| scholarly article | Q13442814 |
| P50 | author | Eva Grönroos | Q30419854 |
| P2093 | author name string | Carl-Henrik Heldin | |
| Ulf Hellman | |||
| Johan Ericsson | |||
| P2860 | cites work | Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation | Q24290777 |
| Smurf1 interacts with transforming growth factor-beta type I receptor through Smad7 and induces receptor degradation | Q24291000 | ||
| Negative control of p53 by Sir2alpha promotes cell survival under stress | Q24291828 | ||
| hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase | Q24291829 | ||
| Identification of components of the murine histone deacetylase 6 complex: link between acetylation and ubiquitination signaling pathways | Q24548256 | ||
| Acetylation of histones and transcription-related factors | Q24548503 | ||
| Ligand-dependent degradation of Smad3 by a ubiquitin ligase complex of ROC1 and associated proteins | Q24633428 | ||
| Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain | Q27860534 | ||
| Deacetylation of p53 modulates its effect on cell growth and apoptosis | Q28138967 | ||
| TGF-beta signaling by Smad proteins | Q28139850 | ||
| The Smad4 activation domain (SAD) is a proline-rich, p300-dependent transcriptional activation domain | Q28142707 | ||
| Role of transforming growth factor beta in human disease | Q28143408 | ||
| Regulation of hormone-induced histone hyperacetylation and gene activation via acetylation of an acetylase | Q28144544 | ||
| Regulation of receptor fate by ubiquitination of activated beta 2-adrenergic receptor and beta-arrestin | Q28190513 | ||
| TGF-beta induces assembly of a Smad2-Smurf2 ubiquitin ligase complex that targets SnoN for degradation | Q28199064 | ||
| The MAD-Related Protein Smad7 Associates with the TGFβ Receptor and Functions as an Antagonist of TGFβ Signaling | Q28243202 | ||
| Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling | Q28251743 | ||
| Transforming growth factor beta1 induces nuclear export of inhibitory Smad7 | Q28286474 | ||
| p300/MDM2 complexes participate in MDM2-mediated p53 degradation | Q28288274 | ||
| Histone acetyltransferases | Q29547823 | ||
| Acetylation: a regulatory modification to rival phosphorylation? | Q29614886 | ||
| Transcriptional control by the TGF-beta/Smad signaling system | Q29618985 | ||
| Regulation of gene expression by transcription factor acetylation | Q34058501 | ||
| Signaling of transforming growth factor-beta family members through Smad proteins | Q34098846 | ||
| Suppressor and oncogenic roles of transforming growth factor-beta and its signaling pathways in tumorigenesis | Q34414642 | ||
| p300/CBP-mediated p53 acetylation is commonly induced by p53-activating agents and inhibited by MDM2. | Q34585107 | ||
| The tumor suppressor Smad4/DPC4 and transcriptional adaptor CBP/p300 are coactivators for smad3 in TGF-beta-induced transcriptional activation | Q35205960 | ||
| Site-specific acetylation by p300 or CREB binding protein regulates erythroid Krüppel-like factor transcriptional activity via its interaction with the SWI-SNF complex | Q39458728 | ||
| Multiple C-terminal lysine residues target p53 for ubiquitin-proteasome-mediated degradation | Q39540070 | ||
| Multiple lysine mutations in the C-terminal domain of p53 interfere with MDM2-dependent protein degradation and ubiquitination | Q39540284 | ||
| The transcriptional co-activator P/CAF potentiates TGF-beta/Smad signaling | Q39597497 | ||
| Regulation of E2F1 activity by acetylation | Q40387087 | ||
| TGF-beta-stimulated cooperation of smad proteins with the coactivators CBP/p300 | Q40445183 | ||
| The anaphase-promoting complex mediates TGF-beta signaling by targeting SnoN for destruction | Q40763954 | ||
| Role of p300, a transcriptional coactivator, in signalling of TGF-beta | Q40835770 | ||
| Acetylation of importin-alpha nuclear import factors by CBP/p300. | Q40881413 | ||
| Acetylation of MyoD directed by PCAF is necessary for the execution of the muscle program | Q40908837 | ||
| Acetylation regulates transcription factor activity at multiple levels | Q42799988 | ||
| Regulation of activity of the transcription factor GATA-1 by acetylation | Q42823439 | ||
| Acetylation of HMG I(Y) by CBP turns off IFN beta expression by disrupting the enhanceosome | Q44646118 | ||
| DNA damage-dependent acetylation of p73 dictates the selective activation of apoptotic target genes. | Q50320380 | ||
| Drosophila CBP represses the transcription factor TCF to antagonize Wingless signalling. | Q52566206 | ||
| Physical and functional interaction of SMADs and p300/CBP | Q64381971 | ||
| CREB-binding protein/p300 activates MyoD by acetylation | Q74177706 | ||
| P433 | issue | 3 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | protein ubiquitination | Q3547638 |
| P304 | page(s) | 483-93 | |
| P577 | publication date | 2002-09-01 | |
| P1433 | published in | Molecular Cell | Q3319468 |
| P1476 | title | Control of Smad7 stability by competition between acetylation and ubiquitination | |
| P478 | volume | 10 |
| Q50074816 | A Metabolic Basis for Endothelial-to-Mesenchymal Transition. |
| Q38046131 | A Smurf1 tale: function and regulation of an ubiquitin ligase in multiple cellular networks |
| Q37620700 | A functional role for Smad7 in sustaining colon cancer cell growth and survival. |
| Q37325302 | A new mechanism of RhoA ubiquitination and degradation: roles of SCF(FBXL19) E3 ligase and Erk2. |
| Q35162583 | A superfamily of protein tags: ubiquitin, SUMO and related modifiers |
| Q41969503 | Acetylation and MAPK phosphorylation cooperate to regulate the degradation of active GATA-1 |
| Q37190330 | Acetylation and deacetylation of Cdc25A constitutes a novel mechanism for modulating Cdc25A functions with implications for cancer |
| Q37287396 | Acetylation of Mitochondrial Trifunctional Protein α-Subunit Enhances Its Stability To Promote Fatty Acid Oxidation and Is Decreased in Nonalcoholic Fatty Liver Disease |
| Q38604728 | Acetylation of N-terminus and two internal amino acids is dispensable for degradation of a protein that aberrantly engages the endoplasmic reticulum translocon |
| Q42828663 | Acetylation of Smad2 by the co-activator p300 regulates activin and transforming growth factor beta response |
| Q44530421 | Acetylation of Tat defines a cyclinT1-independent step in HIV transactivation |
| Q33567691 | Acetylation of WRN protein regulates its stability by inhibiting ubiquitination |
| Q34698474 | Acetylation of estrogen receptor alpha by p300 at lysines 266 and 268 enhances the deoxyribonucleic acid binding and transactivation activities of the receptor |
| Q36601373 | Acetylation of p53 augments its site-specific DNA binding both in vitro and in vivo |
| Q33703231 | Acetylation of tau inhibits its degradation and contributes to tauopathy |
| Q24316493 | Acetylation stabilizes ATP-citrate lyase to promote lipid biosynthesis and tumor growth |
| Q24683893 | Acetylation-mediated transcriptional activation of the ETS protein ER81 by p300, P/CAF, and HER2/Neu |
| Q41618085 | Anti-fibrotic effects of valproic acid in experimental peritoneal fibrosis |
| Q34988392 | Association of two variants in SMAD7 with the risk of congenital heart disease in the Han Chinese population |
| Q43848397 | Attenuated TGF-β1 responsiveness of dendritic cells and their precursors in atopic dermatitis |
| Q28577251 | Auto-acetylation stabilizes p300 in cardiac myocytes during acute oxidative stress, promoting STAT3 accumulation and cell survival |
| Q42806222 | Autoacetylation regulates P/CAF nuclear localization. |
| Q39338215 | Autoimmune regulator is acetylated by transcription coactivator CBP/p300. |
| Q61829990 | Biological processes and signal transduction pathways regulated by the protein methyltransferase SETD7 and their significance in cancer |
| Q89638551 | CBP mediated DOT1L acetylation confers DOT1L stability and promotes cancer metastasis |
| Q37661827 | CPLM: a database of protein lysine modifications. |
| Q36653760 | Circadian acetylome reveals regulation of mitochondrial metabolic pathways |
| Q39737054 | Coactivator-dependent acetylation stabilizes members of the SREBP family of transcription factors. |
| Q24537650 | Conditional knockout mice reveal distinct functions for the global transcriptional coactivators CBP and p300 in T-cell development |
| Q28257757 | Crk-associated substrate lymphocyte type regulates transforming growth factor-beta signaling by inhibiting Smad6 and Smad7 |
| Q64082872 | DNA polymerase ι is acetylated in response to S2 alkylating agents |
| Q89075823 | Deficiency of tumor suppressor Merlin facilitates metabolic adaptation by co-operative engagement of SMAD-Hippo signaling in breast cancer |
| Q40437388 | Degradation of the tumor suppressor Smad4 by WW and HECT domain ubiquitin ligases |
| Q90206415 | Discovery of N-(2-Aminophenyl)-4-(bis(2-chloroethyl)amino)Benzamide as a Potent Histone Deacetylase Inhibitor |
| Q58860298 | Discovery of a novel histone deacetylase 8 inhibitor by virtual screening |
| Q37962590 | Elevation of the antifibrotic peptide N-acetyl-seryl-aspartyl-lysyl-proline: a blood pressure-independent beneficial effect of angiotensin I-converting enzyme inhibitors |
| Q41617336 | Epidermal Growth Factor Receptor activation promotes ADA3 acetylation through the AKT-p300 pathway |
| Q24672302 | Essential function of p300 acetyltransferase activity in heart, lung and small intestine formation |
| Q26798369 | Expanding the ubiquitin code through post-translational modification |
| Q37714552 | F-box protein complex FBXL19 regulates TGFβ1-induced E-cadherin down-regulation by mediating Rac3 ubiquitination and degradation |
| Q24297509 | Functional activities and cellular localization of the ezrin, radixin, moesin (ERM) and RING zinc finger domains in MIR |
| Q63383559 | Functions and mechanisms of non-histone protein acetylation |
| Q35681247 | Getting into position: the catalytic mechanisms of protein ubiquitylation |
| Q36956452 | Glutamine Triggers Acetylation-Dependent Degradation of Glutamine Synthetase via the Thalidomide Receptor Cereblon |
| Q47682735 | HDAC1 localizes to the mitochondria of cardiac myocytes and contributes to early cardiac reperfusion injury. |
| Q37372149 | HDAC4 represses vascular endothelial growth factor expression in chondrosarcoma by modulating RUNX2 activity |
| Q54959760 | HPV16-E6 Oncoprotein Activates TGF-β and Wnt/β-Catenin Pathways in the Epithelium-Mesenchymal Transition of Cataracts in a Transgenic Mouse Model. |
| Q88011201 | Histone acetyltransferase CBP promotes function of SCF FBXL19 ubiquitin E3 ligase by acetylation and stabilization of its F-box protein subunit |
| Q37792465 | Histone acetyltransferase mediated regulation of FOXP3 acetylation and Treg function |
| Q38572921 | Histone and Non-Histone Targets of Dietary Deacetylase Inhibitors |
| Q36645808 | Histone deacetylase inhibitors (HDACIs): multitargeted anticancer agents |
| Q29615649 | Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer |
| Q35042270 | Histone deacetylase inhibitors with enhanced enzymatic inhibition effects and potent in vitro and in vivo antitumor activities |
| Q44673407 | Inhibition of ubiquitin/proteasome-dependent proteolysis in Saccharomyces cerevisiae by a Gly-Ala repeat |
| Q35105653 | Inhibitory SMADs: potential regulators of ovarian function |
| Q38598015 | Integrating multiple signals into cell decisions by networks of protein modification cycles |
| Q38976614 | KATapulting toward Pluripotency and Cancer |
| Q26824916 | Key role for ubiquitin protein modification in TGFβ signal transduction |
| Q28385337 | LPS impairs oxygen utilization in epithelia by triggering degradation of the mitochondrial enzyme Alcat1 |
| Q51129815 | Lipopolysaccharide Activates Toll-Like Receptor 4 and Prevents Cardiac Fibroblast-to-Myofibroblast Differentiation. |
| Q47837957 | Lipopolysaccharide modulates p300 and Sirt1 to promote PRMT1 stability via an SCFFbxl17-recognized acetyldegron. |
| Q36513464 | Lithium inhibits Smad3/4 transactivation via increased CREB activity induced by enhanced PKA and AKT signaling |
| Q48098684 | Lysine Acetylation Goes Global: From Epigenetics to Metabolism and Therapeutics. |
| Q24306325 | MSAP is a novel MIR-interacting protein that enhances neurite outgrowth and increases myosin regulatory light chain |
| Q38193043 | MYC degradation |
| Q30002367 | Mass Spectrometric Analysis of Lysine Ubiquitylation Reveals Promiscuity at Site Level |
| Q27015931 | Mechanisms of Histone Deacetylase Inhibitor-Regulated Gene Expression in Cancer Cells |
| Q27860785 | Mechanisms of TGF-beta signaling from cell membrane to the nucleus |
| Q36135254 | Mechanistic insights into the regulation of metabolic enzymes by acetylation |
| Q28510844 | Methylation of Smad6 by protein arginine N-methyltransferase 1 |
| Q36593428 | Mortality factor 4 like 1 protein mediates epithelial cell death in a mouse model of pneumonia |
| Q27008887 | N-acetyl-seryl-aspartyl-lysyl-proline: a valuable endogenous anti-fibrotic peptide for combating kidney fibrosis in diabetes |
| Q28298423 | NUP98 dysregulation in myeloid leukemogenesis |
| Q34315255 | Next-generation proteomics: towards an integrative view of proteome dynamics. |
| Q35739676 | Nonhistone protein acetylation as cancer therapy targets |
| Q42175822 | Nuclear Smad7 Overexpressed in Mesenchymal Cells Acts as a Transcriptional Corepressor by Interacting with HDAC-1 and E2F to Regulate Cell Cycle |
| Q36826106 | Nuclear receptor coactivators: structural and functional biochemistry |
| Q37437183 | Osterix acetylation at K307 and K312 enhances its transcriptional activity and is required for osteoblast differentiation. |
| Q40601394 | Overexpression of Smurf1 negatively regulates mouse embryonic lung branching morphogenesis by specifically reducing Smad1 and Smad5 proteins |
| Q40272529 | PJA2 ubiquitinates the HIV-1 Tat protein with atypical chain linkages to activate viral transcription |
| Q34155238 | Pleiotropic Effects of p300-mediated Acetylation on p68 and p72 RNA Helicase |
| Q38012228 | Post-translational regulation of TGF-β receptor and Smad signaling. |
| Q39026435 | Posttranslational Regulation of Smads |
| Q91452021 | Proteasome-dependent degradation of Smad7 is critical for lung cancer metastasis |
| Q38476064 | RANKL induces NFATc1 acetylation and stability via histone acetyltransferases during osteoclast differentiation |
| Q33886284 | Rapid temporal control of Foxp3 protein degradation by sirtuin-1. |
| Q58789901 | Reciprocal Regulation Between Smad7 and Sirt1 in the Gut |
| Q36756039 | Reciprocal regulation of RORγt acetylation and function by p300 and HDAC1. |
| Q35044538 | Regulating the regulators: lysine modifications make their mark |
| Q37333694 | Regulating the stability of TGFbeta receptors and Smads |
| Q24324035 | Regulation of MEF2 by histone deacetylase 4- and SIRT1 deacetylase-mediated lysine modifications |
| Q35652597 | Regulation of Smad activities |
| Q37437251 | Regulation of TGF-beta signaling by Smad7. |
| Q37779572 | Regulation of TGF-beta signalling by protein phosphatases |
| Q39029996 | Regulation of TGF-β Family Signaling by Inhibitory Smads. |
| Q26827667 | Regulation of TGF-β signal transduction by mono- and deubiquitylation of Smads |
| Q35200617 | Regulation of distinct biological activities of the NF-kappaB transcription factor complex by acetylation |
| Q35691559 | Regulation of the TGFbeta signalling pathway by ubiquitin-mediated degradation |
| Q38020840 | Regulation of the transforming growth factor β pathway by reversible ubiquitylation |
| Q49885765 | Restoration of mutant hERG stability by inhibition of HDAC6. |
| Q47302478 | Reversible Notch1 acetylation tunes proliferative signalling in cardiomyocytes |
| Q90408538 | Rhein, a novel Histone Deacetylase (HDAC) inhibitor with antifibrotic potency in human myocardial fibrosis |
| Q38598542 | Role of Smad signaling in kidney disease |
| Q38060113 | Role of Smad7 in inflammatory bowel diseases |
| Q37885217 | Role of Smads in TGFβ signaling |
| Q34383040 | Roles and targets of class I and IIa histone deacetylases in cardiac hypertrophy |
| Q40419434 | Roles for lysine residues of the MH2 domain of Smad3 in transforming growth factor-beta signaling |
| Q35234999 | S-nitrosylation and S-palmitoylation reciprocally regulate synaptic targeting of PSD-95 |
| Q34628087 | SCF E3 ligase F-box protein complex SCF(FBXL19) regulates cell migration by mediating Rac1 ubiquitination and degradation |
| Q37037723 | SET9-Mediated Regulation of TGF-β Signaling Links Protein Methylation to Pulmonary Fibrosis |
| Q28589415 | SIRT1 inhibits transforming growth factor beta-induced apoptosis in glomerular mesangial cells via Smad7 deacetylation |
| Q47137087 | Sirt1 interaction with active Smad2 modulates transforming growth factor-β regulated transcription. |
| Q28208250 | Smad-dependent and Smad-independent pathways in TGF-beta family signalling |
| Q79968429 | Smad3 is acetylated by p300/CBP to regulate its transactivation activity |
| Q40438629 | Smad7 abrogates transforming growth factor-beta1-mediated growth inhibition in COLO-357 cells through functional inactivation of the retinoblastoma protein |
| Q53031706 | Smad7 enhances ATM activity by facilitating the interaction between ATM and Mre11-Rad50-Nbs1 complex in DNA double-strand break repair. |
| Q40351576 | Smad7 induces G0/G1 cell cycle arrest in mesenchymal cells by inhibiting the expression of G1 cyclins |
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