| scholarly article | Q13442814 |
| P2093 | author name string | N Motoyama | |
| K Nakayama | |||
| K Ikeda | |||
| K Tominaga | |||
| T Tsukiyama | |||
| M Nakanishi | |||
| H Takai | |||
| H Nagahama | |||
| Y A Minamishima | |||
| P2860 | cites work | Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine. | Q52536369 |
| rad-dependent response of the chk1-encoded protein kinase at the DNA damage checkpoint. | Q53457110 | ||
| Cdc25 Mitotic Inducer Targeted by Chk1 DNA Damage Checkpoint Kinase | Q57233839 | ||
| Replication checkpoint requires phosphorylation of the phosphatase Cdc25 by Cds1 or Chk1 | Q59061022 | ||
| Checkpoints Take the Next Step | Q63383728 | ||
| Mutation of fission yeast cell cycle control genes abolishes dependence of mitosis on DNA replication | Q68929092 | ||
| Alteration of cell cycle-dependent histone phosphorylations by okadaic acid. Induction of mitosis-specific H3 phosphorylation and chromatin condensation in mammalian interphase cells | Q71142856 | ||
| Ordering S phase and M phase in the cell cycle | Q72790820 | ||
| Role of human Cds1 (Chk2) kinase in DNA damage checkpoint and its regulation by p53 | Q73107109 | ||
| Control of the DNA damage checkpoint by chk1 and rad53 protein kinases through distinct mechanisms | Q73153090 | ||
| Cell-cycle-dependent and ATM-independent expression of human Chk1 kinase | Q77954362 | ||
| Linkage of ATM to cell cycle regulation by the Chk2 protein kinase | Q22008502 | ||
| Human wee1 maintains mitotic timing by protecting the nucleus from cytoplasmically activated Cdc2 kinase | Q24311353 | ||
| A single ataxia telangiectasia gene with a product similar to PI-3 kinase | Q24323579 | ||
| DNA repair mutants defining G2 checkpoint pathways in Schizosaccharomyces pombe | Q24555694 | ||
| S-phase-specific activation of Cds1 kinase defines a subpathway of the checkpoint response in Schizosaccharomyces pombe | Q24607761 | ||
| A human Cds1-related kinase that functions downstream of ATM protein in the cellular response to DNA damage | Q24651421 | ||
| Checkpoints: controls that ensure the order of cell cycle events | Q28131705 | ||
| hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response | Q28139139 | ||
| Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway | Q28141324 | ||
| Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2 | Q28236543 | ||
| DNA-replication checkpoint control at the Drosophila midblastula transition | Q28243128 | ||
| Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25 | Q28247761 | ||
| Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216 | Q28247771 | ||
| Brca2 is required for embryonic cellular proliferation in the mouse | Q28508546 | ||
| Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene | Q28512170 | ||
| ATR disruption leads to chromosomal fragmentation and early embryonic lethality | Q28591433 | ||
| Disappearance of the lymphoid system in Bcl-2 homozygous mutant chimeric mice | Q28593186 | ||
| Cytoplasmic localization of human cdc25C during interphase requires an intact 14-3-3 binding site | Q28610026 | ||
| Cell cycle checkpoints: preventing an identity crisis | Q29547644 | ||
| The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse | Q29618622 | ||
| Basis for the checkpoint signal specificity that regulates Chk1 and Cds1 protein kinases | Q33652271 | ||
| Exit from G0 and entry into the cell cycle of cells expressing p21Sdi1 antisense RNA. | Q34324961 | ||
| Fission yeast chk1 protein kinase links the rad checkpoint pathway to cdc2. | Q34365395 | ||
| Binding of 14-3-3 proteins and nuclear export control the intracellular localization of the mitotic inducer Cdc25. | Q35203445 | ||
| Overexpression of a kinase-inactive ATR protein causes sensitivity to DNA-damaging agents and defects in cell cycle checkpoints | Q41063544 | ||
| Nuclear localization of Cdc25 is regulated by DNA damage and a 14-3-3 protein | Q46098415 | ||
| The Drosophila ATM homologue Mei-41 has an essential checkpoint function at the midblastula transition. | Q52177829 | ||
| P433 | issue | 12 | |
| P921 | main subject | Checkpoint kinase 1 | Q21495077 |
| P304 | page(s) | 1439-1447 | |
| P577 | publication date | 2000-06-01 | |
| P1433 | published in | Genes & Development | Q1524533 |
| P1476 | title | Aberrant cell cycle checkpoint function and early embryonic death in Chk1(-/-) mice | |
| P478 | volume | 14 |
| Q24540067 | A DNA damage-regulated BRCT-containing protein, TopBP1, is required for cell survival |
| Q48104450 | A Role for the Twins Protein Phosphatase (PP2A-B55) in the Maintenance of Drosophila Genome Integrity |
| Q36908567 | A cell-based screen identifies ATR inhibitors with synthetic lethal properties for cancer-associated mutations. |
| Q39142830 | A conserved proliferating cell nuclear antigen-interacting protein sequence in Chk1 is required for checkpoint function |
| Q36974075 | A dual molecular analogue tuner for dissecting protein function in mammalian cells |
| Q35632581 | A phospho-proteomic screen identifies substrates of the checkpoint kinase Chk1. |
| Q43106462 | A role for Chk1 in blocking transcriptional elongation of p21 RNA during the S-phase checkpoint |
| Q47658768 | A role for caspase-2 in sphingosine kinase 1 proteolysis in response to doxorubicin in breast cancer cells - implications for the CHK1-suppressed pathway |
| Q36738836 | A subset of cancer cell lines is acutely sensitive to the Chk1 inhibitor MK-8776 as monotherapy due to CDK2 activation in S phase |
| Q35959358 | ATM and genome maintenance: defining its role in breast cancer susceptibility |
| Q89520185 | ATM, ATR and DNA-PKcs kinases-the lessons from the mouse models: inhibition ≠ deletion |
| Q33396987 | ATR and Chk1 suppress a caspase-3-dependent apoptotic response following DNA replication stress |
| Q34987777 | ATR kinase activation in G1 phase facilitates the repair of ionizing radiation-induced DNA damage |
| Q46751337 | ATR kinase inhibition induces unscheduled origin firing through a Cdc7-dependent association between GINS and And-1. |
| Q24550952 | ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1 |
| Q33700754 | Activation of CHK1 in Supporting Cells Indirectly Promotes Hair Cell Survival |
| Q34443534 | An ATR- and Chk1-dependent S checkpoint inhibits replicon initiation following UVC-induced DNA damage |
| Q41067688 | An essential role for MCL-1 in ATR-mediated CHK1 phosphorylation |
| Q35825997 | An extra allele of Chk1 limits oncogene-induced replicative stress and promotes transformation |
| Q24656275 | Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro |
| Q33635896 | Ataxin-3 promotes genome integrity by stabilizing Chk1. |
| Q39303724 | Autoregulatory mechanisms of phosphorylation of checkpoint kinase 1. |
| Q34426013 | B-Myb is critical for proper DNA duplication during an unperturbed S phase in mouse embryonic stem cells |
| Q24554317 | BRCT domain-containing protein PTIP is essential for progression through mitosis |
| Q92320326 | Basal CHK1 activity safeguards its stability to maintain intrinsic S-phase checkpoint functions |
| Q28363027 | Blocking Chk1 expression induces apoptosis and abrogates the G2 checkpoint mechanism |
| Q50423666 | CHEK1 coordinates DNA damage signaling and meiotic progression in the male germline of mice. |
| Q41840512 | CRL4(CDT2) targets CHK1 for PCNA-independent destruction |
| Q36623319 | Cell proliferation potency is independent of FGF4 signaling in trophoblast stem cells derived from androgenetic embryos |
| Q35883943 | Checkpoint Kinase 1 Activation Enhances Intestinal Epithelial Barrier Function via Regulation of Claudin-5 Expression |
| Q35033125 | Checkpoint kinase 1 (Chk1) is required for mitotic progression through negative regulation of polo-like kinase 1 (Plk1) |
| Q35657580 | Checkpoint kinase 1 (Chk1)-short is a splice variant and endogenous inhibitor of Chk1 that regulates cell cycle and DNA damage checkpoints |
| Q28287480 | Checkpoint kinase 1 in DNA damage response and cell cycle regulation |
| Q92399928 | Checkpoint kinase 1 is essential for fetal and adult hematopoiesis |
| Q48250645 | Checkpoint kinase 1 is essential for normal B cell development and lymphomagenesis. |
| Q38594084 | Checkpoint kinase 1 negatively regulates somatic hypermutation |
| Q42541714 | Checkpoint kinase 2 is required for efficient immunoglobulin diversification |
| Q37555069 | Checkpoint kinase inhibitor AZD7762 strongly sensitises urothelial carcinoma cells to gemcitabine |
| Q26863501 | Chemotherapeutic compounds targeting the DNA double-strand break repair pathways: the good, the bad, and the promising |
| Q40985225 | Chk1 Inhibition of the Replication Factor Drf1 Guarantees Cell-Cycle Elongation at the Xenopus laevis Mid-blastula Transition. |
| Q33824746 | Chk1 and Cds1: linchpins of the DNA damage and replication checkpoint pathways. |
| Q42118108 | Chk1 deficiency in the mouse small intestine results in p53-independent crypt death and subsequent intestinal compensation |
| Q38633360 | Chk1 inhibits E2F6 repressor function in response to replication stress to maintain cell-cycle transcription |
| Q39644973 | Chk1 is activated transiently and targets Cdc25A for degradation at the Xenopus midblastula transition |
| Q52576772 | Chk1 is required for spindle checkpoint function. |
| Q41847676 | Chk1 regulates the density of active replication origins during the vertebrate S phase. |
| Q34563205 | Chk1 requirement for high global rates of replication fork progression during normal vertebrate S phase |
| Q21203552 | Chk1 suppressed cell death |
| Q53354195 | Chk1-cyclin A/Cdk1 axis regulates origin firing programs in mammals. |
| Q39698998 | Chk1-deficient tumour cells are viable but exhibit multiple checkpoint and survival defects |
| Q40474908 | Chk1-dependent S-M checkpoint delay in vertebrate cells is linked to maintenance of viable replication structures. |
| Q28396027 | Chk2 deficiency in Myc overexpressing lymphoma cells elicits a synergistic lethal response in combination with PARP inhibition |
| Q34149479 | Chk2-deficient mice exhibit radioresistance and defective p53-mediated transcription |
| Q37229377 | Cip/Kip cyclin-dependent protein kinase inhibitors and the road to polyploidy. |
| Q24670580 | Claspin operates downstream of TopBP1 to direct ATR signaling towards Chk1 activation |
| Q35657004 | Combined inhibition of the cell cycle related proteins Wee1 and Chk1/2 induces synergistic anti-cancer effect in melanoma. |
| Q34323837 | Control of DNA replication and chromosome ploidy by geminin and cyclin A |
| Q34241074 | Cooperative functions of Chk1 and Chk2 reduce tumour susceptibility in vivo |
| Q36127125 | Coupling cellular localization and function of checkpoint kinase 1 (Chk1) in checkpoints and cell viability |
| Q24292703 | Critical role for mouse Hus1 in an S-phase DNA damage cell cycle checkpoint |
| Q35676646 | Cross-talk between Chk1 and Chk2 in double-mutant thymocytes. |
| Q36029906 | DNA damage induces Chk1-dependent centrosome amplification. |
| Q35610725 | DNA damage response and spindle assembly checkpoint function throughout the cell cycle to ensure genomic integrity |
| Q28388312 | DNA damage response genes and the development of cancer metastasis |
| Q37187991 | DNA damage tolerance: a double-edged sword guarding the genome |
| Q24306945 | DNA damage-induced cell cycle checkpoint control requires CtIP, a phosphorylation-dependent binding partner of BRCA1 C-terminal domains |
| Q30495277 | DNA damage-induced cell death is enhanced by progression through mitosis |
| Q37233544 | DNA replication in early S phase pauses near newly activated origins |
| Q38496732 | DNA replication origin activation in space and time |
| Q24529007 | DNA-dependent phosphorylation of Chk1 and Claspin in a human cell-free system |
| Q24312094 | DTL/CDT2 is essential for both CDT1 regulation and the early G2/M checkpoint |
| Q41844691 | Death of p53-defective cells triggered by forced mitotic entry in the presence of DNA damage is not uniquely dependent on Caspase-2 or the PIDDosome |
| Q41283109 | Deletion of mouse rad9 causes abnormal cellular responses to DNA damage, genomic instability, and embryonic lethality |
| Q37367026 | Developmentally programmed endoreduplication in animals |
| Q38973685 | Differential response of normal and malignant urothelial cells to CHK1 and ATM inhibitors. |
| Q24644745 | Differentiation of trophoblast stem cells into giant cells is triggered by p57/Kip2 inhibition of CDK1 activity |
| Q34148137 | Dimerization of the ATRIP protein through the coiled-coil motif and its implication to the maintenance of stalled replication forks |
| Q28592343 | Disruption of Ini1 leads to peri-implantation lethality and tumorigenesis in mice |
| Q28590133 | Disruption of murine mp29/Syf2/Ntc31 gene results in embryonic lethality with aberrant checkpoint response |
| Q24538300 | Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints |
| Q28507942 | Disruption of the pelota gene causes early embryonic lethality and defects in cell cycle progression |
| Q35623428 | Embryonic cleavage cycles: how is a mouse like a fly? |
| Q33914335 | Enucleation of feeder cells and egg cells with psoralens |
| Q35221354 | Evolutionarily conserved role of nucleostemin: controlling proliferation of stem/progenitor cells during early vertebrate development |
| Q37142957 | Expanded roles for Chk1 in genome maintenance |
| Q37597842 | Exploiting synthetic lethal interactions for targeted cancer therapy |
| Q37341109 | Family cancer syndromes: inherited deficiencies in systems for the maintenance of genomic integrity |
| Q35794854 | From egg to gastrula: how the cell cycle is remodeled during the Drosophila mid-blastula transition |
| Q34168520 | Geminin deficiency causes a Chk1-dependent G2 arrest in Xenopus |
| Q46605059 | Genetic instability and mammary tumor formation in mice carrying mammary-specific disruption of Chk1 and p53. |
| Q35676284 | Genome maintenance defects in cultured cells and mice following partial inactivation of the essential cell cycle checkpoint gene Hus1. |
| Q54978319 | Genomic structure, expression, and functional characterization of checkpoint kinase 1 from Penaeus monodon. |
| Q37188498 | Glucose deprivation is associated with Chk1 degradation through the ubiquitin-proteasome pathway and effective checkpoint response to replication blocks |
| Q35637855 | Grp/DChk1 is required for G2-M checkpoint activation in Drosophila S2 cells, whereas Dmnk/DChk2 is dispensable |
| Q34121643 | Histone XH2AX is required for Xenopus anterior neural development: critical role of threonine 16 phosphorylation. |
| Q28595006 | Impaired mitotic progression and preimplantation lethality in mice lacking OMCG1, a new evolutionarily conserved nuclear protein |
| Q34072906 | Impaired tissue growth is mediated by checkpoint kinase 1 (CHK1) in the integrated stress response |
| Q35093054 | In vivo role of checkpoint kinase 2 in signaling telomere dysfunction |
| Q35650781 | Increased common fragile site expression, cell proliferation defects, and apoptosis following conditional inactivation of mouse Hus1 in primary cultured cells |
| Q31160033 | Inhibition of human Chk1 causes increased initiation of DNA replication, phosphorylation of ATR targets, and DNA breakage |
| Q42127933 | Initiation of Drosophila chorion gene amplification requires Claspin and mus101, whereas Claspin, but not mus101, plays a major role during elongation |
| Q60044506 | Kinase-dead ATR differs from ATR loss by limiting the dynamic exchange of ATR and RPA |
| Q35983115 | Kinase-independent function of checkpoint kinase 1 (Chk1) in the replication of damaged DNA. |
| Q38755992 | LC-MS/MS assay for the simultaneous quantitation of the ATM inhibitor AZ31 and the ATR inhibitor AZD6738 in mouse plasma |
| Q33240549 | Loss of Atrx affects trophoblast development and the pattern of X-inactivation in extraembryonic tissues |
| Q24676493 | Loss of Geminin induces rereplication in the presence of functional p53 |
| Q35149603 | Loss of compensatory pro-survival and anti-apoptotic modulator, IKKε, sensitizes ovarian cancer cells to CHEK1 loss through an increased level of p21. |
| Q37425607 | Mammalian Rif1 contributes to replication stress survival and homology-directed repair |
| Q28587270 | Mammalian TIMELESS and Tipin are evolutionarily conserved replication fork-associated factors |
| Q26826949 | Modeling the study of DNA damage responses in mice |
| Q33248434 | Murine Wee1 plays a critical role in cell cycle regulation and pre-implantation stages of embryonic development |
| Q93040664 | Novel CHK1 inhibitor MU380 exhibits significant single-agent activity in TP53-mutated chronic lymphocytic leukemia cells |
| Q28262425 | Novel regulation of checkpoint kinase 1: Is checkpoint kinase 1 a good candidate for anti-cancer therapy? |
| Q35640593 | Oncogenic stress sensitizes murine cancers to hypomorphic suppression of ATR |
| Q64113941 | Overexpression of Claspin and Timeless protects cancer cells from replication stress in a checkpoint-independent manner |
| Q28594718 | PLRG1 is an essential regulator of cell proliferation and apoptosis during vertebrate development and tissue homeostasis |
| Q37618107 | Pharmacologic ATM but not ATR kinase inhibition abrogates p21-dependent G1 arrest and promotes gastrointestinal syndrome after total body irradiation |
| Q35800291 | Phase I dose-escalation study of AZD7762, a checkpoint kinase inhibitor, in combination with gemcitabine in US patients with advanced solid tumors |
| Q34198570 | Phosphatases in the cellular response to DNA damage. |
| Q35131775 | Phosphorylation of Chk1 by ATR is antagonized by a Chk1-regulated protein phosphatase 2A circuit |
| Q35583204 | Phosphorylation of Minichromosome Maintenance 3 (MCM3) by Checkpoint Kinase 1 (Chk1) Negatively Regulates DNA Replication and Checkpoint Activation. |
| Q38974279 | Prospects for the Use of ATR Inhibitors to Treat Cancer. |
| Q34602599 | RNAi screen of the protein kinome identifies checkpoint kinase 1 (CHK1) as a therapeutic target in neuroblastoma |
| Q34362555 | RPA inhibition increases replication stress and suppresses tumor growth |
| Q24675123 | Radiation-induced phosphorylation of Chk1 at S345 is associated with p53-dependent cell cycle arrest pathways |
| Q37327269 | Reduced ATR or Chk1 expression leads to chromosome instability and chemosensitization of mismatch repair-deficient colorectal cancer cells |
| Q39915084 | Regulation of mitosis in response to damaged or incompletely replicated DNA require different levels of Grapes (Drosophila Chk1). |
| Q36557533 | Repair of topoisomerase I-mediated DNA damage |
| Q41789965 | Replication checkpoint: tuning and coordination of replication forks in s phase |
| Q34547673 | Replication licensing and the DNA damage checkpoint. |
| Q36931593 | Replication stress and cancer: it takes two to tango. |
| Q35206290 | Requirement for Atr in phosphorylation of Chk1 and cell cycle regulation in response to DNA replication blocks and UV-damaged DNA in Xenopus egg extracts |
| Q33924254 | Requirement of MTA1 in ATR-mediated DNA damage checkpoint function |
| Q59135972 | Role of Chk1 in the differentiation program of hematopoietic stem cells |
| Q28289548 | Roles of Chk1 in cell biology and cancer therapy |
| Q35116505 | S phase entry causes homocysteine-induced death while ataxia telangiectasia and Rad3 related protein functions anti-apoptotically to protect neurons |
| Q37936675 | Safeguarding genome integrity: the checkpoint kinases ATR, CHK1 and WEE1 restrain CDK activity during normal DNA replication |
| Q35150492 | Schizosaccharomyces pombe checkpoint response to DNA interstrand cross-links |
| Q35856701 | Specific role of Chk1 phosphorylations in cell survival and checkpoint activation |
| Q54536177 | Structural requirements of pyrimidine, thienopyridine and ureido thiophene carboxamide-based inhibitors of the checkpoint kinase 1: QSAR, docking, molecular dynamics analysis. |
| Q33999750 | Structure-specific DNA endonuclease Mus81/Eme1 generates DNA damage caused by Chk1 inactivation |
| Q38912800 | Suppression of CHK1 by ETS Family Members Promotes DNA Damage Response Bypass and Tumorigenesis |
| Q37497709 | Taking the time to make important decisions: the checkpoint effector kinases Chk1 and Chk2 and the DNA damage response |
| Q35920252 | Targeted deletion reveals an essential function for the telomere length regulator Trf1. |
| Q24610287 | Targeting ATR and Chk1 kinases for cancer treatment: a new model for new (and old) drugs |
| Q37376369 | Targeting radioresistant breast cancer cells by single agent CHK1 inhibitor via enhancing replication stress |
| Q28728010 | Targeting sphingosine kinase 1 in carcinoma cells decreases proliferation and survival by compromising PKC activity and cytokinesis |
| Q38817102 | Targeting the ATR-CHK1 Axis in Cancer Therapy |
| Q26795781 | Targeting the Checkpoint to Kill Cancer Cells |
| Q37659687 | Targeting the checkpoint kinase Chk1 in cancer therapy |
| Q36664049 | The ATR barrier to replication-born DNA damage. |
| Q42500271 | The Chk1/Cdc25A pathway as activators of the cell cycle in neuronal death induced by camptothecin. |
| Q37824549 | The DNA damage response: Balancing the scale between cancer and ageing |
| Q30486781 | The DNA-damage effector checkpoint kinase 1 is essential for chromosome segregation and cytokinesis |
| Q34617325 | The Drosophila chk2 gene loki is essential for embryonic DNA double-strand-break checkpoints induced in S phase or G2 |
| Q28589183 | The E4F protein is required for mitotic progression during embryonic cell cycles |
| Q28289090 | The cancer therapeutic potential of Chk1 inhibitors: how mechanistic studies impact on clinical trial design |
| Q24652535 | The combined status of ATM and p53 link tumor development with therapeutic response |
| Q38037329 | The effects of deregulated DNA damage signalling on cancer chemotherapy response and resistance |
| Q33925143 | The fission yeast Crb2/Chk1 pathway coordinates the DNA damage and spindle checkpoint in response to replication stress induced by topoisomerase I inhibitor |
| Q35205026 | The fork and the kinase: a DNA replication tale from a CHK1 perspective |
| Q24682656 | The human checkpoint Rad protein Rad17 is chromatin-associated throughout the cell cycle, localizes to DNA replication sites, and interacts with DNA polymerase |
| Q36168692 | The human checkpoint sensor Rad9-Rad1-Hus1 interacts with and stimulates DNA repair enzyme TDG glycosylase |
| Q33946976 | The human decatenation checkpoint. |
| Q34107413 | The interaction between checkpoint kinase 1 (Chk1) and the minichromosome maintenance (MCM) complex is required for DNA damage-induced Chk1 phosphorylation |
| Q24810132 | The multiple personalities of the regulatory subunit of protein kinase CK2: CK2 dependent and CK2 independent roles reveal a secret identity for CK2beta |
| Q28586313 | The murine ortholog of notchless, a direct regulator of the notch pathway in Drosophila melanogaster, is essential for survival of inner cell mass cells |
| Q36688959 | The orally active and bioavailable ATR kinase inhibitor AZD6738 potentiates the anti-tumor effects of cisplatin to resolve ATM-deficient non-small cell lung cancer in vivo |
| Q54538558 | Thresholds of replication stress signaling in cancer development and treatment. |
| Q35989104 | Tipin is required for stalled replication forks to resume DNA replication after removal of aphidicolin in Xenopus egg extracts |
| Q26745686 | Trial Watch: Targeting ATM-CHK2 and ATR-CHK1 pathways for anticancer therapy |
| Q24311887 | Tumor suppressor protein C53 antagonizes checkpoint kinases to promote cyclin-dependent kinase 1 activation |
| Q37988976 | Two sides of the Myc-induced DNA damage response: from tumor suppression to tumor maintenance |
| Q39795664 | U2OS cells lacking Chk1 undergo aberrant mitosis and fail to activate the spindle checkpoint |
| Q35094532 | UV irradiation induces a postreplication DNA damage checkpoint |
| Q42529464 | microRNAs regulate human embryonic stem cell division |
| Q39526736 | p53 down-regulates CHK1 through p21 and the retinoblastoma protein |
| Q37342444 | p53-deficient cells rely on ATM- and ATR-mediated checkpoint signaling through the p38MAPK/MK2 pathway for survival after DNA damage |
Search more.