| scholarly article | Q13442814 |
| P2093 | author name string | Xiao-Fan Wang | |
| Barbara K Goodman | |||
| Qinhong Wang | |||
| Ryohei Furumai | |||
| Melanie J Jardim | |||
| Timothy Wakeman | |||
| P2860 | cites work | MSH2 and ATR form a signaling module and regulate two branches of the damage response to DNA methylation | Q24301197 |
| The mismatch repair system is required for S-phase checkpoint activation | Q24321503 | ||
| ATR kinase activation mediated by MutSalpha and MutLalpha in response to cytotoxic O6-methylguanine adducts | Q24337520 | ||
| The role of chromosomal instability in tumor initiation | Q24541508 | ||
| Methylator-induced, mismatch repair-dependent G2 arrest is activated through Chk1 and Chk2 | Q24556572 | ||
| ATM-mediated stabilization of hMutL DNA mismatch repair proteins augments p53 activation during DNA damage | Q24564010 | ||
| Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint | Q24604730 | ||
| Lessons from hereditary colorectal cancer | Q28131788 | ||
| Targeted disruption of the cell-cycle checkpoint gene ATR leads to early embryonic lethality in mice | Q28143813 | ||
| ATR functions as a gene dosage-dependent tumor suppressor on a mismatch repair-deficient background | Q28274709 | ||
| Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2 | Q28277364 | ||
| Aberrant cell cycle checkpoint function and early embryonic death in Chk1(-/-) mice | Q28507011 | ||
| Tumour susceptibility and spontaneous mutation in mice deficient in Mlh1, Pms1 and Pms2 DNA mismatch repair | Q28508905 | ||
| ATR disruption leads to chromosomal fragmentation and early embryonic lethality | Q28591433 | ||
| ATR Regulates Fragile Site Stability | Q29303576 | ||
| ATM and related protein kinases: safeguarding genome integrity | Q29547735 | ||
| Cell cycle checkpoint signaling through the ATM and ATR kinases | Q29617837 | ||
| Genetic instability in colorectal cancers | Q29618711 | ||
| DNA mismatch repair and genetic instability | Q34090778 | ||
| Mutations within the hMLH1 and hPMS2 subunits of the human MutLalpha mismatch repair factor affect its ATPase activity, but not its ability to interact with hMutSalpha | Q34123282 | ||
| A systematic overview of chemotherapy effects in colorectal cancer | Q34301222 | ||
| A role for DNA mismatch repair in sensing and responding to fluoropyrimidine damage. | Q35567250 | ||
| Centrosome amplification, chromosome instability and cancer development | Q36298974 | ||
| Signalling cell cycle arrest and cell death through the MMR System | Q36333085 | ||
| Mutational targets in colorectal cancer cells with microsatellite instability. | Q36417805 | ||
| Radiosensitivity in ataxia-telangiectasia: a new explanation | Q36419108 | ||
| The multifaceted mismatch-repair system | Q36448284 | ||
| Common fragile sites as targets for chromosome rearrangements | Q36522587 | ||
| The genetics of hereditary colon cancer | Q36972251 | ||
| Genetic polymorphisms and micronucleus formation: a review of the literature. | Q37013864 | ||
| Cytogenetic characterization of two colon cell lines by using conventional G-banding, comparative genomic hybridization, and whole chromosome painting | Q38495887 | ||
| Regulation of p53 expression in response to 5-fluorouracil in human cancer RKO cells | Q40106667 | ||
| Mechanisms of acquired chemoresistance to 5-fluorouracil and tomudex: thymidylate synthase dependent and independent networks. | Q40205739 | ||
| Heterozygous ATR mutations in mismatch repair-deficient cancer cells have functional significance | Q40384815 | ||
| DNA mismatch repair-dependent response to fluoropyrimidine-generated damage. | Q40478691 | ||
| Role of hMLH1 promoter hypermethylation in drug resistance to 5-fluorouracil in colorectal cancer cell lines. | Q40582817 | ||
| Methylation tolerance in mismatch repair proficient cells with low MSH2 protein level | Q40735855 | ||
| Human chromosome 3 corrects mismatch repair deficiency and microsatellite instability and reduces N-methyl-N'-nitro-N-nitrosoguanidine tolerance in colon tumor cells with homozygous hMLH1 mutation | Q41448577 | ||
| Role of the hMLH1 DNA mismatch repair protein in fluoropyrimidine-mediated cell death and cell cycle responses. | Q43657362 | ||
| Mismatch repair-mediated G2/M arrest by 6-thioguanine involves the ATR-Chk1 pathway | Q44864127 | ||
| The relationship between global methylation level, loss of heterozygosity, and microsatellite instability in sporadic colorectal cancer | Q46073818 | ||
| Endonucleolytic function of MutLalpha in human mismatch repair. | Q50335575 | ||
| The significance of unstable chromosomes in colorectal cancer. | Q53376250 | ||
| Mutations in the ataxia telangiectasia and rad3-related-checkpoint kinase 1 DNA damage response axis in colon cancers. | Q53526795 | ||
| Chk1 frameshift mutation in sporadic and hereditary non-polyposis colorectal cancers with microsatellite instability. | Q53561491 | ||
| Depletion of CHK1, but not CHK2, induces chromosomal instability and breaks at common fragile sites. | Q53620700 | ||
| Somatic mutations in the DNA damage-response genes ATR and CHK1 in sporadic stomach tumors with microsatellite instability. | Q53989253 | ||
| Chromosomal instability and APC gene mutations in human sporadic colorectal adenomas | Q80582184 | ||
| P4510 | describes a project that uses | ImageJ | Q1659584 |
| P433 | issue | 17 | |
| P921 | main subject | colorectal cancer | Q188874 |
| DNA mismatch repair | Q2984243 | ||
| colorectal carcinoma | Q25493920 | ||
| P304 | page(s) | 3801-3809 | |
| P577 | publication date | 2009-07-01 | |
| P1433 | published in | Molecular Biology of the Cell | Q2338259 |
| P1476 | title | Reduced ATR or Chk1 expression leads to chromosome instability and chemosensitization of mismatch repair-deficient colorectal cancer cells | |
| P478 | volume | 20 |
| Q35423647 | Analysis of mutations that dissociate G(2) and essential S phase functions of human ataxia telangiectasia-mutated and Rad3-related (ATR) protein kinase |
| Q37457876 | Cdc6 contributes to cisplatin-resistance by activation of ATR-Chk1 pathway in bladder cancer cells |
| Q34110442 | Checkpoint signaling, base excision repair, and PARP promote survival of colon cancer cells treated with 5-fluorodeoxyuridine but not 5-fluorouracil |
| Q38716604 | DNA Damage Response-Independent Role for MDC1 in Maintaining Genomic Stability |
| Q34950524 | Distinct gene expression signatures in lynch syndrome and familial colorectal cancer type x. |
| Q93040638 | FLT3-ITD cooperates with Rac1 to modulate the sensitivity of leukemic cells to chemotherapeutic agents via regulation of DNA repair pathways |
| Q37188498 | Glucose deprivation is associated with Chk1 degradation through the ubiquitin-proteasome pathway and effective checkpoint response to replication blocks |
| Q36294441 | Identification of DNA repair pathways that affect the survival of ovarian cancer cells treated with a poly(ADP-ribose) polymerase inhibitor in a novel drug combination |
| Q39490275 | P38MAPK is a major determinant of the balance between apoptosis and autophagy triggered by 5-fluorouracil: implication in resistance |
| Q39554874 | Persimmon leaf extract inhibits the ATM activity during DNA damage response induced by Doxorubicin in A549 lung adenocarcinoma cells |
| Q35112912 | Poly(ADP-Ribose) polymerase inhibition synergizes with 5-fluorodeoxyuridine but not 5-fluorouracil in ovarian cancer cells. |
| Q38974279 | Prospects for the Use of ATR Inhibitors to Treat Cancer. |
| Q37976982 | Selective tumor killing based on specific DNA-damage response deficiencies |
| Q26745686 | Trial Watch: Targeting ATM-CHK2 and ATR-CHK1 pathways for anticancer therapy |
| Q42147670 | Zbtb1 Safeguards Genome Integrity and Prevents p53-Mediated Apoptosis in Proliferating Lymphoid Progenitors |
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