| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2016PLoSO..1152097W |
| P356 | DOI | 10.1371/JOURNAL.PONE.0152097 |
| P3181 | OpenCitations bibliographic resource ID | 283485 |
| P932 | PMC publication ID | 4806913 |
| P698 | PubMed publication ID | 27011261 |
| P2093 | author name string | Li Chen | |
| Ming Zhang | |||
| Grant M Hatch | |||
| Yang Yu | |||
| Xin Yan | |||
| Fan Yao | |||
| Shengnan Wei | |||
| Xiaoxin Lan | |||
| P2860 | cites work | MicroRNA-370 controls the expression of microRNA-122 and Cpt1alpha and affects lipid metabolism | Q24629354 |
| The maturity-onset diabetes of the young (MODY1) transcription factor HNF4α regulates expression of genes required for glucose transport and metabolism | Q24654815 | ||
| Effects of pharmacological treatments on micro- and macrovascular complications of type 2 diabetes: what is the level of evidence? | Q26827760 | ||
| Efficacy of Berberine in Patients with Non-Alcoholic Fatty Liver Disease | Q27301440 | ||
| Silencing of microRNAs in vivo with 'antagomirs' | Q27860891 | ||
| Berberine Improves Glucose Metabolism in Diabetic Rats by Inhibition of Hepatic Gluconeogenesis | Q28477076 | ||
| Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily | Q28578854 | ||
| Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis | Q28591211 | ||
| miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting | Q29547487 | ||
| Positive regulation of hepatic miR-122 expression by HNF4α | Q34159452 | ||
| Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins | Q34552498 | ||
| Effect of Berberine on promoting the excretion of cholesterol in high-fat diet-induced hyperlipidemic hamsters | Q35996941 | ||
| Rationale for combination therapy with statin drugs in the treatment of dyslipidemia | Q36025974 | ||
| Sodium caprate augments the hypoglycemic effect of berberine via AMPK in inhibiting hepatic gluconeogenesis | Q37227111 | ||
| Antihyperglycemic action of rhodiola-aqeous extract in type1-like diabetic rats | Q37501307 | ||
| Berberine as a therapy for type 2 diabetes and its complications: From mechanism of action to clinical studies | Q38326750 | ||
| Effects of berberine and cinnamic acid on palmitic acid-induced intracellular triglyceride accumulation in NIT-1 pancreatic β cells | Q38930483 | ||
| Berberine up-regulates hepatic low-density lipoprotein receptor through Ras-independent but AMP-activated protein kinase-dependent Raf-1 activation | Q38958966 | ||
| Increased hepatic expression of miRNA-122 in patients infected with HCV genotype 3. | Q39322111 | ||
| Role of the nuclear receptors HNF4 alpha, PPAR alpha, and LXRs in the TNF alpha-mediated inhibition of human apolipoprotein A-I gene expression in HepG2 cells. | Q39780401 | ||
| Berberine lowers blood glucose in type 2 diabetes mellitus patients through increasing insulin receptor expression | Q39792130 | ||
| Mammalian hepatocyte differentiation requires the transcription factor HNF-4alpha. | Q40442109 | ||
| Analysis of circulating microRNA biomarkers in plasma and serum using quantitative reverse transcription-PCR (qRT-PCR). | Q41875540 | ||
| Free-fatty acid inhibition of insulin binding, degradation, and action in isolated rat hepatocytes | Q42481170 | ||
| Combination of simvastatin with berberine improves the lipid-lowering efficacy | Q46473880 | ||
| Evaluation of salivary glucose, amylase, and total protein in Type 2 diabetes mellitus patients | Q50438355 | ||
| Maternal high-fat diet consumption modulates hepatic lipid metabolism and microRNA-122 (miR-122) and microRNA-370 (miR-370) expression in offspring | Q50675151 | ||
| Hypoglycemic effect of protopanaxadiol-type ginsenosides and compound K on Type 2 diabetes mice induced by high-fat diet combining with streptozotocin via suppression of hepatic gluconeogenesis | Q51365779 | ||
| The role of the HNF4α enhancer in type 2 diabetes | Q57945274 | ||
| Nuevos tratamientos de la diabetes mellitus tipo 2. Mucho ruido y algunas nueces | Q59484700 | ||
| [Lipid metabolism disorder: detection and treatment. 5: Treatment of hyperlipidemia in manifest coronary heart disease, diabetes mellitus and hypertension. National cholesterol initiative] | Q67963771 | ||
| [Antidiarrheal and anti-inflammatory effects of berberine] | Q69800595 | ||
| Regulatory issues in the approval of new drugs for diabetes mellitus, dyslipidemia, and the metabolic syndrome | Q80162395 | ||
| Reduction of blood lipid by berberine in hyperlipidemic patients with chronic hepatitis or liver cirrhosis | Q80861504 | ||
| Cell-free miR-24 and miR-30d, potential diagnostic biomarkers in malignant effusions | Q82534572 | ||
| Analysis of circulating microRNA biomarkers for breast cancer detection: a meta-analysis | Q85262512 | ||
| Synthesis and structure–activity relationship of berberine analogues in LDLR up-regulation and AMPK activation | Q87431421 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 3 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | gluconeogenesis | Q191835 |
| lipid metabolism disorder | Q1476525 | ||
| hepatic gluconeogenesis | Q106966449 | ||
| P304 | page(s) | e0152097 | |
| P577 | publication date | 2016-01-01 | |
| P1433 | published in | PLOS One | Q564954 |
| P1476 | title | Berberine Attenuates Development of the Hepatic Gluconeogenesis and Lipid Metabolism Disorder in Type 2 Diabetic Mice and in Palmitate-Incubated HepG2 Cells through Suppression of the HNF-4α miR122 Pathway | |
| P478 | volume | 11 |
| Q58587589 | Berberine Attenuated Proliferation, Invasion and Migration by Targeting the AMPK/HNF4α/WNT5A Pathway in Gastric Carcinoma |
| Q55691409 | Berberine Protects Human Retinal Pigment Epithelial Cells from Hydrogen Peroxide-Induced Oxidative Damage through Activation of AMPK. |
| Q58798574 | Berberine Reduces Pyruvate-driven Hepatic Glucose Production by Limiting Mitochondrial Import of Pyruvate through Mitochondrial Pyruvate Carrier 1 |
| Q93198289 | Berberine Suppressed Tumor Growth through Regulating Fatty Acid Metabolism and Triggering Cell Apoptosis via Targeting FABPs |
| Q64898240 | Berberine alleviates hyperglycemia by targeting hepatic glucokinase in diabetic db/db mice. |
| Q38630807 | Berberine containing quadruple therapy for initial Helicobacter pylori eradication: An open-label randomized phase IV trial |
| Q64084960 | Berberine in Cardiovascular and Metabolic Diseases: From Mechanisms to Therapeutics |
| Q53752831 | Decreased lipid metabolism but increased FA biosynthesis are coupled with changes in liver microRNAs in obese subjects with NAFLD. |
| Q55285283 | Elevated hepatic expression of H19 long noncoding RNA contributes to diabetic hyperglycemia. |
| Q58781403 | Er-Miao-Fang Extracts Inhibits Adipose Lipolysis and Reduces Hepatic Gluconeogenesis via Suppression of Inflammation |
| Q91551847 | Fatty liver diseases, mechanisms, and potential therapeutic plant medicines |
| Q58696229 | Hypoglycemic Efficacy of Docking Selected Natural Compounds against α-Glucosidase and α-Amylase |
| Q36192941 | Identification and Verification of Potential Therapeutic Target Genes in Berberine-Treated Zucker Diabetic Fatty Rats through Bioinformatics Analysis |
| Q64986576 | Regulation of Cell Signaling Pathways by Berberine in Different Cancers: Searching for Missing Pieces of an Incomplete Jig-Saw Puzzle for an Effective Cancer Therapy. |
| Q92510491 | Rhizoma coptidis as a Potential Treatment Agent for Type 2 Diabetes Mellitus and the Underlying Mechanisms: A Review |
| Q41974093 | The Therapeutic Effect of Berberine in the Treatment of Nonalcoholic Fatty Liver Disease: A Meta-Analysis. |
| Q92980554 | The status of and trends in the pharmacology of berberine: a bibliometric review [1985-2018] |
| Q51245865 | Transcriptomic and proteomic analysis of potential therapeutic target genes in the liver of metformin‑treated Sprague‑Dawley rats with type 2 diabetes mellitus |
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