Translational control of the sterol-regulatory transcription factor SREBP-1 mRNA in response to serum starvation or ER stress is mediated by an internal ribosome entry site.

scientific article published on August 2010

Translational control of the sterol-regulatory transcription factor SREBP-1 mRNA in response to serum starvation or ER stress is mediated by an internal ribosome entry site. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1042/BJ20091827
P698PubMed publication ID20513236
P5875ResearchGate publication ID44640389

P50authorLuisa SiculellaQ48630459
Fabrizio DamianoQ49785650
P2093author name stringGabriele V Gnoni
Simone Alemanno
P2860cites workMfold web server for nucleic acid folding and hybridization predictionQ24498105
Hypoxia-inducible factor-1alpha mRNA contains an internal ribosome entry site that allows efficient translation during normoxia and hypoxiaQ24524140
Identification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory element-binding protein 1c gene promoterQ24550969
Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNAQ27861043
Internal ribosome entry sites in eukaryotic mRNA moleculesQ28205551
SREBP transcription factors: master regulators of lipid homeostasisQ28297603
Homocysteine-induced endoplasmic reticulum stress causes dysregulation of the cholesterol and triglyceride biosynthetic pathwaysQ28365886
Regulation of hepatic lipogenesis by the transcription factor XBP1Q28507784
Polyunsaturated fatty acids suppress hepatic sterol regulatory element-binding protein-1 expression by accelerating transcript decayQ31742604
Transcriptional regulation of VEGF-A by the unfolded protein response pathwayQ33539754
Hyperphosphorylation regulates the activity of SREBP1 during mitosisQ33920062
Translation initiation factor modifications and the regulation of protein synthesis in apoptotic cellsQ33964325
Sterol regulatory element-binding proteins (SREBPs): key regulators of nutritional homeostasis and insulin actionQ33996668
C-Myc 5' untranslated region contains an internal ribosome entry segmentQ34065968
Internal ribosome initiation of translation and the control of cell death.Q34069648
The SREBP pathway--insights from Insigs and insectsQ34223258
Differential effects of coconut oil- and fish oil-enriched diets on tricarboxylate carrier in rat liver mitochondriaQ34278572
Regulation of gene expression by internal ribosome entry sites or cryptic promoters: the eIF4G storyQ34325611
Different dietary fatty acids have dissimilar effects on activity and gene expression of mitochondrial tricarboxylate carrier in rat liverQ34374985
Nutritional and insulin regulation of fatty acid synthetase and leptin gene expression through ADD1/SREBP1.Q34451430
Regulation of sterol synthesis in eukaryotes.Q34657925
New perspectives in the regulation of hepatic glycolytic and lipogenic genes by insulin and glucose: a role for the transcription factor sterol regulatory element binding protein-1cQ34682304
The implications of structured 5' untranslated regions on translation and diseaseQ36013970
SREBPs: sterol-regulated transcription factorsQ36416721
SREBP in signal transduction: cholesterol metabolism and beyondQ36736642
Cap-independent regulation of gene expression in apoptosisQ37000364
Reprogramming mRNA translation during stressQ37115046
GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in miceQ37170811
Regulation of sterol regulatory element binding proteins in livers of fasted and refed miceQ37375695
Central role for liver X receptor in insulin-mediated activation of Srebp-1c transcription and stimulation of fatty acid synthesis in liver.Q37388544
Increased levels of nuclear SREBP-1c associated with fatty livers in two mouse models of diabetes mellitusQ38319698
Functional analysis of rat liver citrate carrier promoter: differential responsiveness to polyunsaturated fatty acids.Q39939290
Initiation of Apaf-1 translation by internal ribosome entryQ40895986
UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators.Q42041480
Insulin effects on sterol regulatory-element-binding protein-1c (SREBP-1c) transcriptional activity in rat hepatocytes.Q42997321
Adenovirus-mediated overexpression of sterol regulatory element binding protein-1c mimics insulin effects on hepatic gene expression and glucose homeostasis in diabetic mice.Q43778752
The role of liver X receptor-alpha in the fatty acid regulation of hepatic gene expressionQ44548838
Preferential translation of internal ribosome entry site-containing mRNAs during the mitotic cycle in mammalian cellsQ46432262
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)603-612
P577publication date2010-08-01
P1433published inBiochemical JournalQ864221
P1476titleTranslational control of the sterol-regulatory transcription factor SREBP-1 mRNA in response to serum starvation or ER stress is mediated by an internal ribosome entry site
P478volume429

Reverse relations

cites work (P2860)
Q896293181,25-hydroxyvitamin D3 decreases endoplasmic reticulum stress-induced inflammatory response in mammary epithelial cells
Q545689703,5,3'triiodo-L-thyronine induces SREBP-1 expression by non-genomic actions in human HEP G2 cells.
Q92162437Alternative Mechanisms of mRNA Translation Initiation in Cellular Stress Response and Cancer
Q59351846CVB3 Nonstructural 2A Protein Modulates SREBP1a Signaling via the MEK/ERK Pathway
Q26744030Cap-Independent Translational Control of Carcinogenesis
Q29568201Characterization of Human and Yeast Mitochondrial Glycine Carriers with Implications for Heme Biosynthesis and Anemia.
Q41791152Conditioned Media Downregulates Nuclear Expression of Nrf2.
Q35779442ER Stress and Lipid Metabolism in Adipocytes
Q37834712Endoplasmic reticulum stress and lipid dysregulation
Q39148101Endoplasmic reticulum stress leads to lipid accumulation through upregulation of SREBP-1c in normal hepatic and hepatoma cells
Q89697924In Steatotic Cells, ATP-Citrate Lyase mRNA Is Efficiently Translated through a Cap-Independent Mechanism, Contributing to the Stimulation of De Novo Lipogenesis
Q26866358Internal ribosome entry site-based vectors for combined gene therapy
Q30355131Lipotoxicity in the liver.
Q37296724MiR-103 controls milk fat accumulation in goat (Capra hircus) mammary gland during lactation.
Q39028088More than just scanning: the importance of cap-independent mRNA translation initiation for cellular stress response and cancer.
Q42236573Myocardial ischemic reperfusion induces de novo Nrf2 protein translation.
Q40923110PI3K-Akt signaling pathway upregulates hepatitis C virus RNA translation through the activation of SREBPs
Q35160101Preference of IRES-mediated initiation of translation during hibernation in golden-mantled ground squirrels, Spermophilus lateralis
Q37148306Pro-apoptotic miRNA-128-2 modulates ABCA1, ABCG1 and RXRα expression and cholesterol homeostasis
Q42407732SREBP-1 Mediates Angiotensin II-Induced TGF-β1 Upregulation and Glomerular Fibrosis
Q33652041Smoke exposure causes endoplasmic reticulum stress and lipid accumulation in retinal pigment epithelium through oxidative stress and complement activation
Q34860549The contribution of endoplasmic reticulum stress to liver diseases
Q38825911The role of ER stress in lipid metabolism and lipotoxicity
Q35552009eIF4E and eIF4GI have distinct and differential imprints on multiple myeloma's proteome and signaling
Q28573820hnRNP A1 mediates the activation of the IRES-dependent SREBP-1a mRNA translation in response to endoplasmic reticulum stress

Search more.