scholarly article | Q13442814 |
P50 | author | Rosemary J Akhurst | Q91233041 |
P2093 | author name string | Rik Derynck | |
P2860 | cites work | Myostatin mutation associated with gross muscle hypertrophy in a child | Q24297666 |
A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva | Q24321505 | ||
Loss of Smad3-mediated negative regulation of Runx2 activity leads to an alteration in cell fate determination | Q24534967 | ||
Myostatin negatively regulates satellite cell activation and self-renewal | Q24675245 | ||
Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis | Q28131703 | ||
Smad transcription factors | Q28284775 | ||
Bone morphogenetic proteins | Q28300236 | ||
Transforming growth factor-beta regulation of immune responses | Q28303115 | ||
Defective ALK5 signaling in the neural crest leads to increased postmigratory neural crest cell apoptosis and severe outflow tract defects | Q28506220 | ||
The tumor suppressor gene Smad4/Dpc4 is required for gastrulation and later for anterior development of the mouse embryo | Q28512702 | ||
Specificity and versatility in tgf-beta signaling through Smads | Q29616324 | ||
Evidence that fibroblasts derive from epithelium during tissue fibrosis | Q29616581 | ||
High interstitial fluid pressure - an obstacle in cancer therapy | Q29619719 | ||
Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix | Q29619797 | ||
Endoglin and Alk5 regulate epithelial-mesenchymal transformation during cardiac valve formation. | Q30480194 | ||
The role of Smad signaling in hematopoiesis | Q33222328 | ||
Human pulmonary valve progenitor cells exhibit endothelial/mesenchymal plasticity in response to vascular endothelial growth factor-A and transforming growth factor-beta2. | Q33606662 | ||
TGF-beta and the Smad signaling pathway support transcriptomic reprogramming during epithelial-mesenchymal cell transition | Q33734595 | ||
Muscle regeneration in the prolonged absence of myostatin | Q33830785 | ||
Non-Smad TGF-beta signals | Q34443708 | ||
Myostatin: biology and clinical relevance | Q34547599 | ||
Wnt and TGF-beta signaling are required for the induction of an in vitro model of primitive streak formation using embryonic stem cells | Q34578176 | ||
Integration of TGF-beta and Ras/MAPK signaling through p53 phosphorylation. | Q34603719 | ||
Osteogenic differentiation of mouse adipose-derived adult stromal cells requires retinoic acid and bone morphogenetic protein receptor type IB signaling | Q35033676 | ||
Induction of epithelial-mesenchymal transition in alveolar epithelial cells by transforming growth factor-beta1: potential role in idiopathic pulmonary fibrosis | Q35087744 | ||
Revisiting the role of retinoid signaling in skeletal development | Q35211792 | ||
Improvement of cancer-targeting therapy, using nanocarriers for intractable solid tumors by inhibition of TGF-beta signaling. | Q35641963 | ||
Dissection of key events in tubular epithelial to myofibroblast transition and its implications in renal interstitial fibrosis | Q35746891 | ||
Epithelial to mesenchymal transition in human breast cancer can provide a nonmalignant stroma | Q35748940 | ||
Histopathology of cutaneous squamous cell carcinoma and its variants | Q35750666 | ||
BMP2-mediated alteration in the developmental pathway of fetal mouse brain cells from neurogenesis to astrocytogenesis | Q35900138 | ||
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Spindle cell metaplasia in follicular adenoma of the thyroid gland: case report and review of the literature. | Q35934001 | ||
Myostatin and its implications on animal breeding: a review | Q36019955 | ||
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Bone morphogenetic protein-2 converts the differentiation pathway of C2C12 myoblasts into the osteoblast lineage | Q36235105 | ||
Smad3 is key to TGF-beta-mediated epithelial-to-mesenchymal transition, fibrosis, tumor suppression and metastasis. | Q36313734 | ||
Bone morphogenetic protein and retinoic acid signaling cooperate to induce osteoblast differentiation of preadipocytes | Q36324476 | ||
Concise review: bone morphogenetic protein pleiotropism in neural stem cells and their derivatives--alternative pathways, convergent signals | Q36594573 | ||
Transforming growth factor-beta 3 is required for secondary palate fusion | Q37373842 | ||
Ras and TGF[beta] cooperatively regulate epithelial cell plasticity and metastasis: dissection of Ras signaling pathways | Q40757186 | ||
Co-expression of tenascin-C and vimentin in human breast cancer cells indicates phenotypic transdifferentiation during tumour progression: correlation with histopathological parameters, hormone receptors, and oncoproteins | Q40827270 | ||
Overexpression of an osteogenic morphogen in fibrodysplasia ossificans progressiva | Q41174010 | ||
Deletion of Smad2 in mouse liver reveals novel functions in hepatocyte growth and differentiation | Q42160419 | ||
Activin receptor-like kinase 2 and Smad6 regulate epithelial-mesenchymal transformation during cardiac valve formation | Q46377767 | ||
Adipose-derived adult stromal cells heal critical-size mouse calvarial defects | Q46567472 | ||
Autologous stem cells (adipose) and fibrin glue used to treat widespread traumatic calvarial defects: case report. | Q51578610 | ||
Metastasis is driven by sequential elevation of H-ras and Smad2 levels. | Q54297451 | ||
Inhibition of TGF-beta modulates macrophages and vessel maturation in parallel to a lowering of interstitial fluid pressure in experimental carcinoma | Q81402283 | ||
P433 | issue | 9 | |
P304 | page(s) | 1000-1004 | |
P577 | publication date | 2007-09-01 | |
P1433 | published in | Nature Cell Biology | Q1574111 |
P1476 | title | Differentiation plasticity regulated by TGF-beta family proteins in development and disease | |
P478 | volume | 9 |
Q47824296 | A mutation update on the LDS associated genes TGFB2/3 and SMAD2/3. |
Q33733916 | ASK-ing EMT not to spread cancer |
Q47847040 | Aberrant Smad3 phosphoisoforms in cyst-lining epithelial cells in the cpk mouse, a model of autosomal recessive polycystic kidney disease |
Q33568654 | Absence of c-Jun NH2-terminal kinase 1 protects against house dust mite-induced pulmonary remodeling but not airway hyperresponsiveness and inflammation |
Q92755581 | Activation of TGF-β Canonical and Noncanonical Signaling in Bovine Lactoferrin-Induced Osteogenic Activity of C3H10T1/2 Mesenchymal Stem Cells |
Q92671088 | Alendronate disturbs femoral growth due to changes during immunolocalization of transforming growth factor-β1 and bone morphogenetic protein-2 in epiphyseal plate |
Q55260314 | An NFκB-dependent mechanism of tumor cell plasticity and lateral transmission of aggressive features. |
Q34977307 | An autocrine TGF-beta/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition |
Q37273999 | An autocrine loop between TGF-β1 and the transcription factor brachyury controls the transition of human carcinoma cells into a mesenchymal phenotype |
Q36545124 | An epigenetic auto-feedback loop regulates TGF-β type II receptor expression and function in NSCLC. |
Q39044432 | Androgen receptor inducing bladder cancer progression by promoting an epithelial-mesenchymal transition |
Q43276050 | Anti-fibrotic effect of thalidomide through inhibiting TGF-beta-induced ERK1/2 pathways in bleomycin-induced lung fibrosis in mice |
Q47725453 | Apoptotic and Nonapoptotic Activities of Pterostilbene against Cancer |
Q24339143 | C18 ORF1, a novel negative regulator of transforming growth factor-β signaling |
Q33966545 | CLIC4 and Schnurri-2: a dynamic duo in TGF-beta signaling with broader implications in cellular homeostasis and disease |
Q37885165 | Cancer cells in epithelial-to-mesenchymal transition and tumor-propagating-cancer stem cells: distinct, overlapping or same populations |
Q39648681 | Carcinoembryonic antigen interacts with TGF-{beta} receptor and inhibits TGF-{beta} signaling in colorectal cancers. |
Q92348371 | Cathepsin L-mediated resistance of paclitaxel and cisplatin is mediated by distinct regulatory mechanisms |
Q34284046 | Co-expression analysis of fetal weight-related genes in ovine skeletal muscle during mid and late fetal development stages |
Q27693607 | Complexities of TGF-β targeted cancer therapy |
Q42147850 | Computational modelling of Smad-mediated negative feedback and crosstalk in the TGF-β superfamily network |
Q30496670 | Conversion of mouse epiblast stem cells to an earlier pluripotency state by small molecules. |
Q28543093 | Curcumin suppresses crosstalk between colon cancer stem cells and stromal fibroblasts in the tumor microenvironment: potential role of EMT |
Q27302374 | Cyclic stretch of embryonic cardiomyocytes increases proliferation, growth, and expression while repressing Tgf-β signaling |
Q39481263 | Cysteine-rich protein 1 is regulated by transforming growth factor-β1 and expressed in lung fibrosis. |
Q38626767 | Cytoskeletal signaling in TGFβ-induced epithelial-mesenchymal transition |
Q46328407 | D-mannose induces regulatory T cells and suppresses immunopathology. |
Q27851466 | DPC4 gene status of the primary carcinoma correlates with patterns of failure in patients with pancreatic cancer. |
Q84847835 | De novo lung cancer diagnosed 32 months after liver transplantation: report of a case |
Q37735806 | Decitabine reverses TGF-β1-induced epithelial-mesenchymal transition in non-small-cell lung cancer by regulating miR-200/ZEB axis |
Q36723199 | Dermal adipocytes and hair cycling: is spatial heterogeneity a characteristic feature of the dermal adipose tissue depot? |
Q37998023 | Differential Regulation of TGF-β/Smad Signaling in Hepatic Stellate Cells between Acute and Chronic Liver Injuries |
Q52617207 | Differential regulation of the two RhoA-specific GEF isoforms Net1/Net1A by TGF-β and miR-24: role in epithelial-to-mesenchymal transition. |
Q39441340 | Direct signaling between platelets and cancer cells induces an epithelial-mesenchymal-like transition and promotes metastasis |
Q34979224 | ERBB Receptor Activation Is Required for Profibrotic Responses to Transforming Growth Factor β |
Q38930830 | EW-7197 inhibits hepatic, renal, and pulmonary fibrosis by blocking TGF-β/Smad and ROS signaling |
Q38936472 | Effect of collagen vascular disease-associated interstitial lung disease on the outcomes of lung cancer surgery |
Q38039303 | Epigenetic control of epithelial-to-mesenchymal transition and cancer metastasis |
Q33798864 | Epithelial-mesenchymal transition in prostate cancer: an overview. |
Q47394908 | Exploring molecular mechanism of bone-forming capacity of Eurycoma longifolia: Evidence of enhanced expression of bone-related biomarkers. |
Q45866814 | Expression of vimentin and survivin in clear cell renal cell carcinoma and correlation with p53. |
Q34029378 | Fibrodysplasia ossificans progressiva: a blueprint for metamorphosis |
Q35813719 | Fibrodysplasia ossificans progressiva: a human genetic disorder of extraskeletal bone formation, or--how does one tissue become another? |
Q45051195 | Fibronectin fibrils regulate TGF-β1-induced Epithelial-Mesenchymal Transition. |
Q38725648 | Gene therapy strategies to improve strength and quality of flexor tendon healing |
Q37398195 | Generation of mice with a conditional allele for transforming growth factor beta 1 gene |
Q47121253 | Growth differentiation factor 15 mediates epithelial mesenchymal transition and invasion of breast cancers through IGF-1R-FoxM1 signaling |
Q90352370 | H3K18ac Primes Mesendodermal Differentiation upon Nodal Signaling |
Q33916249 | High throughput determination of TGFβ1/SMAD3 targets in A549 lung epithelial cells |
Q80507318 | Human mesenchymal stem cell transformation is associated with a mesenchymal-epithelial transition |
Q30436925 | Identification of progenitor cells that contribute to heterotopic skeletogenesis |
Q90672348 | Immune Cell Induced Migration of Osteoprogenitor Cells Is Mediated by TGF-β Dependent Upregulation of NOX4 and Activation of Focal Adhesion Kinase |
Q39382972 | Induced transgene expression for the treatment of solid tumors by hematopoietic stem cell-based gene therapy. |
Q36732552 | Inflammation and Hras signaling control epithelial-mesenchymal transition during skin tumor progression. |
Q36552107 | Inherited human diseases of heterotopic bone formation |
Q34790572 | Insights from a rare genetic disorder of extra-skeletal bone formation, fibrodysplasia ossificans progressiva (FOP) |
Q36790379 | Integration of multiple signaling pathways determines differences in the osteogenic potential and tissue regeneration of neural crest-derived and mesoderm-derived calvarial bones |
Q36483438 | Integration of transforming growth factor beta and RAS signaling silences a RAB5 guanine nucleotide exchange factor and enhances growth factor-directed cell migration |
Q92784010 | Integrin-Mediated TGFβ Activation Modulates the Tumour Microenvironment |
Q34236843 | Involvement of the serum response factor coactivator megakaryoblastic leukemia (MKL) in the activin-regulated dendritic complexity of rat cortical neurons |
Q35039000 | Itch E3 ubiquitin ligase positively regulates TGF-β signaling to EMT via Smad7 ubiquitination |
Q26776349 | Krüppel-like factor 17, a novel tumor suppressor: its low expression is involved in cancer metastasis |
Q38266863 | Linker phosphorylation of Smad3 promotes fibro-carcinogenesis in chronic viral hepatitis of hepatocellular carcinoma |
Q92860048 | LncRNA XIST enhanced TGF-β2 expression by targeting miR-141-3p to promote pancreatic cancer cells invasion |
Q47426600 | Long non-coding RNA SNHG1 regulates NOB1 expression by sponging miR-326 and promotes tumorigenesis in osteosarcoma |
Q37697174 | Long noncoding RNA BX357664 regulates cell proliferation and epithelial-to-mesenchymal transition via inhibition of TGF-β1/p38/HSP27 signaling in renal cell carcinoma |
Q54298655 | MAPK inhibitors differently modulate TGF-β/Smad signaling in HepG2 cells. |
Q38732277 | Mathematical models of cell phenotype regulation and reprogramming: Make cancer cells sensitive again! |
Q37364008 | Matrix Producing Cells in Chronic Kidney Disease: Origin, Regulation, and Activation. |
Q92366574 | Mechanism of epithelial‑mesenchymal transition inhibited by miR‑203 in non‑small cell lung cancer |
Q38336989 | Mechanisms of tumor-induced T cell immune suppression and therapeutics to counter those effects |
Q37143914 | Memory encoded throughout our bodies: molecular and cellular basis of tissue regeneration |
Q26769611 | Metabolic derivatives of alcohol and the molecular culprits of fibro-hepatocarcinogenesis: Allies or enemies? |
Q58733981 | Metformin inhibits ovarian cancer growth and migration in vitro and in vivo by enhancing cisplatin cytotoxicity |
Q64994489 | MiR-940 inhibits TGF-β-induced epithelial-mesenchymal transition and cell invasion by targeting Snail in non-small cell lung cancer. |
Q36772647 | Microfluidic artificial "vessels" for dynamic mechanical stimulation of mesenchymal stem cells |
Q51567189 | Molecular mechanisms of transforming growth factor-β signaling and disease: The 59th Fujihara International Seminar, 2010. |
Q34365632 | Molecular pathways and targets in prostate cancer |
Q33687048 | Mutant p53 gain-of-function in cancer |
Q41143462 | Negative feedback loop between ZBTB7A and TGF-β in breast cancer |
Q89809785 | Network and pathway-based analyses of genes associated with osteoporosis |
Q38086746 | Neurotrophic molecules in the treatment of neurodegenerative disease with focus on the retina: status and perspectives |
Q29620040 | Non-Smad pathways in TGF-beta signaling |
Q37044600 | Noncanonical TGF-β signaling during mammary tumorigenesis |
Q26799919 | Noncoding RNAs, Emerging Regulators of Skeletal Muscle Development and Diseases |
Q57269883 | Nuclear receptor NR4A1 promotes breast cancer invasion and metastasis by activating TGF-β signalling |
Q36629996 | Oestrogen signalling in white adipose progenitor cells inhibits differentiation into brown adipose and smooth muscle cells |
Q30539142 | Olfactomedin-1 activity identifies a cell invasion checkpoint during epithelial-mesenchymal transition in the chick embryonic heart |
Q34687503 | Outgrowth of drug-resistant carcinomas expressing markers of tumor aggression after long-term TβRI/II kinase inhibition with LY2109761. |
Q39924024 | PLP2, a potent deubiquitinase from murine hepatitis virus, strongly inhibits cellular type I interferon production |
Q39029043 | Pharmacological and immunological targeting of tumor mesenchymalization |
Q35384921 | Pituitary tumor transforming gene induces epithelial to mesenchymal transition by regulation of Twist, Snail, Slug, and E-cadherin |
Q38764247 | Plasticity underlies tumor progression: role of Nodal signaling |
Q99579045 | Polydatin prevents bleomycin-induced pulmonary fibrosis by inhibiting the TGF-β/Smad/ERK signaling pathway |
Q50173304 | Preclinical assessment of galunisertib (LY2157299 monohydrate), a first-in-class transforming growth factor-β receptor type I inhibitor. |
Q42705478 | Profibrotic up-regulation of glucose transporter 1 by TGF-β involves activation of MEK and mammalian target of rapamycin complex 2 pathways. |
Q21091051 | Prominent bone loss mediated by RANKL and IL-17 produced by CD4+ T cells in TallyHo/JngJ mice |
Q34140633 | Protein kinase D1 maintains the epithelial phenotype by inducing a DNA-bound, inactive SNAI1 transcriptional repressor complex |
Q58770630 | Reawakening of dormant estrogen-dependent human breast cancer cells by bone marrow stroma secretory senescence |
Q37437251 | Regulation of TGF-beta signaling by Smad7. |
Q40534248 | Regulation of a TGF-β1-CD147 self-sustaining network in the differentiation plasticity of hepatocellular carcinoma cells |
Q33898042 | Requirement of a dynein light chain in TGFbeta/Smad3 signaling |
Q37003924 | Retromer maintains basolateral distribution of the type II TGF-β receptor via the recycling endosome |
Q37591417 | Role of TGF-β in breast cancer bone metastases. |
Q28081170 | Role of TGFβ in regulation of the tumor microenvironment and drug delivery (review) |
Q36208494 | Role of altered signal transduction in heterotopic ossification and fibrodysplasia ossificans progressiva |
Q33694557 | Role of androgens and the androgen receptor in epithelial-mesenchymal transition and invasion of prostate cancer cells |
Q36521628 | Role of stem/progenitor cells in reparative disorders |
Q37339711 | Roles of TGFbeta in metastasis |
Q34542397 | SOX4 mediates TGF-β-induced expression of mesenchymal markers during mammary cell epithelial to mesenchymal transition |
Q33684614 | Signaling via Alk5 controls the ontogeny of lung Clara cells. |
Q35649316 | Smad phosphoisoform signals in acute and chronic liver injury: similarities and differences between epithelial and mesenchymal cells |
Q42507999 | Smad2 decelerates re-epithelialization during gingival wound healing |
Q53391030 | Smad3 and its phosphoisoforms are prognostic predictors of hepatocellular carcinoma after curative hepatectomy. |
Q43492573 | Smad6 inhibits non-canonical TGF-β1 signalling by recruiting the deubiquitinase A20 to TRAF6. |
Q35868376 | Smad7 Modulates Epidermal Growth Factor Receptor Turnover through Sequestration of c-Cbl |
Q34503198 | Somatic cell plasticity and Niemann-Pick type C2 protein: fibroblast activation |
Q37078617 | Specific activation of mitogen-activated protein kinase by transforming growth factor-beta receptors in lipid rafts is required for epithelial cell plasticity |
Q58991601 | Studies on thePinctada fucataBMP-2 Gene: Structural Similarity and Functional Conservation of Its Osteogenic Potential within the Animal Kingdom |
Q42724556 | TGF-β Conveys Undesirable Side Effects of Androgen Depletion |
Q38747679 | TGF-β Effects on Prostate Cancer Cell Migration and Invasion Require FosB. |
Q39155183 | TGF-β Family Signaling in Connective Tissue and Skeletal Diseases |
Q39155158 | TGF-β Family Signaling in Tumor Suppression and Cancer Progression. |
Q26995720 | TGF-β and BMP signaling in osteoblast differentiation and bone formation |
Q28274611 | TGF-β family signaling in stem cells |
Q37900199 | TGF-β in the Bone Microenvironment: Role in Breast Cancer Metastases |
Q38633657 | TGF-β induces growth suppression in multiple myeloma MM.1S cells via E2F1. |
Q36297071 | TGF-β-Induced Transcription Sustains Amoeboid Melanoma Migration and Dissemination. |
Q42059520 | TGF-β1 alters microRNA profile in human gastric cancer cells |
Q57138555 | TGF-β1 programmed myeloid-derived suppressor cells (MDSC) acquire immune-stimulating and tumor killing activity capable of rejecting established tumors in combination with radiotherapy |
Q35608186 | TGF-β1 signaling and Krüppel-like factor 10 regulate bone marrow-derived proangiogenic cell differentiation, function, and neovascularization |
Q47915386 | TGF-β1 targets Smad, p38 MAPK, and PI3K/Akt signaling pathways to induce PFKFB3 gene expression and glycolysis in glioblastoma cells |
Q51065073 | TGF-β1-induced synthesis of collagen fibers in skeletal muscle-derived stem cells. |
Q28288866 | TGFbeta in Cancer |
Q28083107 | TGFβ Signaling in Tumor Initiation, Epithelial-to-Mesenchymal Transition, and Metastasis |
Q28275410 | TGFβ signalling in context |
Q33827621 | TGFβ1 enhances MAD1 expression and stimulates promoter-bound Pol II phosphorylation: basic functions of C/EBP, SP and SMAD3 transcription factors |
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Q57142667 | Targeting TGF-beta in prostate cancer: therapeutic possibilities during tumor progression |
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Q27012443 | Targeting TGF-β signaling in cancer |
Q35583991 | Targeting the TGF-beta1 pathway to prevent normal tissue injury after cancer therapy |
Q36462348 | Targeting the TGFβ signalling pathway in disease |
Q27021750 | Targeting the Transforming Growth Factor-β Signaling in Cancer Therapy |
Q33517772 | Targeting the transforming growth factor-beta signaling pathway in human cancer |
Q38168211 | Tgf-Beta family signaling in embryonic stem cells. |
Q36985643 | The Dual Role of TGFβ in Human Cancer: From Tumor Suppression to Cancer Metastasis |
Q34020080 | The FOP metamorphogene encodes a novel type I receptor that dysregulates BMP signaling |
Q28596581 | The Hippo kinases LATS1 and 2 control human breast cell fate via crosstalk with ERα |
Q39076794 | The TGF-β/Smad4 Signaling Pathway in Pancreatic Carcinogenesis and Its Clinical Significance. |
Q39140421 | The TGFβ-induced phosphorylation and activation of p38 mitogen-activated protein kinase is mediated by MAP3K4 and MAP3K10 but not TAK1. |
Q44159142 | The atypical chemokine receptor CCX-CKR regulates metastasis of mammary carcinoma via an effect on EMT. |
Q50082534 | The concomitant apoptosis and EMT underlie the fundamental functions of TGF-β. |
Q37403100 | The fibrodysplasia ossificans progressiva R206H ACVR1 mutation activates BMP-independent chondrogenesis and zebrafish embryo ventralization |
Q64044987 | The fibrogenic chemokine CCL18 is associated with disease severity in Erdheim-Chester disease |
Q38647611 | The footprint of TGF-β in airway remodeling of the mustard lung |
Q36149873 | The importance of foetal movement for co-ordinated cartilage and bone development in utero : clinical consequences and potential for therapy. |
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Q38129383 | The role of TGF-β in bone metastasis: novel therapeutic perspectives |
Q33514874 | The transcriptional cofactor nab2 is induced by tgf-Beta and suppresses fibroblast activation: physiological roles and impaired expression in scleroderma |
Q36799312 | The ubiquitin ligase Smurf2 suppresses TGFβ-induced epithelial-mesenchymal transition in a sumoylation-regulated manner |
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Q28505676 | Transforming growth factor Beta2 is required for valve remodeling during heart development |
Q35895390 | Transforming growth factor beta signaling in adult cardiovascular diseases and repair. |
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Q38095920 | Vascular smooth muscle cell differentiation-2010. |
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