human | Q5 |
P8168 | FactGrid item ID | Q885240 |
P10299 | Leopoldina member ID (new) | reinhard-faessler |
P3413 | Leopoldina member ID (superseded) | 7527 |
P496 | ORCID iD | 0000-0002-0145-6937 |
P108 | employer | Max Planck Society | Q158085 |
P734 | family name | Fässler | Q66737788 |
Fässler | Q66737788 | ||
Fässler | Q66737788 | ||
P735 | given name | Reinhard | Q18177338 |
Reinhard | Q18177338 | ||
P463 | member of | German Academy of Sciences Leopoldina | Q543804 |
P106 | occupation | researcher | Q1650915 |
P21 | sex or gender | male | Q6581097 |
Q46158180 | A VASP-Rac-soluble guanylyl cyclase pathway controls cGMP production in adipocytes |
Q40423523 | A firm grip does not always pay off: a new Phact(r) 4 integrin signaling |
Q48099760 | A forceful connection: mechanoregulation of oncogenic YAP. |
Q36512219 | A hypomorphic mouse model of dystrophic epidermolysis bullosa reveals mechanisms of disease and response to fibroblast therapy |
Q44965368 | A molecular toolkit for the functionalization of titanium-based biomaterials that selectively control integrin-mediated cell adhesion |
Q30528487 | A novel role of sphingosine 1-phosphate receptor S1pr1 in mouse thrombopoiesis |
Q40364120 | ADAM12-mediated focal adhesion formation is differently regulated by beta1 and beta3 integrins |
Q28511542 | All four members of the Ten-m/Odz family of transmembrane proteins form dimers |
Q36661709 | An essential requirement for β1 integrin in the assembly of extracellular matrix proteins within the vascular wall |
Q36909825 | Analysis of integrin functions in peri-implantation embryos, hematopoietic system, and skin |
Q30541878 | Angiopoietin 2 mediates microvascular and hemodynamic alterations in sepsis |
Q36161003 | Antiangiogenic proteins require plasma fibronectin or vitronectin for in vivo activity |
Q45986472 | Bacteria hijack integrin-linked kinase to stabilize focal adhesions and block cell detachment. |
Q35216941 | Beta1 integrin cytoplasmic tyrosines promote skin tumorigenesis independent of their phosphorylation |
Q37137984 | Beta1 integrin deletion from the basal compartment of the mammary epithelium affects stem cells |
Q35227393 | Beta1 integrin establishes endothelial cell polarity and arteriolar lumen formation via a Par3-dependent mechanism |
Q36676760 | Beta1 integrin expression by podocytes is required to maintain glomerular structural integrity |
Q33441380 | Beta1 integrin-mediated adhesion signalling is essential for epidermal progenitor cell expansion |
Q28269425 | Beta1 integrins activate a MAPK signalling pathway in neural stem cells that contributes to their maintenance |
Q30486061 | Beta1 integrins differentially control extravasation of inflammatory cell subsets into the CNS during autoimmunity |
Q28508685 | Beta1 integrins regulate chondrocyte rotation, G1 progression, and cytokinesis |
Q36571060 | Beta1 integrins: zip codes and signaling relay for blood cells |
Q37475103 | Biological role of prolyl 3-hydroxylation in type IV collagen |
Q28512175 | Bral1: its role in diffusion barrier formation and conduction velocity in the CNS |
Q28511300 | Brevican-deficient mice display impaired hippocampal CA1 long-term potentiation but show no obvious deficits in learning and memory |
Q37166768 | CD98hc facilitates B cell proliferation and adaptive humoral immunity |
Q112301144 | CDK1-cyclin-B1-induced kindlin degradation drives focal adhesion disassembly at mitotic entry |
Q24537474 | Cartilage oligomeric matrix protein-deficient mice have normal skeletal development |
Q51442060 | Cell-Intrinsic Adaptation Arising from Chronic Ablation of a Key Rho GTPase Regulator. |
Q40234901 | Chondroitin sulfate perlecan enhances collagen fibril formation. Implications for perlecan chondrodysplasias |
Q39681478 | Chondromodulin I is dispensable during enchondral ossification and eye development |
Q54483880 | Comparative phenotypic analysis of the two major splice isoforms of phosphatidylinositol phosphate kinase type Iγ in vivo. |
Q44315309 | Complementary roles of glycoprotein VI and alpha2beta1 integrin in collagen-induced thrombus formation in flowing whole blood ex vivo |
Q52088676 | Conditional beta1-integrin gene deletion in neural crest cells causes severe developmental alterations of the peripheral nervous system. |
Q31021873 | Consequences of loss of PINCH2 expression in mice |
Q49644293 | Corrigendum: Fibronectin-bound α5β1 integrins sense load and signal to reinforce adhesion in less than a second |
Q38298213 | Cre recombinase induces DNA damage and tetraploidy in the absence of loxP sites |
Q28588278 | Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-kappaB signaling |
Q36324123 | Defective Rac-mediated proliferation and survival after targeted mutation of the beta1 integrin cytodomain |
Q42845718 | Defective granulation tissue formation in mice with specific ablation of integrin-linked kinase in fibroblasts - role of TGFβ1 levels and RhoA activity |
Q28585295 | Differential gene expression between sensory neocortical areas: potential roles for Ten_m3 and Bcl6 in patterning visual and somatosensory pathways |
Q57385104 | Differentiation of Embryonal Stem Cells into Keratinocytes: Comparison of Wild-Type and β1Integrin-Deficient Cells |
Q24324657 | Disruption of focal adhesions by integrin cytoplasmic domain-associated protein-1 alpha |
Q34130320 | Dissecting the molecular architecture of integrin adhesion sites by cryo-electron tomography |
Q30514206 | Distinct roles for talin-1 and kindlin-3 in LFA-1 extension and affinity regulation |
Q37061845 | Down-regulation of CYLD expression by Snail promotes tumor progression in malignant melanoma |
Q40549682 | Dystroglycan in skin and cutaneous cells: beta-subunit is shed from the cell surface |
Q36228711 | ESAM supports neutrophil extravasation, activation of Rho, and VEGF-induced vascular permeability |
Q28585722 | Elimination of epiplakin by gene targeting results in acceleration of keratinocyte migration in mice |
Q36149239 | Ena/VASP is required for endothelial barrier function in vivo |
Q28508460 | Endothelium-specific ablation of PDGFB leads to pericyte loss and glomerular, cardiac and placental abnormalities |
Q53600682 | Essential functions of Alk3 during AV cushion morphogenesis in mouse embryonic hearts. |
Q44508747 | Fibroblast growth factor receptor signalling is crucial for liver homeostasis and regeneration |
Q51812706 | Fibronectin is required for integrin alphavbeta6-mediated activation of latent TGF-beta complexes containing LTBP-1. |
Q47370705 | Fibronectin-bound α5β1 integrins sense load and signal to reinforce adhesion in less than a second |
Q46340921 | Formation and activation of fibroblast spheroids depend on fibronectin-integrin interaction |
Q48368670 | Functional inactivation of a fraction of excitatory synapses in mice deficient for the active zone protein bassoon |
Q39205680 | Functionalizing αvβ3- or α5β1-selective integrin antagonists for surface coating: a method to discriminate integrin subtypes in vitro |
Q37855339 | Genetic analyses of integrin signaling |
Q39741501 | Genetic analysis of beta1 integrin "activation motifs" in mice |
Q28586728 | Genomic organization of profilin-III and evidence for a transcript expressed exclusively in testis |
Q28512972 | Glycosylation catalyzed by lysyl hydroxylase 3 is essential for basement membranes |
Q47931618 | Guido Tarone, Ph.D. (1951-2015). |
Q44010133 | Homing of mouse spermatogonial stem cells to germline niche depends on beta1-integrin |
Q37533427 | How ILK and kindlins cooperate to orchestrate integrin signaling |
Q36403372 | ILK, PINCH and parvin: the tIPP of integrin signalling |
Q40014118 | Improvement of reporter activity by IRES-mediated polycistronic reporter system |
Q43565259 | In vivo SILAC-based proteomics reveals phosphoproteome changes during mouse skin carcinogenesis |
Q35846812 | Increased tumor cell dissemination and cellular senescence in the absence of beta1-integrin function |
Q54527822 | Induction of membrane circular dorsal ruffles requires co-signalling of integrin-ILK-complex and EGF receptor. |
Q42153207 | Insulin resistance in striated muscle-specific integrin receptor beta1-deficient mice |
Q90854393 | Integrin activation by talin, kindlin and mechanical forces |
Q39938242 | Integrin adhesion and force coupling are independently regulated by localized PtdIns(4,5)2 synthesis |
Q46803220 | Integrin beta1 subunit controls mural cell adhesion, spreading, and blood vessel wall stability |
Q39937866 | Integrin trafficking regulated by Rab21 is necessary for cytokinesis |
Q55056187 | Integrin-linked kinase at a glance. |
Q42066604 | Integrin-linked kinase controls microtubule dynamics required for plasma membrane targeting of caveolae |
Q42579182 | Integrin-linked kinase controls vascular wall formation by negatively regulating Rho/ROCK-mediated vascular smooth muscle cell contraction |
Q28261429 | Integrin-linked kinase is an adaptor with essential functions during mouse development |
Q30480583 | Integrin-linked kinase is required for epidermal and hair follicle morphogenesis |
Q28587844 | Integrin-linked kinase is required for radial sorting of axons and Schwann cell remyelination in the peripheral nervous system |
Q40771629 | Integrin-linked kinase regulates chondrocyte shape and proliferation |
Q42077991 | Integrin-linked kinase regulates p38 MAPK-dependent cell cycle arrest in ureteric bud development |
Q36491774 | Integrin-linked kinase stabilizes myotendinous junctions and protects muscle from stress-induced damage |
Q35885660 | Integrin-linked kinase: integrin's mysterious partner |
Q39016068 | Integrin-mediated mechanotransduction |
Q33944185 | Integrin-mediated type II TGF-β receptor tyrosine dephosphorylation controls SMAD-dependent profibrotic signaling |
Q51928095 | Integrins anchor the invasive machinery. |
Q37271595 | Integrins are required for the differentiation of visceral endoderm |
Q34603045 | Integrins in invasive growth |
Q38794531 | Integrins synergise to induce expression of the MRTF-A-SRF target gene ISG15 for promoting cancer cell invasion |
Q30830770 | Interactions with fibronectin attenuate the virulence of Streptococcus pyogenes |
Q38716553 | Introduction to the ECR special issue, "Mechanosensing via Cell-Matrix Adhesions". |
Q39466114 | Kank2 activates talin, reduces force transduction across integrins and induces central adhesion formation |
Q28507652 | Kindlin-2 controls bidirectional signaling of integrins |
Q38358692 | Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin |
Q40045183 | Kindlin-2 recruits paxillin and Arp2/3 to promote membrane protrusions during initial cell spreading. |
Q28595084 | Kindlin-3 is essential for integrin activation and platelet aggregation |
Q28507135 | Kindlin-3 is required for beta2 integrin-mediated leukocyte adhesion to endothelial cells |
Q30552379 | Kindlin-3 regulates integrin activation and adhesion reinforcement of effector T cells |
Q27308783 | Kindlin-3-mediated integrin adhesion is dispensable for quiescent but essential for activated hematopoietic stem cells |
Q42197118 | Kindlin-3-mediated signaling from multiple integrin classes is required for osteoclast-mediated bone resorption |
Q51733905 | Knockdown and knockout of β1-integrin in hepatocytes impairs liver regeneration through inhibition of growth factor signalling. |
Q40512860 | Laminin isoforms differentially regulate adhesion, spreading, proliferation, and ERK activation of beta1 integrin-null cells |
Q35705635 | Laminin: the crux of basement membrane assembly |
Q35622419 | Lentiviral transgene vectors |
Q33389852 | Loss of Kindlin-1 causes skin atrophy and lethal neonatal intestinal epithelial dysfunction |
Q34394834 | Loss of alpha10beta1 integrin expression leads to moderate dysfunction of growth plate chondrocytes |
Q51891549 | Loss of migfilin expression has no overt consequences on murine development and homeostasis. |
Q34726698 | Loss of talin1 in platelets abrogates integrin activation, platelet aggregation, and thrombus formation in vitro and in vivo |
Q36382181 | Loss of the Rap1 effector RIAM results in leukocyte adhesion deficiency due to impaired β2 integrin function in mice |
Q55171163 | Lucky kindlin: A cloverleaf at the integrin tail. |
Q36324592 | Matrix assembly, regulation, and survival functions of laminin and its receptors in embryonic stem cell differentiation |
Q37360853 | Mechanisms that regulate adaptor binding to beta-integrin cytoplasmic tails |
Q30505376 | Mechanoinduction of lymph vessel expansion |
Q26849684 | Mechanosensitivity and compositional dynamics of cell-matrix adhesions |
Q41965697 | Membrane tension drives ligand-independent integrin signaling |
Q60955777 | Microenvironment-derived ADAM28 prevents cancer dissemination |
Q28590384 | Mig6 is a negative regulator of EGF receptor-mediated skin morphogenesis and tumor formation |
Q40965315 | Minimal amounts of kindlin-3 suffice for basal platelet and leukocyte functions in mice |
Q44650514 | Modulation of Ca2+ sensitivity by cyclic nucleotides in smooth muscle from protein kinase G-deficient mice |
Q34269023 | Molecular cloning of Bral2, a novel brain-specific link protein, and immunohistochemical colocalization with brevican in perineuronal nets☆ |
Q42164315 | Molecular dissection of the ILK-PINCH-parvin triad reveals a fundamental role for the ILK kinase domain in the late stages of focal-adhesion maturation |
Q28508913 | Mutations in the paxillin-binding site of integrin-linked kinase (ILK) destabilize the pseudokinase domain and cause embryonic lethality in mice |
Q112645503 | Neutrophils direct preexisting matrix to initiate repair in damaged tissues |
Q28510333 | None of the integrins known to be present on the mouse egg or to be ADAM receptors are essential for sperm-egg binding and fusion |
Q33502785 | Nonviral in situ green fluorescent protein labeling and culture of primary, adult human hair follicle epithelial progenitor cells |
Q54486346 | PINCH-1 promotes Bcl-2-dependent survival signalling and inhibits JNK-mediated apoptosis in the primitive endoderm. |
Q33968025 | PINCH1 regulates Akt1 activation and enhances radioresistance by inhibiting PP1alpha |
Q28586746 | PINCH1 regulates cell-matrix and cell-cell adhesions, cell polarity and cell survival during the peri-implantation stage |
Q28589673 | PINCH2 is a new five LIM domain protein, homologous to PINCHand localized to focal adhesions |
Q30497801 | PIPKIγ90 Negatively Regulates LFA-1–Mediated Adhesion and Activation in Antigen-Induced CD4+ T Cells |
Q42254716 | Plasma fibronectin deficiency impedes atherosclerosis progression and fibrous cap formation |
Q30477630 | Plasma fibronectin promotes thrombus growth and stability in injured arterioles |
Q30487678 | Profilin 1 is required for abscission during late cytokinesis of chondrocytes |
Q39589743 | Profilin1 regulates sternum development and endochondral bone formation |
Q43232698 | Protein kinase G controls brown fat cell differentiation and mitochondrial biogenesis |
Q30482362 | Proteinase 3 and neutrophil elastase enhance inflammation in mice by inactivating antiinflammatory progranulin |
Q30498837 | Quantitative proteomics of the integrin adhesome show a myosin II-dependent recruitment of LIM domain proteins |
Q41782395 | Regulation of B cell homeostasis and activation by the tumor suppressor gene CYLD |
Q46975937 | Regulation of integrin activity by MIA. |
Q37858134 | Regulation of membrane traffic by integrin signaling |
Q28253861 | Regulation of neural progenitor proliferation and survival by beta1 integrins |
Q53906565 | Role of collagen type II and perlecan in skeletal development. |
Q46458771 | SILAC mouse for quantitative proteomics uncovers kindlin-3 as an essential factor for red blood cell function |
Q39227376 | Sensing the mechano-chemical properties of the extracellular matrix |
Q39860911 | Solid tumor proteome and phosphoproteome analysis by high resolution mass spectrometry |
Q38975551 | Sorting nexin 31 binds multiple β integrin cytoplasmic domains and regulates β1 integrin surface levels and stability |
Q30445390 | Staphylococcus aureus fibronectin binding protein-A induces motile attachment sites and complex actin remodeling in living endothelial cells |
Q47674930 | Talin regulates integrin β1-dependent and -independent cell functions in ureteric bud development |
Q34462862 | Targeted disruption of the murine zyxin gene |
Q27334204 | Ten_m3 regulates eye-specific patterning in the mammalian visual pathway and is required for binocular vision |
Q30979772 | Tenomodulin is necessary for tenocyte proliferation and tendon maturation |
Q57713422 | The Kank family proteins in adhesion dynamics |
Q37600289 | The Kindlin protein family: new members to the club of focal adhesion proteins |
Q28513797 | The Kindlins: subcellular localization and expression during murine development |
Q39743726 | The RGD motif in fibronectin is essential for development but dispensable for fibril assembly |
Q40344279 | The contribution of beta1 integrins to neuronal migration and differentiation depends on extracellular matrix molecules |
Q30441899 | The fibronectin-binding integrins alpha5beta1 and alphavbeta3 differentially modulate RhoA-GTP loading, organization of cell matrix adhesions, and fibronectin fibrillogenesis |
Q35126974 | The focal adhesion protein PINCH-1 associates with EPLIN at integrin adhesion sites |
Q38197886 | The integrin adhesome: from genes and proteins to human disease |
Q47692376 | The integrin coactivator Kindlin-3 is not required for lymphocyte diapedesis |
Q24676735 | The integrin-actin connection, an eternal love affair |
Q28077899 | The kindlin family: functions, signaling properties and implications for human disease |
Q37769018 | The kindlins at a glance |
Q37552184 | The mechanism of kindlin-mediated activation of integrin αIIbβ3. |
Q30818120 | The murine Ten-m/Odz genes show distinct but overlapping expression patterns during development and in adult brain |
Q37202232 | The role of integrin binding sites in fibronectin matrix assembly in vivo |
Q41610666 | The role of integrin-linked kinase in the molecular architecture of focal adhesions |
Q35123983 | The role of laminin in embryonic cell polarization and tissue organization |
Q46005089 | The stimulation of dendrite growth by Sema3A requires integrin engagement and focal adhesion kinase. |
Q37483142 | The tail of integrins, talin, and kindlins |
Q40308782 | The vascular basement membrane: a niche for insulin gene expression and Beta cell proliferation |
Q40331797 | Threonine 788 in integrin subunit beta1 regulates integrin activation |
Q52583362 | Trps1 regulates proliferation and apoptosis of chondrocytes through Stat3 signaling. |
Q28511662 | Type IX collagen knock-out mouse shows progressive hearing loss |
Q28591920 | Ultrastructural cartilage abnormalities in MIA/CD-RAP-deficient mice |
Q45964944 | Versican V2 assembles the extracellular matrix surrounding the nodes of ranvier in the CNS. |
Q39807801 | beta1 integrin is necessary for ureteric bud branching morphogenesis and maintenance of collecting duct structural integrity |
Q46482139 | beta1 integrins are not required for the maintenance of lymphocytes within intestinal epithelia |
Q42124473 | gamma-Parvin is dispensable for hematopoiesis, leukocyte trafficking, and T-cell-dependent antibody response |
Q33809470 | β1 integrin signaling promotes neuronal migration along vascular scaffolds in the post-stroke brain |
Q42519298 | β1 integrins with individually disrupted cytoplasmic NPxY motifs are embryonic lethal but partially active in the epidermis |
Q39147447 | β1- and αv-class integrins cooperate to regulate myosin II during rigidity sensing of fibronectin-based microenvironments |
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