Therapeutic Application of Nutraceuticals in Diabetic Nephropathy: Current Evidence and Future Implications

scientific article published on 16 May 2020

Therapeutic Application of Nutraceuticals in Diabetic Nephropathy: Current Evidence and Future Implications is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1127644725
P356DOI10.1002/DMRR.3336
P698PubMed publication ID32415805

P50authorAzam HosseinzadehQ56722221
P2093author name stringKarim Hemati
Saeed Mehrzadi
Mohammad Hossein Pourhanifeh
Ehsan Dehdashtian
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Targeting proteins for degradationQ28261886
Diminished loss of proteoglycans and lack of albuminuria in protein kinase C-alpha-deficient diabetic miceQ28274074
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AMPK: a nutrient and energy sensor that maintains energy homeostasisQ29615410
Quercetin improves lipid metabolism via SCAP-SREBP2-LDLr signaling pathway in early stage diabetic nephropathyQ93026456
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PPAR gamma 2 prevents lipotoxicity by controlling adipose tissue expandability and peripheral lipid metabolismQ33283063
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Interplay between Akt and p38 MAPK pathways in the regulation of renal tubular cell apoptosis associated with diabetic nephropathyQ33589104
Control of mitochondrial biogenesis and function by the ubiquitin-proteasome systemQ33628850
HRD1-Mediated IGF-1R Ubiquitination Contributes to Renal Protection of Resveratrol in db/db MiceQ33631382
Serum creatinine elevation after renin-angiotensin system blockade and long term cardiorenal risks: cohort studyQ33647372
Curcumin activates the p38MPAK-HSP25 pathway in vitro but fails to attenuate diabetic nephropathy in DBA2J mice despite urinary clearance documented by HPLCQ33745769
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Quercetin and allopurinol ameliorate kidney injury in STZ-treated rats with regulation of renal NLRP3 inflammasome activation and lipid accumulationQ34305376
Berberine reduces fibronectin expression by suppressing the S1P-S1P2 receptor pathway in experimental diabetic nephropathy modelsQ34399505
Novel curcumin analog C66 prevents diabetic nephropathy via JNK pathway with the involvement of p300/CBP-mediated histone acetylationQ34666690
Renoprotective, anti-oxidative and anti-apoptotic effects of oral low-dose quercetin in the C57BL/6J model of diabetic nephropathy.Q34738579
Targeting JNK by a new curcumin analog to inhibit NF-kB-mediated expression of cell adhesion molecules attenuates renal macrophage infiltration and injury in diabetic miceQ35048212
Resveratrol attenuates diabetic nephropathy via modulating angiogenesisQ35061522
Resveratrol retards progression of diabetic nephropathy through modulations of oxidative stress, proinflammatory cytokines, and AMP-activated protein kinaseQ35147432
Impaired mitochondrial complex III and melatonin responsive reactive oxygen species generation in kidney mitochondria of db/db miceQ35190860
A new Classification of Diabetic Nephropathy 2014: a report from Joint Committee on Diabetic NephropathyQ35192219
Molecular docking studies of (4Z, 12Z)-cyclopentadeca-4, 12-dienone from Grewia hirsuta with some targets related to type 2 diabetesQ35606228
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Renoprotective effect of berberine via regulating the PGE2 -EP1-Gαq-Ca(2+) signalling pathway in glomerular mesangial cells of diabetic ratsQ35995332
The protective effects of oral low-dose quercetin on diabetic nephropathy in hypercholesterolemic mice.Q36018270
PPARgamma in human and mouse physiologyQ36063081
Pathogenetic mechanisms of diabetic nephropathyQ36153062
Inhibition of high glucose-induced inflammatory response and macrophage infiltration by a novel curcumin derivative prevents renal injury in diabetic ratsQ36159004
Plasminogen activator inhibitor-1 and diabetic nephropathy.Q36262378
Change in post-translational modifications of histone H3, heat-shock protein-27 and MAP kinase p38 expression by curcumin in streptozotocin-induced type I diabetic nephropathy.Q36510007
Protective Effects of Curcumin on Renal Oxidative Stress and Lipid Metabolism in a Rat Model of Type 2 Diabetic NephropathyQ36707919
Regulation of interplay between autophagy and apoptosis in the diabetic heart: new role of AMPK.Q36769740
Resveratrol increases AdipoR1 and AdipoR2 expression in type 2 diabetic nephropathyQ36994616
Amelioration of streptozotocin-induced diabetic nephropathy by melatonin, quercetin, and resveratrol in rats.Q53052202
Melatonin nephroprotective action in Zucker diabetic fatty rats involves its inhibitory effect on NADPH oxidase.Q53295837
Renal function after new treatment with renin-angiotensin system blockers.Q53447763
Curcumin prevents diabetic nephropathy against inflammatory response via reversing caveolin-1 Tyr14 phosphorylation influenced TLR4 activation.Q53453918
Nephrin loss in experimental diabetic nephropathy is prevented by deletion of protein kinase C alpha signaling in-vivo.Q53589254
Role of MKK3-p38 MAPK signalling in the development of type 2 diabetes and renal injury in obese db/db mice.Q54782198
Berberine ameliorates diabetic nephropathy by inhibiting TLR4/NF-κB pathway.Q55108878
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A role for AMP-activated protein kinase in diabetes-induced renal hypertrophyQ64018940
Combination of melatonin and certain drugs for treatment of diabetic nephropathy in streptozotocin-induced diabetes in rats.Q64915804
The effect of a new specific ?-amylase inhibitor on post-prandial glucose and insulin excursions in normal subjects and Type 2 (non-insulin-dependent) diabetic patientsQ70362196
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Quercetin ameliorates diabetic nephropathy by reducing the expressions of transforming growth factor-β1 and connective tissue growth factor in streptozotocin-induced diabetic ratsQ82096732
Resveratrol protects against hyperglycemia-induced oxidative damage to mitochondria by activating SIRT1 in rat mesangial cellsQ82123093
Curcumin attenuates diabetic nephropathy by inhibiting PKC-α and PKC-β1 activity in streptozotocin-induced type I diabetic ratsQ82299221
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Resveratrol ameliorates podocyte damage in diabetic mice via SIRT1/PGC-1α mediated attenuation of mitochondrial oxidative stressQ91310866
Melatonin Attenuates Endothelial-to-Mesenchymal Transition of Glomerular Endothelial Cells via Regulating miR-497/ROCK in Diabetic NephropathyQ91429858
Evaluating the protective effects of melatonin on di(2-ethylhexyl) phthalate-induced testicular injury in adult miceQ91647136
Ramipril and resveratrol co-treatment attenuates RhoA/ROCK pathway-regulated early-stage diabetic nephropathy-associated glomerulosclerosis in streptozotocin-induced diabetic ratsQ91817215
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Quercetin inhibited mesangial cell proliferation of early diabetic nephropathy through the Hippo pathwayQ92906966
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Protective Effects of Berberine on Renal Injury in Streptozotocin (STZ)-Induced Diabetic MiceQ37210162
New therapeutic agents in diabetic nephropathyQ37559164
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The many faces of the mitochondrial TIM23 complexQ37684145
Resveratrol protects podocytes against apoptosis via stimulation of autophagy in a mouse model of diabetic nephropathyQ37736609
Effect of berberine on the renal tubular epithelial-to-mesenchymal transition by inhibition of the Notch/snail pathway in diabetic nephropathy model KKAy miceQ37741992
Inflammatory molecules and pathways in the pathogenesis of diabetic nephropathy.Q37871339
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Renal protective effects of resveratrolQ38174888
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Protein translocation channel of mitochondrial inner membrane and matrix-exposed import motor communicate via two-domain coupling proteinQ38358839
The Nutraceutical Bioavailability Classification Scheme: Classifying Nutraceuticals According to Factors Limiting their Oral Bioavailability.Q38364262
Experimental and clinical aspects of melatonin and clock genes in diabetesQ38436840
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Berberine, a plant alkaloid with lipid- and glucose-lowering properties: From in vitro evidence to clinical studiesQ38621266
Hyperoside pre-treatment prevents glomerular basement membrane damage in diabetic nephropathy by inhibiting podocyte heparanase expressionQ38661556
Inhibition of high glucose-induced inflammation and fibrosis by a novel curcumin derivative prevents renal and heart injury in diabetic miceQ38697493
Resveratrol ameliorates diabetic nephropathy in rats through negative regulation of the p38 MAPK/TGF-β1 pathwayQ38701033
Olmesartan Prevents Microalbuminuria in db/db Diabetic Mice Through Inhibition of Angiotensin II/p38/SIRT1-Induced Podocyte ApoptosisQ38729813
Thioredoxin-Interacting Protein Mediates NLRP3 Inflammasome Activation Involved in the Susceptibility to Ischemic Acute Kidney Injury in Diabetes.Q38729962
Melatonin Attenuates Contrast-Induced Nephropathy in Diabetic Rats: The Role of Interleukin-33 and Oxidative StressQ38738488
Sirt1 is essential for resveratrol enhancement of hypoxia-induced autophagy in the type 2 diabetic nephropathy rat.Q38794575
Quercetin inhibits the mTORC1/p70S6K signaling-mediated renal tubular epithelial-mesenchymal transition and renal fibrosis in diabetic nephropathyQ38855746
Combined potentiating action of phytochemical(s) from Cinnamomum tamala and Aloe vera for their anti-diabetic and insulinomimetic effect using in vivo rat and in vitro NIH/3T3 cell culture systemQ38925777
Health-beneficial nutraceuticals-myth or reality?Q39030138
Resveratrol is a class IA phosphoinositide 3-kinase inhibitorQ39253076
Severe acute respiratory syndrome coronavirus replication is severely impaired by MG132 due to proteasome-independent inhibition of M-calpainQ39316066
High glucose induces renal mesangial cell proliferation and fibronectin expression through JNK/NF-κB/NADPH oxidase/ROS pathway, which is inhibited by resveratrol.Q39412268
Berberine, a natural plant product, activates AMP-activated protein kinase with beneficial metabolic effects in diabetic and insulin-resistant statesQ40250572
Omega-3 fatty acids decrease protein kinase expression in human breast cancer cellsQ40779994
Curcumin ameliorates macrophage infiltration by inhibiting NF-κB activation and proinflammatory cytokines in streptozotocin induced-diabetic nephropathy.Q41854992
Curcumin Ameliorates Diabetic Nephropathy by Suppressing NLRP3 Inflammasome Signaling.Q42177918
P921main subjectdiabetic nephropathyQ1129105
P577publication date2020-05-16
P1433published inDiabetes - Metabolism: Research and ReviewsQ15750056
P1476titleTherapeutic Application of Nutraceuticals in Diabetic Nephropathy: Current Evidence and Future Implications

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