nuclear import and assembly of influenza A virus RNA polymerase studied in live cells by fluorescence cross-correlation spectroscopy. |
| Q42221157 | Optimization of small-molecule inhibitors of influenza virus polymerase: from thiophene-3-carboxamide to polyamido scaffolds |
| Q39582914 | PB1-mediated virulence attenuation of H5N1 influenza virus in mice is associated with PB2 |
| Q35066744 | PB2 segment promotes high-pathogenicity of H5N1 avian influenza viruses in mice |
| Q30374833 | Phylogenetic Analysis and Functional Characterization of the Influenza A H5N1 PB2 Gene. |
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| Q30410407 | Polymerase activity of hybrid ribonucleoprotein complexes generated from reassortment between 2009 pandemic H1N1 and seasonal H3N2 influenza A viruses. |
| Q30234943 | Progress of small molecular inhibitors in the development of anti-influenza virus agents |
| Q38100767 | RNA synthetic mechanisms employed by diverse families of RNA viruses |
| Q30397586 | Rapid acquisition of polymorphic virulence markers during adaptation of highly pathogenic avian influenza H5N8 virus in the mouse |
| Q26863710 | Recent progress in structure-based anti-influenza drug design |
| Q38335070 | Recognition of Cap Structure by Influenza B Virus RNA Polymerase Is Less Dependent on the Methyl Residue than Recognition by Influenza A Virus Polymerase |
| Q35077609 | Replication-coupled and host factor-mediated encapsidation of the influenza virus genome by viral nucleoprotein. |
| Q40403931 | Screening for Novel Small-Molecule Inhibitors Targeting the Assembly of Influenza Virus Polymerase Complex by a Bimolecular Luminescence Complementation-Based Reporter System |
| Q27684927 | Structural analysis of H1N1 and H7N9 influenza A virus PA in the absence of PB1 |
| Q27671357 | Structural and Biochemical Basis for Development of Influenza Virus Inhibitors Targeting the PA Endonuclease |
| Q27676615 | Structural and Functional Characterization of K339T Substitution Identified in the PB2 Subunit Cap-binding Pocket of Influenza A Virus |
| Q34178189 | Structural and functional characterization of an influenza virus RNA polymerase-genomic RNA complex |
| Q40370553 | Structural characterization of recombinant IAV polymerase reveals a stable complex between viral PA-PB1 heterodimer and host RanBP5. |
| Q39099407 | Structural insights into RNA synthesis by the influenza virus transcription-replication machine |
| Q38090250 | Structure and assembly of the influenza A virus ribonucleoprotein complex |
| Q42181164 | Structure of influenza A polymerase bound to the viral RNA promoter |
| Q39580310 | Structure-based drug discovery for combating influenza virus by targeting the PA-PB1 interaction |
| Q30387969 | Structures of influenza A proteins and insights into antiviral drug targets. |
| Q30369689 | Survival analysis of infected mice reveals pathogenic variations in the genome of avian H1N1 viruses |
| Q39466061 | Targeting of the Influenza A Virus Polymerase PB1-PB2 Interface Indicates Strain-Specific Assembly Differences |
| Q28071809 | The Influenza Virus Polymerase Complex: An Update on Its Structure, Functions, and Significance for Antiviral Drug Design |
| Q27680700 | The N-Terminal Domain of PA from Bat-Derived Influenza-Like Virus H17N10 Has Endonuclease Activity |
| Q28542440 | The N-terminal fragment of a PB2 subunit from the influenza A virus (A/Hong Kong/156/1997 H5N1) effectively inhibits RNP activity and viral replication |
| Q42245125 | The N-terminal region of influenza virus polymerase PB1 adjacent to the PA binding site is involved in replication but not transcription of the viral genome |
| Q34055501 | The PB2 subunit of the influenza virus RNA polymerase affects virulence by interacting with the mitochondrial antiviral signaling protein and inhibiting expression of beta interferon |
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