hnRNP A1 mediates the activation of the IRES-dependent SREBP-1a mRNA translation in response to endoplasmic reticulum stress

scientific journal article

hnRNP A1 mediates the activation of the IRES-dependent SREBP-1a mRNA translation in response to endoplasmic reticulum stress is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1042/BJ20120906
P698PubMed publication ID23106379

P2093author name stringAntonio Gnoni
Fabrizio Damiano
Luisa Siculella
Alessio Rochira
Romina Tocci
Simone Alemanno
P2860cites workInteraction between hnRNPA1 and IkappaBalpha is required for maximal activation of NF-kappaB-dependent transcriptionQ24514760
Functional characterization of the X-linked inhibitor of apoptosis (XIAP) internal ribosome entry site element: role of La autoantigen in XIAP translationQ24554132
Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cellsQ24561820
The VEGF IRESes are differentially susceptible to translation inhibition by miR-16Q24647478
Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: Insig renders sorting signal in Scap inaccessible to COPII proteinsQ24683954
Searching for IRESQ27477494
SREBP-1c transcription factor and lipid homeostasis: clinical perspectiveQ28291930
Hepatic steatosis: a role for de novo lipogenesis and the transcription factor SREBP-1cQ28297047
SREBP transcription factors: master regulators of lipid homeostasisQ28297603
Homocysteine-induced endoplasmic reticulum stress causes dysregulation of the cholesterol and triglyceride biosynthetic pathwaysQ28365886
Regulation of hepatic lipogenesis by the transcription factor XBP1Q28507784
3,5,3'triiodo-L-thyronine induces SREBP-1 expression by non-genomic actions in human HEP G2 cells.Q54568970
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetesQ28575190
Polyunsaturated fatty acids suppress hepatic sterol regulatory element-binding protein-1 expression by accelerating transcript decayQ31742604
Regulation of heterogenous nuclear ribonucleoprotein A1 transport by phosphorylation in cells stressed by osmotic shockQ33928652
Sterol regulatory element-binding proteins (SREBPs): key regulators of nutritional homeostasis and insulin actionQ33996668
C-Myc 5' untranslated region contains an internal ribosome entry segmentQ34065968
n-6 PUFAs downregulate expression of the tricarboxylate carrier in rat liver by transcriptional and posttranscriptional mechanisms.Q34310522
The internal ribosome entry site-mediated translation of antiapoptotic protein XIAP is modulated by the heterogeneous nuclear ribonucleoproteins C1 and C2.Q34462937
hnRNP A1 relocalization to the stress granules reflects a role in the stress response.Q34548446
Cellular IRES-mediated translation: the war of ITAFs in pathophysiological states.Q34624747
Regulation of sterol synthesis in eukaryotes.Q34657925
New perspectives in the regulation of hepatic glycolytic and lipogenic genes by insulin and glucose: a role for the transcription factor sterol regulatory element binding protein-1cQ34682304
Endoplasmic reticulum stress and the unfolded protein response in nonalcoholic fatty liver diseaseQ35055531
Regulation of HMG-CoA reductase in mammals and yeastQ35250146
The unfolded protein response--a stress signaling pathway of the endoplasmic reticulumQ35885345
Cytoplasmic relocalization of heterogeneous nuclear ribonucleoprotein A1 controls translation initiation of specific mRNAs.Q36173849
RNA-binding proteins HuR and PTB promote the translation of hypoxia-inducible factor 1alphaQ36421108
A cytoplasmic 57-kDa protein that is required for translation of picornavirus RNA by internal ribosomal entry is identical to the nuclear pyrimidine tract-binding proteinQ36481910
SREBP in signal transduction: cholesterol metabolism and beyondQ36736642
Heterogeneous nuclear ribonucleoprotein A1 regulates cyclin D1 and c-myc internal ribosome entry site function through Akt signalingQ36838764
Endoplasmic reticulum stress markers are associated with obesity in nondiabetic subjectsQ36971939
Endoplasmic reticulum stress is reduced in tissues of obese subjects after weight lossQ37105351
GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in miceQ37170811
Central role for liver X receptor in insulin-mediated activation of Srebp-1c transcription and stimulation of fatty acid synthesis in liver.Q37388544
Nutritional related liver disease: targeting the endoplasmic reticulum stressQ37591100
Functional diversity of the hnRNPs: past, present and perspectivesQ37783316
Translational control of the sterol-regulatory transcription factor SREBP-1 mRNA in response to serum starvation or ER stress is mediated by an internal ribosome entry site.Q38343651
Distinct RNP complexes of shuttling hnRNP proteins with pre-mRNA and mRNA: candidate intermediates in formation and export of mRNA.Q39528692
hnRNP A1 nucleocytoplasmic shuttling activity is required for normal myelopoiesis and BCR/ABL leukemogenesisQ39674140
ELAV/Hu proteins inhibit p27 translation via an IRES element in the p27 5'UTR.Q39864466
Functional analysis of rat liver citrate carrier promoter: differential responsiveness to polyunsaturated fatty acids.Q39939290
Tumor necrosis factor-alpha can provoke cleavage and activation of sterol regulatory element-binding protein in ethanol-exposed cells via a caspase-dependent pathway that is cholesterol insensitiveQ39960171
The MKK(3/6)-p38-signaling cascade alters the subcellular distribution of hnRNP A1 and modulates alternative splicing regulationQ40886370
UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators.Q42041480
Identification of a motif that mediates polypyrimidine tract-binding protein-dependent internal ribosome entryQ42699424
Insulin effects on sterol regulatory-element-binding protein-1c (SREBP-1c) transcriptional activity in rat hepatocytes.Q42997321
Structural and functional characterization of F(o)F(1)-ATP synthase on the extracellular surface of rat hepatocytes.Q46385528
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectendoplasmic reticulumQ79927
response to antibioticQ14818070
response to organic cyclic compoundQ14820916
cellular response to antibioticQ14864811
cellular response to organic cyclic compoundQ14885641
P304page(s)543–553
P577publication date2013-01-15
P1433published inBiochemical JournalQ864221
P1476titlehnRNP A1 mediates the activation of the IRES-dependent SREBP-1a mRNA translation in response to endoplasmic reticulum stress
P478volume449

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cites work (P2860)
Q57048123Alternative mechanisms of translation initiation: An emerging dynamic regulator of the proteome in health and disease
Q38198617Establishment of chronic hepatitis C virus infection: translational evasion of oxidative defence
Q26779296Exploring Internal Ribosome Entry Sites as Therapeutic Targets
Q37654733Heterogeneous nuclear ribonucleoprotein A1 regulates rhythmic synthesis of mouse Nfil3 protein via IRES-mediated translation
Q64258342IRES Trans-Acting Factors, Key Actors of the Stress Response
Q89697924In Steatotic Cells, ATP-Citrate Lyase mRNA Is Efficiently Translated through a Cap-Independent Mechanism, Contributing to the Stimulation of De Novo Lipogenesis
Q38866763Molecular mechanisms of mTOR regulation by stress
Q39028088More than just scanning: the importance of cap-independent mRNA translation initiation for cellular stress response and cancer.
Q49784908Oleic Acid and Hydroxytyrosol Inhibit Cholesterol and Fatty Acid Synthesis in C6 Glioma Cells
Q33635946PRMT5 regulates IRES-dependent translation via methylation of hnRNP A1.
Q37375354RNA-binding proteins impacting on internal initiation of translation
Q64244246The PERK Branch of the Unfolded Protein Response Promotes DLL4 Expression by Activating an Alternative Translation Mechanism
Q38825911The role of ER stress in lipid metabolism and lipotoxicity
Q38876640Therapeutic potential of targeting IRES-dependent c-myc translation in multiple myeloma cells during ER stress.
Q89944336Translational Regulations in Response to Endoplasmic Reticulum Stress in Cancers
Q41962611hnRNP A1-mediated translational regulation of the G quadruplex-containing RON receptor tyrosine kinase mRNA linked to tumor progression
Q38142712hnRNP A1: the Swiss army knife of gene expression

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