Effect of berberine on the renal tubular epithelial-to-mesenchymal transition by inhibition of the Notch/snail pathway in diabetic nephropathy model KKAy mice

scientific article published on 31 March 2017

Effect of berberine on the renal tubular epithelial-to-mesenchymal transition by inhibition of the Notch/snail pathway in diabetic nephropathy model KKAy mice is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.2147/DDDT.S124971
P932PMC publication ID5384688
P698PubMed publication ID28408805

P2093author name stringYawei Huang
Meijuan Yang
Xinxue Zhang
Guannan Yang
Amin Wu
Zongjiang Zhao
Yonghui Miao
P2860cites workThe basics of epithelial-mesenchymal transitionQ24652992
Genomic organization, expression, and chromosome location of the human SNAIL gene (SNAI1) and a related processed pseudogene (SNAI1P)Q28139498
Berberine attenuates lipopolysaccharide-induced extracelluar matrix accumulation and inflammation in rat mesangial cells: involvement of NF-κB signaling pathwayQ28573256
Therapeutic effects of berberine in impaired glucose tolerance rats and its influence on insulin secretionQ28578447
Notch signaling in kidney developmentQ28589148
Avosentan for overt diabetic nephropathyQ33702404
Epithelial Notch signaling regulates interstitial fibrosis development in the kidneys of mice and humansQ34245363
The global implications of diabetes and cancerQ34423638
Snail mediates E-cadherin repression by the recruitment of the Sin3A/histone deacetylase 1 (HDAC1)/HDAC2 complexQ34550834
Relaxin prevents cardiac fibroblast-myofibroblast transition via notch-1-mediated inhibition of TGF-β/Smad3 signaling.Q34737733
The effect of chinese herbal medicine on albuminuria levels in patients with diabetic nephropathy: a systematic review and meta-analysis.Q34996116
The story of Notch and chronic kidney diseaseQ35188732
Expression of Notch pathway proteins correlates with albuminuria, glomerulosclerosis, and renal functionQ35189006
Sustained antidiabetic effects of a berberine-containing Chinese herbal medicine through regulation of hepatic gene expression.Q35857713
Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibrosisQ36104434
Berberine protects human renal proximal tubular cells from hypoxia/reoxygenation injury via inhibiting endoplasmic reticulum and mitochondrial stress pathwaysQ36690275
Polycomb complex 2 is required for E-cadherin repression by the Snail1 transcription factor.Q36804667
Notch signaling in diabetic nephropathyQ36916676
A glimpse of various pathogenetic mechanisms of diabetic nephropathyQ36979205
Protective Effects of Berberine on Renal Injury in Streptozotocin (STZ)-Induced Diabetic MiceQ37210162
Sodium caprate augments the hypoglycemic effect of berberine via AMPK in inhibiting hepatic gluconeogenesisQ37227111
The role of vitamin E and oxidative stress in diabetes complicationsQ37716082
Berberine: new perspectives for old remedies.Q38030353
Molecular targets for treatment of kidney fibrosisQ38062404
Role of the endothelial-to-mesenchymal transition in renal fibrosis of chronic kidney diseaseQ38083596
Learning from berberine: Treating chronic diseases through multiple targetsQ38156718
Epigenetically altered wound healing in keloid fibroblasts.Q38343232
Non-communicable diseases in the Asia-Pacific region: Prevalence, risk factors and community-based preventionQ38544600
Berberine, a plant alkaloid with lipid- and glucose-lowering properties: From in vitro evidence to clinical studiesQ38621266
Review of Herbal Traditional Chinese Medicine for the Treatment of Diabetic NephropathyQ38663562
Notch signaling mediates TGF-β1-induced epithelial-mesenchymal transition through the induction of Snai1.Q39397113
Treatment of diabetes using traditional Chinese medicine: past, present and futureQ39562298
Differential regulation of Snail by hypoxia and hyperglycemia in human proximal tubule cellsQ39682030
Snail1-induced partial epithelial-to-mesenchymal transition drives renal fibrosis in mice and can be targeted to reverse established diseaseQ40666383
Effects of berberine on matrix accumulation and NF-kappa B signal pathway in alloxan-induced diabetic mice with renal injuryQ43071829
Notch mediated epithelial to mesenchymal transformation is associated with increased expression of the Snail transcription factorQ43116436
The effect of the "yellow" mutation at the mouse agouti locus on the hormonal profile of pregnancy and lactationQ43199410
Berberine suppresses high glucose-induced TGF-β1 and fibronectin synthesis in mesangial cells through inhibition of sphingosine kinase 1/AP-1 pathwayQ44036628
Berberine exerts nephroprotective effect against cisplatin-induced kidney damage through inhibition of oxidative/nitrosative stress, inflammation, autophagy and apoptosis.Q44773514
Berberine reduces fibronectin and collagen accumulation in rat glomerular mesangial cells cultured under high glucose conditionQ46163975
Erythromycin ameliorates renal injury via anti-inflammatory effects in experimental diabetic ratsQ46757977
The effect of ruboxistaurin on nephropathy in type 2 diabetesQ46774857
Renoprotective effects of berberine and its possible molecular mechanisms in combination of high-fat diet and low-dose streptozotocin-induced diabetic rats.Q51348247
Comparative genomics on SNAI1, SNAI2, and SNAI3 orthologs.Q53354668
Snail silencing effectively suppresses tumour growth and invasiveness.Q54576035
Combination of melatonin and certain drugs for treatment of diabetic nephropathy in streptozotocin-induced diabetes in rats.Q64915804
Laboratory animals exhibiting obesity and diabetes syndromesQ67542769
General Survey of Diabetic Features of Yellow KK MiceQ71566421
Diabetic nephropathy in the Arab Gulf countriesQ82710508
Renal tubulointerstitial fibrosis in OVE26 type 1 diabetic miceQ82818036
The effects of the Chinese medicine ZiBu PiYin recipe on the hippocampus in a rat model of diabetes-associated cognitive decline: a proteomic analysisQ83920033
Zhenqing recipe alleviates diabetic nephropathy in experimental type 2 diabetic rats through suppression of SREBP-1cQ84077897
High glucose-induced RhoA activation requires caveolae and PKCβ1-mediated ROS generationQ85048393
Diabetes prevention and continuing health-care reform in ChinaQ86547791
Synergistic effects of leflunomide and benazepril in streptozotocin-induced diabetic nephropathyQ87935970
Transforming growth factor-beta induces renal epithelial jagged-1 expression in fibrotic diseaseQ95788128
P275copyright licenseCreative Commons Attribution-NonCommercial 3.0 UnportedQ18810331
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P407language of work or nameEnglishQ1860
P921main subjectdiabetic nephropathyQ1129105
P304page(s)1065-1079
P577publication date2017-03-31
P1433published inDrug Design, Development and TherapyQ2566724
P1476titleEffect of berberine on the renal tubular epithelial-to-mesenchymal transition by inhibition of the Notch/snail pathway in diabetic nephropathy model KKAy mice
P478volume11

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cites work (P2860)
Q64093257Berberine Protects Glomerular Podocytes via Inhibiting Drp1-Mediated Mitochondrial Fission and Dysfunction
Q55108878Berberine ameliorates diabetic nephropathy by inhibiting TLR4/NF-κB pathway.
Q93085884Danggui buxue tang inhibited mesangial cell proliferation and extracellular matrix accumulation through GAS5/NF-κB pathway
Q42364411Effect of echinacoside on kidney fibrosis by inhibition of TGF-β1/Smads signaling pathway in the db/db mice model of diabetic nephropathy
Q47610119Renal vectorial transport of berberine mediated by organic cation transporter 2 (OCT2) and multidrug and toxin extrusion proteins 1 (MATE1) in rats.
Q92510491Rhizoma coptidis as a Potential Treatment Agent for Type 2 Diabetes Mellitus and the Underlying Mechanisms: A Review
Q94950021Therapeutic Application of Nutraceuticals in Diabetic Nephropathy: Current Evidence and Future Implications

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