Candidate locus analysis of the TERT-CLPTM1L cancer risk region on chromosome 5p15 identifies multiple independent variants associated with endometrial cancer risk

scientific article published in February 2015

Candidate locus analysis of the TERT-CLPTM1L cancer risk region on chromosome 5p15 identifies multiple independent variants associated with endometrial cancer risk is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1018384724
P356DOI10.1007/S00439-014-1515-4
P3181OpenCitations bibliographic resource ID4733200
P932PMC publication ID4291520
P698PubMed publication ID25487306
P5875ResearchGate publication ID269416404

P50authorAnne-Lise Børresen-DaleQ11958220
Ingo B. RunnebaumQ1336242
Julian PetoQ6307461
Ian TomlinsonQ63213090
Peter A. FaschingQ64005064
Arif B. EkiciQ64409983
Annika LindblomQ64516098
Julie M. CunninghamQ67440680
Jianjun LiuQ68692572
Matthias W. BeckmannQ72940290
Deborah ThompsonQ73218846
Jenny Chang-ClaudeQ21263057
Alison DunningQ30506457
Graham GilesQ30524411
Shirley HodgsonQ15995134
Tormund S NjølstadQ57568095
Douglas F. EastonQ59812154
Emma ThamQ59941710
Anthony SwerdlowQ60492223
Paul D P PharoahQ61822938
Per HallQ62593354
Alfons MeindlQ63015490
Fergus J. CouchQ63018779
Jeroen DepreeuwQ114341800
Attila TeomanQ114374868
Nicholas WentzensenQ114374921
Kaltin FergusonQ114374951
Lieve CoenegrachtsQ114374955
Diether LambrechtsQ26923514
Helga SalvesenQ27506003
Kamila CzeneQ28484009
Angela CoxQ28484012
Hiltrud BrauchQ28484013
Barbara BurwinkelQ28484015
Hermann BrennerQ28958315
Fiona BruinsmaQ73472233
Nichola JohnsonQ74014116
Janet E. OlsonQ78318964
Brooke L FridleyQ86514651
Matthias RuebnerQ87831504
Jodie N PainterQ88243691
Ellen L GoodeQ88243694
Frederik MarméQ88268377
Luis G Carvajal-CarmonaQ88334637
Frédéric AmantQ90141632
Peter HillemannsQ91084009
Jonathan P TyrerQ91084019
Miriam MintsQ94995287
Zhihua ChenQ97436528
Manjeet K BollaQ114270702
Karen A PooleyQ114292600
Mitul ShahQ114292631
Kimberley M HowarthQ114341763
Maggie GormanQ114341767
Geoffrey OttonQ114341794
Tony ProiettoQ114341795
Katie AshtonQ114341796
Sean C DowdyQ114341797
Henrica M J WernerQ114341798
Stefanie SchrauwenQ114341799
Jingmei LiQ37371985
Boris WinterhoffQ38291602
Rachel Palmieri WeberQ38296800
Jone TrovikQ42385777
Amanda SpurdleQ45904058
Joe DennisQ56875626
Matthieu MoisseQ47503138
Tracy O'MaraQ47503150
Matthias DürstQ50033778
Felicity LoseQ51102418
Stefan P RennerQ51833341
Alexander HeinQ52723502
Shahana AhmedQ54208457
Melissa C. SoutheyQ55446228
Jonathan BeesleyQ56524232
Anja RudolphQ56722646
John HopperQ56726496
Kyriaki MichailidouQ37070465
Aida Karina DieffenbachQ37075433
Thilo DörkQ37342847
Vessela KristensenQ37344701
P2093author name stringQin Wang
Rodney J Scott
Timothy Cheng
Angela Jones
Lynn Martin
Catherine S Healey
Nicholas Orr
Ofra Wersäll
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Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33Q23924183
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A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33Q24597370
New common variants affecting susceptibility to basal cell carcinomaQ24615109
Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomasQ24617520
Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancerQ24633316
Common 5p15.33 and 6p21.33 variants influence lung cancer riskQ24646182
Lung cancer susceptibility locus at 5p15.33Q24649980
A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinomaQ24657797
Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association studyQ29417074
Genome-wide association study identifies a common variant associated with risk of endometrial cancerQ29417135
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HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variantsQ29614906
Genome-wide association study identifies five susceptibility loci for gliomaQ29614921
Sequence variants at the TERT-CLPTM1L locus associate with many cancer typesQ29614935
Two variants on chromosome 17 confer prostate cancer risk and the one in TCF2 protects against type 2 diabetesQ56968912
Using Penalised Logistic Regression to Fine Map HLA Variants for Rheumatoid ArthritisQ57393096
Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer riskQ27008356
A novel gene, CRR9, which was up-regulated in CDDP-resistant ovarian tumor cell line, was associated with apoptosisQ28143357
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Multiple loci identified in a genome-wide association study of prostate cancerQ28943507
Large-scale genotyping identifies 41 new loci associated with breast cancer riskQ29416989
Variants near DMRT1, TERT and ATF7IP are associated with testicular germ cell cancerQ29417028
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High frequency strand slippage mutations in CTCF in MSI-positive endometrial cancers.Q37624309
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Differential gene expression profile in endometrioid and nonendometrioid endometrial carcinoma: STK15 is frequently overexpressed and amplified in nonendometrioid carcinomas.Q47590656
Expression of TERT in early premalignant lesions and a subset of cells in normal tissuesQ47991825
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Microarray analysis reveals distinct gene expression profiles among different histologic types of endometrial cancer.Q53383860
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Multiple genetic variants in telomere pathway genes and breast cancer riskQ33522519
Hypomethylation of the CTCFL/BORIS promoter and aberrant expression during endometrial cancer progression suggests a role as an Epi-driver gene.Q33572253
CLPTM1L promotes growth and enhances aneuploidy in pancreatic cancer cellsQ33648848
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Microarray analysis reveals distinct gene expression profiles among different tumor histology, stage and disease outcomes in endometrial adenocarcinomaQ34287768
CRR9/CLPTM1L regulates cell survival signaling and is required for Ras transformation and lung tumorigenesisQ34394189
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Fine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer riskQ35063160
A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor-negative breast cancerQ35755874
Genetic epidemiology of cancer: from families to heritable genesQ35858666
Deregulation of RAD21 and RUNX1 expression in endometrial cancer.Q36423904
Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expressionQ36856343
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancerQ36897003
GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancerQ36956156
Integrated genomic profiling of endometrial carcinoma associates aggressive tumors with indicators of PI3 kinase activationQ37140110
Two estrogen-related variants in CYP19A1 and endometrial cancer risk: a pooled analysis in the Epidemiology of Endometrial Cancer ConsortiumQ37157438
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectendometrial cancerQ944777
P304page(s)231-45
P577publication date2015-02-01
P1433published inHuman GeneticsQ5937167
P1476titleCandidate locus analysis of the TERT-CLPTM1L cancer risk region on chromosome 5p15 identifies multiple independent variants associated with endometrial cancer risk
P478volume134

Reverse relations

cites work (P2860)
Q37005064A Common Variant at the 14q32 Endometrial Cancer Risk Locus Activates AKT1 through YY1 Binding
Q58804285A study of the application of TAP combined with transvaginal ultrasound in the diagnosis of early-stage endometrial cancer
Q36729524Common variations in TERT-CLPTM1L locus are reproducibly associated with the risk of nasopharyngeal carcinoma in Chinese populations
Q36026731Comprehensive genetic assessment of the ESR1 locus identifies a risk region for endometrial cancer
Q30234614Endometrial cancer gene panels: clinical diagnostic vs research germline DNA testing
Q92137491Exome-Wide Rare Variant Analysis From the DiscovEHR Study Identifies Novel Candidate Predisposition Genes for Endometrial Cancer
Q40077748Family history of cancer predicts endometrial cancer risk independently of Lynch Syndrome: Implications for genetic counselling.
Q37002930Five endometrial cancer risk loci identified through genome-wide association analysis
Q42366538Functional dissection of breast cancer risk-associated TERT promoter variants
Q55262410Genetic polymorphisms in the TERT gene and susceptibility to non-small cell lung cancer in a Chinese Han population.
Q29248191Genetic variants in TERT are associated with risk of gastric cancer in a Chinese Han population
Q33598001Genome-wide analysis of gynecologic cancer: The Cancer Genome Atlas in ovarian and endometrial cancer
Q26745549Human Specific Regulation of the Telomerase Reverse Transcriptase Gene
Q57170142Identification of nine new susceptibility loci for endometrial cancer
Q41642490Integrated genomic analyses reveal frequent TERT aberrations in acral melanoma
Q36333368Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1.
Q26765235Pancreatic Cancer Genetics
Q60931016Risk and prognostic factors for endometrial carcinoma after diagnosis of breast or Lynch-associated cancers-A population-based analysis

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