scholarly article | Q13442814 |
P2093 | author name string | Paul Modrich | |
Farid A Kadyrov | |||
Leonid Dzantiev | |||
Nicoleta Constantin | |||
P433 | issue | 2 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | DNA mismatch repair | Q2984243 |
P304 | page(s) | 297-308 | |
P577 | publication date | 2006-07-01 | |
P1433 | published in | Cell | Q655814 |
P1476 | title | Endonucleolytic function of MutLalpha in human mismatch repair. | |
P478 | volume | 126 |
Q33386923 | 6th International Immunoglobulin Symposium: poster presentations |
Q39947968 | A biochemically defined system for coding joint formation in V(D)J recombination |
Q24337655 | A genetic screen identifies FAN1, a Fanconi anemia-associated nuclease necessary for DNA interstrand crosslink repair |
Q38346714 | A human PMS2 homologue from Aquifex aeolicus stimulates an ATP-dependent DNA helicase |
Q64928626 | A mutation in the endonuclease domain of mouse MLH3 reveals novel roles for MutLγ during crossover formation in meiotic prophase I. |
Q36724317 | A mutation in the putative MLH3 endonuclease domain confers a defect in both mismatch repair and meiosis in Saccharomyces cerevisiae |
Q33349553 | A new nuclease member of the FAN club |
Q42423547 | A novel single-stranded DNA-specific 3'-5' exonuclease, Thermus thermophilus exonuclease I, is involved in several DNA repair pathways |
Q36540457 | A personal historical view of DNA mismatch repair with an emphasis on eukaryotic DNA mismatch repair |
Q37181822 | A possible mechanism for exonuclease 1-independent eukaryotic mismatch repair |
Q28534685 | A reversible histone H3 acetylation cooperates with mismatch repair and replicative polymerases in maintaining genome stability |
Q36173942 | AIDing antibody diversity by error-prone mismatch repair |
Q36229211 | APE1- and APE2-dependent DNA breaks in immunoglobulin class switch recombination. |
Q36457060 | ATR-dependent pathways control hEXO1 stability in response to stalled forks. |
Q37068086 | Acetylation regulates DNA repair mechanisms in human cells |
Q104079557 | Acquired somatic MMR deficiency is a major cause of MSI tumor in patients suspected for "Lynch-like syndrome" including young patients |
Q35690218 | Activation of Saccharomyces cerevisiae Mlh1-Pms1 Endonuclease in a Reconstituted Mismatch Repair System |
Q33506407 | Adenosine triphosphate stimulates Aquifex aeolicus MutL endonuclease activity |
Q36614680 | An intact Pms2 ATPase domain is not essential for male fertility |
Q34904714 | Analysis of the interaction interfaces of the N-terminal domain from Pseudomonas aeruginosa MutL |
Q36540495 | Antibody diversification caused by disrupted mismatch repair and promiscuous DNA polymerases |
Q27024636 | Antimutator variants of DNA polymerases |
Q34088809 | Application of molecular diagnostics for the detection of Lynch syndrome |
Q36759880 | Apurinic/apyrimidinic endonuclease 1 is the essential nuclease during immunoglobulin class switch recombination |
Q28383743 | Arsenic Inhibits DNA Mismatch Repair by Promoting EGFR Expression and PCNA Phosphorylation. |
Q36215937 | Assessment of anti-recombination and double-strand break-induced gene conversion in human cells by a chromosomal reporter |
Q47121039 | Autophagy Roles in the Modulation of DNA Repair Pathways. |
Q36597002 | Beta clamp directs localization of mismatch repair in Bacillus subtilis |
Q33726437 | Bi-directional routing of DNA mismatch repair protein human exonuclease 1 to replication foci and DNA double strand breaks |
Q64114352 | Binding of the regulatory domain of MutL to the sliding β-clamp is species specific |
Q35880032 | Biochemical analysis of the human mismatch repair proteins hMutSα MSH2(G674A)-MSH6 and MSH2-MSH6(T1219D) |
Q33604620 | Biochemistry of Meiotic Recombination: Formation, Processing, and Resolution of Recombination Intermediates |
Q30502502 | Body mass index in early adulthood and colorectal cancer risk for carriers and non-carriers of germline mutations in DNA mismatch repair genes |
Q46726051 | Bound nucleotide controls the endonuclease activity of mismatch repair enzyme MutL. |
Q26827700 | Breaking bad: The mutagenic effect of DNA repair |
Q34582950 | CAF-I-dependent control of degradation of the discontinuous strands during mismatch repair |
Q42518081 | CRT1 is a nuclear-translocated MORC endonuclease that participates in multiple levels of plant immunity |
Q37302747 | Catalog of mRNA expression patterns for DNA methylating and demethylating genes in developing mouse lower urinary tract |
Q27026386 | Causal link between microsatellite instability and hMRE11 dysfunction in human cancers |
Q43453364 | Celebrating the work of Nobel Laureate Paul Modrich |
Q37109595 | Cell-surface markers for colon adenoma and adenocarcinoma |
Q85228405 | Characterization of C- and N-terminal domains of Aquifex aeolicus MutL endonuclease: N-terminal domain stimulates the endonuclease activity of C-terminal domain in a zinc-dependent manner |
Q37072156 | Characterization of a highly conserved binding site of Mlh1 required for exonuclease I-dependent mismatch repair |
Q35085004 | Characterization of the endonuclease and ATP-dependent flap endo/exonuclease of Dna2. |
Q28277364 | Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2 |
Q35865056 | Chimeric Saccharomyces cerevisiae Msh6 protein with an Msh3 mispair-binding domain combines properties of both proteins. |
Q35910253 | Chromosomal directionality of DNA mismatch repair in Escherichia coli |
Q42556770 | Chromosome fragility at GAA tracts in yeast depends on repeat orientation and requires mismatch repair |
Q42424836 | Clamping down on mismatches |
Q36914870 | Class switch recombination efficiency and junction microhomology patterns in Msh2-, Mlh1-, and Exo1-deficient mice depend on the presence of mu switch region tandem repeats |
Q95309234 | Combinatorial approach of in silico and in vitro evaluation of MLH1 variant associated with lynch syndrome like metastatic colorectal cancer |
Q35648724 | Comparative transcriptomic analysis revealed adaptation mechanism of Phrynocephalus erythrurus, the highest altitude Lizard living in the Qinghai-Tibet Plateau |
Q34958445 | Complex regulation and function of activation-induced cytidine deaminase |
Q40806587 | Concerted action of the MutLβ heterodimer and Mer3 helicase regulates the global extent of meiotic gene conversion. |
Q34809944 | Constitutional mismatch repair-deficiency syndrome: have we so far seen only the tip of an iceberg? |
Q39109267 | Control of Genome Integrity by RFC Complexes; Conductors of PCNA Loading onto and Unloading from Chromatin during DNA Replication |
Q57784307 | Coordinating Multi-Protein Mismatch Repair by Managing Diffusion Mechanics on the DNA |
Q37088805 | Cost of rNTP/dNTP pool imbalance at the replication fork |
Q35928818 | Coupling distant sites in DNA during DNA mismatch repair. |
Q97518601 | Cyclin N-Terminal Domain-Containing-1 Coordinates Meiotic Crossover Formation with Cell-Cycle Progression in a Cyclin-Independent Manner |
Q64388100 | DNA Breaks in Ig V Regions Are Predominantly Single Stranded and Are Generated by UNG and MSH6 DNA Repair Pathways |
Q92368872 | DNA Damage and Associated DNA Repair Defects in Disease and Premature Aging |
Q34509028 | DNA Mismatch Repair |
Q36884849 | DNA Mismatch Repair Interacts with CAF-1- and ASF1A-H3-H4-dependent Histone (H3-H4)2 Tetramer Deposition |
Q37602208 | DNA mismatch repair (MMR)-dependent 5-fluorouracil cytotoxicity and the potential for new therapeutic targets. |
Q28291067 | DNA mismatch repair in eukaryotes and bacteria |
Q45979692 | DNA mismatch repair in trinucleotide repeat instability. |
Q24647002 | DNA mismatch repair: molecular mechanism, cancer, and ageing |
Q26822699 | DNA polymerase ε and its roles in genome stability |
Q37724828 | DNA polymerases β and λ do not directly affect Ig variable region somatic hypermutation although their absence reduces the frequency of mutations |
Q36194928 | DNA repair and genome maintenance in Bacillus subtilis |
Q28709604 | DNA repair mechanisms and the bypass of DNA damage in Saccharomyces cerevisiae |
Q28295863 | DNA replication fidelity and cancer |
Q26996542 | DNA triplet repeat expansion and mismatch repair |
Q28264475 | Delineation of joint molecule resolution pathways in meiosis identifies a crossover-specific resolvase |
Q89529831 | Detection of Germline Mutations in Breast Cancer Patients with Clinical Features of Hereditary Cancer Syndrome Using a Multi-Gene Panel Test |
Q34196484 | Detection of heterozygous mutations in the genome of mismatch repair defective diploid yeast using a Bayesian approach |
Q39581441 | Determining the functional significance of mismatch repair gene missense variants using biochemical and cellular assays |
Q33645614 | Direct visualization of asymmetric adenine-nucleotide-induced conformational changes in MutL alpha |
Q37209783 | Discovery of novel non-synonymous SNP variants in 988 candidate genes from 6 centenarians by target capture and next-generation sequencing |
Q34513843 | Dissecting endonuclease and exonuclease activities in endonuclease V from Thermotoga maritima |
Q36670109 | Distinct effects of the recurrent Mlh1G67R mutation on MMR functions, cancer, and meiosis |
Q40895728 | Distinct regulation of Mlh1p heterodimers in meiosis and mitosis in Saccharomyces cerevisiae. |
Q45962906 | DnaN clamp zones provide a platform for spatiotemporal coupling of mismatch detection to DNA replication. |
Q28534756 | Dominant mutations in S. cerevisiae PMS1 identify the Mlh1-Pms1 endonuclease active site and an exonuclease 1-independent mismatch repair pathway |
Q37210972 | Dual daughter strand incision is processive and increases the efficiency of DNA mismatch repair |
Q36742733 | Dynamic control of strand excision during human DNA mismatch repair |
Q33561045 | Embryonic lethality after combined inactivation of Fancd2 and Mlh1 in mice |
Q38556007 | Emergence and evolutionary analysis of the human DDR network: implications in comparative genomics and downstream analyses |
Q36643853 | Emergence of DNA polymerase ε antimutators that escape error-induced extinction in yeast |
Q36764079 | Endonuclease activities of MutLα and its homologs in DNA mismatch repair |
Q89179272 | Endonuclease-independent DNA mismatch repair processes on the lagging strand |
Q37438949 | Epigenetic Enhancement of the Post-replicative DNA Mismatch Repair of Mammalian Genomes by a Hemi-(m)CpG-Np95-Dnmt1 Axis |
Q33886303 | Epistatic roles for Pseudomonas aeruginosa MutS and DinB (DNA Pol IV) in coping with reactive oxygen species-induced DNA damage |
Q33711830 | Eukaryotic Mismatch Repair in Relation to DNA Replication |
Q88009101 | Evaluation of MLH1 variants of unclear significance |
Q39712247 | Evidence for ATP-dependent structural rearrangement of nuclease catalytic site in DNA mismatch repair endonuclease MutL. |
Q36115776 | Evidence that the DNA mismatch repair system removes 1-nucleotide Okazaki fragment flaps |
Q38255035 | Evolution of the methyl directed mismatch repair system in Escherichia coli. |
Q35600545 | Excision of translesion synthesis errors orchestrates responses to helix-distorting DNA lesions |
Q38974172 | Exo1 independent DNA mismatch repair involves multiple compensatory nucleases |
Q36553485 | Exonuclease 1 preferentially repairs mismatches generated by DNA polymerase α |
Q28261787 | Exonuclease 1-dependent and independent mismatch repair |
Q37049546 | Extrahelical (CAG)/(CTG) triplet repeat elements support proliferating cell nuclear antigen loading and MutLα endonuclease activation |
Q37870047 | FANCP/SLX4: a Swiss army knife of DNA interstrand crosslink repair |
Q58778385 | Fluorescence detection of DNA mismatch repair in human cells |
Q89793100 | Functional Characterization of a Missense Variant of MLH1 Identified in Lynch Syndrome Pedigree |
Q38685097 | Functional analysis of rare variants in mismatch repair proteins augments results from computation-based predictive methods |
Q42833087 | Functional characterization of MLH1 missense variants identified in Lynch syndrome patients. |
Q27659620 | Functional residues on the surface of the N-terminal domain of yeast Pms1 |
Q34478988 | Functional role of DNA mismatch repair gene PMS2 in prostate cancer cells. |
Q33465403 | Functions of MutLalpha, replication protein A (RPA), and HMGB1 in 5'-directed mismatch repair |
Q52359109 | GAA•TTC repeat expansion in human cells is mediated by mismatch repair complex MutLγ and depends upon the endonuclease domain in MLH3 isoform one. |
Q27932384 | Genetic analysis of mlh3 mutations reveals interactions between crossover promoting factors during meiosis in baker's yeast |
Q33649978 | Genetic testing for hereditary colorectal cancer |
Q39511907 | Genome Wide In silico Analysis of the Mismatch Repair Components of Plasmodium falciparum and Their Comparison with Human Host |
Q37461159 | Genome dynamics in major bacterial pathogens. |
Q34400791 | Genome-scale transcriptome analysis of the alpine "glasshouse" plant Rheum nobile (Polygonaceae) with special translucent bracts |
Q33836026 | Genomic and epigenetic instability in colorectal cancer pathogenesis |
Q52690553 | H3K36me3-mediated mismatch repair preferentially protects actively transcribed genes from mutation. |
Q37140473 | Hijacked DNA repair proteins and unchained DNA polymerases |
Q36389371 | How DNA-repair proteins find their targets |
Q37452969 | Human CAF-1-dependent nucleosome assembly in a defined system |
Q36328799 | Human DNA mismatch repair: coupling of mismatch recognition to strand-specific excision |
Q47766916 | Human DNA polymerase delta double-mutant D316A;E318A interferes with DNA mismatch repair in vitro |
Q39913958 | Human MutL-complexes monitor homologous recombination independently of mismatch repair |
Q33343475 | Human MutLalpha: the jack of all trades in MMR is also an endonuclease |
Q89517728 | Human MutLγ, the MLH1-MLH3 heterodimer, is an endonuclease that promotes DNA expansion |
Q36946520 | Human PMS2 deficiency is associated with impaired immunoglobulin class switch recombination |
Q36451916 | Human mismatch repair protein hMutLα is required to repair short slipped-DNAs of trinucleotide repeats |
Q36812749 | Human postmeiotic segregation 2 exhibits biased repair at tetranucleotide microsatellite sequences |
Q33791326 | Hydrolytic function of Exo1 in mammalian mismatch repair. |
Q90647988 | Identification of Exo1-Msh2 interaction motifs in DNA mismatch repair and new Msh2-binding partners |
Q36741556 | Identification of regulatory factor X as a novel mismatch repair stimulatory factor |
Q36935372 | Identification of two conserved aspartic acid residues required for DNA digestion by a novel thermophilic Exonuclease VII in Thermotoga maritima |
Q27001131 | IgH chain class switch recombination: mechanism and regulation |
Q36633302 | Immunoglobulin class-switch recombination deficiencies |
Q39514722 | Immunohistochemistry versus microsatellite instability testing for screening colorectal cancer patients at risk for hereditary nonpolyposis colorectal cancer syndrome. Part I. The utility of immunohistochemistry |
Q37115245 | Improvement of ENU Mutagenesis Efficiency Using Serial Injection and Mismatch Repair Deficiency Mice |
Q33892504 | Inactivation of the DNA repair genes mutS, mutL or the anti-recombination gene mutS2 leads to activation of vitamin B1 biosynthesis genes |
Q35451422 | Influence of oxidized purine processing on strand directionality of mismatch repair |
Q37778043 | Inherited Defects of Immunoglobulin Class Switch Recombination |
Q39991083 | Inhibition of the 5' to 3' exonuclease activity of hEXO1 by 8-oxoguanine |
Q38773809 | Inserting Extrahelical Structures into Long DNA Substrates for Single-Molecule Studies of DNA Mismatch Repair. |
Q33812133 | Interaction between human mismatch repair recognition proteins and checkpoint sensor Rad9-Rad1-Hus1 |
Q33719300 | Interaction of proliferating cell nuclear antigen with PMS2 is required for MutLα activation and function in mismatch repair. |
Q33648599 | Interactions of human mismatch repair proteins MutSalpha and MutLalpha with proteins of the ATR-Chk1 pathway |
Q37138006 | Interference of mismatch and base excision repair during the processing of adjacent U/G mispairs may play a key role in somatic hypermutation |
Q90429771 | Intrinsically disordered regions regulate both catalytic and non-catalytic activities of the MutLα mismatch repair complex |
Q38796195 | Invited review: Architectures and mechanisms of ATP binding cassette proteins |
Q47135454 | Involvement of DNA mismatch repair in the maintenance of heterochromatic DNA stability in Saccharomyces cerevisiae. |
Q33653935 | Lynch syndrome among gynecologic oncology patients meeting Bethesda guidelines for screening |
Q38084166 | Lynch syndrome-associated neoplasms: a discussion on histopathology and immunohistochemistry. |
Q50287467 | MLH1:PMS2 makes single strand incision near insertion/deletion loop of 2 bases or more |
Q50287455 | MLH1:PMS2 makes single strand incision near 1-2 base mismatch |
Q34764888 | Mechanism and regulation of class switch recombination |
Q28262719 | Mechanisms and functions of DNA mismatch repair |
Q37540260 | Mechanisms in E. coli and Human Mismatch Repair (Nobel Lecture). |
Q36564560 | Mechanisms in eukaryotic mismatch repair |
Q39293345 | Mechanisms of DNA damage, repair, and mutagenesis |
Q83835402 | Microsatellite instability in colorectal cancer: from molecular oncogenic mechanisms to clinical implications |
Q64882642 | Microsatellite instability in metaplasia-dysplasia-adenocarcinoma sequence of Barrett esophagus: a retrospective study. |
Q43864989 | Milestones of Lynch syndrome: 1895-2015. |
Q38044810 | Minimizing the damage: repair pathways keep mitochondrial DNA intact |
Q97526961 | Mismatch Repair Pathway, Genome Stability and Cancer |
Q38254881 | Mismatch binding, ADP-ATP exchange and intramolecular signaling during mismatch repair |
Q41849601 | Mismatch correction modulates mutation frequency and pilus phase and antigenic variation in Neisseria gonorrhoeae |
Q36283640 | Mismatch repair |
Q34660590 | Mismatch repair causes the dynamic release of an essential DNA polymerase from the replication fork |
Q38170877 | Mismatch repair deficiency in ovarian cancer -- molecular characteristics and clinical implications |
Q52678656 | Mismatch repair deficiency is associated with MSI phenotype, increased tumor-infiltrating lymphocytes and PD-L1 expression in immune cells in ovarian cancer. |
Q35164333 | Mismatch repair during homologous and homeologous recombination |
Q35034398 | Mismatch repair genes Mlh1 and Mlh3 modify CAG instability in Huntington's disease mice: genome-wide and candidate approaches |
Q34773522 | Mismatch repair proteins MSH2, MLH1, and EXO1 are important for class-switch recombination events occurring in B cells that lack nonhomologous end joining |
Q58790068 | Mismatch repair-based stratification for immune checkpoint blockade therapy |
Q35605313 | Mismatch-mediated error prone repair at the immunoglobulin genes |
Q34723491 | Mismatch-repair protein MSH6 is associated with Ku70 and regulates DNA double-strand break repair |
Q37691675 | Mispair-specific recruitment of the Mlh1-Pms1 complex identifies repair substrates of the Saccharomyces cerevisiae Msh2-Msh3 complex |
Q28305501 | Mlh1-Mlh3, a meiotic crossover and DNA mismatch repair factor, is a Msh2-Msh3-stimulated endonuclease |
Q35165645 | Mlh2 is an accessory factor for DNA mismatch repair in Saccharomyces cerevisiae |
Q38168515 | Modern aspects of the structural and functional organization of the DNA mismatch repair system |
Q36009224 | Modulation of microRNA processing by mismatch repair protein MutLα. |
Q37483304 | Modulation of mutagenesis in eukaryotes by DNA replication fork dynamics and quality of nucleotide pools |
Q24630140 | Molecular mechanisms of the whole DNA repair system: a comparison of bacterial and eukaryotic systems |
Q33324168 | MutL homologs in restriction-modification systems and the origin of eukaryotic MORC ATPases |
Q91404367 | MutL sliding clamps coordinate exonuclease-independent Escherichia coli mismatch repair |
Q36055693 | MutL traps MutS at a DNA mismatch |
Q33799870 | MutLalpha and proliferating cell nuclear antigen share binding sites on MutSbeta |
Q64260996 | MutS Modulates RecA-Mediated DNA Strand Exchange Between Divergent DNA Sequences |
Q50989071 | MutS stimulates the endonuclease activity of MutL in an ATP-hydrolysis-dependent manner. |
Q42409924 | MutS/MutL crystal structure reveals that the MutS sliding clamp loads MutL onto DNA. |
Q39612088 | MutSα maintains the mismatch repair capability by inhibiting PCNA unloading. |
Q52720227 | Mutational signatures of DNA mismatch repair deficiency in C. elegans and human cancers. |
Q24646969 | Mutations affecting a putative MutLalpha endonuclease motif impact multiple mismatch repair functions |
Q35537125 | Mutations in the MutSalpha interaction interface of MLH1 can abolish DNA mismatch repair |
Q28539398 | NMR characterization of the interaction of the endonuclease domain of MutL with divalent metal ions and ATP |
Q27011117 | New insights and challenges in mismatch repair: getting over the chromatin hurdle |
Q28084645 | New insights into the mechanism of DNA mismatch repair |
Q36775503 | Non-canonical uracil processing in DNA gives rise to double-strand breaks and deletions: relevance to class switch recombination |
Q35829272 | Nuclear localization of human DNA mismatch repair protein exonuclease 1 (hEXO1) |
Q37790458 | Nucleases: diversity of structure, function and mechanism. |
Q57009219 | Nucleosomes around a mismatched base pair are excluded via an Msh2-dependent reaction with the aid of SNF2 family ATPase Smarcad1 |
Q37037194 | O6-methylguanine-induced cell death involves exonuclease 1 as well as DNA mismatch recognition in vivo |
Q34030005 | PARP-1 enhances the mismatch-dependence of 5'-directed excision in human mismatch repair in vitro |
Q98567982 | PCNA activates the MutLγ endonuclease to promote meiotic crossing over |
Q33961620 | PCNA and Msh2-Msh6 activate an Mlh1-Pms1 endonuclease pathway required for Exo1-independent mismatch repair. |
Q34151839 | PCNA and MutLα: partners in crime in triplet repeat expansion? |
Q24606670 | PCNA function in the activation and strand direction of MutLα endonuclease in mismatch repair |
Q53317052 | PMS1 from Arabidopsis thaliana: optimization of protein overexpression in Escherichia coli. |
Q34068165 | PMS2 endonuclease activity has distinct biological functions and is essential for genome maintenance |
Q38029584 | Pathological assessment of mismatch repair gene variants in Lynch syndrome: past, present, and future |
Q33834760 | Pathways to meiotic recombination in Arabidopsis thaliana |
Q83224650 | Perturbation of base excision repair sensitizes breast cancer cells to APOBEC3 deaminase-mediated mutations |
Q36933187 | Phage-associated mutator phenotype in group A streptococcus |
Q35590357 | Phosphorylation of PCNA by EGFR inhibits mismatch repair and promotes misincorporation during DNA synthesis |
Q92282100 | Phosphorylation of proliferating cell nuclear antigen promotes cancer progression by activating the ATM/Akt/GSK3β/Snail signaling pathway |
Q24338232 | Physical and functional interactions between Werner syndrome helicase and mismatch-repair initiation factors |
Q41984058 | Pms2 and uracil-DNA glycosylases act jointly in the mismatch repair pathway to generate Ig gene mutations at A-T base pairs. |
Q28506086 | Pms2 suppresses large expansions of the (GAA·TTC)n sequence in neuronal tissues |
Q27690911 | Postreplicative mismatch repair |
Q34025948 | Processing of joint molecule intermediates by structure-selective endonucleases during homologous recombination in eukaryotes |
Q37821231 | Progress and prospects: oligonucleotide-directed gene modification in mouse embryonic stem cells: a route to therapeutic application. |
Q30397641 | Proliferating cell nuclear antigen (PCNA): a key factor in DNA replication and cell cycle regulation |
Q35879662 | Protein roadblocks and helix discontinuities are barriers to the initiation of mismatch repair |
Q42911480 | Proteomic Analysis Reveals a Novel Mutator S (MutS) Partner Involved in Mismatch Repair Pathway. |
Q33557562 | Proximity to AGCT sequences dictates MMR-independent versus MMR-dependent mechanisms for AID-induced mutation via UNG2. |
Q38005951 | Recognition of damaged DNA: structure and dynamic markers |
Q33556873 | Reconstitution of Saccharomyces cerevisiae DNA polymerase ε-dependent mismatch repair with purified proteins |
Q37327269 | Reduced ATR or Chk1 expression leads to chromosome instability and chemosensitization of mismatch repair-deficient colorectal cancer cells |
Q36540486 | Regulation of mismatch repair by histone code and posttranslational modifications in eukaryotic cells |
Q98568696 | Regulation of the MLH1-MLH3 endonuclease in meiosis |
Q34420649 | Repair of naturally occurring mismatches can induce mutations in flanking DNA. |
Q28258327 | Replicative DNA polymerase δ but not ε proofreads errors in Cis and in Trans |
Q36276354 | Residues in the N-terminal domain of MutL required for mismatch repair in Bacillus subtilis |
Q42695853 | Retention of Core Meiotic Genes Across Diverse Hymenoptera |
Q28689053 | Ribonucleotides are signals for mismatch repair of leading-strand replication errors |
Q24338799 | Ribonucleotides misincorporated into DNA act as strand-discrimination signals in eukaryotic mismatch repair |
Q27938184 | Role of proliferating cell nuclear antigen interactions in the mismatch repair-dependent processing of mitotic and meiotic recombination intermediates in yeast |
Q36540776 | Roles for mismatch repair family proteins in promoting meiotic crossing over |
Q36549257 | Saccharomyces cerevisiae MutLalpha is a mismatch repair endonuclease |
Q33667306 | Schizosaccharomyces pombe MutSα and MutLα Maintain Stability of Tetra-Nucleotide Repeats and Msh3 of Hepta-Nucleotide Repeats |
Q35027619 | Single molecule studies of DNA mismatch repair |
Q39237485 | Single-Molecule FRET to Measure Conformational Dynamics of DNA Mismatch Repair Proteins |
Q30528236 | Single-molecule imaging reveals target-search mechanisms during DNA mismatch repair |
Q36394407 | Single-molecule motions and interactions in live cells reveal target search dynamics in mismatch repair. |
Q26999680 | Single-molecule views of MutS on mismatched DNA. |
Q41159830 | Small-angle X-ray scattering analysis reveals the ATP-bound monomeric state of the ATPase domain from the homodimeric MutL endonuclease, a GHKL phosphotransferase superfamily protein |
Q39148893 | Stable expression of MutLγ in human cells reveals no specific response to mismatched DNA, but distinct recruitment to damage sites. |
Q57784305 | Stochastic Processes and Component Plasticity Governing DNA Mismatch Repair |
Q41045652 | Structural Features and Functional Dependency on β-Clamp Define Distinct Subfamilies of Bacterial Mismatch Repair Endonuclease MutL |
Q28285134 | Structural, molecular and cellular functions of MSH2 and MSH6 during DNA mismatch repair, damage signaling and other noncanonical activities |
Q27684073 | Structure of the MutLα C-terminal domain reveals how Mlh1 contributes to Pms1 endonuclease site |
Q27663136 | Structure of the endonuclease domain of MutL: unlicensed to cut. |
Q35927768 | Structure of the human MLH1 N-terminus: implications for predisposition to Lynch syndrome |
Q34121605 | Synchronous gastric and sebaceous cancers, a rare manifestation of MLH1-related Muir-Torre syndrome |
Q31136996 | Targeting DNA Mismatches with Rhodium Metalloinsertors |
Q28301386 | Temporally and biochemically distinct activities of Exo1 during meiosis: double-strand break resection and resolution of double Holliday junctions |
Q27665705 | The C-Terminal Domain of the MutL Homolog from Neisseria gonorrhoeae Forms an Inverted Homodimer |
Q43814300 | The C-terminal domain is sufficient for endonuclease activity of Neisseria gonorrhoeae MutL. |
Q48332104 | The Changing Landscape of Lynch Syndrome due to PMS2 Mutations. |
Q40222264 | The E705K mutation in hPMS2 exerts recessive, not dominant, effects on mismatch repair |
Q28551589 | The Eukaryotic Mismatch Recognition Complexes Track with the Replisome during DNA Synthesis |
Q43189001 | The G67E mutation in hMLH1 is associated with an unusual presentation of Lynch syndrome |
Q36627936 | The Kub5-Hera/RPRD1B interactome: a novel role in preserving genetic stability by regulating DNA mismatch repair |
Q51312086 | The Major Replicative Histone Chaperone CAF-1 Suppresses the Activity of the DNA Mismatch Repair System in the Cytotoxic Response to a DNA-methylating Agent. |
Q36961147 | The Many Roles of PCNA in Eukaryotic DNA Replication |
Q24657814 | The MutSalpha-proliferating cell nuclear antigen interaction in human DNA mismatch repair |
Q28306188 | The Saccharomyces cerevisiae Mlh1-Mlh3 heterodimer is an endonuclease that preferentially binds to Holliday junctions |
Q33351069 | The ancestral role of ATP hydrolysis in type II topoisomerases: prevention of DNA double-strand breaks |
Q33762979 | The biochemical basis of microsatellite instability and abnormal immunohistochemistry and clinical behavior in Lynch syndrome: from bench to bedside |
Q24655454 | The clinical phenotype of Lynch syndrome due to germ-line PMS2 mutations |
Q37334051 | The concerted action of Msh2 and UNG stimulates somatic hypermutation at A . T base pairs |
Q26770149 | The conserved molecular machinery in DNA mismatch repair enzyme structures |
Q38246275 | The dual nature of mismatch repair as antimutator and mutator: for better or for worse |
Q41860625 | The effects of nucleotides on MutS-DNA binding kinetics clarify the role of MutS ATPase activity in mismatch repair |
Q34528290 | The endonuclease domain of MutL interacts with the β sliding clamp |
Q61313168 | The first functional study of MLH3 mutations found in cancer patients |
Q37172151 | The genomics of colorectal cancer: state of the art. |
Q34533276 | The mechanism of mismatch repair and the functional analysis of mismatch repair defects in Lynch syndrome |
Q33615733 | The mismatch repair and meiotic recombination endonuclease Mlh1-Mlh3 is activated by polymer formation and can cleave DNA substrates in trans. |
Q64986474 | The mutagen and carcinogen cadmium is a high-affinity inhibitor of the zinc-dependent MutLα endonuclease. |
Q91595501 | The properties of Msh2-Msh6 ATP binding mutants suggest a signal amplification mechanism in DNA mismatch repair |
Q36370907 | The sliding clamp tethers the endonuclease domain of MutL to DNA |
Q36162012 | The unstructured linker arms of Mlh1-Pms1 are important for interactions with DNA during mismatch repair |
Q90622154 | The unstructured linker arms of MutL enable GATC site incision beyond roadblocks during initiation of DNA mismatch repair |
Q38940317 | Understanding how mismatch repair proteins participate in the repair/anti-recombination decision |
Q36740600 | Unique and important consequences of RECQ1 deficiency in mammalian cells |
Q44873571 | Using Atomic Force Microscopy to Characterize the Conformational Properties of Proteins and Protein-DNA Complexes That Carry Out DNA Repair. |
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