| scholarly article | Q13442814 |
| P50 | author | Richard J Weinberg | Q41881105 |
| Kimberley Tolias | Q73458885 | ||
| Dana B Harrar | Q79562059 | ||
| P2093 | author name string | Michael E Greenberg | |
| Alain Burette | |||
| Jay B Bikoff | |||
| Suzanne Paradis | |||
| Sohail Tavazoie | |||
| P433 | issue | 4 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | guanyl-nucleotide exchange factor activity | Q14860383 |
| TIAM Rac1 associated GEF 1 | Q21123942 | ||
| P304 | page(s) | 525-538 | |
| P577 | publication date | 2005-02-01 | |
| P1433 | published in | Neuron | Q3338676 |
| P1476 | title | The Rac1-GEF Tiam1 couples the NMDA receptor to the activity-dependent development of dendritic arbors and spines | |
| P478 | volume | 45 |
| Q88605066 | A Dendritic Guidance Receptor Complex Brings Together Distinct Actin Regulators to Drive Efficient F-Actin Assembly and Branching |
| Q35642080 | A TRPC5-regulated calcium signaling pathway controls dendrite patterning in the mammalian brain |
| Q30435355 | A central role for the small GTPase Rac1 in hippocampal plasticity and spatial learning and memory |
| Q38759007 | A dual role for the RhoGEF Ephexin5 in regulation of dendritic spine outgrowth |
| Q37461805 | A gene trap knockout of the Tiam-1 protein results in malformation of the early embryonic brain |
| Q36908985 | A genome-wide screen of CREB occupancy identifies the RhoA inhibitors Par6C and Rnd3 as regulators of BDNF-induced synaptogenesis. |
| Q28572398 | A novel family of adhesion-like molecules that interacts with the NMDA receptor |
| Q36294402 | A role for kalirin in the response of rat medium spiny neurons to cocaine |
| Q92655599 | A sex difference in the response of the rodent postsynaptic density to synGAP haploinsufficiency |
| Q38513796 | ADF/cofilin: a crucial regulator of synapse physiology and behavior |
| Q37089844 | AMPA receptor and GEF-H1/Lfc complex regulates dendritic spine development through RhoA signaling cascade |
| Q57810465 | ATP7A and ATP7B copper transporters have distinct functions in the regulation of neuronal DOPAMINE-β-HYDROXYLASE |
| Q46401592 | Aberrant calcium/calmodulin-dependent protein kinase II (CaMKII) activity is associated with abnormal dendritic spine morphology in the ATRX mutant mouse brain. |
| Q28066333 | Actin-Dependent Alterations of Dendritic Spine Morphology in Shankopathies |
| Q54978931 | Activation of EphB2 Forward Signaling Enhances Memory Consolidation. |
| Q24306062 | Activity-dependent synaptogenesis: regulation by a CaM-kinase kinase/CaM-kinase I/betaPIX signaling complex |
| Q39004707 | Adhesion GPCRs as Novel Actors in Neural and Glial Cell Functions: From Synaptogenesis to Myelination |
| Q35130800 | Akt1 deficiency affects neuronal morphology and predisposes to abnormalities in prefrontal cortex functioning |
| Q35036532 | Alterations to dendritic spine morphology, but not dendrite patterning, of cortical projection neurons in Tc1 and Ts1Rhr mouse models of Down syndrome |
| Q48452284 | Altered signaling pathways underlying abnormal hippocampal synaptic plasticity in the Ts65Dn mouse model of Down syndrome |
| Q84951271 | An Image Driven Systems Biology Approach for Neurodegenerative Disease Studies in the TSC-mTOR Pathway |
| Q24302459 | An OBSL1-Cul7Fbxw8 ubiquitin ligase signaling mechanism regulates Golgi morphology and dendrite patterning |
| Q24645518 | An activity-regulated microRNA controls dendritic plasticity by down-regulating p250GAP |
| Q48107776 | An early critical period for long-term plasticity and structural modification of sensory synapses in olfactory cortex. |
| Q28564696 | An essential role for the integrin-linked kinase-glycogen synthase kinase-3 beta pathway during dendrite initiation and growth |
| Q33714892 | Antillatoxin, a novel lipopeptide, enhances neurite outgrowth in immature cerebrocortical neurons through activation of voltage-gated sodium channels |
| Q46915310 | Arc/Arg3.1 translation is controlled by convergent N-methyl-D-aspartate and Gs-coupled receptor signaling pathways |
| Q36682364 | Bidirectional ephrin/Eph signaling in synaptic functions |
| Q37333581 | Bidirectional modulation of synaptic functions by Eph/ephrin signaling. |
| Q90504240 | Branching mechanisms shaping dendrite architecture |
| Q34241648 | CNF1 improves astrocytic ability to support neuronal growth and differentiation in vitro. |
| Q41953827 | CaMKII Phosphorylation of TARPγ-8 Is a Mediator of LTP and Learning and Memory. |
| Q34203749 | Calcium signaling in synapse-to-nucleus communication |
| Q33748403 | Carboxypeptidase E knockout mice exhibit abnormal dendritic arborization and spine morphology in central nervous system neurons. |
| Q34591249 | Casein kinase 2 phosphorylation of protein kinase C and casein kinase 2 substrate in neurons (PACSIN) 1 protein regulates neuronal spine formation |
| Q28582482 | Cdk5 regulates EphA4-mediated dendritic spine retraction through an ephexin1-dependent mechanism |
| Q37323619 | Cell-intrinsic drivers of dendrite morphogenesis |
| Q41107282 | Chronic Kappa opioid receptor activation modulates NR2B: Implication in treatment resistant depression |
| Q93137788 | Conditional Deletion of CC2D1A Reduces Hippocampal Synaptic Plasticity and Impairs Cognitive Function through Rac1 Hyperactivation |
| Q26753846 | Control of Dendritic Spine Morphological and Functional Plasticity by Small GTPases |
| Q35103359 | Control of interneuron dendritic growth through NRG1/erbB4-mediated kalirin-7 disinhibition |
| Q35084942 | Control of synapse development and plasticity by Rho GTPase regulatory proteins. |
| Q37981628 | Deconstructing signal transduction pathways that regulate the actin cytoskeleton in dendritic spines |
| Q37865048 | Dendrite remodeling in development and disease |
| Q38175135 | Dendritic spines: the locus of structural and functional plasticity |
| Q36595699 | Differential Rac1 signalling by guanine nucleotide exchange factors implicates FLII in regulating Rac1-driven cell migration |
| Q34727327 | Differential Tiam1/Rac1 activation in hippocampal and cortical neurons mediates differential spine shrinkage in response to oxygen/glucose deprivation. |
| Q47094875 | Differential regulation of the Rac1 GTPase-activating protein (GAP) BCR during oxygen/glucose deprivation in hippocampal and cortical neurons |
| Q28583457 | Disrupted-in-Schizophrenia 1 (DISC1) regulates spines of the glutamate synapse via Rac1 |
| Q33782157 | Distinct ligand specificity of the Tiam1 and Tiam2 PDZ domains |
| Q33951240 | Dynamic control of excitatory synapse development by a Rac1 GEF/GAP regulatory complex |
| Q26765596 | Emerging Roles of BAI Adhesion-GPCRs in Synapse Development and Plasticity |
| Q43122416 | Enhancement of Amygdaloid Neuronal Dendritic Arborization by Fresh Leaf Juice of Centella asiatica (Linn) During Growth Spurt Period in Rats |
| Q37087056 | Eph/ephrin signaling: networks. |
| Q34267791 | EphA3 functions are regulated by collaborating phosphotyrosine residues |
| Q28592406 | EphB receptors regulate dendritic spine morphogenesis through the recruitment/phosphorylation of focal adhesion kinase and RhoA activation |
| Q24304584 | EphB-mediated degradation of the RhoA GEF Ephexin5 relieves a developmental brake on excitatory synapse formation |
| Q81150017 | EphB2 gets a GRIP on the dendritic arbor |
| Q26863347 | EphBs: an integral link between synaptic function and synaptopathies |
| Q35245788 | Essential role for vav Guanine nucleotide exchange factors in brain-derived neurotrophic factor-induced dendritic spine growth and synapse plasticity |
| Q50772094 | Evaluation of amygdaloid neuronal dendritic arborization enhancing effect of Centella asiatica (Linn) fresh leaf extract in adult rats. |
| Q61814303 | Fragile-X Syndrome Is Associated With NMDA Receptor Hypofunction and Reduced Dendritic Complexity in Mature Dentate Granule Cells |
| Q42290463 | From neuronal activity to the actin cytoskeleton: a role for CaMKKs and betaPIX in spine morphogenesis |
| Q36001321 | Gene regulation via excitation and BDNF is mediated by induction and phosphorylation of the Etv1 transcription factor in cerebellar granule cells |
| Q33669877 | Genome-wide methylation analysis of a large population sample shows neurological pathways involvement in chronic widespread musculoskeletal pain |
| Q89824747 | Genomic analyses reveal distinct genetic architectures and selective pressures in buffaloes |
| Q37409554 | GluN3A expression restricts spine maturation via inhibition of GIT1/Rac1 signaling. |
| Q46852219 | GluR1 links structural and functional plasticity at excitatory synapses. |
| Q30536297 | Hippocampal phenotypes in kalirin-deficient mice |
| Q42323220 | Human Rho Guanine Nucleotide Exchange Factor 11 (ARHGEF11) Regulates Dendritic Morphogenesis |
| Q26798113 | IRSp53/BAIAP2 in dendritic spine development, NMDA receptor regulation, and psychiatric disorders |
| Q35023882 | Identification of kalirin-7 as a potential post-synaptic density signaling hub |
| Q36070659 | Induction of dendritic spines by β2-containing nicotinic receptors. |
| Q24314537 | Inositol 1,4,5-trisphosphate 3-kinase a functions as a scaffold for synaptic Rac signaling |
| Q37709539 | Insulin receptor signaling in the development of neuronal structure and function. |
| Q36146950 | Integration of biochemical signalling in spines |
| Q46935402 | Integrins control dendritic spine plasticity in hippocampal neurons through NMDA receptor and Ca2+/calmodulin-dependent protein kinase II-mediated actin reorganization. |
| Q36646322 | Kalirin and Trio proteins serve critical roles in excitatory synaptic transmission and LTP. |
| Q28509168 | Kalirin binds the NR2B subunit of the NMDA receptor, altering its synaptic localization and function |
| Q24677936 | Kalirin-7 controls activity-dependent structural and functional plasticity of dendritic spines |
| Q36942813 | Kalirin-7 is an essential component of both shaft and spine excitatory synapses in hippocampal interneurons |
| Q64262809 | LPM580098, a Novel Triple Reuptake Inhibitor of Serotonin, Noradrenaline, and Dopamine, Attenuates Neuropathic Pain |
| Q44629164 | LTP-induced long-term stabilization of individual nascent dendritic spines. |
| Q37118913 | Maturation and integration of adult born hippocampal neurons: signal convergence onto small Rho GTPases |
| Q28081571 | Mechanisms for spatiotemporal regulation of Rho-GTPase signaling at synapses |
| Q39452587 | Mechanisms regulating dendritic arbor patterning |
| Q47981657 | Memantine prevents acute radiation-induced toxicities at hippocampal excitatory synapses. |
| Q92786376 | MiR-190a potentially ameliorates postoperative cognitive dysfunction by regulating Tiam1 |
| Q39242448 | Microtubule-associated protein 1B (MAP1B) is required for dendritic spine development and synaptic maturation |
| Q26851882 | Molecular mechanisms of activity-dependent changes in dendritic morphology: role of RGK proteins |
| Q37179196 | Molecular responses of the Ts65Dn and Ts1Cje mouse models of Down syndrome to MK-801. |
| Q36961186 | Morphogenic signaling in neurons via neurotransmitter receptors and small GTPases |
| Q36051327 | NMDA receptor activation induces translocation and activation of Rac in mouse hippocampal area CA1 |
| Q28580426 | NMDA receptor couples Rac1-GEF Tiam1 to direct oligodendrocyte precursor cell migration |
| Q34535739 | NMDA receptor-dependent regulation of dendritic spine morphology by SAP102 splice variants |
| Q37589859 | Neuronal Rho GEFs in synaptic physiology and behavior |
| Q48006757 | Neuronal cytoskeletal gene dysregulation and mechanical hypersensitivity in a rat model of Rett syndrome. |
| Q36494331 | Neuroproteomics - the tasks lying ahead |
| Q90575301 | Neurotropic and modulatory effects of insulin-like growth factor II in Aplysia |
| Q34781716 | New functions and signaling mechanisms for the class of adhesion G protein-coupled receptors. |
| Q37372485 | Organization and dynamics of PDZ-domain-related supramodules in the postsynaptic density |
| Q38815063 | Organization and dynamics of the actin cytoskeleton during dendritic spine morphological remodeling |
| Q24318480 | PAK signalling in neuronal physiology |
| Q40781777 | PAR3-aPKC regulates Tiam1 by modulating suppressive internal interactions |
| Q90349337 | Planar cell polarity gene Fuz triggers apoptosis in neurodegenerative disease models |
| Q30486698 | Polarized signaling endosomes coordinate BDNF-induced chemotaxis of cerebellar precursors. |
| Q93379630 | Prefrontal cortical trkB, glucocorticoids, and their interactions in stress and developmental contexts |
| Q48507439 | Preso regulation of dendritic outgrowth through PI(4,5)P2-dependent PDZ interaction with βPix |
| Q35745858 | Propofol neurotoxicity is mediated by p75 neurotrophin receptor activation |
| Q22252566 | Prospects for Improving Brain Function in Individuals with Down Syndrome |
| Q35202586 | Protein dynamics associated with failed and rescued learning in the Ts65Dn mouse model of Down syndrome |
| Q37687443 | Protein profiles associated with context fear conditioning and their modulation by memantine |
| Q34324347 | Protein profiles in Tc1 mice implicate novel pathway perturbations in the Down syndrome brain |
| Q35847315 | RabGEF1/Rabex-5 Regulates TrkA-Mediated Neurite Outgrowth and NMDA-Induced Signaling Activation in NGF-Differentiated PC12 Cells |
| Q36849290 | Rac GEF Dock4 interacts with cortactin to regulate dendritic spine formation |
| Q48693374 | Rac1 induces the clustering of AMPA receptors during spinogenesis. |
| Q27306257 | Rapid dispersion of SynGAP from synaptic spines triggers AMPA receptor insertion and spine enlargement during LTP. |
| Q37143525 | RasGRF2 Rac-GEF activity couples NMDA receptor calcium flux to enhanced synaptic transmission |
| Q39329885 | Regulating Rac in the nervous system: molecular function and disease implication of Rac GEFs and GAPs. |
| Q45743384 | Regulation of dendritic spine morphology by an NMDA receptor-associated Rho GTPase-activating protein, p250GAP. |
| Q37629022 | Regulation of spine and synapse formation by activity-dependent intracellular signaling pathways |
| Q28581637 | Regulation of spine density and morphology by IQGAP1 protein domains |
| Q37361588 | Regulation of synaptic Rac1 activity, long-term potentiation maintenance, and learning and memory by BCR and ABR Rac GTPase-activating proteins. |
| Q37986650 | Regulation of the actin cytoskeleton in dendritic spines |
| Q35985886 | Requirement of JIP scaffold proteins for NMDA-mediated signal transduction |
| Q48547144 | Rho family GTPase inhibition reveals opposing effects of mitogen-activated protein kinase kinase/extracellular signal-regulated kinase and Janus kinase/signal transducer and activator of transcription signaling cascades on neuronal survival |
| Q38919082 | RhoGTPases at the synapse: An embarrassment of choice |
| Q48812120 | Role of GluN2A and GluN2B subunits in the formation of filopodia and secondary dendrites in cultured hippocampal neurons |
| Q37241059 | Role of Rac1 GTPase in JNK signaling and delayed neuronal cell death following global cerebral ischemia |
| Q24541317 | Role of numb in dendritic spine development with a Cdc42 GEF intersectin and EphB2. |
| Q33885377 | Scaffold proteins IRSp53 and spinophilin regulate localized Rac activation by T-lymphocyte invasion and metastasis protein 1 (TIAM1). |
| Q28576940 | Selective targeting of the gamma1 isoform of protein phosphatase 1 to F-actin in intact cells requires multiple domains in spinophilin and neurabin |
| Q61818177 | Sex-Specific Gene Expression in the Mouse Nucleus Accumbens Before and After Cocaine Exposure |
| Q28575579 | Shank3 deficiency induces NMDA receptor hypofunction via an actin-dependent mechanism |
| Q37471826 | Sigma-1 receptors regulate hippocampal dendritic spine formation via a free radical-sensitive mechanism involving Rac1xGTP pathway |
| Q48215083 | Signaling via dopamine D1 and D3 receptors oppositely regulates cocaine-induced structural remodeling of dendrites and spines |
| Q37195883 | Sodium channel activation augments NMDA receptor function and promotes neurite outgrowth in immature cerebrocortical neurons |
| Q28570707 | Subcellular localization of Patched and Smoothened, the receptors for Sonic hedgehog signaling, in the hippocampal neuron |
| Q43567128 | Supralinear dendritic Ca(2+) signalling in young developing CA1 pyramidal cells |
| Q43211225 | SynGAP regulates steady-state and activity-dependent phosphorylation of cofilin. |
| Q38174853 | Synaptic Signaling in Learning and Memory |
| Q37764703 | Synaptic plasticity, a symphony in GEF. |
| Q36851341 | Synthesis and structure activity relationship of tetrahydroisoquinoline-based potentiators of GluN2C and GluN2D containing N-methyl-D-aspartate receptors |
| Q61806923 | TIAM-1/GEF can shape somatosensory dendrites independently of its GEF activity by regulating F-actin localization |
| Q39309086 | TRPC Channel Downstream Signaling Cascades. |
| Q34795242 | Targeting ligand-operated chaperone sigma-1 receptors in the treatment of neuropsychiatric disorders |
| Q38008295 | The Ca2+ and Rho GTPase signaling pathways underlying activity-dependent actin remodeling at dendritic spines. |
| Q41349794 | The E3 ubiquitin ligase IDOL regulates synaptic ApoER2 levels and is important for plasticity and learning |
| Q38366331 | The GTPase Rem2 regulates synapse development and dendritic morphology |
| Q24314777 | The PHCCEx domain of Tiam1/2 is a novel protein- and membrane-binding module |
| Q30494105 | The Rac activator STEF (Tiam2) regulates cell migration by microtubule-mediated focal adhesion disassembly |
| Q37387817 | The Rac-GAP Bcr is a novel regulator of the Par complex that controls cell polarity. |
| Q39685886 | The Rac-GAP alpha2-chimaerin regulates hippocampal dendrite and spine morphogenesis |
| Q35758529 | The Rac1 guanine nucleotide exchange factor Tiam1 mediates EphB receptor-dependent dendritic spine development |
| Q34345666 | The Rac1 inhibitor NSC23766 suppresses CREB signaling by targeting NMDA receptor function. |
| Q34559555 | The Ras-GRF1 exchange factor coordinates activation of H-Ras and Rac1 to control neuronal morphology |
| Q28594950 | The Rho-specific GEF Lfc interacts with neurabin and spinophilin to regulate dendritic spine morphology |
| Q30424414 | The RhoG/ELMO1/Dock180 signaling module is required for spine morphogenesis in hippocampal neurons. |
| Q28771510 | The RhoGEF DOCK10 is essential for dendritic spine morphogenesis |
| Q26786905 | The Role of Ephs and Ephrins in Memory Formation |
| Q94502452 | The Role of Rac GTPase in Dendritic Spine Morphogenesis and Memory |
| Q47689634 | The Small GTPase Rac1 Contributes to Extinction of Aversive Memories of Drug Withdrawal by Facilitating GABAA Receptor Endocytosis in the vmPFC. |
| Q24305474 | The Tiam1 PDZ domain couples to Syndecan1 and promotes cell-matrix adhesion |
| Q33940362 | The addicted synapse: mechanisms of synaptic and structural plasticity in nucleus accumbens. |
| Q28571945 | The adhesion-GPCR BAI1 regulates synaptogenesis by controlling the recruitment of the Par3/Tiam1 polarity complex to synaptic sites |
| Q27316421 | The calcium sensor Copine-6 regulates spine structural plasticity and learning and memory |
| Q37457447 | The cell biology of synaptic specificity during development |
| Q24541445 | The diacylglycerol-binding protein alpha1-chimaerin regulates dendritic morphology |
| Q35451156 | The guanine nucleotide exchange factor (GEF) Asef2 promotes dendritic spine formation via Rac activation and spinophilin-dependent targeting |
| Q35781674 | The neural EGF family member CALEB/NGC mediates dendritic tree and spine complexity |
| Q28575724 | The nogo receptor family restricts synapse number in the developing hippocampus |
| Q28568832 | The nonkinase phorbol ester receptor alpha 1-chimerin binds the NMDA receptor NR2A subunit and regulates dendritic spine density |
| Q28574621 | The polarity protein PAR-3 and TIAM1 cooperate in dendritic spine morphogenesis |
| Q30827488 | The pseudokinase CaMKv is required for the activity-dependent maintenance of dendritic spines. |
| Q36106428 | The role of GluN2A and GluN2B NMDA receptor subunits in AgRP and POMC neurons on body weight and glucose homeostasis |
| Q41828232 | The transcription factor XBP1 in memory and cognition: Implications in Alzheimer disease |
| Q37318794 | The yin-yang of dendrite morphology: unity of actin and microtubules. |
| Q28574787 | Tiam1 as a signaling mediator of nerve growth factor-dependent neurite outgrowth |
| Q90616382 | Tiam1 is Critical for Glutamatergic Synapse Structure and Function in the Hippocampus |
| Q28116790 | Tiam1 regulates the Wnt/Dvl/Rac1 signaling pathway and the differentiation of midbrain dopaminergic neurons |
| Q39722145 | Tiam1-Rac signaling counteracts Eg5 during bipolar spindle assembly to facilitate chromosome congression |
| Q30495861 | Trio is a key guanine nucleotide exchange factor coordinating regulation of the migration and morphogenesis of granule cells in the developing cerebellum |
| Q28505203 | TrkB binds and tyrosine-phosphorylates Tiam1, leading to activation of Rac1 and induction of changes in cellular morphology |
| Q48336985 | TrkB phosphorylation by Cdk5 is required for activity-dependent structural plasticity and spatial memory. |
| Q28583900 | TrkB-mediated activation of geranylgeranyltransferase I promotes dendritic morphogenesis |
| Q38144624 | Tubulin, actin and heterotrimeric G proteins: coordination of signaling and structure |
| Q37987406 | Ultrastructure of synapses in the mammalian brain |
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| Q37612461 | Wnt5a is essential for hippocampal dendritic maintenance and spatial learning and memory in adult mice |
| Q39553219 | mTORC2 controls actin polymerization required for consolidation of long-term memory. |
| Q50287748 | p-TIAM1 exchanges GTP for GDP on RAC1, activating it |
| Q37154492 | p21-Activated kinase mediates rapid estradiol-negative feedback actions in the reproductive axis |
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| Q34467645 | p75 regulates Purkinje cell firing by modulating SK channel activity through Rac1. |
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