YB-1 disrupts mismatch repair complex formation, interferes with MutSα recruitment on mismatch and inhibits mismatch repair through interacting with PCNA.

scientific article published on 21 October 2013

YB-1 disrupts mismatch repair complex formation, interferes with MutSα recruitment on mismatch and inhibits mismatch repair through interacting with PCNA. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/ONC.2013.450
P8608Fatcat IDrelease_65hfowtzfzcqflormdtgjyfe2e
P698PubMed publication ID24141788

P50authorWoei-Horng FangQ59698735
P2093author name stringY-H Wu Lee
C-C Lin
Y-W Chang
C-C Chiu
R-T Mai
P2860cites workFunctional interaction of proliferating cell nuclear antigen with MSH2-MSH6 and MSH2-MSH3 complexesQ24290314
Human exonuclease I is required for 5' and 3' mismatch repairQ24292224
A defined human system that supports bidirectional mismatch-provoked excisionQ24298110
Interaction of human thymidine kinase 1 with p21(Waf1)Q24532825
PCNA function in the activation and strand direction of MutLα endonuclease in mismatch repairQ24606670
An internal EELD domain facilitates mitochondrial targeting of Mcl-1 via a Tom70-dependent pathwayQ24670136
PCNA-MutSalpha-mediated binding of MutLalpha to replicative DNA with mismatched bases to induce apoptosis in human cellsQ24814841
Evidence for involvement of yeast proliferating cell nuclear antigen in DNA mismatch repairQ27938608
Requirement for PCNA in DNA mismatch repair at a step preceding DNA resynthesisQ27939891
Regulation of apoptosis and cell cycle progression by MCL1. Differential role of proliferating cell nuclear antigenQ28138082
Proliferating cell nuclear antigen and Msh2p-Msh6p interact to form an active mispair recognition complexQ28142999
Nuclear translocation of mismatch repair proteins MSH2 and MSH6 as a response of cells to alkylating agentsQ28144364
Carcinogenesis and microsatellite instability: the interrelationship between genetics and epigeneticsQ28253670
DNA mismatch repairQ28256190
Nuclear translocation of the Y-box binding protein by ultraviolet irradiationQ28257567
Mechanisms and functions of DNA mismatch repairQ28262719
Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancerQ28294774
DNA mismatch repair: functions and mechanismsQ28296096
PCNA, the maestro of the replication forkQ28303101
A small peptide inhibitor of DNA replication defines the site of interaction between the cyclin-dependent kinase inhibitor p21WAF1 and proliferating cell nuclear antigenQ28303106
ATP-dependent interaction of human mismatch repair proteins and dual role of PCNA in mismatch repairQ28610858
Reconstitution of 5'-directed human mismatch repair in a purified systemQ33222844
Human mismatch repair: reconstitution of a nick-directed bidirectional reactionQ33224078
Mismatch Repair proteins are recruited to replicating DNA through interaction with Proliferating Cell Nuclear Antigen (PCNA)Q33305049
A human 200-kDa protein binds selectively to DNA fragments containing G.T mismatchesQ33676586
Strand-specific mismatch correction in nuclear extracts of human and Drosophila melanogaster cell linesQ33720790
Bi-directional routing of DNA mismatch repair protein human exonuclease 1 to replication foci and DNA double strand breaksQ33726437
MutLalpha and proliferating cell nuclear antigen share binding sites on MutSbetaQ33799870
YB-1 is important for late-stage embryonic development, optimal cellular stress responses, and the prevention of premature senescenceQ33837101
DNA ligase I is recruited to sites of DNA replication by an interaction with proliferating cell nuclear antigen: identification of a common targeting mechanism for the assembly of replication factoriesQ33889077
Unmasking a killer: DNA O(6)-methylguanine and the cytotoxicity of methylating agentsQ33892805
Prognostic association of YB-1 expression in breast cancers: a matter of antibody.Q33939605
Structure-function relationships of Na(+), K(+), ATP, or Mg(2+) binding and energy transduction in Na,K-ATPase.Q34180462
MGMT: key node in the battle against genotoxicity, carcinogenicity and apoptosis induced by alkylating agentsQ34626127
N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) triggers MSH2 and Cdt2 protein-dependent degradation of the cell cycle and mismatch repair (MMR) inhibitor protein p21Waf1/Cip1Q35313485
Mismatch repair and DNA damage signallingQ35848516
The N terminus of Saccharomyces cerevisiae Msh6 is an unstructured tether to PCNAQ36026779
Signalling cell cycle arrest and cell death through the MMR SystemQ36333085
An alkylation-tolerant, mutator human cell line is deficient in strand-specific mismatch repair.Q36412005
The multifaceted mismatch-repair systemQ36448284
Y-box binding protein 1: providing a new angle on translational regulationQ36487359
Mechanisms in eukaryotic mismatch repairQ36564560
Chemotherapeutic agents for colorectal cancer with a defective mismatch repair system: the state of the art.Q36630370
Balancing repair and tolerance of DNA damage caused by alkylating agentsQ36651488
Mechanisms of chemoresistance to alkylating agents in malignant gliomaQ36726010
Role of mismatch repair and MGMT in response to anticancer therapiesQ37160587
Novel DNA mismatch-repair activity involving YB-1 in human mitochondriaQ37219476
Significance of the Y-box proteins in human cancersQ37241863
DNA Repair in mammalian cells: Mismatched repair: variations on a themeQ37372520
Human MutSalpha recognizes damaged DNA base pairs containing O6-methylguanine, O4-methylthymine, or the cisplatin-d(GpG) adductQ37522716
Genomic instability of surgical sample and cancer-initiating cell lines from human glioblastoma.Q37971573
Y-box-binding protein 1 (YB-1) and its functionsQ37984603
Mismatch repair deficient human cells: spontaneous and MNNG-induced mutational spectra in the HPRT geneQ38311693
Defective mismatch binding and a mutator phenotype in cells tolerant to DNA damageQ38320078
Biochemical characterization of the interaction between the Saccharomyces cerevisiae MSH2-MSH6 complex and mispaired bases in DNA.Q38320783
hMSH2 and hMSH6 play distinct roles in mismatch binding and contribute differently to the ATPase activity of hMutSalphaQ38336441
Hepatitis C virus core protein recruits nucleolar phosphoprotein B23 and coactivator p300 to relieve the repression effect of transcriptional factor YY1 on B23 gene expressionQ39361807
Saccharomyces cerevisiae pol30 (proliferating cell nuclear antigen) mutations impair replication fidelity and mismatch repairQ39449001
Inhibition of Y-box binding protein-1 slows the growth of glioblastoma multiforme and sensitizes to temozolomide independent O6-methylguanine-DNA methyltransferaseQ39765532
Translational activation of snail1 and other developmentally regulated transcription factors by YB-1 promotes an epithelial-mesenchymal transitionQ39857546
BCR/ABL inhibits mismatch repair to protect from apoptosis and induce point mutationsQ39991847
Molecular testing for microsatellite instability and DNA mismatch repair defects in hereditary and sporadic colorectal cancers--ready for prime time?Q40160267
BCR/ABL kinase induces self-mutagenesis via reactive oxygen species to encode imatinib resistanceQ40306743
YB-1 promotes strand separation in vitro of duplex DNA containing either mispaired bases or cisplatin modifications, exhibits endonucleolytic activities and binds several DNA repair proteinsQ40600190
Mechanisms of tolerance to DNA damaging therapeutic drugsQ43829355
Transfer of the MSH2.MSH6 complex from proliferating cell nuclear antigen to mispaired bases in DNA.Q44219222
Differential requirement for proliferating cell nuclear antigen in 5' and 3' nick-directed excision in human mismatch repairQ44761854
Interaction of nick-directed DNA mismatch repair and loop repair in human cellsQ47581991
Molecular profiling identifies prognostic subgroups of pediatric glioblastoma and shows increased YB-1 expression in tumors.Q48221611
Endonucleolytic function of MutLalpha in human mismatch repairQ50335575
Expression of Y-Box-binding protein 1 in Chinese patients with breast cancer.Q53280838
Nuclear expression of Y-box-binding protein-1 correlates with P-glycoprotein and topoisomerase II alpha expression, and with poor prognosis in synovial sarcoma.Q53944272
Molecular mechanisms associated with chromosomal and microsatellite instability in sporadic glioblastoma multiforme.Q55471962
Nuclear localization and increased levels of transcription factor YB-1 in primary human breast cancers are associated with intrinsic MDR1 gene expressionQ56029438
Analysis of interactions between mismatch repair initiation factors and the replication processivity factor PCNAQ81515485
P433issue43
P407language of work or nameEnglishQ1860
P921main subjectDNA mismatch repairQ2984243
P304page(s)5065-5077
P577publication date2013-10-21
P1433published inOncogeneQ1568657
P1476titleYB-1 disrupts mismatch repair complex formation, interferes with MutSα recruitment on mismatch and inhibits mismatch repair through interacting with PCNA
P478volume33

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cites work (P2860)
Q41199595DDX54 regulates transcriptome dynamics during DNA damage response
Q50895098Disrupting Y-Box-Binding Protein 1 Function Using OSU-03012 Prevents Endometriosis Progression in In Vitro and In Vivo Models
Q64953229Dual Targeting of Y-Box Binding Protein-1 and Akt Inhibits Proliferation and Enhances the Chemosensitivity of Colorectal Cancer Cells.
Q35395549New paradigms in the repair of oxidative damage in human genome: mechanisms ensuring repair of mutagenic base lesions during replication and involvement of accessory proteins.
Q39394137RNA Binding Proteins and Genome Integrity
Q39069088RSK-mediated nuclear accumulation of the cold-shock Y-box protein-1 controls proliferation of T cells and T-ALL blasts
Q26777046The RNA Splicing Response to DNA Damage
Q38450793The interplay between DNA damage response and RNA processing: the unexpected role of splicing factors as gatekeepers of genome stability
Q38780013Up regulation and nuclear translocation of Y-box binding protein 1 (YB-1) is linked to poor prognosis in ERG-negative prostate cancer
Q36281839Y-Box Binding Protein 1 Stabilizes Hepatitis C Virus NS5A via Phosphorylation-Mediated Interaction with NS5A To Regulate Viral Propagation.

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