Tip60 histone acetyltransferase acts as a negative regulator of Notch1 signaling by means of acetylation

scientific article (publication date: September 2007)

Tip60 histone acetyltransferase acts as a negative regulator of Notch1 signaling by means of acetylation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/MCB.01515-06
P8608Fatcat IDrelease_dtsgzlptjre4nf3cqvxmzw34v4
P3181OpenCitations bibliographic resource ID4789825
P932PMC publication ID2099611
P698PubMed publication ID17636029
P5875ResearchGate publication ID6202495

P2093author name stringJin-Young Kim
Eun-Jung Ann
Hee-Sae Park
Ji-Hye Park
Jung-Soon Mo
Mi-Sun Seo
Mi-Yeon Kim
Sun-Yee Kim
P2860cites workCIR, a corepressor linking the DNA binding factor CBF1 to the histone deacetylase complexQ22008610
The Bcl-3 oncoprotein acts as a bridging factor between NF-kappaB/Rel and nuclear co-regulatorsQ22009958
Rel/NF-kappaB can trigger the Notch signaling pathway by inducing the expression of Jagged1, a ligand for Notch receptorsQ22010043
Recognition and ubiquitination of Notch by Itch, a hect-type E3 ubiquitin ligaseQ24273416
Involvement of the TIP60 histone acetylase complex in DNA repair and apoptosisQ24290159
HOXD3 regulates expression of JAGGED1, a ligand for Notch receptorsQ24306592
Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humansQ24308701
Tip60 and p400 are both required for UV-induced apoptosis but play antagonistic roles in cell cycle progressionQ24315714
The mammalian YL1 protein is a shared subunit of the TRRAP/TIP60 histone acetyltransferase and SRCAP complexesQ24337907
Human SRCAP and Drosophila melanogaster DOM are homologs that function in the notch signaling pathwayQ24529979
The acetyltransferase 60 kDa trans-acting regulatory protein of HIV type 1-interacting protein (Tip60) interacts with the translocation E26 transforming-specific leukaemia gene (TEL) and functions as a transcriptional co-repressorQ24530158
MYC recruits the TIP60 histone acetyltransferase complex to chromatinQ24535721
Tip60 is targeted to proteasome-mediated degradation by Mdm2 and accumulates after UV irradiationQ24536285
A CADASIL-mutated Notch 3 receptor exhibits impaired intracellular trafficking and maturation but normal ligand-induced signaling.Q24544042
SEL-10 is an inhibitor of notch signaling that targets notch for ubiquitin-mediated protein degradationQ24548288
A histone deacetylase corepressor complex regulates the Notch signal transduction pathwayQ24598533
High-efficiency transformation of mammalian cells by plasmid DNAQ27860469
Notch signaling: cell fate control and signal integration in developmentQ27861061
Control of the histone-acetyltransferase activity of Tip60 by the HIV-1 transactivator protein, TatQ28138797
Tip60 inhibits activation of CREB protein by protein kinase AQ28138881
Notch signaling: from the outside inQ28139768
Phosphorylation by glycogen synthase kinase-3 beta down-regulates Notch activity, a link for Notch and Wnt pathwaysQ28177635
Tip60 is a nuclear hormone receptor coactivatorQ28199349
A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60Q28205099
Tip60 is a co-repressor for STAT3Q28205252
The Notch intracellular domain is ubiquitinated and negatively regulated by the mammalian Sel-10 homologQ28207494
Glycogen synthase kinase-3beta modulates notch signaling and stabilityQ28215000
Exchange of N-CoR corepressor and Tip60 coactivator complexes links gene expression by NF-kappaB and beta-amyloid precursor proteinQ28216526
Tip60 and histone deacetylase 1 regulate androgen receptor activity through changes to the acetylation status of the receptorQ28216750
Cellular functions of TIP60Q28240003
Notch signaling: control of cell communication and cell fateQ28245948
Novel substrate specificity of the histone acetyltransferase activity of HIV-1-Tat interactive protein Tip60Q28255673
Physical interaction between a novel domain of the receptor Notch and the transcription factor RBP-J kappa/Su(H)Q28286560
Hes1 and Hes5 as notch effectors in mammalian neuronal differentiation.Q28505355
Reactivation of Delta-Notch signaling after injury: complementary expression patterns of ligand and receptor in dental pulpQ28573069
Interaction of the MAGUK family member Acvrinp1 and the cytoplasmic domain of the Notch ligand Delta1Q28585547
Notch signalling is required for cyclic expression of the hairy-like gene HES1 in the presomitic mesodermQ28594325
Pattern formation during C. elegans vulval inductionQ32117066
Regulation of T cell fate by NotchQ33652483
Control of histone modificationsQ33813434
The many HATs of transcription coactivatorsQ33818804
MyoD stimulates delta-1 transcription and triggers notch signaling in the Xenopus gastrulaQ33890698
Notch signal transduction: a real rip and moreQ33964063
Mammalian histone acetyltransferases and their complexesQ34082910
Regulating histone acetyltransferases and deacetylasesQ34250532
Glycosylation regulates Notch signalling.Q34271410
Hsp72 functions as a natural inhibitory protein of c-Jun N-terminal kinaseQ34271504
Transcriptional regulation of a metastasis suppressor gene by Tip60 and beta-catenin complexesQ34411407
Pattern formation in the zebrafish retinaQ34458295
Nipped-A, the Tra1/TRRAP subunit of the Drosophila SAGA and Tip60 complexes, has multiple roles in Notch signaling during wing developmentQ34519966
Multiple levels of Notch signal regulation (review).Q34624335
Molecular control of cortical dendrite developmentQ34674837
Keeping a good pathway down: transcriptional repression of Notch pathway target genes by CSL proteinsQ34838458
A {gamma}-secretase-independent mechanism of signal transduction by the amyloid precursor proteinQ35021238
Altered Notch ligand expression in human liver disease: further evidence for a role of the Notch signaling pathway in hepatic neovascularization and biliary ductular defectsQ35748038
Choosing a cell fate: a view from the Notch locusQ36471891
Delta-induced Notch signaling mediated by RBP-J inhibits MyoD expression and myogenesisQ38327383
Notch1 intracellular domain suppresses APP intracellular domain-Tip60-Fe65 complex mediated signaling through physical interactionQ40157442
Parathyroid hormone stimulates expression of the Notch ligand Jagged1 in osteoblastic cells.Q40285802
HIV-1 Tat targets Tip60 to impair the apoptotic cell response to genotoxic stressesQ40400941
Acetylation by Tip60 is required for selective histone variant exchange at DNA lesionsQ40495236
Role of the histone acetyl transferase Tip60 in the p53 pathwayQ40525578
Developmental signaling. Vertebrate ligands for Notch.Q40935500
Recent advances in understanding signal transduction pathways in worms and fliesQ40944012
The ins and outs of notch signalingQ41552048
Chromatin remodeling and the control of gene expressionQ41629038
Notch on the cutting edgeQ41684100
The LIN-12/Notch signaling pathway and its regulationQ41689370
Inhibition of histone deacetylase activity by trichostatin A modulates gene expression during mouse embryogenesis without apparent toxicityQ43540209
UDP-sugar transporter implicated in glycosylation and processing of NotchQ43726763
Tip60 is a co-activator specific for class I nuclear hormone receptorsQ43760059
Notch signalling acts in postmitotic avian myogenic cells to control MyoD activationQ44023836
Histone deacetylase 1 regulates retinal neurogenesis in zebrafish by suppressing Wnt and Notch signaling pathways.Q46535329
LIN-12/Notch trafficking and regulation of DSL ligand activity during vulval induction in Caenorhabditis elegansQ46763724
Histone deacetylase 1 is required to repress Notch target gene expression during zebrafish neurogenesis and to maintain the production of motoneurones in response to hedgehog signallingQ47073240
A subset of notch functions during Drosophila eye development require Su(H) and the E(spl) gene complex.Q47875745
The intracellular domain of mouse Notch: a constitutively activated repressor of myogenesis directed at the basic helix-loop-helix region of MyoD.Q51131644
Functional relationships between Notch, Su(H) and the bHLH genes of the E(spl) complex: the E(spl) genes mediate only a subset of Notch activities during imaginal development.Q52200197
The Notch signalling pathway is required for Enhancer of split bHLH protein expression during neurogenesis in the Drosophila embryo.Q52539992
Genetic interactions among vestigial, hairy, and Notch suggest a role of vestigial in the differentiation of epidermal and neural cells of the wing and halter of Drosophila melanogaster.Q52551481
Notch signaling: direct or what?Q77210653
P433issue18
P407language of work or nameEnglishQ1860
P921main subjectcell biologyQ7141
P304page(s)6506-19
P577publication date2007-09-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleTip60 histone acetyltransferase acts as a negative regulator of Notch1 signaling by means of acetylation
P478volume27

Reverse relations

cites work (P2860)
Q82696715Acetylation controls Notch3 stability and function in T-cell leukemia
Q37612583Acetylation promotes TyrRS nuclear translocation to prevent oxidative damage
Q34628594Acetylation-dependent regulation of endothelial Notch signalling by the SIRT1 deacetylase
Q33566900Ataxin-1 regulates epithelial-mesenchymal transition of cervical cancer cells
Q30494474Co-localization of the amyloid precursor protein and Notch intracellular domains in nuclear transcription factories
Q35763040Dual regulation of notch1 signaling pathway by adaptor protein fe65
Q38482269Inhibition of Notch1 signaling by Runx2 during osteoblast differentiation.
Q47263859Interaction of the epigenetic integrator UHRF1 with the MYST domain of TIP60 inside the cell
Q33675489Involvement of TIP60 acetyltransferase in intracellular Salmonella replication
Q53469568JIP1 binding to RBP-Jk mediates cross-talk between the Notch1 and JIP1-JNK signaling pathway.
Q39687663MDR1 mediated chemoresistance: BMI1 and TIP60 in action
Q37816250MYST-family histone acetyltransferases: beyond chromatin.
Q37589507NUMB inhibition of NOTCH signalling as a therapeutic target in prostate cancer
Q37785199Notch Targets and Their Regulation
Q36799234Notch1 modulates oxidative stress induced cell death through suppression of apoptosis signal-regulating kinase 1.
Q36724322Schizosaccharomyces pombe histone acetyltransferase Mst1 (KAT5) is an essential protein required for damage response and chromosome segregation
Q37520579Sensitizing mucoepidermoid carcinomas to chemotherapy by targeted disruption of cancer stem cells
Q38619007Tat-interactive Protein-60KDA (TIP60) Regulates the Tumorigenesis of Lung Cancer In Vitro
Q53227690The intracellular domain of Jagged-1 interacts with Notch1 intracellular domain and promotes its degradation through Fbw7 E3 ligase.
Q43233345Widespread regulation of gene expression in the Drosophila genome by the histone acetyltransferase dTip60.
Q36347670Wnt5a controls Notch1 signaling through CaMKII-mediated degradation of the SMRT corepressor protein

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