Molecular cloning of a levocabastine-sensitive neurotensin binding site

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Molecular cloning of a levocabastine-sensitive neurotensin binding site is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/0014-5793(96)00397-3
P698PubMed publication ID8647296
P5875ResearchGate publication ID14553860

P2093author name stringD Caput
G Le Fur
P Chalon
P Ferrara
M Kaghad
B Delpech
J Bonnin
M Guillemot
N Vita
P2860cites workDistribution and immunochemical character of neurotensin-like material in representative vertebrates and invertebrates: apparent conservation of the COOH-terminal region during evolutionQ48969481
Cloning and expression of a complementary DNA encoding a high affinity human neurotensin receptorQ24314254
Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform ExtractionQ25938986
Neurotensin receptors: binding properties, transduction pathways, and structureQ28285248
Evidence for a displaceable non-specific [3H]neurotensin binding site in rat brainQ28287754
Identification of a polymorphism in the human neurotensin receptor geneQ36754789
Neurotensin receptor expression in the rat forebrain and midbrain: a combined analysis by in situ hybridization and receptor autoradiographyQ38310093
The neurotensin receptor: is there more than one subtype?Q41097997
Characterization of the effect of SR48692 on inositol monophosphate, cyclic GMP and cyclic AMP responses linked to neurotensin receptor activation in neuronal and non-neuronal cellsQ41300669
The rat neurotensin receptor expressed in Chinese hamster ovary cells mediates the release of inositol phosphatesQ41597301
Structure and functional expression of the cloned rat neurotensin receptorQ41733457
Neurotensin stimulates inositol trisphosphate-mediated calcium mobilization but not protein kinase C activation in HT29 cells. Involvement of a G-proteinQ41758169
The nonpeptide neurotensin antagonist, SR 48692, used as a tool to reveal putative neurotensin receptor subtypesQ41899918
Phospholipase C activation by neurotensin and neuromedin N in Chinese hamster ovary cells expressing the rat neurotensin receptorQ41960985
Regulation of cyclic GMP levels by neurotensin in neuroblastoma clone N1E115.Q42507132
SR 48692, a non-peptide neurotensin receptor antagonist differentially affects neurotensin-induced behaviour and changes in dopaminergic transmissionQ48146775
Turning behavior induced by intrastriatal injection of neurotensin in mice: sensitivity to non-peptide neurotensin antagonistsQ48206993
Neurotensin in the human brainQ48222321
The interaction of neurotensin with dopaminergic pathways in the central nervous system: basic neurobiology and implications for the pathogenesis and treatment of schizophreniaQ48421817
P433issue2-3
P407language of work or nameEnglishQ1860
P304page(s)91-4
P577publication date1996-05-20
P1433published inFEBS LettersQ1388051
P1476titleMolecular cloning of a levocabastine-sensitive neurotensin binding site
P478volume386

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cites work (P2860)
Q38895540A Review of the Role of Neurotensin and Its Receptors in Colorectal Cancer
Q33221326A novel form of neurotensin post-translationally modified by arginylation
Q30584554Activation of neurotensin receptor type 1 attenuates locomotor activity
Q41016202Activation of receptor gene transcription is required to maintain cell sensitization after agonist exposure. Study on neurotensin receptor.
Q40962965An antagonistic monoclonal antibody (B-N6) specific for the human neurotensin receptor-1.
Q37845684Anticonvulsant neuropeptides as drug leads for neurological diseases
Q44864832Automated large-scale purification of a G protein-coupled receptor for neurotensin
Q90720089Beneficial Effects of Neurotensin in Murine Model of Hapten-Induced Asthma
Q44260116Blockade of nicotine-induced locomotor sensitization by a novel neurotensin analog in rats
Q28536254Bright fluorescence monitoring system utilizing Zoanthus sp. green fluorescent protein (ZsGreen) for human G-protein-coupled receptor signaling in microbial yeast cells
Q48486157Characterization of binding sites of a new neurotensin receptor antagonist, [3H]SR 142948A, in the rat brain.
Q35041047Characterization of high affinity neurotensin receptor NTR1 in HL-60 cells and its down regulation during granulocytic differentiation
Q34110269Characterization of the profile of neurokinin-2 and neurotensin receptor antagonists in the mouse defense test battery.
Q30477036Chronic NT69L potently prevents drug-induced disruption of prepulse inhibition without causing tolerance
Q41922306Chronic, but not acute, dosing of antipsychotic drugs alters neurotensin binding in rat brain regions
Q48472876Common quantitative trait loci for alcohol-related behaviors and CNS neurotensin measures: voluntary ethanol consumption
Q93053579Conformational transitions of a neurotensin receptor 1-Gi1 complex
Q22003900Correlative ultrastructural distribution of neurotensin receptor proteins and binding sites in the rat substantia nigra
Q39253697Development of a metabolically stable neurotensin receptor 2 (NTS2) ligand
Q48794750Differential binding profile and internalization process of neurotensin via neuronal and glial receptors
Q48271028Differential ontogenetic patterns of levocabastine-sensitive neurotensin NT2 receptors and of NT1 receptors in the rat brain revealed by in situ hybridization
Q47973062Distinct functional characteristics of levocabastine sensitive rat neurotensin NT2 receptor expressed in Chinese hamster ovary cells
Q28580142Distribution of the neurotensin receptor NTS1 in the rat CNS studied using an amino-terminal directed antibody
Q50189472Diverse actions of the modulatory peptide neurotensin on central synaptic transmission.
Q33704191Does neurotensin mediate the effects of antipsychotic drugs?
Q48962597Effects of SR 48692 on neurotensin-induced calcium-activated chloride currents in the Xenopus oocyte expression system: agonist-like activity on the levocabastine-sensitive neurotensin receptor and absence of antagonist effect on the levocabastine i
Q73455068Effects of a novel neurotensin peptide analog given extracranially on CNS behaviors mediated by apomorphine and haloperidol
Q28582047Effects of neurotensin on discharge rates of rat suprachiasmatic nucleus neurons in vitro
Q41442335Effects of pallidal neurotensin on haloperidol-induced parkinsonian catalepsy: behavioral and electrophysiological studies
Q46667667Electrophysiological evidence for putative subtypes of neurotensin receptors in guinea-pig mesencephalic dopaminergic neurons
Q30426586Elucidating the role of neurotensin in the pathophysiology and management of major mental disorders.
Q37451908Endogenous CNS expression of neurotensin and neurotensin receptors is altered during the postpartum period in outbred mice
Q73964518Evidence for a role of endogenous neurotensin in the initiation of amphetamine sensitization
Q48443213Evidence for additional neurotensin receptor subtypes: neurotensin analogs that distinguish between neurotensin-mediated hypothermia and antinociception
Q73103514Evidence for the dual coupling of the rat neurotensin receptor with pertussis toxin-sensitive and insensitive G-proteins
Q42241976Existence of two translation initiation sites leading to the expression of two proteins from the rat high-affinity neurotensin-receptor cDNA: possible regulation by the 5' end non-coding region
Q48270929Expression of the 100-kDa neurotensin receptor sortilin during mouse embryonal development
Q39025439GPR39-1b, the 5-transmembrane isoform of GPR39 interacts with neurotensin receptor NTSR1 and modifies its function
Q46691563Heightened amygdala long-term potentiation in neurotensin receptor type-1 knockout mice
Q48572852High affinity neurotensin receptor mRNA distribution in rat brain and peripheral tissues. Analysis by quantitative RT-PCR.
Q30475347Hyperactivity of the dopaminergic system in NTS1 and NTS2 null mice
Q40473940Identification and functional characterization of a 5-transmembrane domain variant isoform of the NTS2 neurotensin receptor in rat central nervous system.
Q34435669Identification of 1-({[1-(4-fluorophenyl)-5-(2-methoxyphenyl)-1H-pyrazol-3-yl]carbonyl}amino)cyclohexane carboxylic acid as a selective nonpeptide neurotensin receptor type 2 compound
Q34164864Identification of N-[(5-{[(4-methylphenyl)sulfonyl]amino}-3-(trifluoroacetyl)-1H-indol-1-yl)acetyl]-l-leucine (NTRC-824), a neurotensin-like nonpeptide compound selective for the neurotensin receptor type 2
Q49724180Identification of Neurotensin Receptor Expressing Cells in the Ventral Tegmental Area across the Lifespan.
Q73316773Identification of residues involved in neurotensin binding and modeling of the agonist binding site in neurotensin receptor 1
Q48319054Identification of the receptor subtype involved in the analgesic effect of neurotensin
Q44441072Immunohistochemical distribution of NTS2 neurotensin receptors in the rat central nervous system
Q45241562Impact of the proline residue on ligand binding of neurotensin receptor 2 (NTS2)-selective peptide-peptoid hybrids
Q43832345Impaired G protein coupling of the neurotensin receptor 1 by mutations in extracellular loop 3.
Q51594469In Silico Investigation of the Neurotensin Receptor 1 Binding Site: Overlapping Binding Modes for Small Molecule Antagonists and the Endogenous Peptide Agonist.
Q35029237In vitro functional evidence of different neurotensin-receptors modulating the motor response of human colonic muscle strips
Q48456486In vivo studies with low doses of levocabastine and diphenhydramine, but not pyrilamine, antagonize neurotensin-mediated antinociception
Q34680977Increased ethanol consumption and preference in mice lacking neurotensin receptor type 2
Q42165142Interaction of xenin with the neurotensin receptor of guinea pig enteral smooth muscles
Q44105576Interaction of xenin with the neurotensin receptor of guinea pig enteral smooth muscles
Q28211177Involvement of the neurotensin receptor-3 in the neurotensin-induced migration of human microglia
Q37099122ML314: A Biased Neurotensin Receptor Ligand for Methamphetamine Abuse
Q41006768Mechanisms of regulation of neurotensin receptors
Q28584277Modulation of the interaction between neurotensin receptor NTS1 and Gq protein by lipid
Q39612931Molecular characterization of structure and tissue distribution of chicken neurotensin receptor
Q34918519Molecular imaging of gene expression and protein function in vivo with PET and SPECT.
Q42541576Mutagenesis and modeling of the neurotensin receptor NTR1. Identification of residues that are critical for binding SR 48692, a nonpeptide neurotensin antagonist
Q40589593NT agonist regulates expression of nuclear high-affinity neurotensin receptors.
Q30477584NT79: A novel neurotensin analog with selective behavioral effects
Q34275762Neuropeptide receptor ligands as drugs for psychiatric diseases: the end of the beginning?
Q48729574Neurotensin agonist induces differential regulation of neurotensin receptor mRNA. Identification of distinct transcriptional and post-transcriptional mechanisms.
Q35152140Neurotensin agonists: possible drugs for treatment of psychostimulant abuse
Q36540348Neurotensin and its high affinity receptor 1 as a potential pharmacological target in cancer therapy
Q36449538Neurotensin and its receptors in the control of glucose homeostasis
Q28138527Neurotensin and neurotensin receptors
Q27322643Neurotensin co-expressed in orexin-producing neurons in the lateral hypothalamus plays an important role in regulation of sleep/wakefulness states
Q46856938Neurotensin depolarizes cholinergic and a subset of non-cholinergic septal/diagonal band neurons by stimulating neurotensin-1 receptors
Q46704914Neurotensin enhances GABAergic activity in rat hippocampus CA1 region by modulating L-type calcium channels
Q40986329Neurotensin enhances agonist-induced cAMP accumulation in PC3 cells via Ca2+ -dependent adenylyl cyclase(s).
Q89713011Neurotensin in reward processes
Q34091437Neurotensin induces mating in Saccharomyces cerevisiae cells that express human neurotensin receptor type 1 in place of the endogenous pheromone receptor
Q22008527Neurotensin is an antagonist of the human neurotensin NT2 receptor expressed in Chinese hamster ovary cells
Q37461576Neurotensin modulates pacemaker activity in interstitial cells of Cajal from the mouse small intestine
Q33695438Neurotensin receptor type 1 regulates ethanol intoxication and consumption in mice
Q42489739Neurotensin regulates cortical glutamate transmission by modulating N-methyl-D-aspartate receptor functional activity: an in vivo microdialysis study
Q28579384Neurotensin regulates intracellular calcium in ventral tegmental area astrocytes: evidence for the involvement of multiple receptors
Q37417949Neurotensin stimulates sortilin and mTOR in human microglia inhibitable by methoxyluteolin, a potential therapeutic target for autism
Q77115463Neurotensin type 1 receptor-mediated activation of krox24, c-fos and Elk-1: preventing effect of the neurotensin antagonists SR 48692 and SR 142948
Q35922475Neurotensin-induced proinflammatory signaling in human colonocytes is regulated by β-arrestins and endothelin-converting enzyme-1-dependent endocytosis and resensitization of neurotensin receptor 1.
Q39026861Neurotensin-produced antinociception in the rostral ventromedial medulla is partially mediated by spinal cord norepinephrine
Q34060785Neurotensin: peptide for the next millennium
Q41633181Nonpeptide antagonists of neuropeptide receptors: tools for research and therapy.
Q39337728Oncogenic role of neurotensin and neurotensin receptors in various cancers.
Q36390910Peptide nucleic acids targeted to the neurotensin receptor and administered i.p. cross the blood-brain barrier and specifically reduce gene expression
Q46123434Peripheral and central administration of xenin and neurotensin suppress food intake in rodents.
Q43588690Pharmacological properties of the mouse neurotensin receptor 3. Maintenance of cell surface receptor during internalization of neurotensin
Q57042701Pharmacological, molecular and functional characterization of glial neurotensin receptors
Q28575741Pharmacology and functional properties of NTS2 neurotensin receptors in cerebellar granule cells
Q28271138Potent spinal analgesia elicited through stimulation of NTS2 neurotensin receptors
Q24533549Propeptide cleavage conditions sortilin/neurotensin receptor-3 for ligand binding
Q34286857Receptor trafficking via the perinuclear recycling compartment accompanied by cell division is necessary for permanent neurotensin cell sensitization and leads to chronic mitogen-activated protein kinase activation
Q64102487Regional and Cellular Mapping of Sortilin Immunoreactivity in Adult Human Brain
Q36915456Regulation of the neurotensin NT(1) receptor in the developing rat brain following chronic treatment with the antagonist SR 48692
Q30395034Repeated effects of the neurotensin receptor agonist PD149163 in three animal tests of antipsychotic activity: assessing for tolerance and cross-tolerance to clozapine
Q47172685Role of central neurotensin in regulating feeding: Implications for the development and treatment of body weight disorders
Q31942539SR48692 is a neurotensin receptor antagonist which inhibits the growth of small cell lung cancer cells
Q42478437Sequences required for induction of neurotensin receptor gene expression during neuronal differentiation of N1E-115 neuroblastoma cells
Q28205453Sortilin/neurotensin receptor-3: a new tool to investigate neurotensin signaling and cellular trafficking?
Q38339934Specific gene blockade shows that peptide nucleic acids readily enter neuronal cells in vivo
Q74038553Stimulation of cell-surface urokinase-type plasminogen activator activity and cell migration in vascular endothelial cells by a novel hexapeptide analogue of neurotensin
Q42516494Stress-induced activation of median raphe serotonergic neurons in rats is potentiated by the neurotensin antagonist, SR 48692.
Q28582782Striatal NTS1 , dopamine D2 and NMDA receptor regulation of pallidal GABA and glutamate release--a dual-probe microdialysis study in the intranigral 6-hydroxydopamine unilaterally lesioned rat
Q27681431Structure of signaling-competent neurotensin receptor 1 obtained by directed evolution in Escherichia coli
Q27674395Structure of the agonist-bound neurotensin receptor
Q42472841Synergistic effects of neurotensin and beta-adrenergic agonist on 3,5-cyclic adenosine monophosphate accumulation and DNA synthesis in prostate cancer PC3 cells
Q22003873The 100-kDa neurotensin receptor is gp95/sortilin, a non-G-protein-coupled receptor
Q35977626The conformation of neurotensin bound to its G protein-coupled receptor
Q44178878The effects of diphenhydramine and SR142948A on periaqueductal gray neurons and on the interactions between the medial preoptic nucleus and the periaqueductal gray
Q28308189The identification of nonpeptide neurotensin receptor partial agonists from the potent antagonist SR48692 using a calcium mobilization assay
Q43846382The neurotensin receptor antagonist, SR48692, attenuates the expression of amphetamine-induced behavioural sensitisation in mice.
Q73098647The partial agonist properties of levocabastine in neurotensin-induced analgesia
Q38920728The potential of neurotensin secreted from neuroendocrine tumor cells to promote gelsolin-mediated invasiveness of prostate adenocarcinoma cells
Q36544566The role of neurotensin in central nervous system pathophysiology: what is the evidence?
Q34463402The role of neurotensin in the pathophysiology of schizophrenia and the mechanism of action of antipsychotic drugs
Q33785381Therapeutic index of H1-antihistamines: example of cetirizine
Q47798016Tissue distribution and cellular localization of the levocabastine-sensitive neurotensin receptor mRNA in adult rat brain
Q34733947Transient and stable expression of the neurotensin receptor NTS1: a comparison of the baculovirus-insect cell and the T-REx-293 expression systems
Q77744006X-ray structural characterization of SR 142948, a novel potent synthetic neurotensin receptor antagonist