Extensive brain hemorrhage and embryonic lethality in a mouse null mutant of CREB-binding protein

scientific article (publication date: July 2000)

Extensive brain hemorrhage and embryonic lethality in a mouse null mutant of CREB-binding protein is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/S0925-4773(00)00360-9
P3181OpenCitations bibliographic resource ID1276688
P698PubMed publication ID10906457
P5875ResearchGate publication ID12413899

P50authorShunsuke IshiiQ55297655
P2093author name stringM Xu
Y Tanaka
T Maekawa
T Nakahata
T Hongo
I Naruse
P2860cites workSonic Hedgehog-induced activation of the Gli1 promoter is mediated by GLI3Q22009022
Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloningQ24310148
Mutations in TWIST, a basic helix-loop-helix transcription factor, in Saethre-Chotzen syndromeQ24311679
Mutations of the TWIST gene in the Saethre-Chotzen syndromeQ24311736
Activation of cAMP and mitogen responsive genes relies on a common nuclear factorQ24313652
Histone-like TAFs within the PCAF histone acetylase complexQ24317520
The translocation t(8;16)(p11;p13) of acute myeloid leukaemia fuses a putative acetyltransferase to the CREB-binding proteinQ24318775
Nuclear protein CBP is a coactivator for the transcription factor CREBQ24319801
Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300Q24324556
A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1AQ24336667
Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domainQ27860534
A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptorsQ27860552
The transcriptional coactivators p300 and CBP are histone acetyltransferasesQ27860843
A subset of TAF(II)s are integral components of the SAGA complex required for nucleosome acetylation and transcriptional stimulationQ27936635
The CBP co-activator is a histone acetyltransferaseQ28131758
Dorso-ventral and rostro-caudal sequential expression of M-twist in the postimplantation murine embryo.Q52208238
Drosophila CBP represses the transcription factor TCF to antagonize Wingless signalling.Q52566206
GLI3 zinc-finger gene interrupted by translocations in Greig syndrome familiesQ55670532
A family of transcriptional adaptor proteins targeted by the E1A oncoproteinQ59070933
Adenoviral ElA-associated protein p300 as a functional homologue of the transcriptional co-activator CBPQ59095054
CBP as a transcriptional coactivator of c-MybQ64382929
Cephalic neurulation and optic vesicle formation in the early mouse embryoQ66936792
Clonal origin of murine hemopoietic colonies with apparent restriction to granuclocyte-macrophage-megakaryocyte (GMM) differentiationQ70403278
RNA helicase A mediates association of CBP with RNA polymerase IIQ28250576
Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alphaQ28259513
Phosphorylated CREB binds specifically to the nuclear protein CBPQ28265019
Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300Q28270979
AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesisQ28273478
The M-twist gene of Mus is expressed in subsets of mesodermal cells and is closely related to the Xenopus X-twi and the Drosophila twist genesQ28276195
Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptorQ28286827
The signal-dependent coactivator CBP is a nuclear target for pp90RSKQ28286828
Cooperation of Stat2 and p300/CBP in signalling induced by interferon-alphaQ28292603
Rubinstein-Taybi syndrome caused by mutations in the transcriptional co-activator CBPQ28295041
Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesisQ28300359
twist is required in head mesenchyme for cranial neural tube morphogenesisQ28590860
The winged helix transcription factor MFH1 is required for proliferation and patterning of paraxial mesoderm in the mouse embryoQ28591300
Hematopoiesis in the fetal liver is impaired by targeted mutagenesis of a gene encoding a non-DNA binding subunit of the transcription factor, polyomavirus enhancer binding protein 2/core binding factorQ28594445
An essential role for p300/CBP in the cellular response to hypoxiaQ28678439
Regulation of transcription by hypoxia requires a multiprotein complex that includes hypoxia-inducible factor 1, an adjacent transcription factor, and p300/CREB binding proteinQ28678484
Role of CBP/P300 in nuclear receptor signallingQ29616443
Interaction and functional cooperation of the leukemia-associated factors AML1 and p300 in myeloid cell differentiationQ33888879
Broad thumbs and toes and facial abnormalities. A possible mental retardation syndromeQ33971011
CREB-binding protein cooperates with transcription factor GATA-1 and is required for erythroid differentiationQ35901820
MLL is fused to CBP, a histone acetyltransferase, in therapy-related acute myeloid leukemia with a t(11;16)(q23;p13.3).Q36556977
Abnormal skeletal patterning in embryos lacking a single Cbp allele: a partial similarity with Rubinstein-Taybi syndrome.Q36584466
Truncated CBP protein leads to classical Rubinstein-Taybi syndrome phenotypes in mice: implications for a dominant-negative mechanismQ38328546
The dorsal morphogen gradient regulates the mesoderm determinant twist in early Drosophila embryosQ38333258
Interaction of the co-activator CBP with Myb proteins: effects on Myb-specific transactivation and on the cooperativity with NF-MQ41065257
Regulation of NF-kappaB by cyclin-dependent kinases associated with the p300 coactivatorQ41133317
Neurulation in the mouse: manner and timing of neural tube closureQ41243746
A novel ES cell line, TT2, with high germline-differentiating potencyQ41524060
Interaction and functional collaboration of p300/CBP and bHLH proteins in muscle and B-cell differentiationQ42808711
Regulation of activity of the transcription factor GATA-1 by acetylationQ42823439
Acetylation of HMG I(Y) by CBP turns off IFN beta expression by disrupting the enhanceosomeQ44646118
The CBFbeta subunit is essential for CBFalpha2 (AML1) function in vivoQ45345510
Functional analysis of the Drosophila twist promoter reveals a dorsal-binding ventral activator regionQ46065140
Sequence-specific transactivation of the Drosophila twist gene by the dorsal gene productQ47070839
Drosophila CBP is a co-activator of cubitus interruptus in hedgehog signallingQ47072204
Conjunction dysfunction: CBP/p300 in human disease.Q48013074
Closure of the neural tube in the cephalic region of the mouse embryoQ48247586
Drosophila CBP is required for dorsal-dependent twist gene expression.Q52192359
Sending and receiving the hedgehog signal: control by the Drosophila Gli protein Cubitus interruptus.Q52201064
Expression of M-twist during postimplantation development of the mouse.Q52205008
P433issue1-2
P407language of work or nameEnglishQ1860
P921main subjectbrainQ1073
bleedingQ166019
P304page(s)133-145
P577publication date2000-07-01
P1433published inMechanisms of DevelopmentQ6804657
P1476titleExtensive brain hemorrhage and embryonic lethality in a mouse null mutant of CREB-binding protein
P478volume95

Reverse relations

cites work (P2860)
Q38766912A Small Molecule Activator of p300/CBP Histone Acetyltransferase Promotes Survival and Neurite Growth in a Cellular Model of Parkinson's Disease.
Q30357571A TDG/CBP/RARα ternary complex mediates the retinoic acid-dependent expression of DNA methylation-sensitive genes
Q36349016A unique missense allele of BAF155, a core BAF chromatin remodeling complex protein, causes neural tube closure defects in mice
Q39598834Ablation of CBP in forebrain principal neurons causes modest memory and transcriptional defects and a dramatic reduction of histone acetylation but does not affect cell viability
Q37249167Acetyltransferases (HATs) as targets for neurological therapeutics
Q44225326Age-related changes in CREB binding protein immunoreactivity in the cerebral cortex and hippocampus of rats
Q41993123Amphipathic small molecules mimic the binding mode and function of endogenous transcription factors
Q37140791An overview of nuclear receptor coregulators involved in cerebellar development
Q37935915Bromodomains as therapeutic targets
Q58721602CBP and P300 regulate distinct gene networks required for human primary myoblast differentiation and muscle integrity
Q92237346CBP and SRF co-regulate dendritic growth and synaptic maturation
Q30436207CBP and p300 are essential for renin cell identity and morphological integrity of the kidney
Q37352828CBP/p300 and associated transcriptional co-activators exhibit distinct expression patterns during murine craniofacial and neural tube development
Q38340711CBP/p300 double null cells reveal effect of coactivator level and diversity on CREB transactivation
Q34080062Characterization of an antagonistic switch between histone H3 lysine 27 methylation and acetylation in the transcriptional regulation of Polycomb group target genes
Q34327866Chromatin acetylation, memory, and LTP are impaired in CBP+/- mice: a model for the cognitive deficit in Rubinstein-Taybi syndrome and its amelioration.
Q38151696Chromatin-based epigenetics of adult subventricular zone neural stem cells
Q33593991Complex regulation of the transactivation function of hypoxia-inducible factor-1 alpha by direct interaction with two distinct domains of the CREB-binding protein/p300.
Q38208728Crafting the brain - role of histone acetyltransferases in neural development and disease.
Q37688395Crucial roles of histone-modifying enzymes in mediating neural cell-type specification
Q38037625DNA demethylation by TDG.
Q28591430Differential role of p300 and CBP acetyltransferase during myogenesis: p300 acts upstream of MyoD and Myf5
Q28589003Disruption of Sept6, a fusion partner gene of MLL, does not affect ontogeny, leukemogenesis induced by MLL-SEPT6, or phenotype induced by the loss of Sept4.
Q34379557Distinct roles for CREB-binding protein and p300 in hematopoietic stem cell self-renewal
Q33522839Diversity of mechanisms involved in aromatase regulation and estrogen action in the brain
Q47423681Epigenetic Etiology of Intellectual Disability
Q26748876Epigenetic Mechanisms in Developmental Alcohol-Induced Neurobehavioral Deficits
Q50421076Epigenetic modifiers promote mitochondrial biogenesis and oxidative metabolism leading to enhanced differentiation of neuroprogenitor cells.
Q34747263Epigenetic programming of hypoxic-ischemic encephalopathy in response to fetal hypoxia
Q34449181Epigenetic regulation of cardiac myocyte differentiation.
Q24672302Essential function of p300 acetyltransferase activity in heart, lung and small intestine formation
Q39067631Functions of bromodomain-containing proteins and their roles in homeostasis and cancer.
Q26996782Gene-environment interactions in severe intraventricular hemorrhage of preterm neonates
Q44296681Generation of a conditional allele of the CBP gene in mouse
Q33713299Genes encoding critical transcriptional activators for murine neural tube development and human spina bifida: a case-control study
Q64246563Genetic Association of Phosphodiesterases With Human Cognitive Performance
Q28593439Genetic ablation of the steroid receptor coactivator-ubiquitin ligase, E6-AP, results in tissue-selective steroid hormone resistance and defects in reproduction
Q24556629Genetic deletion of the repressor of estrogen receptor activity (REA) enhances the response to estrogen in target tissues in vivo
Q28536743Genetic interaction between mutations in c-Myb and the KIX domains of CBP and p300 affects multiple blood cell lineages and influences both gene activation and repression
Q34552276Genetics and development of neural tube defects.
Q34122513Genome-wide assessment of differential roles for p300 and CBP in transcription regulation
Q53290791Genome-wide association study identifies a new susceptibility locus for cleft lip with or without a cleft palate.
Q24685650Global transcriptional coactivators CREB-binding protein and p300 are highly essential collectively but not individually in peripheral B cells
Q37247908Histone acetyltransferase CBP is vital to demarcate conventional and innate CD8+ T-cell development
Q28585449Histone acetyltransferase activities of cAMP-regulated enhancer-binding protein and p300 in tissues of fetal, young, and old mice
Q26745642Histone acetyltransferases: challenges in targeting bi-substrate enzymes
Q37528712Histone posttranslational modifications and cell fate determination: lens induction requires the lysine acetyltransferases CBP and p300.
Q42524420Identification of p300-targeted acetylated residues in GATA4 during hypertrophic responses in cardiac myocytes
Q87904878Identification of transcripts potentially involved in neural tube closure using RNA sequencing
Q28566098Interaction between the HPV E7 oncoprotein and the transcriptional coactivator p300
Q38364553Intrinsic regulations in neural fate commitment.
Q36021885Is histone acetylation the most important physiological function for CBP and p300?
Q97565930KLF3 Mediates Epidermal Differentiation through the Epigenomic Writer CBP
Q39747094KLF8 recruits the p300 and PCAF co-activators to its amino terminal activation domain to activate transcription
Q47395308Loss of p300 and CBP disrupts histone acetylation at the mouse Sry promoter and causes XY gonadal sex reversal.
Q38085375Lysine acetyltransferases CBP and p300 as therapeutic targets in cognitive and neurodegenerative disorders.
Q36970331MOF maintains transcriptional programs regulating cellular stress response.
Q28567072NF-Y is essential for expression of the proapoptotic bim gene in sympathetic neurons
Q36012078Nuclear receptor coregulators are new players in nervous system development and function
Q33193939Quantitative analysis of CBP- and P300-induced histone acetylations in vivo using native chromatin.
Q73443708Reactive astrocytes express cAMP-response-element-binding protein (CREB) binding protein (CBP) in the central nervous system of transgenic mice expressing a human Cu/Zn superoxide dismutase mutation
Q39838387Retinoid signaling and neurogenin2 function are coupled for the specification of spinal motor neurons through a chromatin modifier CBP
Q24300183Roles of HIPK1 and HIPK2 in AML1- and p300-dependent transcription, hematopoiesis and blood vessel formation
Q46134600Rubinstein-Taybi Syndrome and Epigenetic Alterations.
Q36973859Rubinstein-Taybi syndrome: clinical and molecular overview
Q32874823Setd5 is essential for mammalian development and the co-transcriptional regulation of histone acetylation
Q38867041Small-molecule inhibition of CBP/catenin interactions eliminates drug-resistant clones in acute lymphoblastic leukemia
Q34692024Small-molecule inhibitors of acetyltransferase p300 identified by high-throughput screening are potent anticancer agents.
Q37122796Spatiotemporal expression of histone acetyltransferases, p300 and CBP, in developing embryonic hearts
Q37242469TGF-β signaling in endothelial cells, but not neuroepithelial cells, is essential for cerebral vascular development
Q37683304Target gene context influences the transcriptional requirement for the KAT3 family of CBP and p300 histone acetyltransferases.
Q36837326The Rubinstein-Taybi syndrome: modeling mental impairment in the mouse
Q58617586The many lives of KATs - detectors, integrators and modulators of the cellular environment
Q38331056The transcriptional coactivator Cbp regulates self-renewal and differentiation in adult hematopoietic stem cells.
Q28572612The transcriptional coactivator p300 plays a critical role in the hypertrophic and protective pathways induced by phenylephrine in cardiac cells but is specific to the hypertrophic effect of urocortin
Q24309357Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair
Q34037768Transcription coactivators p300 and CBP are necessary for photoreceptor-specific chromatin organization and gene expression
Q35280876Two histone/protein acetyltransferases, CBP and p300, are indispensable for Foxp3+ T-regulatory cell development and function
Q39705049Two transactivation mechanisms cooperate for the bulk of HIF-1-responsive gene expression.
Q39960651VP16-dependent association of chromatin-modifying coactivators and underrepresentation of histones at immediate-early gene promoters during herpes simplex virus infection
Q37260433beta8 integrins are required for vascular morphogenesis in mouse embryos
Q92395381p300 and cAMP response element-binding protein-binding protein in skeletal muscle homeostasis, contractile function, and survival
Q35192595p300-Dependent ATF5 acetylation is essential for Egr-1 gene activation and cell proliferation and survival