System-level identification of transcriptional circuits underlying mammalian circadian clocks

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System-level identification of transcriptional circuits underlying mammalian circadian clocks is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1013980873
P356DOI10.1038/NG1504
P3181OpenCitations bibliographic resource ID3583226
P698PubMed publication ID15665827
P5875ResearchGate publication ID8065487

P50authorHiroki R UedaQ56997717
P2093author name stringWenbin Chen
Masamitsu Iino
Motoaki Sano
Yasufumi Shigeyoshi
Masayuki Machida
Seiichi Hashimoto
Satoko Hayashi
P2860cites workLethality and centrality in protein networksQ29547267
Error and attack tolerance of complex networksQ29547268
Network motifs: simple building blocks of complex networksQ29547340
Systems biology: a brief overviewQ29547514
Interacting molecular loops in the mammalian circadian clockQ29616206
mCRY1 and mCRY2 are essential components of the negative limb of the circadian clock feedback loopQ29616207
A functional genomics strategy reveals Rora as a component of the mammalian circadian clockQ29616297
A transcription factor response element for gene expression during circadian nightQ29617973
Nonredundant roles of the mPer1 and mPer2 genes in the mammalian circadian clockQ33949726
Three period homologs in mammals: differential light responses in the suprachiasmatic circadian clock and oscillating transcripts outside of brain.Q47877188
Dec1 and Dec2 are regulators of the mammalian molecular clockQ24313082
Coordination of circadian timing in mammalsQ27860673
NPAS2: an analog of clock operative in the mammalian forebrainQ27863700
Posttranslational Mechanisms Regulate the Mammalian Circadian ClockQ27863710
Circadian oscillation of a mammalian homologue of the Drosophila period geneQ27867702
Two period homologs: circadian expression and photic regulation in the suprachiasmatic nuclei.Q27867706
Role of the CLOCK protein in the mammalian circadian mechanismQ27867710
Positional syntenic cloning and functional characterization of the mammalian circadian mutation tau.Q28142534
The orphan nuclear receptor REV-ERBalpha controls circadian transcription within the positive limb of the mammalian circadian oscillatorQ28216502
Circadian rhythms from flies to humanQ28217953
Coordinated transcription of key pathways in the mouse by the circadian clockQ28217978
Positional cloning of the mouse circadian clock geneQ28238809
Antagonistic role of E4BP4 and PAR proteins in the circadian oscillatory mechanismQ28363498
Differential functions of mPer1, mPer2, and mPer3 in the SCN circadian clockQ28509438
The orphan receptor Rev-ErbA alpha activates transcription via a novel response elementQ28564147
Circadian Oscillation ofBMAL1,a Partner of a Mammalian Clock GeneClock,in Rat Suprachiasmatic NucleusQ28569989
Expression of the liver-enriched transcriptional activator protein DBP follows a stringent circadian rhythmQ28574009
Mammalian Cry1 and Cry2 are essential for maintenance of circadian rhythmsQ28584936
Mop3 is an essential component of the master circadian pacemaker in mammalsQ28591939
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectcircadian rhythmQ208353
P304page(s)187-92
P577publication date2005-02-01
P1433published inNature GeneticsQ976454
P1476titleSystem-level identification of transcriptional circuits underlying mammalian circadian clocks
P478volume37

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cites work (P2860)
Q33741010A class of circadian long non-coding RNAs mark enhancers modulating long-range circadian gene regulation.
Q21262990A direct repeat of E-box-like elements is required for cell-autonomous circadian rhythm of clock genes
Q39215656A disruption mechanism of the molecular clock in a MPTP mouse model of Parkinson's disease.
Q37902096A fluorescence spotlight on the clockwork development and metabolism of bone.
Q34017499A genome-scale resource for the functional characterization of Arabidopsis transcription factors.
Q24655808A genome-wide RNAi screen for modifiers of the circadian clock in human cells
Q34203771A mammalian circadian clock model incorporating daytime expression elements
Q39332067A master CLOCK hard at work brings rhythm to the transcriptome
Q36524975A mechanism for robust circadian timekeeping via stoichiometric balance
Q34988540A model of the cell-autonomous mammalian circadian clock
Q42118422A new symbolic representation for the identification of informative genes in replicated microarray experiments
Q28256459A non-canonical E-box within the MyoD core enhancer is necessary for circadian expression in skeletal muscle
Q35646834A novel E4BP4 element drives circadian expression of mPeriod2.
Q28588364A novel protein, CHRONO, functions as a core component of the mammalian circadian clock
Q64107911A period without PER: understanding 24-hour rhythms without classic transcription and translation feedback loops
Q90471300A photoperiodic time measurement served by the biphasic expression of Cryptochrome1ab in the zebrafish eye
Q35844303A promoter polymorphism in the Per3 gene is associated with alcohol and stress response.
Q64234933A saturated reaction in repressor synthesis creates a daytime dead zone in circadian clocks
Q34182250A survey of genomic studies supports association of circadian clock genes with bipolar disorder spectrum illnesses and lithium response
Q37600716A system biology approach to identify regulatory pathways underlying the neuroendocrine control of female puberty in rats and nonhuman primates
Q30482185A systematic survey in Arabidopsis thaliana of transcription factors that modulate circadian parameters
Q39300023A systems theoretic approach to analysis and control of mammalian circadian dynamics
Q35272964A time to remember: the role of circadian clocks in learning and memory.
Q24320084AUF1 contributes to Cryptochrome1 mRNA degradation and rhythmic translation
Q84874223Abnormal expressions of circadian-clock and circadian clock-controlled genes in the livers and kidneys of long-term, high-fat-diet-treated mice
Q36804423Accurate timekeeping is controlled by a cycling activator in Arabidopsis.
Q46231033Activation of TGF-beta/activin signalling resets the circadian clock through rapid induction of Dec1 transcripts
Q34454894Addiction and reward-related genes show altered expression in the postpartum nucleus accumbens
Q34072641Age-associated disruption of molecular clock expression in skeletal muscle of the spontaneously hypertensive rat.
Q37085998Aging in the circadian system: considerations for health, disease prevention and longevity
Q47134589Akt1 Controls the Timing and Amplitude of Vascular Circadian Gene Expression.
Q84611977Alterations of Circadian Clockworks During Differentiation and Apoptosis of Rat Ovarian Cells
Q41102947Alterations of Clock Gene RNA Expression in Brain Regions of a Triple Transgenic Model of Alzheimer's Disease.
Q48738662Alterations of the circadian system in Parkinson's disease patients.
Q89972752Altered circadian clock as a novel therapeutic target for constant darkness-induced insulin resistance and hyperandrogenism of polycystic ovary syndrome
Q58733894An incoherent feed-forward loop switches the Arabidopsis clock rapidly between two hysteretic states
Q34249512An intensity ratio of interlocking loops determines circadian period length.
Q36908152Analysis and synthesis of high-amplitude Cis-elements in the mammalian circadian clock
Q30540490Analysis of core circadian feedback loop in suprachiasmatic nucleus of mCry1-luc transgenic reporter mouse
Q21563498Analysis of gene regulatory networks in the mammalian circadian rhythm
Q39172767Analysis of the molecular pathophysiology of sleep disorders relevant to a disturbed biological clock
Q58558017Are 24-hour motor activity patterns associated with continued rapid response to ketamine?
Q35577052Assembly of a comprehensive regulatory network for the mammalian circadian clock: a bioinformatics approach
Q28508404BK calcium-activated potassium channels regulate circadian behavioral rhythms and pacemaker output
Q41848794Bayesian experts in exploring reaction kinetics of transcription circuits
Q42824517Beta-TrCP1-mediated degradation of PERIOD2 is essential for circadian dynamics
Q49989804Bmal1 knockdown suppresses wake and increases immobility without altering orexin A, corticotrophin-releasing hormone, or glutamate decarboxylase.
Q48384545CHRONO integrates behavioral stress and epigenetic control of metabolism
Q39545365CLOCK-controlled polyphonic regulation of circadian rhythms through canonical and noncanonical E-boxes
Q27333850Cardiomyocyte Circadian Oscillations Are Cell-Autonomous, Amplified by β-Adrenergic Signaling, and Synchronized in Cardiac Ventricle Tissue
Q64946420Cecal CircRNAs Are Associated With the Response to Salmonella Enterica Serovar Enteritidis Inoculation in the Chicken.
Q24294429Cell cycle control of wnt receptor activation
Q28541855Cell type-specific functions of period genes revealed by novel adipocyte and hepatocyte circadian clock models
Q39531660Cellular DBP and E4BP4 proteins are critical for determining the period length of the circadian oscillator
Q48484169Cerebellar purkinje cell loss in heterozygous rora+/- mice: a longitudinal study.
Q38572559Chrono-immunology: progress and challenges in understanding links between the circadian and immune systems
Q38065994Chronobiology in mammalian health
Q34730212Chronopharmaceutical drug delivery systems: Hurdles, hype or hope?
Q36491476CircaDB: a database of mammalian circadian gene expression profiles
Q37784519Circadian Control of Global Gene Expression Patterns
Q41224916Circadian Disruption Leads to Insulin Resistance and Obesity
Q35272978Circadian Regulation of Kisspeptin in Female Reproductive Functioning
Q37917313Circadian Rhythms, Aging, and Life Span in Mammals
Q38069757Circadian Rhythms, Metabolism, and Insulin Sensitivity: Transcriptional Networks in Animal Models
Q46794807Circadian Surprise—It's Not All About Transcription
Q35645626Circadian and CLOCK-controlled regulation of the mouse transcriptome and cell proliferation
Q55228987Circadian clock component PERIOD2 regulates diurnal expression of Na+/H+ exchanger regulatory factor-1 and its scaffolding function.
Q90310156Circadian clock genes and the transcriptional architecture of the clock mechanism
Q33486479Circadian clock genes contribute to the regulation of hair follicle cycling
Q38187003Circadian clocks and energy metabolism
Q24812340Circadian clocks are seeing the systems biology light
Q35974794Circadian control of neuroendocrine circuits regulating female reproductive function
Q43029382Circadian enhancers coordinate multiple phases of rhythmic gene transcription in vivo
Q35911874Circadian expression of clock genes in mouse macrophages, dendritic cells, and B cells
Q39020479Circadian expression of clock genes in two mosquito disease vectors: cry2 is different.
Q38615111Circadian mRNA expression: insights from modeling and transcriptomics
Q34687175Circadian organization of the mammalian retina
Q30581156Circadian pacemaking in cells and circuits of the suprachiasmatic nucleus.
Q30501017Circadian regulation of intracellular G-protein signalling mediates intercellular synchrony and rhythmicity in the suprachiasmatic nucleus
Q33784815Circadian rhythm and its role in malignancy
Q46794915Circadian rhythm of a TCA cycle enzyme is apparently regulated at the translational level in the dinoflagellate Lingulodinium polyedrum
Q33700259Circadian rhythms and addiction: mechanistic insights and future directions
Q46276021Circadian rhythms and gene expression during mouse molar tooth development
Q37774554Circadian rhythms and memory formation.
Q34555404Circadian rhythms in Neurospora crassa and other filamentous fungi
Q91666244Circadian rhythms in Per1, PER2 and Ca2+ of a solitary SCN neuron cultured on a microisland
Q38179250Circadian rhythms in leukocyte trafficking
Q38747400Circadian rhythms of liver physiology and disease: experimental and clinical evidence
Q39181594Circadian rhythms regulate amelogenesis
Q26796457Circadian systems biology: When time matters
Q36550653Circadian timing in health and disease
Q51482363Circadian transcriptional factor DBP regulates expression of Kiss1 in the anteroventral periventricular nucleus
Q34214834Circadian variations in gene expression in rat abdominal adipose tissue and relationship to physiology
Q36923742Circadian variations in rat liver gene expression: relationships to drug actions
Q42392472Clock Gene Bmal1 Modulates Human Cartilage Gene Expression by Crosstalk With Sirt1.
Q48829898Clock gene expression in human and mouse hepatic models shows similar periodicity but different dynamics of variation
Q52567354Clock gene expression in the submandibular glands.
Q38005900Clock gene variants in mood and anxiety disorders
Q36953224Clock genes may influence bipolar disorder susceptibility and dysfunctional circadian rhythm
Q46923059Clock mutation facilitates accumulation of cholesterol in the liver of mice fed a cholesterol and/or cholic acid diet
Q46201224Clock-dependent and independent transcriptional control of the two isoforms from the mouse Rorgamma gene.
Q88377323Clocking in to immunity
Q39026349Compensation for intracellular environment in expression levels of mammalian circadian clock genes
Q36361684Computational modeling of the cell-autonomous mammalian circadian oscillator
Q34576585Continuous exposure to a novel stressor based on water aversion induces abnormal circadian locomotor rhythms and sleep-wake cycles in mice
Q54332027Contribution of FSH and triiodothyronine to the development of circadian clocks during granulosa cell maturation
Q54352922Cooperation of luteinizing hormone signaling pathways in preovulatory avian follicles regulates circadian clock expression in granulosa cell
Q33290644Corticortophin releasing factor 2 receptor agonist treatment significantly slows disease progression in mdx mice
Q36755211Cross-talk between circadian clocks, sleep-wake cycles, and metabolic networks: Dispelling the darkness
Q42804134Cry1 circadian phase in vitro: wrapped up with an E-box
Q37452584Cycles in spatial and temporal chromosomal organization driven by the circadian clock
Q36799242Cyclin-dependent kinase inhibitor p20 controls circadian cell-cycle timing.
Q36211553Cycling of CRYPTOCHROME proteins is not necessary for circadian-clock function in mammalian fibroblasts
Q24321420DEC1 modulates the circadian phase of clock gene expression
Q46942289DEC2 Blocks the Effect of the ARNTL2/NPAS2 Dimer on the Expression of PER3 and DBP.
Q36055297Daily patterns of clock and cognition‐related factors are modified in the hippocampus of vitamin A‐deficient rats
Q36216462Daily rhythmicity of clock gene transcript levels in fast and slow muscle fibers from Chinese perch (Siniperca chuatsi).
Q54963535Daily variation of gene expression in diverse rat tissues.
Q36224761Design Principles of Biological Oscillators through Optimization: Forward and Reverse Analysis
Q37024388Design principles for phase-splitting behaviour of coupled cellular oscillators: clues from hamsters with 'split' circadian rhythms
Q41697412Detecting causality from nonlinear dynamics with short-term time series
Q47565457Detecting causality from short time-series data based on prediction of topologically equivalent attractors
Q41993392Detection of a circadian enhancer in the mDbp promoter using prokaryotic transposon vector-based strategy
Q52716174Diapause in a tropical oil-collecting bee: molecular basis unveiled by RNA-Seq.
Q33547409Differential expression of the circadian clock in maternal and embryonic tissues of mice
Q28593978Distinct and separable roles for endogenous CRY1 and CRY2 within the circadian molecular clockwork of the suprachiasmatic nucleus, as revealed by the Fbxl3(Afh) mutation.
Q28590986Distinct roles of DBHS family members in the circadian transcriptional feedback loop
Q41875093Disturbances in the murine hepatic circadian clock in alcohol-induced hepatic steatosis
Q37739209Diurnal and seasonal molecular rhythms in human neocortex and their relation to Alzheimer's disease
Q33407039Diurnal variation of the human adipose transcriptome and the link to metabolic disease
Q83016694Down-Regulation of Circadian Clock GenePeriod 2in Uterine Endometrial Stromal Cells of Pregnant Rats During Decidualization
Q24599500Dual roles of FBXL3 in the mammalian circadian feedback loops are important for period determination and robustness of the clock
Q37033133E4BP4 is an insulin-induced stabilizer of nuclear SREBP-1c and promotes SREBP-1c-mediated lipogenesis.
Q37164869Effect of chronic ethanol exposure on the liver of Clock-mutant mice
Q33722180Effect of feeding regimens on circadian rhythms: implications for aging and longevity
Q38954395Effect of lipopolysaccharide on circadian clock genes Per2 and Bmal1 in mouse ovary
Q51493799Effects of fasting and re-feeding on the expression of Dec1, Per1, and other clock-related genes.
Q45893124Effects of long-term microgravity exposure in space on circadian rhythms of heart rate variability
Q42368966Effects of meal composition and meal timing on the expression of genes involved in hepatic drug metabolism in rats
Q36659876Emerging evidence for the interrelationship of xenobiotic exposure and circadian rhythms: a review.
Q37999047Engineering Molecular Circuits Using Synthetic Biology in Mammalian Cells
Q28290094Entrainment of disrupted circadian behavior through inhibition of casein kinase 1 (CK1) enzymes
Q37538695Epigenetic suppression of mouse Per2 expression in the suprachiasmatic nucleus by the inhalational anesthetic, sevoflurane
Q40282051Essential role of 3'-untranslated region-mediated mRNA decay in circadian oscillations of mouse Period3 mRNA.
Q38436840Experimental and clinical aspects of melatonin and clock genes in diabetes
Q46965170Exploratory investigation of the effect of melatonin and caloric restriction on the temporal expression of murine hypothalamic transcripts
Q47227507Expression and functional analyses of circadian genes in mouse oocytes and preimplantation embryos: Cry1 is involved in the meiotic process independently of circadian clock regulation
Q50287087Expression of CLOCK
Q37246145Expression pattern of circadian genes and steroidogenesis-related genes after testosterone stimulation in the human ovary
Q34646783Extensive circadian and light regulation of the transcriptome in the malaria mosquito Anopheles gambiae
Q36220165Feedback Loops of the Mammalian Circadian Clock Constitute Repressilator.
Q24680543Feedback repression is required for mammalian circadian clock function
Q27323345Feeding Cues and Injected Nutrients Induce Acute Expression of Multiple Clock Genes in the Mouse Liver
Q33913214Flexible phase adjustment of circadian albumin D site-binding protein (DBP) gene expression by CRYPTOCHROME1
Q92609296Forward genetic approach for behavioral neuroscience using animal models
Q67228958Functional D-box sequences reset the circadian clock and drive mRNA rhythms
Q48500174Functional central rhythmicity and light entrainment, but not liver and muscle rhythmicity, are Clock independent
Q47073194Functional diversity of melanopsins and their global expression in the teleost retina
Q34447664Gene and genome parameters of mammalian liver circadian genes (LCGs).
Q33646693Gene expression profiling of the local cecal response of genetic chicken lines that differ in their susceptibility to Campylobacter jejuni colonization
Q30436629Generation of a novel allelic series of cryptochrome mutants via mutagenesis reveals residues involved in protein-protein interaction and CRY2-specific repression
Q42376218Genetic Association of the PERIOD3 (Per3) Clock Gene with Bipolar Disorder
Q37270454Genetic and neuroendocrine regulation of the postpartum brain.
Q36405856Genetic insights on sleep schedules: this time, it's PERsonal
Q37005459Genetics of Circadian Rhythms in Mammalian Model Organisms
Q27318516Genome-wide RNA polymerase II profiles and RNA accumulation reveal kinetics of transcription and associated epigenetic changes during diurnal cycles
Q104471929Genome-wide correlation analysis to identify amplitude regulators of circadian transcriptome output
Q34142933Genome-wide profiling of the core clock protein BMAL1 targets reveals a strict relationship with metabolism
Q21092423Genomic convergence among ERRα, PROX1, and BMAL1 in the control of metabolic clock outputs
Q34316534Genomics and systems approaches in the mammalian circadian clock
Q59209926Glucocorticoid signaling synchronizes the liver circadian transcriptome
Q36963269Glucocorticoid-mediated Period2 induction delays the phase of circadian rhythm
Q53555055Gonadotropic regulation of circadian clockwork in rat granulosa cells
Q37654733Heterogeneous nuclear ribonucleoprotein A1 regulates rhythmic synthesis of mouse Nfil3 protein via IRES-mediated translation
Q21999563High-throughput analysis of spatio-temporal dynamics in Dictyostelium
Q34573018Highly designable phenotypes and mutational buffers emerge from a systematic mapping between network topology and dynamic output
Q37560481How nuclear receptors tell time.
Q28591766ID2 (inhibitor of DNA binding 2) is a rhythmically expressed transcriptional repressor required for circadian clock output in mouse liver
Q33640278IL-4-induced transcription factor NFIL3/E4BP4 controls IgE class switching
Q36122122Identification of a Novel Cryptochrome Differentiating Domain Required for Feedback Repression in Circadian Clock Function
Q28274680Identification of a new clock-related element EL-box involved in circadian regulation by BMAL1/CLOCK and HES1
Q24629717Identification of functional clock-controlled elements involved in differential timing of Per1 and Per2 transcription
Q38383958Identifying Novel Transcriptional Regulators with Circadian Expression
Q33379609Implication of the F-Box Protein FBXL21 in circadian pacemaker function in mammals
Q43044922In vivo role of phosphorylation of cryptochrome 2 in the mouse circadian clock
Q27305171Increased sensitivity of the circadian system to temporal changes in the feeding regime of spontaneously hypertensive rats - a potential role for Bmal2 in the liver
Q28576407Influence of a Time-Restricted Feeding Schedule on the Daily Rhythm of abcb1a Gene Expression and Its Function in Rat Intestine
Q53644114Inhibitory role of REV-ERBα in the expression of bone morphogenetic protein gene family in rat uterus endometrium stromal cells
Q28511138Interaction of MAGED1 with nuclear receptors affects circadian clock function
Q34291433Internal Ribosomal Entry Site-Mediated Translation Is Important for Rhythmic PERIOD1 Expression
Q39384079Intestinal Expression of Mouse Abcg2/Breast Cancer Resistance Protein (BCRP) Gene Is under Control of Circadian Clock-activating Transcription Factor-4 Pathway
Q35051662Intracellular and intercellular processes determine robustness of the circadian clock.
Q26823494Involvement of the circadian rhythm and inflammatory cytokines in the pathogenesis of rheumatoid arthritis
Q30532009Involvement of urinary bladder Connexin43 and the circadian clock in coordination of diurnal micturition rhythm.
Q42803591JBIR-26, a novel natural compound from Streptomyces sp. AK-AH76, regulates mammalian circadian clock
Q33365642Judgment algorithm for periodicity of time series data based on Bayesian information criterion
Q98222237Keeping time in group 3 innate lymphoid cells
Q30476035LUX ARRHYTHMO encodes a Myb domain protein essential for circadian rhythms
Q48617460Lcg is a light-inducible and clock-controlled gene expressed in the chicken pineal gland.
Q92029478Light conditions affect rhythmic expression of aquaporin 5 and anoctamin 1 in rat submandibular glands
Q38403691Light- and circadian-controlled genes respond to a broad light spectrum in Puffer Fish-derived Fugu eye cells
Q35057088Light-dark oscillations in the lung transcriptome: implications for lung homeostasis, repair, metabolism, disease, and drug action
Q41974592Light-dependent Structural Change of Chicken Retinal Cryptochrome4
Q36005012Long-Range Chromosome Interactions Mediated by Cohesin Shape Circadian Gene Expression.
Q91867400Long-Term Effects of Altered Photoperiod During Pregnancy on Liver Gene Expression of the Progeny
Q36185967Loss of circadian clock gene expression is associated with tumor progression in breast cancer.
Q37879671MAGED1: molecular insights and clinical implications
Q36695167MBD5 haploinsufficiency is associated with sleep disturbance and disrupts circadian pathways common to Smith-Magenis and fragile X syndromes
Q97643443MRG15 orchestrates rhythmic epigenomic remodelling and controls hepatic lipid metabolism
Q38100633Mammalian Circadian Clock: The Roles of Transcriptional Repression and Delay
Q37346900Mammalian Period represses and de-represses transcription by displacing CLOCK-BMAL1 from promoters in a Cryptochrome-dependent manner
Q34273678Mammalian circadian clock and metabolism - the epigenetic link
Q36944717Mammalian circadian signaling networks and therapeutic targets.
Q30479252Mania-like behavior induced by disruption of CLOCK
Q37021702Mass spectrometry-based absolute quantification reveals rhythmic variation of mouse circadian clock proteins
Q40064213Melanopsin-dependent photo-perturbation reveals desynchronization underlying the singularity of mammalian circadian clocks
Q34358832Melatonin regulates aging and neurodegeneration through energy metabolism, epigenetics, autophagy and circadian rhythm pathways
Q41083414Messenger RNA expression of chicken CLOCK gene in the response to Campylobacter jejuni inoculation
Q99207689Metabolic rivalry: circadian homeostasis and tumorigenesis
Q92402263Microbiome diurnal rhythmicity and its impact on host physiology and disease risk
Q35843886Mining for novel candidate clock genes in the circadian regulatory network
Q33320184Modeling an evolutionary conserved circadian cis-element
Q24292897Modeling of a human circadian mutation yields insights into clock regulation by PER2
Q24305080Modulation of clock gene expression by the transcriptional coregulator receptor interacting protein 140 (RIP140)
Q28512569Molecular characterization of Mybbp1a as a co-repressor on the Period2 promoter
Q36799431Molecular circadian rhythms in central and peripheral clocks in mammals.
Q42808184Molecular mechanism of cell-autonomous circadian gene expression of Period2, a crucial regulator of the mammalian circadian clock
Q38968773Molecular modulators of the circadian clock: lessons from flies and mice
Q36374997Monitoring Cell-autonomous Circadian Clock Rhythms of Gene Expression Using Luciferase Bioluminescence Reporters
Q37041824Mouse period 2 mRNA circadian oscillation is modulated by PTB-mediated rhythmic mRNA degradation
Q47933431Multiple circadian transcriptional elements cooperatively regulate cell-autonomous transcriptional oscillation of Period3, a mammalian clock gene
Q58456851Multiple feedback loops of the Arabidopsis circadian clock provide rhythmic robustness across environmental conditions
Q34993986NFIL3/E4BP4 controls type 2 T helper cell cytokine expression
Q50350364NRF2 regulates core and stabilizing circadian clock loops, coupling redox and timekeeping in Mus musculus
Q35064303Negative feedback in the bone morphogenetic protein 4 (BMP4) synexpression group governs its dynamic signaling range and canalizes development
Q33318085Network discovery pipeline elucidates conserved time-of-day-specific cis-regulatory modules
Q36997280Neuroendocrine-immune correlates of circadian physiology: studies in experimental models of arthritis, ethanol feeding, aging, social isolation, and calorie restriction.
Q48291873Neuroglobin expression in the rat suprachiasmatic nucleus: colocalization, innervation, and response to light
Q92668133Neuronal Myocyte-Specific Enhancer Factor 2D (MEF2D) Is Required for Normal Circadian and Sleep Behavior in Mice
Q28249827Neurons and networks in daily rhythms
Q38625827New Frontiers for the NFIL3 bZIP Transcription Factor in Cancer, Metabolism and Beyond
Q92690625Non-coding cis-element of Period2 is essential for maintaining organismal circadian behaviour and body temperature rhythmicity
Q64998192Non-transcriptional processes in circadian rhythm generation.
Q58613658Norepinephrine triggers an immediate-early regulatory network response in primary human white adipocytes
Q47340286Novel transcriptional networks regulated by CLOCK in human neurons
Q34112941Nuclear envelope protein MAN1 regulates clock through BMAL1
Q34407980Nuclear receptors rock around the clock
Q37195570Obesity in mice with adipocyte-specific deletion of clock component Arntl.
Q37235010Opposing actions of Per1 and Cry2 in the regulation of Per1 target gene expression in the liver and kidney
Q24649146Oscillating perceptions: the ups and downs of the CLOCK protein in the mouse circadian system
Q36345553Pancreatic β cell enhancers regulate rhythmic transcription of genes controlling insulin secretion
Q48367057Periodic variation in bile acids controls circadian changes in uric acid via regulation of xanthine oxidase by the orphan nuclear receptor PPARα.
Q58606720Periodicity, repression, and the molecular architecture of the mammalian circadian clock
Q35224364Phenotypic robustness and the assortativity signature of human transcription factor networks
Q36939413Physiological function of PARbZip circadian clock-controlled transcription factors.
Q33810283Plasticity and specificity of the circadian epigenome
Q33886621Positive Autoregulation Delays the Expression Phase of Mammalian Clock Gene Per2
Q46304792Positive and negative factors confer phase-specific circadian regulation of transcription in Arabidopsis
Q34605395Post-translational modifications regulate the ticking of the circadian clock.
Q28652178Potential conservation of circadian clock proteins in the phylum Nematoda as revealed by bioinformatic searches
Q42848591Potential contribution of tandem circadian enhancers to nonlinear oscillations in clock gene expression
Q50610145Precision of collective oscillations in complex dynamical systems with noise
Q28591084Preferential inhibition of BMAL2-CLOCK activity by PER2 reemphasizes its negative role and a positive role of BMAL2 in the circadian transcription
Q40096655Presence of robust circadian clock oscillation under constitutive over-expression of mCry1 in rat-1 fibroblasts
Q34713996Prevalence, evolution, and cis-regulation of diel transcription in Chlamydomonas reinhardtii
Q36515720Probing the relative importance of molecular oscillations in the circadian clock
Q46190230Progesterone, but not estradiol, synchronizes circadian oscillator in the uterus endometrial stromal cells
Q42808272Proof-by-synthesis of the transcriptional logic of mammalian circadian clocks
Q24294240Prospero-related homeobox 1 (Prox1) functions as a novel modulator of retinoic acid-related orphan receptors α- and γ-mediated transactivation
Q35569525Proteomic and gene expression analysis of zebrafish brain undergoing continuous light/dark stress
Q35847051Quantifying Stochastic Noise in Cultured Circadian Reporter Cells
Q33260345Quantitative analyses of circadian gene expression in mammalian cell cultures
Q34451513REV-ERBα inhibits the PTGS2 expression in bovine uterus endometrium stromal and epithelial cells exposed to ovarian steroids
Q37385250RNA surveillance: molecular approaches in transcript quality control and their implications in clinical diseases
Q36526378RORalpha, a pivotal nuclear receptor for Purkinje neuron survival and differentiation: from development to ageing
Q28586352RORγ directly regulates the circadian expression of clock genes and downstream targets in vivo
Q33685542Ras-mediated deregulation of the circadian clock in cancer
Q39336784Real-time monitoring in three-dimensional hepatocytes reveals that insulin acts as a synchronizer for liver clock.
Q26747983Reciprocal interactions between circadian clocks and aging
Q36635907Recruitment of Histone Methyltransferase G9a Mediates Transcriptional Repression of Fgf21 Gene by E4BP4 Protein*
Q38322663Reduced histone H3K9 acetylation of clock genes and abnormal glucose metabolism in ob/ob mice.
Q21092485Redundant function of REV-ERBalpha and beta and non-essential role for Bmal1 cycling in transcriptional regulation of intracellular circadian rhythms
Q64940751Reflections on contributing to "big discoveries" about the fly clock: Our fortunate paths as post-docs with 2017 Nobel laureates Jeff Hall, Michael Rosbash, and Mike Young.
Q47976996Regional circadian period difference in the suprachiasmatic nucleus of the mammalian circadian center
Q64127896Regulation of Circadian Genes by the MAPK Pathway: Implications for Rapid Antidepressant Action
Q39412627Regulation of basic helix‐loop‐helix transcription factors Dec1 and Dec2 by RORα and their roles in adipogenesis†
Q33418304Regulation of clock-controlled genes in mammals
Q33577517Regulation of steroidogenic acute regulatory protein transcription in largemouth bass by orphan nuclear receptor signaling pathways
Q36956633Relationships between circadian rhythms and modulation of gene expression by glucocorticoids in skeletal muscle
Q33799121Remodeling of the cycling transcriptome of the oyster Crassostrea gigas by the harmful algae Alexandrium minutum.
Q48229393Removal of Rev-erbα inhibition contributes to the prostaglandin G/H synthase 2 expression in rat endometrial stromal cells.
Q58114028Requirement for NF-κB in maintenance of molecular and behavioral circadian rhythms in mice
Q33291452Resequencing PNMT in European hypertensive and normotensive individuals: no common susceptibilily variants for hypertension and purifying selection on intron 1.
Q36571294Retinoic Acid-Related Orphan Receptors (RORs): Regulatory Functions in Immunity, Development, Circadian Rhythm, and Metabolism
Q36418530Retinoic acid receptors move in time with the clock in the hippocampus. Effect of a vitamin-A-deficient diet
Q33617767Retinoic acid-related orphan receptor γ (RORγ): a novel participant in the diurnal regulation of hepatic gluconeogenesis and insulin sensitivity
Q35040936Retinoic acid-related orphan receptor γ directly regulates neuronal PAS domain protein 2 transcription in vivo
Q36562670Retinoic acid-related orphan receptors α and γ: key regulators of lipid/glucose metabolism, inflammation, and insulin sensitivity
Q34249578Retinoid acid-related orphan receptor γ, RORγ, participates in diurnal transcriptional regulation of lipid metabolic genes
Q34770626Retinoid-related Orphan Receptors (RORs): Roles in Cellular Differentiation and Development.
Q34976906Retinoid-related orphan receptors (RORs): critical roles in development, immunity, circadian rhythm, and cellular metabolism
Q34252942Rev-erb-alpha: an integrator of circadian rhythms and metabolism
Q28588540Rhythmic PER abundance defines a critical nodal point for negative feedback within the circadian clock mechanism
Q37243291Rigid Cooperation of Per1 and Per2 proteins
Q27025212Role of Nuclear Receptors in Central Nervous System Development and Associated Diseases
Q45083532Role of Rev-erbα domains for transactivation of the connexin43 promoter with Sp1.
Q24302471Role of Type II Protein Arginine Methyltransferase 5 in the Regulation of Circadian Per1 Gene
Q37233438Roles of CLOCK phosphorylation in suppression of E-box-dependent transcription
Q38658972Sleep and Anesthesia - Common mechanisms of action
Q37015528Sleep deprivation effects on circadian clock gene expression in the cerebral cortex parallel electroencephalographic differences among mouse strains
Q34062527Sleep loss reduces the DNA-binding of BMAL1, CLOCK, and NPAS2 to specific clock genes in the mouse cerebral cortex.
Q38133856Solving the mystery of human sleep schedules one mutation at a time
Q34098176Suprachiasmatic nucleus: cell autonomy and network properties
Q38092781Synthesizing Biomolecule-Based Boolean Logic Gates
Q85020125Systems Biology and Medicine: A New Take on an Old Paradigm
Q34551665Systems Biology-Derived Discoveries of Intrinsic Clocks
Q33247231Systems analysis of circadian time-dependent neuronal epidermal growth factor receptor signaling
Q36654652Systems biology of circadian rhythms: an outlook
Q34590628Systems biology of mammalian circadian clocks
Q41809497TH17 cell differentiation is regulated by the circadian clock.
Q36395819Temperature-amplitude coupling for stable biological rhythms at different temperatures
Q40170141Temporal Expression Patterns of Clock Genes and Aquaporin 5/Anoctamin 1 in Rat Submandibular Gland Cells
Q34772513The BMAL1 C terminus regulates the circadian transcription feedback loop.
Q35861542The Circadian Clock Controls Toll-like Receptor 9-Mediated Innate and Adaptive Immunity
Q36438704The Circadian Clock Modulates Enamel Development
Q87909579The Circadian Clock in White and Brown Adipose Tissue: Mechanistic, Endocrine, and Clinical Aspects
Q36966246The Circadian Clock in the Regulation of Renal Rhythms
Q59210075The Effect of Light Exposure at Night (LAN) on Carcinogenesis via Decreased Nocturnal Melatonin Synthesis
Q52727400The Genomic Landscape and Pharmacogenomic Interactions of Clock Genes in Cancer Chronotherapy.
Q92702982The Molecular Evolution of Circadian Clock Genes in Spotted Gar (Lepisosteus oculatus)
Q92501370The Poly(C) Motif in the Proximal Promoter Region of the D Site-Binding Protein Gene (Dbp) Drives Its High-Amplitude Oscillation
Q39369445The SCN Clock Governs Circadian Transcription Rhythms in Murine Epididymal White Adipose Tissue
Q98387257The SNARE Regulator Complexin3 is a Target of the Cone Circadian Clock
Q38796608The central clock controls the daily rhythm of Aqp5 expression in salivary glands
Q37071507The circadian Clock gene regulates acrosin activity of sperm through serine protease inhibitor A3K
Q37798566The circadian clock and metabolism
Q27012471The circadian clock transcriptional complex: metabolic feedback intersects with epigenetic control
Q90363031The circadian gene Nr1d1 in the mouse nucleus accumbens modulates sociability and anxiety-related behaviour
Q38055661The clock shop: coupled circadian oscillators.
Q37661538The crosstalk between physiology and circadian clock proteins
Q38982619The functional and clinical significance of the 24-hour rhythm of circulating glucocorticoids
Q39576555The harmala alkaloid harmine is a modulator of circadian Bmal1 transcription.
Q25256792The in vitro real-time oscillation monitoring system identifies potential entrainment factors for circadian clocks.
Q36373685The interplay of cis-regulatory elements rules circadian rhythms in mouse liver
Q49827006The mammalian circadian system: a hierarchical multi-oscillator structure for generating circadian rhythm.
Q28589192The mammalian clock component PERIOD2 coordinates circadian output by interaction with nuclear receptors
Q37140972The multiple facets of Per2.
Q36597665The nuclear receptor REV-ERBα represses the transcription of growth/differentiation factor 10 and 15 genes in rat endometrium stromal cells
Q37184588The nuclear receptors Rev-erbs and RORs integrate circadian rhythms and metabolism.
Q37126376The nutrigenomic investigation of C57BL/6N mice fed a short-term high-fat diet highlights early changes in clock genes expression
Q36798750The relationship between nutrition and circadian rhythms in mammals
Q39901145The resetting of the circadian rhythm by Prostaglandin J2 is distinctly phase-dependent
Q24597882The role of circadian clocks in metabolic disease
Q36752281The role of mammalian circadian proteins in normal physiology and genotoxic stress responses.
Q52604677The role of polymorphisms in circadian pathway genes in breast tumorigenesis.
Q38016990The role of the circadian clock system in nutrition and metabolism.
Q37779006The transcriptional regulator NFIL3 controls IgE production.
Q34622650Three circadian clock genes Per2, Arntl, and Npas2 contribute to winter depression
Q28580240Thyroid Transcription Factor 1, a Homeodomain Containing Transcription Factor, Contributes to Regulating Periodic Oscillations in GnRH Gene Expression
Q50067287Time for Bed: Genetic Mechanisms Mediating the Circadian Regulation of Sleep.
Q43108527Time-dependent inhibitory effect of lipopolysaccharide injection on Per1 and Per2 gene expression in the mouse heart and liver
Q37733085Timing of circadian genes in mammalian tissues.
Q21145299Timing of neuropeptide coupling determines synchrony and entrainment in the mammalian circadian clock
Q38006220Timing to Perfection: The Biology of Central and Peripheral Circadian Clocks
Q39042849Transcriptional architecture of the mammalian circadian clock
Q36348389Transcriptional regulatory logic of the diurnal cycle in the mouse liver
Q34299026Transcriptional repressor E4-binding protein 4 (E4BP4) regulates metabolic hormone fibroblast growth factor 21 (FGF21) during circadian cycles and feeding.
Q24294910Transcriptional repressor TIEG1 regulates Bmal1 gene through GC box and controls circadian clockwork
Q41034867Transition of phase response properties and singularity in the circadian limit cycle of cultured cells
Q37764168Triple-negative breast cancer: present challenges and new perspectives
Q41967486Tuning in to the rhythm of clock genes in skeletal muscle
Q34109733Tuning the mammalian circadian clock: robust synergy of two loops.
Q57041690Two coupled circadian oscillations regulate Bmal1-ELuc and Per2-SLR2 expression in the mouse suprachiasmatic nucleus
Q38954973USP2 regulates the intracellular localization of PER1 and circadian gene expression
Q30817963Universal dynamical properties preclude standard clustering in a large class of biochemical data
Q43284403Up-regulation of circadian clock gene Period 2 in the prostate mesenchymal cells during flutamide-induced apoptosis
Q36754407Usf1, a suppressor of the circadian Clock mutant, reveals the nature of the DNA-binding of the CLOCK:BMAL1 complex in mice.
Q42541521cAMP-dependent signaling as a core component of the mammalian circadian pacemaker
Q35468111hnRNP Q mediates a phase-dependent translation-coupled mRNA decay of mouse Period3
Q36506638α1B-Adrenergic receptor signaling controls circadian expression of Tnfrsf11b by regulating clock genes in osteoblasts

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