Valproic acid suppresses collagen by selective regulation of Smads in conjunctival fibrosis

scientific article published on 27 October 2015

Valproic acid suppresses collagen by selective regulation of Smads in conjunctival fibrosis is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1007/S00109-015-1358-Z
P932PMC publication ID4803820
P698PubMed publication ID26507880
P5875ResearchGate publication ID283306634

P2093author name stringLi-Fong Seet
Tina T Wong
Branko Stefanovic
Li Zhen Toh
Stephanie W L Chu
Sharon N Finger
P2860cites workTransforming growth factor beta -inducible independent binding of SMAD to the Smad7 promoterQ22254141
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Valproic acid induces cutaneous wound healing in vivo and enhances keratinocyte motilityQ28484912
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SPARC deficiency results in improved surgical survival in a novel mouse model of glaucoma filtration surgeryQ33535934
Transforming growth factor-beta1 up-regulation of human alpha(1)(I) collagen is mediated by Sp1 and Smad2 transacting factorsQ33805741
SMAD and p38 MAPK signaling pathways independently regulate alpha1(I) collagen gene expression in unstimulated and transforming growth factor-beta-stimulated hepatic stellate cells.Q50781080
Novel insight into the inflammatory and cellular responses following experimental glaucoma surgery: a roadmap for inhibiting fibrosis.Q51013571
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Expression and regulation of intracellular SMAD signaling in scleroderma skin fibroblastsQ73628355
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Homeobox gene Prx1 is expressed in activated hepatic stellate cells and transactivates collagen alpha1(I) promoterQ80763912
Antitumor histone deacetylase inhibitors suppress cutaneous radiation syndrome: Implications for increasing therapeutic gain in cancer radiotherapyQ95781492
Basic pharmacology of valproate: a review after 35 years of clinical use for the treatment of epilepsyQ34150830
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Valproic acid activates the PI3K/Akt/mTOR pathway in muscle and ameliorates pathology in a mouse model of Duchenne muscular dystrophyQ37150816
In vitro analyses of the anti-fibrotic effect of SPARC silencing in human Tenon's fibroblasts: comparisons with mitomycin C.Q37295174
Dynamic interplay between the collagen scaffold and tumor evolutionQ37786073
Surgical management of glaucoma: a reviewQ37984667
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Myofibroblast differentiation by transforming growth factor-beta1 is dependent on cell adhesion and integrin signaling via focal adhesion kinase.Q42435832
Comparison of trichostatin A and valproic acid treatment regimens in a mouse model of kidney fibrosisQ42711032
Chronic administration of valproic acid inhibits activation of mouse hepatic stellate cells in vitro and in vivoQ43231143
Histone deacetylase modulates the proinflammatory and -fibrotic changes in tubulointerstitial injuryQ43244113
Smad6 inhibits non-canonical TGF-β1 signalling by recruiting the deubiquitinase A20 to TRAF6.Q43492573
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P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue3
P304page(s)321-334
P577publication date2015-10-27
P1433published inJournal of Molecular MedicineQ6295593
P1476titleValproic acid suppresses collagen by selective regulation of Smads in conjunctival fibrosis
P478volume94