Sodium caprate augments the hypoglycemic effect of berberine via AMPK in inhibiting hepatic gluconeogenesis

scientific article published on August 16, 2012

Sodium caprate augments the hypoglycemic effect of berberine via AMPK in inhibiting hepatic gluconeogenesis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.MCE.2012.08.006
P953full work available online athttps://api.elsevier.com/content/article/PII:S0303720712003875?httpAccept=text/plain
https://api.elsevier.com/content/article/PII:S0303720712003875?httpAccept=text/xml
https://doi.org/10.1016/j.mce.2012.08.006
https://europepmc.org/articles/PMC3795615
https://europepmc.org/articles/pmc3795615?pdf=render
https://europepmc.org/articles/PMC3795615?pdf=render
P932PMC publication ID3795615
P698PubMed publication ID22922125

P2093author name stringLi Chen
Jing Li
Ming Zhang
Wei Li
Yanjun Liu
Xiaoyan Lv
Qiujing Wang
WenGuang Chang
Zhaojie Meng
P2860cites workEfficacy of berberine in patients with type 2 diabetes mellitusQ24645248
Global prevalence of diabetes: estimates for the year 2000 and projections for 2030Q27860575
The pivotal role of protein kinase C zeta (PKCzeta) in insulin- and AMP-activated protein kinase (AMPK)-mediated glucose uptake in muscle cellsQ28569456
Therapeutic effects of berberine in impaired glucose tolerance rats and its influence on insulin secretionQ28578447
The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metforminQ28590162
The CREB coactivator TORC2 is a key regulator of fasting glucose metabolismQ28594811
Metformin for type-2 diabetes mellitus. Systematic review and meta-analysisQ30862920
Enhancement of sodium caprate on intestine absorption and antidiabetic action of berberineQ33773083
Efficacy and safety of berberine for congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathyQ34535472
The characterization of high-fat diet and multiple low-dose streptozotocin induced type 2 diabetes rat modelQ37036239
AMP-activated protein kinase in the regulation of hepatic energy metabolism: from physiology to therapeutic perspectives.Q37401935
Research progress on the mechanism of single-Chinese medicinal herbs in treating diabetes mellitusQ37848181
Insulin modulates gluconeogenesis by inhibition of the coactivator TORC2.Q40084257
Berberine-stimulated glucose uptake in L6 myotubes involves both AMPK and p38 MAPK.Q40218653
Berberine, a natural plant product, activates AMP-activated protein kinase with beneficial metabolic effects in diabetic and insulin-resistant statesQ40250572
Inhibition of lipid synthesis through activation of AMP kinase: an additional mechanism for the hypolipidemic effects of berberineQ40310290
Alteration of 11beta-hydroxysteroid dehydrogenase type 1 in skeletal muscle in a rat model of type 2 diabetesQ42447239
Berberine activates GLUT1-mediated glucose uptake in 3T3-L1 adipocytesQ42521110
Berberine inhibits PTP1B activity and mimics insulin actionQ42826290
Berberine stimulates glucose transport through a mechanism distinct from insulin.Q42831138
Berberine modulates insulin signaling transduction in insulin-resistant cellsQ43207012
Ameliorative effect of berberine on endothelial dysfunction in diabetic rats induced by high-fat diet and streptozotocinQ43290690
P-glycoprotein-mediated transport of berberine across Caco-2 cell monolayersQ44218336
Hypoglycemic and insulin-sensitizing effects of berberine in high-fat diet- and streptozotocin-induced diabetic ratsQ51404403
[Antidiarrheal and anti-inflammatory effects of berberine]Q69800595
P433issue1-2
P407language of work or nameEnglishQ1860
P921main subjectgluconeogenesisQ191835
hepatic gluconeogenesisQ106966449
P304page(s)122-130
P577publication date2012-08-16
P1433published inMolecular and Cellular EndocrinologyQ1573600
P1476titleSodium caprate augments the hypoglycemic effect of berberine via AMPK in inhibiting hepatic gluconeogenesis
P478volume363

Reverse relations

cites work (P2860)
Q33819610A review of the effects of Berberis vulgaris and its major component, berberine, in metabolic syndrome
Q41682189Adenovirus vector-mediated macrophage erythroblast attacher (MAEA) overexpression in primary mouse hepatocytes attenuates hepatic gluconeogenesis
Q90146179Anti-inflammatory Property of AMP-activated Protein Kinase
Q28550972Berberine Attenuates Development of the Hepatic Gluconeogenesis and Lipid Metabolism Disorder in Type 2 Diabetic Mice and in Palmitate-Incubated HepG2 Cells through Suppression of the HNF-4α miR122 Pathway
Q92898827Berberine Attenuates Hyperglycemia by Inhibiting the Hepatic Glucagon Pathway in Diabetic Mice
Q88881645Berberine Improves Cognitive Deficiency and Muscular Dysfunction via Activation of the AMPK/SIRT1/PGC-1a Pathway in Skeletal Muscle from Naturally Aging Rats
Q95840735Berberine Improves Glucose and Lipid Metabolism in HepG2 Cells Through AMPKα1 Activation
Q38410398Berberine Pretreatment Confers Cardioprotection Against Ischemia-Reperfusion Injury in a Rat Model of Type 2 Diabetes
Q58798574Berberine Reduces Pyruvate-driven Hepatic Glucose Production by Limiting Mitochondrial Import of Pyruvate through Mitochondrial Pyruvate Carrier 1
Q33837285Berberine Reverses Hypoxia-induced Chemoresistance in Breast Cancer through the Inhibition of AMPK- HIF-1α.
Q46480430Berberine ameliorates experimental diabetes-induced renal inflammation and fibronectin by inhibiting the activation of RhoA/ROCK signaling
Q38326750Berberine as a therapy for type 2 diabetes and its complications: From mechanism of action to clinical studies
Q38421650Berberine improves insulin resistance in cardiomyocytes via activation of 5′-adenosine monophosphate-activated protein kinase
Q35819543Berberine inhibits hepatic gluconeogenesis via the LKB1-AMPK-TORC2 signaling pathway in streptozotocin-induced diabetic rats
Q35239952Berberine nanosuspension enhances hypoglycemic efficacy on streptozotocin induced diabetic C57BL/6 mice
Q54446441Cocoa flavonoids improve insulin signalling and modulate glucose production via AKT and AMPK in HepG2 cells
Q37741992Effect of berberine on the renal tubular epithelial-to-mesenchymal transition by inhibition of the Notch/snail pathway in diabetic nephropathy model KKAy mice
Q51019283Effects of type 2 diabetes mellitus on the pharmacokinetics of berberine in rats
Q55285283Elevated hepatic expression of H19 long noncoding RNA contributes to diabetic hyperglycemia.
Q38490486Gene expression profiling and pathway analysis of hepatotoxicity induced by triptolide in Wistar rats
Q48223878Genistein represses PEPCK-C expression in an insulin-independent manner in HepG2 cells and in alloxan-induced diabetic mice.
Q35008532Hematopoietic tissue factor-protease-activated receptor 2 signaling promotes hepatic inflammation and contributes to pathways of gluconeogenesis and steatosis in obese mice
Q98464588Highly bioavailable Berberine formulation improves Glucocorticoid Receptor-mediated Insulin Resistance via reduction in association of the Glucocorticoid Receptor with phosphatidylinositol-3-kinase
Q51282796Jiangtang Xiaozhi Recipe () prevents diabetic retinopathy in streptozotocin-induced diabetic rats
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Q26752335PGC-1α, glucose metabolism and type 2 diabetes mellitus
Q61810256Unraveling the Regulation of Hepatic Gluconeogenesis
Q36988577Update on Berberine in Nonalcoholic Fatty Liver Disease

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