scholarly article | Q13442814 |
P2093 | author name string | Paul K Brindle | |
David C Bedford | |||
P2860 | cites work | Role of CBP and SATB-1 in aging, dietary restriction, and insulin-like signaling | Q21092726 |
Intrinsically unstructured proteins and their functions | Q22061731 | ||
TORCs: transducers of regulated CREB activity | Q24297430 | ||
Individual CREB-target genes dictate usage of distinct cAMP-responsive coactivation mechanisms | Q24306838 | ||
Conditional knockout mice reveal distinct functions for the global transcriptional coactivators CBP and p300 in T-cell development | Q24537650 | ||
Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing | Q24612248 | ||
Histone H3K27ac separates active from poised enhancers and predicts developmental state | Q24628758 | ||
Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas | Q24629777 | ||
Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma | Q24630610 | ||
Global transcriptional coactivators CREB-binding protein and p300 are highly essential collectively but not individually in peripheral B cells | Q24685650 | ||
The structural basis of protein acetylation by the p300/CBP transcriptional coactivator | Q27649849 | ||
Lysine acetylation targets protein complexes and co-regulates major cellular functions | Q27860589 | ||
The role of chromatin during transcription | Q27860995 | ||
CBP/p300 in cell growth, transformation, and development | Q28140313 | ||
Extensive brain hemorrhage and embryonic lethality in a mouse null mutant of CREB-binding protein | Q28141517 | ||
CREB-binding protein and p300 in transcriptional regulation | Q28209056 | ||
Structure of histone acetyltransferases | Q28211509 | ||
Histone variant H2A.Z is required for early mammalian development | Q28214088 | ||
Genome-wide mapping of HATs and HDACs reveals distinct functions in active and inactive genes | Q28255974 | ||
CBP histone acetyltransferase activity is a critical component of memory consolidation | Q28267700 | ||
Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300 | Q28270979 | ||
The CREB coactivator TORC2 functions as a calcium- and cAMP-sensitive coincidence detector | Q28285140 | ||
Rubinstein-Taybi syndrome caused by mutations in the transcriptional co-activator CBP | Q28295041 | ||
Distinct roles of GCN5/PCAF-mediated H3K9ac and CBP/p300-mediated H3K18/27ac in nuclear receptor transactivation | Q28299905 | ||
Point mutation in the gene encoding p300 suppresses thrombocytopenia in Mpl-/- mice | Q28593767 | ||
The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism | Q28594811 | ||
Redundant roles for histone H3 N-terminal lysine residues in subtelomeric gene repression in Saccharomyces cerevisiae | Q28768691 | ||
Inactivating mutations of acetyltransferase genes in B-cell lymphoma | Q29031276 | ||
Control of inducible gene expression by signal-dependent transcriptional elongation | Q39285490 | ||
Ablation of CBP in forebrain principal neurons causes modest memory and transcriptional defects and a dramatic reduction of histone acetylation but does not affect cell viability | Q39598834 | ||
Two transactivation mechanisms cooperate for the bulk of HIF-1-responsive gene expression. | Q39705049 | ||
Tumors in Rubinstein-Taybi syndrome | Q40523618 | ||
Defect of histone acetyltransferase activity of the nuclear transcriptional coactivator CBP in Rubinstein-Taybi syndrome | Q40808976 | ||
Regulation of somatostatin gene transcription by cyclic adenosine monophosphate | Q41081338 | ||
Regulation of gene transcription by the histone H2A N-terminal domain | Q41895677 | ||
Double null cells reveal that CBP and p300 are dispensable for p53 targets p21 and Mdm2 but variably required for target genes of other signaling pathways | Q42141606 | ||
A unifying model for the selective regulation of inducible transcription by CpG islands and nucleosome remodeling | Q42252373 | ||
Increased insulin sensitivity despite lipodystrophy in Crebbp heterozygous mice | Q43871563 | ||
Loss of CBP acetyltransferase activity by PHD finger mutations in Rubinstein-Taybi syndrome | Q44302108 | ||
Insulin regulation of hepatic gluconeogenesis through phosphorylation of CREB-binding protein | Q44898066 | ||
Yeast histone H4 N-terminal sequence is required for promoter activation in vivo | Q45268200 | ||
Metformin and insulin meet in a most atypical way. | Q45985592 | ||
Mammalian gene expression program resiliency: the roles of multiple coactivator mechanisms in hypoxia-responsive transcription | Q46853481 | ||
Histone H3 amino terminus is required for telomeric and silent mating locus repression in yeast | Q46976676 | ||
Loss of CBP causes T cell lymphomagenesis in synergy with p27Kip1 insufficiency. | Q48006079 | ||
Yeast histone H2B containing large amino terminus deletions can function in vivo | Q48394496 | ||
Differential role for CBP and p300 CREB-binding domain in motor skill learning. | Q52015251 | ||
Histone modification: cause or cog? | Q52613857 | ||
A transcription-factor-binding surface of coactivator p300 is required for haematopoiesis | Q59098583 | ||
p300/CREB-binding protein interacts with ATR and is required for the DNA replication checkpoint | Q79710648 | ||
Lethality and centrality in protein networks | Q29547267 | ||
A unique chromatin signature uncovers early developmental enhancers in humans | Q29614327 | ||
CREB regulates hepatic gluconeogenesis through the coactivator PGC-1 | Q29615692 | ||
New nomenclature for chromatin-modifying enzymes | Q29616425 | ||
Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma | Q29616862 | ||
Probing nucleosome function: a highly versatile library of synthetic histone H3 and H4 mutants | Q33370815 | ||
Rubinstein-Taybi syndrome. Review of 732 cases and analysis of the typical traits | Q33608737 | ||
Genome-wide views of chromatin structure | Q33611702 | ||
Histone variant macroH2A1 deletion in mice causes female-specific steatosis | Q33803202 | ||
Genomic characterization reveals a simple histone H4 acetylation code. | Q33935027 | ||
Genetic heterogeneity in Rubinstein-Taybi syndrome: mutations in both the CBP and EP300 genes cause disease | Q33942130 | ||
Histone deacetylase inhibitors enhance memory and synaptic plasticity via CREB:CBP-dependent transcriptional activation | Q34077367 | ||
Substitutions in the amino-terminal tail of neurospora histone H3 have varied effects on DNA methylation | Q34126327 | ||
The Aging Stress Response | Q34144973 | ||
Extremely conserved histone H4 N terminus is dispensable for growth but essential for repressing the silent mating loci in yeast | Q34164007 | ||
Chromatin acetylation, memory, and LTP are impaired in CBP+/- mice: a model for the cognitive deficit in Rubinstein-Taybi syndrome and its amelioration. | Q34327866 | ||
Deciphering the roles of the histone H2B N-terminal domain in genome-wide transcription | Q34717455 | ||
CREBBP mutations in relapsed acute lymphoblastic leukaemia | Q34792792 | ||
Epigenetic signatures distinguish multiple classes of enhancers with distinct cellular functions | Q35145499 | ||
Disrupting the CH1 domain structure in the acetyltransferases CBP and p300 results in lean mice with increased metabolic control | Q35185366 | ||
Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP | Q35185929 | ||
A transcription factor-binding domain of the coactivator CBP is essential for long-term memory and the expression of specific target genes | Q35612900 | ||
Drosophila dCBP is involved in establishing the DNA replication checkpoint | Q35641689 | ||
Functional dissection of lysine deacetylases reveals that HDAC1 and p300 regulate AMPK | Q35749976 | ||
p300/CBP and cancer | Q35779695 | ||
Developmental changes in histone macroH2A1-mediated gene regulation | Q35856757 | ||
Chromatin state signatures associated with tissue-specific gene expression and enhancer activity in the embryonic limb | Q36021697 | ||
Abnormal skeletal patterning in embryos lacking a single Cbp allele: a partial similarity with Rubinstein-Taybi syndrome. | Q36584466 | ||
Genetic and genomewide analysis of simultaneous mutations in acetylated and methylated lysine residues in histone H3 in Saccharomyces cerevisiae | Q37102604 | ||
Histone acetyltransferase CBP is vital to demarcate conventional and innate CD8+ T-cell development | Q37247908 | ||
Metformin and insulin suppress hepatic gluconeogenesis through phosphorylation of CREB binding protein | Q37417220 | ||
Target gene context influences the transcriptional requirement for the KAT3 family of CBP and p300 histone acetyltransferases. | Q37683304 | ||
Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladder | Q37730596 | ||
Truncated CBP protein leads to classical Rubinstein-Taybi syndrome phenotypes in mice: implications for a dominant-negative mechanism | Q38328546 | ||
CBP/p300 double null cells reveal effect of coactivator level and diversity on CREB transactivation | Q38340711 | ||
P433 | issue | 4 | |
P921 | main subject | histone acetylation | Q14908264 |
P304 | page(s) | 247-255 | |
P577 | publication date | 2012-04-01 | |
P1433 | published in | Aging | Q2845875 |
P1476 | title | Is histone acetylation the most important physiological function for CBP and p300? | |
P478 | volume | 4 |
Q36094441 | Activation of Nrf2 contributes to the protective effect of Exendin-4 against angiotensin II-induced vascular smooth muscle cell senescence |
Q38185355 | Bromodomains and their pharmacological inhibitors |
Q47369126 | CREBBP and p300 lysine acetyl transferases in the DNA damage response |
Q47746875 | Chemical Control of a CRISPR-Cas9 Acetyltransferase. |
Q92696047 | Combination Targeting of the Bromodomain and Acetyltransferase Active Site of p300/CBP |
Q47251689 | Coordinate regulation of stress signaling and epigenetic events by Acss2 and HIF-2 in cancer cells |
Q33671971 | Crebbp loss cooperates with Bcl2 overexpression to promote lymphoma in mice. |
Q41939319 | DNA methylation pattern in overweight women under an energy-restricted diet supplemented with fish oil. |
Q64082872 | DNA polymerase ι is acetylated in response to S2 alkylating agents |
Q37423469 | Deacetylase-independent function of HDAC3 in transcription and metabolism requires nuclear receptor corepressor |
Q28080288 | Deciphering the Epigenetic Code in Embryonic and Dental Pulp Stem Cells |
Q45353204 | Degradation of CREB-binding protein and modulation of type I interferon induction by the zinc finger motif of the porcine reproductive and respiratory syndrome virus nsp1α subunit |
Q93117000 | Discovery of novel CBP bromodomain inhibitors through TR-FRET-based high-throughput screening |
Q47144438 | Dysregulation of Sirtuin 2 (SIRT2) and histone H3K18 acetylation pathways associates with adverse prostate cancer outcomes |
Q50559758 | Early stress evokes dysregulation of histone modifiers in the medial prefrontal cortex across the life span. |
Q91587544 | Epigenetic Programing of B-Cell Lymphoma by BCL6 and Its Genetic Deregulation |
Q50588458 | Epigenetic Regulation of Memory-Therapeutic Potential for Disorders. |
Q38046794 | Epigenetic alterations in hematopoietic malignancies |
Q49738731 | Epigenetic control of microsomal prostaglandin E synthase-1 by HDAC-mediated recruitment of p300. |
Q28536743 | Genetic interaction between mutations in c-Myb and the KIX domains of CBP and p300 affects multiple blood cell lineages and influences both gene activation and repression |
Q34313018 | Genome-wide and single-cell analyses reveal a context dependent relationship between CBP recruitment and gene expression |
Q43690913 | Genomic landscape of transcriptional and epigenetic dysregulation in early onset polyglutamine disease. |
Q37197807 | Genomic targets, and histone acetylation and gene expression profiling of neural HDAC inhibition |
Q42692796 | Insights into genotype-phenotype correlations from CREBBP point mutation screening in a cohort of 46 Rubinstein-Taybi syndrome patients |
Q48248047 | Integrating genomic alterations in diffuse large B-cell lymphoma identifies new relevant pathways and potential therapeutic targets. |
Q50645739 | Interlocked loops trigger lineage specification and stable fates in the Drosophila nervous system. |
Q35932148 | KRAS and CREBBP mutations: a relapse-linked malicious liaison in childhood high hyperdiploid acute lymphoblastic leukemia |
Q38692163 | Linking functions: an additional role for an intrinsically disordered linker domain in the transcriptional coactivator CBP. |
Q38085375 | Lysine acetyltransferases CBP and p300 as therapeutic targets in cognitive and neurodegenerative disorders. |
Q57298963 | Maternal obesity impairs skeletal development in adult offspring |
Q58581275 | Novel Transcriptional Mechanisms for Regulating Metabolism by Thyroid Hormone |
Q49896590 | P300 Acetyltransferase Mediates Stiffness-Induced Activation of Hepatic Stellate Cells Into Tumor-promoting Myofibroblasts. |
Q36674365 | Phospho-ΔNp63α/microRNA feedback regulation in squamous carcinoma cells upon cisplatin exposure |
Q27021749 | Protein lysine acetylation by p300/CBP |
Q101354739 | Pseudorabies virus glycoprotein gE suppresses interferon-β production via CREB-binding protein degradation |
Q92344797 | Role of Resveratrol and Selenium on Oxidative Stress and Expression of Antioxidant and Anti-Aging Genes in Immortalized Lymphocytes from Alzheimer's Disease Patients |
Q99364934 | Selective inhibition of CBP/p300 HAT by A-485 results in suppression of lipogenesis and hepatic gluconeogenesis |
Q37421692 | Shifting transcriptional machinery is required for long-term memory maintenance and modification in Drosophila mushroom bodies |
Q39113316 | Stepwise acetyltransferase association and histone acetylation at the Myod1 locus during myogenic differentiation. |
Q27685367 | Structure of the p300 catalytic core and implications for chromatin targeting and HAT regulation |
Q52868803 | Sublytic C5b-9 triggers glomerular mesangial cell apoptosis in rat Thy-1 nephritis via Gadd45 activation mediated by Egr-1 and p300-dependent ATF3 acetylation. |
Q40101973 | Suppression of type I interferon production by porcine epidemic diarrhea virus and degradation of CREB-binding protein by nsp1. |
Q28593879 | T-cells null for the MED23 subunit of mediator express decreased levels of KLF2 and inefficiently populate the peripheral lymphoid organs |
Q92641642 | TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile |
Q63383561 | Time-Resolved Analysis Reveals Rapid Dynamics and Broad Scope of the CBP/p300 Acetylome |
Q34037768 | Transcription coactivators p300 and CBP are necessary for photoreceptor-specific chromatin organization and gene expression |
Q57464876 | Transcription factor dimerization activates the p300 acetyltransferase |
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