| review article | Q7318358 |
| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/J.CYTOGFR.2005.09.008 |
| P698 | PubMed publication ID | 16290023 |
| P50 | author | Anita Roberts | Q4765627 |
| Christina H Stuelten | Q54877821 | ||
| P2093 | author name string | Fang Tian | |
| Kathleen C Flanders | |||
| Akira Ooshima | |||
| Shizuya Saika | |||
| Stacey DaCosta Byfield | |||
| P433 | issue | 1-2 | |
| P304 | page(s) | 19-27 | |
| P577 | publication date | 2005-11-11 | |
| P1433 | published in | Cytokine and Growth Factor Reviews | Q15763303 |
| P1476 | title | Smad3 is key to TGF-beta-mediated epithelial-to-mesenchymal transition, fibrosis, tumor suppression and metastasis | |
| P478 | volume | 17 |
| Q91230219 | A TGF-β associated genetic score to define prognosis and platinum sensitivity in advanced epithelial ovarian cancer |
| Q34686306 | Accelerating repaired basement membrane after bevacizumab treatment on alkali-burned mouse cornea |
| Q39664271 | Activin A induces SLC5A8 expression through the Smad3 signaling pathway in human colon cancer RKO cells |
| Q43786434 | Acute and chronic effects of dietary sodium restriction on renal tubulointerstitial fibrosis in cisplatin-treated rats |
| Q36983438 | An anti-transforming growth factor beta antibody suppresses metastasis via cooperative effects on multiple cell compartments. |
| Q33894802 | Anchoring hepatic gene expression with development of fibrosis and neoplasia in a toxicant-induced fish model of liver injury |
| Q61854900 | Angiotensin II activates the Smad pathway during epithelial mesenchymal transdifferentiation |
| Q38314657 | Antifibrotic effect of synthetic Smad/Sp1 chimeric decoy oligodeoxynucleotide through the regulation of epithelial mesenchymal transition in unilateral ureteral obstruction model of mice |
| Q36163970 | Aqueous Extract of Gumiganghwal-tang, a Traditional Herbal Medicine, Reduces Pulmonary Fibrosis by Transforming Growth Factor-β1/Smad Signaling Pathway in Murine Model of Chronic Asthma |
| Q24685123 | Axin and GSK3- control Smad3 protein stability and modulate TGF- signaling |
| Q34629931 | Beta-elemene blocks epithelial-mesenchymal transition in human breast cancer cell line MCF-7 through Smad3-mediated down-regulation of nuclear transcription factors |
| Q37970379 | Biochemical role of the collagen-rich tumour microenvironment in pancreatic cancer progression |
| Q41645535 | Blockade of Orai1 Store-Operated Calcium Entry Protects against Renal Fibrosis. |
| Q39402781 | Bone morphogenetic protein-7 inhibits proximal tubular epithelial cell Smad3 signaling via increased SnoN expression. |
| Q55643144 | Cellular and Molecular Mediators of Bone Metastatic Lesions. |
| Q35677074 | Combinatorial activation of FAK and AKT by transforming growth factor-beta1 confers an anoikis-resistant phenotype to myofibroblasts |
| Q38899586 | Context dependent non canonical WNT signaling mediates activation of fibroblasts by transforming growth factor-β. |
| Q37402327 | Critical role of interleukin-11 in isoflurane-mediated protection against ischemic acute kidney injury in mice |
| Q38798056 | Curcumin inhibits metastasis in human papillary thyroid carcinoma BCPAP cells via down-regulation of the TGF-β/Smad2/3 signaling pathway |
| Q26825789 | DEAR1, a novel tumor suppressor that regulates cell polarity and epithelial plasticity |
| Q38958008 | Definition of smad3 phosphorylation events that affect malignant and metastatic behaviors in breast cancer cells |
| Q38012499 | Developing histone deacetylase inhibitors in the therapeutic armamentarium of pancreatic adenocarcinoma. |
| Q46933819 | Differentiation plasticity regulated by TGF-beta family proteins in development and disease |
| Q37934555 | Diverse roles of TGF-β/Smads in renal fibrosis and inflammation |
| Q42364411 | Effect of echinacoside on kidney fibrosis by inhibition of TGF-β1/Smads signaling pathway in the db/db mice model of diabetic nephropathy |
| Q43693945 | Effect of mycophenolic acid on cyclosporin A-induced fibronectin expression in rat mesangial cells |
| Q54365521 | Effect of nilotinib on bleomycin-induced acute lung injury and pulmonary fibrosis in mice. |
| Q38904870 | Elf5 inhibits TGF-β-driven epithelial-mesenchymal transition in prostate cancer by repressing SMAD3 activation |
| Q28393597 | Emodin suppresses silica-induced lung fibrosis by promoting Sirt1 signaling via direct contact |
| Q53292601 | Endothelial Mesenchymal Transition: A Therapeutic Target in Retrocorneal Membrane |
| Q96292689 | Enhancer Reprogramming within Pre-existing Topologically Associated Domains Promotes TGF-β-Induced EMT and Cancer Metastasis |
| Q38453116 | Epithelial Mesenchymal Transition: a double-edged sword |
| Q33996286 | Epithelial origin of myofibroblasts during fibrosis in the lung |
| Q39636372 | Epithelial-mesenchymal transition of the retinal pigment epithelium causes choriocapillaris atrophy |
| Q44898872 | Evidence for a role of epithelial mesenchymal transition during pathogenesis of fistulae in Crohn's disease |
| Q37302849 | Evolution history of duplicated smad3 genes in teleost: insights from Japanese flounder, Paralichthys olivaceus |
| Q38730872 | Evolving paradigm of treatment for autoimmune hepatitis |
| Q90115346 | Exosomes and pancreatic diseases: status, challenges, and hopes |
| Q39602802 | Expression, purification, and functional characterization of recombinant PTD-SARA. |
| Q37170606 | FGF-regulated BMP signaling is required for eyelid closure and to specify conjunctival epithelial cell fate |
| Q33643763 | Fate-determining mechanisms in epithelial-myofibroblast transition: major inhibitory role for Smad3 |
| Q98164841 | GNS561 acts as a potent anti-fibrotic and pro-fibrolytic agent in liver fibrosis through TGF-β1 inhibition |
| Q39262943 | Ganglioside GM3 participates in the TGF-β1-induced epithelial-mesenchymal transition of human lens epithelial cells |
| Q35159549 | Genetic deficiency of Smad3 protects against murine ischemic acute kidney injury |
| Q30498922 | Genetic variation in the TGF-β signaling pathway and colon and rectal cancer risk |
| Q58801550 | Geniposide Alleviates Isoproterenol-Induced Cardiac Fibrosis Partially via SIRT1 Activation and |
| Q34011439 | Grape seed pro-anthocyanidins ameliorates radiation-induced lung injury |
| Q41833631 | Gremlin activates the Smad pathway linked to epithelial mesenchymal transdifferentiation in cultured tubular epithelial cells. |
| Q47676484 | Gremlin and renal diseases: ready to jump the fence to clinical utility? |
| Q37676697 | Growth factors as active participants in carcinogenesis: a perspective |
| Q34584292 | HDAC6 deacetylase activity is required for hypoxia-induced invadopodia formation and cell invasion |
| Q33631382 | HRD1-Mediated IGF-1R Ubiquitination Contributes to Renal Protection of Resveratrol in db/db Mice |
| Q33976494 | HSP72 attenuates renal tubular cell apoptosis and interstitial fibrosis in obstructive nephropathy. |
| Q33916249 | High throughput determination of TGFβ1/SMAD3 targets in A549 lung epithelial cells |
| Q35632155 | Histone acetyltransferase inhibitor C646 reverses epithelial to mesenchymal transition of human peritoneal mesothelial cells via blocking TGF-β1/Smad3 signaling pathway in vitro |
| Q35274680 | IGFBP-rP1 suppresses epithelial-mesenchymal transition and metastasis in colorectal cancer |
| Q37054538 | IL4 and IL-17A provide a Th2/Th17-polarized inflammatory milieu in favor of TGF-β1 to induce bronchial epithelial-mesenchymal transition (EMT). |
| Q92689602 | Identification of De Novo Enhancers Activated by TGFβ to Drive Expression of CDKN2A and B in HeLa Cells |
| Q52328455 | Identification of Epithelial-Mesenchymal Transition-related Target Genes Induced by the Mutation of Smad3 Linker Phosphorylation. |
| Q38754843 | Identifying inhibitors of epithelial-mesenchymal transition by connectivity map-based systems approach |
| Q46027836 | Increased expression of connective tissue growth factor and transforming growth factor-beta-1 in atrial myocardium of patients with chronic atrial fibrillation. |
| Q43230127 | Inhibitory effect of blocking TGF-beta/Smad signal on injury-induced fibrosis of corneal endothelium. |
| Q30422043 | Interactions between β-catenin and transforming growth factor-β signaling pathways mediate epithelial-mesenchymal transition and are dependent on the transcriptional co-activator cAMP-response element-binding protein (CREB)-binding protein (CBP). |
| Q39855944 | Interleukin-1 beta regulates proximal tubular cell transforming growth factor beta-1 signalling |
| Q35990325 | Kaempferol Suppresses Transforming Growth Factor-β1-Induced Epithelial-to-Mesenchymal Transition and Migration of A549 Lung Cancer Cells by Inhibiting Akt1-Mediated Phosphorylation of Smad3 at Threonine-179. |
| Q37119917 | Kindlin-2 mediates activation of TGF-β/Smad signaling and renal fibrosis |
| Q24313188 | Ligand-dependent ubiquitination of Smad3 is regulated by casein kinase 1 gamma 2, an inhibitor of TGF-beta signaling |
| Q33405240 | Liver cancer-derived hepatitis C virus core proteins shift TGF-beta responses from tumor suppression to epithelial-mesenchymal transition |
| Q36017059 | Losartan Attenuates Myocardial Endothelial-To-Mesenchymal Transition in Spontaneous Hypertensive Rats via Inhibiting TGF-β/Smad Signaling |
| Q30301313 | Loss of BRMS1 promotes a mesenchymal phenotype through NF-κB-dependent regulation of Twist1. |
| Q40185259 | Loss of osteopontin perturbs the epithelial-mesenchymal transition in an injured mouse lens epithelium |
| Q34962663 | Low-dose paclitaxel ameliorates pulmonary fibrosis by suppressing TGF-β1/Smad3 pathway via miR-140 upregulation |
| Q64114397 | MDM2 promotes epithelial-mesenchymal transition through activation of Smad2/3 signaling pathway in lung adenocarcinoma |
| Q92366574 | Mechanism of epithelial‑mesenchymal transition inhibited by miR‑203 in non‑small cell lung cancer |
| Q54299380 | Mechanisms navigating the TGF-β pathway in prostate cancer. |
| Q55497904 | Molecular Mechanisms and Treatment of Radiation-Induced Lung Fibrosis. |
| Q34142102 | Molecular mechanisms and treatment of radiation-induced lung fibrosis |
| Q41024386 | Naringenin prevents experimental liver fibrosis by blocking TGFβ-Smad3 and JNK-Smad3 pathways. |
| Q38895458 | Nature and Implications of Oxidative and Nitrosative Stresses in Autoimmune Hepatitis |
| Q91814309 | Negative Control of Cell Migration by Rac1b in Highly Metastatic Pancreatic Cancer Cells Is Mediated by Sequential Induction of Nonactivated Smad3 and Biglycan |
| Q46970674 | Neoplastic and nonneoplastic liver lesions induced by dimethylnitrosamine in Japanese medaka fish |
| Q37888661 | New insights into the pathogenesis and treatment of idiopathic pulmonary fibrosis |
| Q28578937 | Noncanonical TGF-beta pathways, mTORC1 and Abl, in renal interstitial fibrogenesis |
| Q89930454 | Nontoxic concentration of ochratoxin A decreases the dosage of cyclosporine A to induce chronic nephropathy model via autophagy mediated by toll-like receptor 4 |
| Q33475969 | Novel sequential ChIP and simplified basic ChIP protocols for promoter co-occupancy and target gene identification in human embryonic stem cells |
| Q34695847 | Pancreatic cancer cells respond to type I collagen by inducing snail expression to promote membrane type 1 matrix metalloproteinase-dependent collagen invasion |
| Q61810971 | Phosphorylation status at Smad3 linker region modulates transforming growth factor-β-induced epithelial-mesenchymal transition and cancer progression |
| Q99579045 | Polydatin prevents bleomycin-induced pulmonary fibrosis by inhibiting the TGF-β/Smad/ERK signaling pathway |
| Q34560071 | Preventing or reducing late side effects of radiation therapy: radiobiology meets molecular pathology |
| Q30420643 | Pulmonary sequelae in a patient recovered from swine flu. |
| Q36909242 | Qinggan Huoxue Recipe suppresses epithelial-to-mesenchymal transition in alcoholic liver fibrosis through TGF-β1/Smad signaling pathway |
| Q34149752 | Radiation therapy causes loss of dermal lymphatic vessels and interferes with lymphatic function by TGF-beta1-mediated tissue fibrosis |
| Q36992934 | Regulation of the anaphase-promoting complex-separase cascade by transforming growth factor-beta modulates mitotic progression in bone marrow stromal cells |
| Q41621899 | Relationships between SMAD3 expression and preoperative fluoropyrimidine-based chemoradiotherapy response in locally advanced rectal cancer patients |
| Q36475553 | Relevance of the stroma and epithelial-mesenchymal transition (EMT) for the rheumatic diseases |
| Q36777948 | Requirement of HDAC6 for transforming growth factor-beta1-induced epithelial-mesenchymal transition. |
| Q61807550 | Reversion of in vivo fibrogenesis by novel chromone scaffolds |
| Q38924183 | Role of TGF-β1/p38 MAPK pathway in hepatitis B virus-induced tubular epithelial-myofibroblast transdifferentiation |
| Q34088326 | Role of alphavbeta6 integrin in acute biliary fibrosis |
| Q36677493 | Role of transforming growth factor-beta in cancer progression |
| Q55400547 | Runt-Related Transcription Factor 1 (RUNX1) Promotes TGF-β-Induced Renal Tubular Epithelial-to-Mesenchymal Transition (EMT) and Renal Fibrosis through the PI3K Subunit p110δ. |
| Q26740442 | SIRT1 and Kidney Function |
| Q39641433 | SKIP is required for TGF-β1-induced epithelial mesenchymal transition and migration in transformed keratinocytes. |
| Q50430901 | SOX4: Joining the Master Regulators of Epithelial-to-Mesenchymal Transition? |
| Q28259664 | Severe acute respiratory syndrome-associated coronavirus nucleocapsid protein interacts with Smad3 and modulates transforming growth factor-beta signaling |
| Q64275526 | Shen Shuai IIRecipe attenuates renal injury and fibrosis in chronic kidney disease by regulating NLRP3 inflammasome and Sirt1/Smad3 deacetylation pathway |
| Q39427622 | Side population cells in human gallbladder cancer cell line GBC-SD regulated by TGF-β-induced epithelial-mesenchymal transition |
| Q30812886 | Single-Molecule Imaging Reveals the Activation Dynamics of Intracellular Protein Smad3 on Cell Membrane |
| Q53077318 | Sirt1 activation ameliorates renal fibrosis by inhibiting the TGF-β/Smad3 pathway. |
| Q35478946 | Smad phosphoisoform signaling specificity: the right place at the right time |
| Q35649316 | Smad phosphoisoform signals in acute and chronic liver injury: similarities and differences between epithelial and mesenchymal cells |
| Q34455322 | Smad2 protects against TGF-beta/Smad3-mediated renal fibrosis. |
| Q85887123 | Smad2 protects against TGF-β1/Smad3-mediated collagen synthesis in human hepatic stellate cells during hepatic fibrosis |
| Q39454247 | Smad3 regulates E-cadherin via miRNA-200 pathway |
| Q37078617 | Specific activation of mitogen-activated protein kinase by transforming growth factor-beta receptors in lipid rafts is required for epithelial cell plasticity |
| Q41369308 | Statins inhibit angiotensin II/Smad pathway and related vascular fibrosis, by a TGF-β-independent process. |
| Q37799828 | Stem cells in gastrointestinal cancers: a matter of choice in cell fate determination |
| Q33980575 | Suppression of injury-induced epithelial-mesenchymal transition in a mouse lens epithelium lacking tenascin-C |
| Q40641564 | Suppressive effect of microRNA-29b on hepatic stellate cell activation and its crosstalk with TGF-β1/Smad3. |
| Q37113958 | TGF-beta mediated epithelial-mesenchymal transition in autosomal dominant polycystic kidney disease |
| Q34124223 | TGF-beta receptor deletion in the renal collecting system exacerbates fibrosis. |
| Q35826016 | TGF-β synergizes with defects in the Hippo pathway to stimulate human malignant mesothelioma growth |
| Q44537770 | TGF-β-Induced Endothelial-Mesenchymal Transition in Fibrotic Diseases. |
| Q35142712 | TGF-β/Smad3 signaling promotes renal fibrosis by inhibiting miR-29 |
| Q39592007 | TGF-β1-induced EMT of non-transformed prostate hyperplasia cells is characterized by early induction of SNAI2/Slug. |
| Q37195207 | TGFbeta promotes Wnt expression during cataract development |
| Q28275410 | TGFβ signalling in context |
| Q38925875 | TNF-related weak inducer of apoptosis (TWEAK) regulates junctional proteins in tubular epithelial cells via canonical NF-κB pathway and ERK activation |
| Q38902371 | Targeting Hepatic Fibrosis in Autoimmune Hepatitis. |
| Q33823577 | Targeting signal transduction pathways to eliminate chemotherapeutic drug resistance and cancer stem cells. |
| Q33933880 | Targeting the Transforming Growth Factor-beta pathway inhibits human basal-like breast cancer metastasis. |
| Q58795274 | The Chinese Medicine, Jiedu Recipe, Inhibits the Epithelial Mesenchymal Transition of Hepatocellular Carcinoma via the Regulation of Smad2/3 Dependent and Independent Pathways |
| Q33850210 | The Chinese medicine, Jianpi Huayu Decoction, inhibits the epithelial mesenchymal transition via the regulation of the Smad3/Smad7 cascade |
| Q35788620 | The Disintegrin and Metalloprotease ADAM12 Is Associated with TGF-β-Induced Epithelial to Mesenchymal Transition. |
| Q30436035 | The RhoA activator GEF-H1/Lfc is a transforming growth factor-beta target gene and effector that regulates alpha-smooth muscle actin expression and cell migration |
| Q24652992 | The basics of epithelial-mesenchymal transition |
| Q34662804 | The four-herb Chinese medicine ANBP enhances wound healing and inhibits scar formation via bidirectional regulation of transformation growth factor pathway |
| Q64102536 | The functional switch of TGF-β signaling in breast cancer |
| Q35961854 | The transcription factor scleraxis is a critical regulator of cardiac fibroblast phenotype |
| Q37786166 | Transforming Growth Factor β Signal Transduction: A Potential Target for Maintenance/Restoration of Transparency of the Cornea |
| Q28083526 | Transforming Growth Factor-Beta and Oxidative Stress Interplay: Implications in Tumorigenesis and Cancer Progression |
| Q35895390 | Transforming growth factor beta signaling in adult cardiovascular diseases and repair. |
| Q38132176 | Transforming growth factor-Beta and urokinase-type plasminogen activator: dangerous partners in tumorigenesis-implications in skin cancer |
| Q34232534 | Transforming growth factor-beta and fibrosis |
| Q34162353 | Transforming growth factor-{beta}1 induces Smad3-dependent {beta}1 integrin gene expression in epithelial-to-mesenchymal transition during chronic tubulointerstitial fibrosis |
| Q39443785 | Transforming growth factor-β, matrix metalloproteinases, and urokinase-type plasminogen activator interaction in the cancer epithelial to mesenchymal transition |
| Q35106053 | Transition of mesothelial cell to fibroblast in peritoneal dialysis: EMT, stem cell or bystander? |
| Q36717858 | Valproic acid suppresses collagen by selective regulation of Smads in conjunctival fibrosis |
| Q64230111 | and its monomers alleviate liver fibrosis both in mice and LX2 cells by blocking TβR1-Smad2/3 and TNF-α-NF-κB pathways |
| Q42066518 | c-Jun N-terminal kinase 1 promotes transforming growth factor-β1-induced epithelial-to-mesenchymal transition via control of linker phosphorylation and transcriptional activity of Smad3. |
| Q98939659 | lncRNA lnc-TSI Inhibits Metastasis of Clear Cell Renal Cell Carcinoma by Suppressing TGF-β-Induced Epithelial-Mesenchymal Transition |
| Q41848371 | miR-200b is involved in intestinal fibrosis of Crohn's disease |
| Q55022670 | miR-24 and miR-122 Negatively Regulate the Transforming Growth Factor-β/Smad Signaling Pathway in Skeletal Muscle Fibrosis. |
| Q91613348 | β-Catenin/Smad3 Interaction Regulates Transforming Growth Factor-β-Induced Epithelial to Mesenchymal Transition in the Lens |
| Q39454012 | β-catenin and Smad3 regulate the activity and stability of myocardin-related transcription factor during epithelial-myofibroblast transition |
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