Ablation of CBP in forebrain principal neurons causes modest memory and transcriptional defects and a dramatic reduction of histone acetylation but does not affect cell viability

scientific article published on February 2011

Ablation of CBP in forebrain principal neurons causes modest memory and transcriptional defects and a dramatic reduction of histone acetylation but does not affect cell viability is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1523/JNEUROSCI.4737-10.2011
P8608Fatcat IDrelease_c7bljudyfjg4nmjlsfszmf2pk4
P932PMC publication ID6623752
P698PubMed publication ID21289174

P50authorLuis M. ValorQ43154749
Matias M PulopulosQ86448930
Angel BarcoQ37387292
P2093author name stringBeat Lutz
Roman Olivares
Maria Jimenez-Minchan
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Sparse, environmentally selective expression of Arc RNA in the upper blade of the rodent fascia dentata by brief spatial experienceQ46514008
Behavioral characteristics of three children with the broad thumb-hallux (Rubinstein-Taybi) syndromeQ46704858
Induction of long-term memory by exposure to novelty requires protein synthesis: evidence for a behavioral taggingQ48107829
Neurotrophin expression in rat hippocampal slices: a stimulus paradigm inducing LTP in CA1 evokes increases in BDNF and NT-3 mRNAsQ48400173
Syndromic features and mild cognitive impairment in mice with genetic reduction on p300 activity: Differential contribution of p300 and CBP to Rubinstein-Taybi syndrome etiologyQ48436070
Regional patterns of c-fos mRNA expression in rat hippocampus following exploration of a novel environment versus performance of a well-learned discrimination.Q48789566
Germline expression of H-Ras(G12V) causes neurological deficits associated to Costello syndromeQ48904488
Rubinstein‐Taybi syndrome medical guidelinesQ52105470
Psychological and speech studies in Rubinstein-Taybi syndromeQ55037142
Correspondence between sites of NGFI-A induction and sites of morphological plasticity following exposure to environmental complexityQ57450720
Membrane depolarization and calcium induce c-fos transcription via phosphorylation of transcription factor CREBQ68454790
Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicityQ95721056
Extensive brain hemorrhage and embryonic lethality in a mouse null mutant of CREB-binding proteinQ28141517
CBP histone acetyltransferase activity is a critical component of memory consolidationQ28267700
Rubinstein-Taybi syndrome caused by mutations in the transcriptional co-activator CBPQ28295041
Subregion- and cell type-restricted gene knockout in mouse brainQ28300369
Epigenetic regulation in psychiatric disordersQ29616296
New nomenclature for chromatin-modifying enzymesQ29616425
Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in DrosophilaQ29616737
p300/CBP proteins: HATs for transcriptional bridges and scaffoldsQ29617981
Control of memory formation through regulated expression of a CaMKII transgeneQ29619261
Recovery of learning and memory is associated with chromatin remodellingQ29619784
Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer's diseaseQ30080016
Quantitative analysis of CBP- and P300-induced histone acetylations in vivo using native chromatin.Q33193939
Histone modification levels are predictive for gene expressionQ33624069
Transgenic mice expressing a truncated form of CREB-binding protein (CBP) exhibit deficits in hippocampal synaptic plasticity and memory storage.Q33736104
Expanded polyglutamine stretches interact with TAFII130, interfering with CREB-dependent transcriptionQ33916580
Genetic heterogeneity in Rubinstein-Taybi syndrome: mutations in both the CBP and EP300 genes cause diseaseQ33942130
Histone deacetylase inhibitors enhance memory and synaptic plasticity via CREB:CBP-dependent transcriptional activationQ34077367
Altered histone acetylation is associated with age-dependent memory impairment in mice.Q34114011
Interaction of expanded polyglutamine stretches with nuclear transcription factors leads to aberrant transcriptional regulation in polyglutamine diseasesQ34158010
Chromatin acetylation, memory, and LTP are impaired in CBP+/- mice: a model for the cognitive deficit in Rubinstein-Taybi syndrome and its amelioration.Q34327866
cAMP response element-binding protein-mediated gene expression increases the intrinsic excitability of CA1 pyramidal neurons.Q34725122
Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's diseaseQ34763178
A transcription factor-binding domain of the coactivator CBP is essential for long-term memory and the expression of specific target genesQ35612900
HATs and HDACs in neurodegeneration: a tale of disconcerted acetylation homeostasis.Q35968237
Epigenetic mechanisms in memory formation.Q36011654
Joining the dots: from chromatin remodeling to neuronal plasticityQ36032226
What's right with my mouse model? New insights into the molecular and cellular basis of cognition from mouse models of Rubinstein-Taybi SyndromeQ36086508
The hippocampal-VTA loop: controlling the entry of information into long-term memoryQ36144286
Chromatin remodeling in neural development and plasticityQ36287001
The Rubinstein-Taybi syndrome: modeling mental impairment in the mouseQ36837326
Decoding the epigenetic language of neuronal plasticityQ37358580
Multiple roles of HDAC inhibition in neurodegenerative conditions.Q37407855
CBP/p300 double null cells reveal effect of coactivator level and diversity on CREB transactivationQ38340711
P4510describes a project that usesImageJQ1659584
P433issue5
P407language of work or nameEnglishQ1860
P921main subjecthistone acetylationQ14908264
P304page(s)1652-1663
P577publication date2011-02-01
P1433published inJournal of NeuroscienceQ1709864
P1476titleAblation of CBP in forebrain principal neurons causes modest memory and transcriptional defects and a dramatic reduction of histone acetylation but does not affect cell viability
P478volume31

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