Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression

scientific journal article

Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.4049/JIMMUNOL.177.10.7303
P3181OpenCitations bibliographic resource ID721315
P698PubMed publication ID17082649
P5875ResearchGate publication ID6713621

P50authorAlberto MantovaniQ22069468
Siamon GordonQ7506761
P2093author name stringMassimo Locati
Fernando O. Martinez
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectmacrophageQ184204
P304page(s)7303–7311
P577publication date2006-11-15
P1433published inJournal of ImmunologyQ3521441
P1476titleTranscriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression
P478volume177

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cites work (P2860)
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Q50088162Galectin-3 Interacts with the CHI3L1 Axis and Contributes to Hermansky-Pudlak Syndrome Lung Disease.
Q89587251Gastric Tumor Microenvironment
Q52408795Gene Network Analysis of Interstitial Macrophages After Treatment with Induced Pluripotent Stem Cells Secretome (iPSC-cm) in the Bleomycin Injured Rat Lung.
Q38344215Gene expression profiling of PBMCs from Holstein and Jersey cows sub-clinically infected with Mycobacterium avium ssp. paratuberculosis.
Q35649056Gene expression profiling of cutaneous wound healing
Q36570240Gene expression profiling of human decidual macrophages: evidence for immunosuppressive phenotype
Q50672047Gene expression profiling of peripheral blood from patients with untreated new-onset systemic juvenile idiopathic arthritis reveals molecular heterogeneity that may predict macrophage activation syndrome.
Q27319245Gene expression study of monocytes/macrophages during early foreign body reaction and identification of potential precursors of myofibroblasts
Q37360466Gene profiling of human adipose tissue during evoked inflammation in vivo
Q35752331Genetic and Informatic Analyses Implicate Kif12 as a Candidate Gene within the Mpkd2 Locus That Modulates Renal Cystic Disease Severity in the Cys1cpk Mouse
Q37087622Genome-wide innate immune responses in HIV-1-infected macrophages are preserved despite attenuation of the NF-kappa B activation pathway
Q34992223Germline CYBB mutations that selectively affect macrophages in kindreds with X-linked predisposition to tuberculous mycobacterial disease
Q36835712Ginsenoside Rd alleviates mouse acute renal ischemia/reperfusion injury by modulating macrophage phenotype
Q38206485Glial scar and immune cell involvement in tissue remodeling and repair following acute CNS injuries
Q58785727Glioblastoma Recurrence Correlates With Increased APE1 and Polarization Toward an Immuno-Suppressive Microenvironment
Q38868808Glioblastoma-infiltrated innate immune cells resemble M0 macrophage phenotype
Q34165688Global gene expression profiles of canine macrophages and canine mammary cancer cells grown as a co-culture in vitro
Q34171422Global transcriptional analysis for biomarker discovery and validation in cellular therapies
Q38673357Glucocorticoid-induced leucine zipper (GILZ) in immuno suppression: master regulator or bystander?
Q92451047Glycation of macrophages induces expression of pro-inflammatory cytokines and reduces phagocytic efficiency
Q34257399Glycosyltransferase and sulfotransferase gene expression profiles in human monocytes, dendritic cells and macrophages.
Q42107942Gr1+ Macrophages and Dendritic Cells Dominate the Inflammatory Infiltrate 12 Hours After Experimental Intracerebral Hemorrhage
Q37635119Granulocyte Macrophage Colony-Stimulating Factor-Activated CD39+/CD73+ Murine Monocytes Modulate Intestinal Inflammation via Induction of Regulatory T Cells
Q55277536Granulocyte-Derived Extracellular Vesicles Activate Monocytes and Are Associated With Mortality in Intensive Care Unit Patients.
Q34700042Granulomatous response to Coxiella burnetii, the agent of Q fever: the lessons from gene expression analysis
Q37612267Group V secretory phospholipase A2 is involved in macrophage activation and is sufficient for macrophage effector functions in allergic pulmonary inflammation.
Q41943813Guanylate-binding protein 5 is a marker of interferon-γ-induced classically activated macrophages
Q33868782HDL promotes rapid atherosclerosis regression in mice and alters inflammatory properties of plaque monocyte-derived cells
Q62604186HER2 signaling regulates the tumor immune microenvironment and trastuzumab efficacy
Q39138504HIV-1 Nef interacts with HCV Core, recruits TRAF2, TRAF5 and TRAF6, and stimulates HIV-1 replication in macrophages.
Q33865132HIV-1 infection of macrophages is dependent on evasion of innate immune cellular activation
Q39027389HIV-1-Mediated BAFF Secretion in Macrophages Does Not Require Endosomal TLRs, Type-I IFN, and Nef, but Depends on the Cellular Phenotype Status.
Q38830051HMGB1 enhances the protumoral activities of M2 macrophages by a RAGE-dependent mechanism
Q42321775Harvesting pre-polarized macrophages using thermo-responsive substrates
Q35378767Hck is a key regulator of gene expression in alternatively activated human monocytes
Q35039330Hematopoietic Akt2 deficiency attenuates the progression of atherosclerosis
Q37296716Hepatitis C Virus-Induced Monocyte Differentiation Into Polarized M2 Macrophages Promotes Stellate Cell Activation via TGF-β
Q89892776Herpes simplex virus type 1 inflammasome activation in proinflammatory human macrophages is dependent on NLRP3, ASC, and caspase-1
Q48178555Heterogeneous effects of M-CSF isoforms on the progression of MLL-AF9 leukemia.
Q49323705High-Resolution Mapping and Dynamics of the Transcriptome, Transcription Factors, and Transcription Co-Factor Networks in Classically and Alternatively Activated Macrophages.
Q34429127High-resolution transcriptome of human macrophages
Q39045908Histamine induces chemotaxis and phagocytosis in murine bone marrow-derived macrophages and RAW 264.7 macrophage-like cells via histamine H4-receptor
Q41172414Histone deacetylase 5 regulates the inflammatory response of macrophages
Q99237959Host-Directed Therapy in Tuberculosis: Targeting Host Metabolism
Q53433078Human Amniotic Membrane-Derived Mesenchymal and Epithelial Cells Exert Different Effects on Monocyte-Derived Dendritic Cell Differentiation and Function.
Q42359964Human Mesenchymal stem cells program macrophage plasticity by altering their metabolic status via a PGE2-dependent mechanism
Q33418607Human TRIM gene expression in response to interferons
Q64112523Human Tumor-Associated Macrophage and Monocyte Transcriptional Landscapes Reveal Cancer-Specific Reprogramming, Biomarkers, and Therapeutic Targets
Q39362988Human adipose tissue macrophages display activation of cancer-related pathways
Q42531590Human cytomegalovirus infection of M1 and M2 macrophages triggers inflammation and autologous T-cell proliferation.
Q39300711Human cytomegalovirus infection of THP-1 derived macrophages reveals strain-specific regulation of actin dynamics
Q37123220Human cytomegalovirus interleukin-10 polarizes monocytes toward a deactivated M2c phenotype to repress host immune responses
Q61797089Human macrophages survive and adopt activated genotypes in living zebrafish
Q40920077Human mesenchymal stem cells alter the gene profile of monocytes from patients with Type 2 diabetes and end-stage renal disease.
Q41417120Human mesenchymal stromal cell-secreted lactate induces M2-macrophage differentiation by metabolic reprogramming
Q34596015Human monocyte subsets at homeostasis and their perturbation in numbers and function in filarial infection
Q36018901Human newborn bacille Calmette-Guérin vaccination and risk of tuberculosis disease: a case-control study
Q39575333Human trophoblast-derived exosomal fibronectin induces pro-inflammatory IL-1β production by macrophages
Q49725890Hypoxia Pathway Proteins As Central Mediators of Metabolism in the Tumor Cells and Their Microenvironment.
Q36673682IFN-γ-induced iNOS expression in mouse regulatory macrophages prolongs allograft survival in fully immunocompetent recipients
Q42373352IFNγ Enhances CD64-Potentiated Phagocytosis of Treponema pallidum Opsonized with Human Syphilitic Serum by Human Macrophages
Q33910916IGF1 Shapes Macrophage Activation in Response to Immunometabolic Challenge
Q90350370IGF1 Treatment Improves Cardiac Remodeling after Infarction by Targeting Myeloid Cells
Q34576044IGFBP-3 inhibits cytokine-induced insulin resistance and early manifestations of atherosclerosis
Q34774059IL-10 cytokine released from M2 macrophages is crucial for analgesic and anti-inflammatory effects of acupuncture in a model of inflammatory muscle pain
Q42505206IL-10 expression in macrophages from neonates born from obese mothers is suppressed by IL-4 and LPS/INFγ.
Q34364890IL-17A influences essential functions of the monocyte/macrophage lineage and is involved in advanced murine and human atherosclerosis.
Q49303424IL-34 and CSF-1 display an equivalent macrophage differentiation ability but a different polarization potential.
Q43057759IL-34 and M-CSF share the receptor Fms but are not identical in biological activity and signal activation.
Q24317213IL-34 induces the differentiation of human monocytes into immunosuppressive macrophages. antagonistic effects of GM-CSF and IFNγ
Q39253966IL-36γ/IL-1F9, an innate T-bet target in myeloid cells.
Q37246528IL-4 directly signals tissue-resident macrophages to proliferate beyond homeostatic levels controlled by CSF-1
Q40144941IL-4 up-regulates cyclooxygenase-1 expression in macrophages.
Q57138348IL-6 augments IL-4-induced polarization of primary human macrophages through synergy of STAT3, STAT6 and BATF transcription factors
Q90504443IL-6 produced by prostate epithelial cells stimulated with Trichomonas vaginalis promotes proliferation of prostate cancer cells by inducing M2 polarization of THP-1-derived macrophages
Q42799118IRF2BP2: A New Player at the Crossroads of Inflammation and Lipid Metabolism
Q64376801IRF5 Is a Key Regulator of Macrophage Response to Lipopolysaccharide in Newborns
Q37513344IRF5 and IRF5 Disease-Risk Variants Increase Glycolysis and Human M1 Macrophage Polarization by Regulating Proximal Signaling and Akt2 Activation
Q28303437IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses
Q37969227Identification and manipulation of tumor associated macrophages in human cancers
Q37620348Identification of Pathway-Specific Serum Biomarkers of Response to Glucocorticoid and Infliximab Treatment in Children with Inflammatory Bowel Disease
Q91995799Identification of TNFR2 and IL-33 as therapeutic targets in localized fibrosis
Q60301328Identification of alterations in macrophage activation associated with disease activity in systemic lupus erythematosus
Q37714302Identification of an atypical etiological head and neck squamous carcinoma subtype featuring the CpG island methylator phenotype
Q37708958Identification of distinct monocyte phenotypes and correlation with circulating cytokine profiles in acute response to spinal cord injury: a pilot study.
Q35060742Identification of miR-30e* regulation of Bmi1 expression mediated by tumor-associated macrophages in gastrointestinal cancer
Q90571127Identification of new molecular targets for PET imaging of the microglial anti-inflammatory activation state
Q35906920Identification of polarized macrophage subsets in zebrafish
Q90250087Identification of stable reference genes for lipopolysaccharide-stimulated macrophage gene expression studies
Q36052406Identifying functional microRNAs in macrophages with polarized phenotypes
Q50217783Immune Cell Metabolism in Tumor Microenvironment.
Q26765855Immune Evasion Strategies of Glioblastoma
Q38197678Immune mediators as potential diagnostic tools for colorectal cancer: from experimental rationale to early clinical evidence
Q26796857Immune phenotypes of microglia in human neurodegenerative disease: challenges to detecting microglial polarization in human brains
Q35370785Immunolabeling of gamma-glutamyl transferase 5 in normal human tissues reveals that expression and localization differ from gamma-glutamyl transferase 1
Q27021247Immunometabolism in Tuberculosis
Q37235370Immunometabolism in obese asthmatics: are we there yet?
Q92768544Immunometabolism: A new target for improving cancer immunotherapy
Q52370784Immunomodulatory and Inhibitory Effect of Immulina®, and Immunloges® in the Ig-E Mediated Activation of RBL-2H3 Cells. A New Role in Allergic Inflammatory Responses.
Q64974331Immunomodulatory nanodiamond aggregate-based platform for the treatment of rheumatoid arthritis.
Q38403174Immunopathology of chronic rhinosinusitis.
Q35223657Impact of azithromycin treatment on macrophage gene expression in subjects with cystic fibrosis
Q64039792Impact of constitutional TET2 haploinsufficiency on molecular and clinical phenotype in humans
Q40469488Impact of individual intravenous iron preparations on the differentiation of monocytes towards macrophages and dendritic cells.
Q64056390Impaired cellular energy metabolism in cord blood macrophages contributes to abortive response toward inflammatory threats
Q40836532Impairment of Immunoproteasome Function by Cigarette Smoke and in Chronic Obstructive Pulmonary Disease
Q92128420Improved cell composition deconvolution method of bulk gene expression profiles to quantify subsets of immune cells
Q35626184In vitro and in vivo anticancer activity of a synthetic glycolipid as Toll-like receptor 4 (TLR4) activator
Q28394927In vitro inflammatory effects of hard metal (WC-Co) nanoparticle exposure
Q42384741In vitro response of macrophages to ceramic scaffolds used for bone regeneration
Q34428953In vivo inhibition of c-MYC in myeloid cells impairs tumor-associated macrophage maturation and pro-tumoral activities.
Q51386372Increased FcγRIIB dominance contributes to the emergence of resistance to therapeutic antibodies in chronic lymphocytic leukaemia patients.
Q35634156Increased expression of CC chemokine ligand 18 in patients with chronic rhinosinusitis with nasal polyps.
Q33808154Increased expression of macrophage-inducible C-type lectin in adipose tissue of obese mice and humans
Q35085607Increased expression of the chemokine CCL23 in eosinophilic chronic rhinosinusitis with nasal polyps
Q34399073Increased microglia/macrophage gene expression in a subset of adult and pediatric astrocytomas
Q36339378Inducible renitence limits Listeria monocytogenes escape from vacuoles in macrophages.
Q37727856Induction of M2-like macrophages in recipient NOD-scid mice by allogeneic donor CD4(+)CD25(+) regulatory T cells
Q35015735Induction of microRNAs, mir-155, mir-222, mir-424 and mir-503, promotes monocytic differentiation through combinatorial regulation
Q28083186Infection homeostasis: implications for therapeutic and immune programming of metabolism in controlling infection
Q94547046Infection of Monocytes From Tuberculosis Patients With Two Virulent Clinical Isolates of Mycobacterium tuberculosis Induces Alterations in Myeloid Effector Functions
Q36943794Inflammation activation and resolution in human tendon disease
Q38083555Inflammation and immune system interactions in atherosclerosis
Q48083290Inflammation and macrophage polarization in cutaneous melanoma: Histopathological and immunohistochemical study.
Q42611487Inflammatory and alternatively activated human macrophages attract vessel-associated stem cells, relying on separate HMGB1- and MMP-9-dependent pathways
Q34487229Inflammatory expression profiles in monocyte-to-macrophage differentiation in patients with systemic lupus erythematosus and relationship with atherosclerosis.
Q49788145Inflammatory macrophage-associated 3-gene signature predicts subclinical allograft injury and graft survival.
Q34283413Inflammatory monocytes determine endothelial nitric-oxide synthase uncoupling and nitro-oxidative stress induced by angiotensin II
Q34125085Influenza virus A infection of human monocyte and macrophage subpopulations reveals increased susceptibility associated with cell differentiation.
Q37737112Inhibition of atherogenesis by the COP9 signalosome subunit 5 in vivo.
Q45913402Inhibition of intimal hyperplasia in murine aortic allografts by administration of a small-molecule TLR4 inhibitor TAK-242.
Q40952628Inhibition of vacuolar ATPase subunit in tumor cells delays tumor growth by decreasing the essential macrophage population in the tumor microenvironment
Q52666797Inhibitor of apoptosis proteins, NAIP, cIAP1 and cIAP2 expression during macrophage differentiation and M1/M2 polarization.
Q57599442Innate Immunity in the CNS - A Focus on the Myeloid Cell
Q42268758Innate immune pathways in afferent lymph following vaccination with poly(I:C)-containing liposomes.
Q34980214Innate immunity and monocyte-macrophage activation in atherosclerosis.
Q40142055Integrated Transcriptomics Establish Macrophage Polarization Signatures and have Potential Applications for Clinical Health and Disease
Q31144077Integrated expression profiles of mRNA and miRNA in polarized primary murine microglia
Q38686210Integrated regulation of the cellular metabolism and function of immune cells in adipose tissue
Q62488559Interaction between inflammation and angiogenesis during different stages of cervical carcinogenesis
Q40579361Interaction studies reveal specific recognition of an anti-inflammatory polyphosphorhydrazone dendrimer by human monocytes
Q34059742Interferon alpha treatment of patients with impaired interferon gamma signaling
Q33649222Interferon and alternative activation of monocyte/macrophages in systemic sclerosis-associated pulmonary arterial hypertension.
Q37193358Interferon regulatory factor 4 regulates obesity-induced inflammation through regulation of adipose tissue macrophage polarization
Q28486504Interferon-beta induces distinct gene expression response patterns in human monocytes versus T cells
Q30413069Interferon-induced HERC5 is evolving under positive selection and inhibits HIV-1 particle production by a novel mechanism targeting Rev/RRE-dependent RNA nuclear export
Q27012493Interferon-regulatory factors determine macrophage phenotype polarization
Q92549590Interleukin 4: Its Role in Hypertension, Atherosclerosis, Valvular, and Nonvalvular Cardiovascular Diseases
Q35884586Interleukin-10 receptor signaling in innate immune cells regulates mucosal immune tolerance and anti-inflammatory macrophage function
Q54650095Interleukin-25 fails to activate STAT6 and induce alternatively activated macrophages.
Q33722773Interleukin-33 contributes to both M1 and M2 chemokine marker expression in human macrophages
Q30802553Interleukin-4 Expressed By Neoplastic Cells Provokes an Anti-Metastatic Myeloid Immune Response
Q36711467Interleukin-4- and interleukin-13-mediated alternatively activated macrophages: roles in homeostasis and disease.
Q36380638Interleukin-6 stimulates Akt and p38 MAPK phosphorylation and fibroblast migration in non-diabetic but not diabetic mice
Q90002498Interplay of Autophagy Inducer Rapamycin and Proteasome Inhibitor MG132 in Reduction of Foam Cell Formation and Inflammatory Cytokine Expression
Q34962285Intracellular survival and persistence of Chlamydia muridarum is determined by macrophage polarization
Q60952913Involvement of M1 Macrophage Polarization in Endosomal Toll-Like Receptors Activated Psoriatic Inflammation
Q39652862Involvement of M2-polarized macrophages in the ascites from advanced epithelial ovarian carcinoma in tumor progression via Stat3 activation
Q44729879In vitro model to study the biomaterial-dependent reaction of macrophages in an inflammatory environment.
Q36433820Ionizing radiation modulates human macrophages towards a pro-inflammatory phenotype preserving their pro-invasive and pro-angiogenic capacities
Q37668863Iron Reduces M1 Macrophage Polarization in RAW264.7 Macrophages Associated with Inhibition of STAT1.
Q21090792Iron is a sensitive biomarker for inflammation in multiple sclerosis lesions
Q38898354Is Synovial Macrophage Activation the Inflammatory Link Between Obesity and Osteoarthritis?
Q52921508Isolation and Differentiation of Human Macrophages.
Q93246994Isolation and characterization of ovine monocyte-derived macrophages from peripheral blood
Q40045045Isolation of human monocytes by double gradient centrifugation and their differentiation to macrophages in teflon-coated cell culture bags.
Q39828591Ixmyelocel-T, an expanded multicellular therapy, contains a unique population of M2-like macrophages
Q33940685IκB kinase activity drives fetal lung macrophage maturation along a non-M1/M2 paradigm.
Q42778549JAK2 Disease-Risk Variants Are Gain of Function and JAK Signaling Threshold Determines Innate Receptor-Induced Proinflammatory Cytokine Secretion in Macrophages
Q37679296Large-scale chondroitin sulfate proteoglycan digestion with chondroitinase gene therapy leads to reduced pathology and modulates macrophage phenotype following spinal cord contusion injury
Q82928203Leishmania-induced repression of selected non-coding RNA genes containing B-box element at their promoters in alternatively polarized M2 macrophages
Q36715966Lenalidomide interferes with tumor-promoting properties of nurse-like cells in chronic lymphocytic leukemia.
Q47152127Lentinula edodes β-glucan enriched diet induces pro- and anti-inflammatory macrophages in rabbit.
Q38147032Lessons from developmental biology for regenerative medicine
Q38187169Linking obesity and asthma
Q91639049Lipid Metabolic Pathways Confer the Immunosuppressive Function of Myeloid-Derived Suppressor Cells in Tumor
Q37996954Lipid homeostasis and the formation of macrophage-derived foam cells in atherosclerosis
Q40441909Lipid profiling of polarized human monocyte-derived macrophages
Q64079898Lipopolysaccharide inhalation recruits monocytes and dendritic cell subsets to the alveolar airspace
Q37583613Low molecular weight hyaluronan activates cytosolic phospholipase A2α and eicosanoid production in monocytes and macrophages.
Q40368043Low shear stress induces M1 macrophage polarization in murine thin-cap atherosclerotic plaques
Q47649630M-CSF induces the expression of a membrane-bound form of IL-18 in a subset of human monocytes differentiating in vitro toward macrophages
Q48327546M1 Means Kill; M2 Means Heal.
Q27024667M1 and M2 immune activation in Parkinson's Disease: Foe and ally?
Q35740199M1 and M2 macrophages derived from THP-1 cells differentially modulate the response of cancer cells to etoposide
Q35600855M1 and M2 macrophages: the chicken and the egg of immunity
Q91830416M1-like macrophages are potent producers of anti-viral interferons and M1-associated marker-positive lung macrophages are decreased during rhinovirus-induced asthma exacerbations
Q38494724M1/M2 macrophages and associated mechanisms in congenital bicuspid aortic valve stenosis
Q35206084M2 polarization enhances silica nanoparticle uptake by macrophages
Q90696571M2b macrophage polarization and its roles in diseases
Q42324194M3 Macrophages Stop Division of Tumor Cells In Vitro and Extend Survival of Mice with Ehrlich Ascites Carcinoma
Q42652443MKL1 expressed in macrophages contributes to the development of murine colitis
Q38711882MS4A4A: a novel cell surface marker for M2 macrophages and plasma cells
Q92987345MST1R kinase accelerates pancreatic cancer progression via effects on both epithelial cells and macrophages
Q36362871Macrophage Blockade Using CSF1R Inhibitors Reverses the Vascular Leakage Underlying Malignant Ascites in Late-Stage Epithelial Ovarian Cancer
Q36591118Macrophage Infiltration and Alternative Activation during Wound Healing Promote MEK1-Induced Skin Carcinogenesis
Q38678295Macrophage Involvement in Systemic Sclerosis: Do We Need More Evidence?
Q35811018Macrophage Migration and Its Regulation by CSF-1
Q37978620Macrophage Phenotype Modulation by CXCL4 in Atherosclerosis
Q30359036Macrophage Polarization Modulates FcγR- and CD13-Mediated Phagocytosis and Reactive Oxygen Species Production, Independently of Receptor Membrane Expression.
Q37630894Macrophage activation and polarization in post-infarction cardiac remodeling
Q37812085Macrophage and dendritic cell phenotypic diversity in the context of biomaterials
Q45282568Macrophage colony-stimulating factor plays a pivotal role in chemically induced hepatocellular carcinoma in mice
Q38008842Macrophage differentiation and function in atherosclerosis: opportunities for therapeutic intervention?
Q34937306Macrophage diversity in cardiac inflammation: a review
Q36955562Macrophage diversity in renal injury and repair.
Q30273952Macrophage epoxygenase determines a profibrotic transcriptome signature
Q60922651Macrophage ferroportin is essential for stromal cell proliferation in wound healing
Q57420146Macrophage gene expression is related to obesity and the metabolic syndrome in human subcutaneous fat as well as in visceral fat
Q26996732Macrophage heterogeneity and acute inflammation
Q39246963Macrophage heterogeneity and cholesterol homeostasis: classically-activated macrophages are associated with reduced cholesterol accumulation following treatment with oxidized LDL.
Q37594434Macrophage heterogeneity in atherosclerotic plaques
Q38844780Macrophage heterogeneity in the context of rheumatoid arthritis.
Q33584709Macrophage phenotype and remodeling outcomes in response to biologic scaffolds with and without a cellular component
Q34240471Macrophage phenotype as a predictor of constructive remodeling following the implantation of biologically derived surgical mesh materials.
Q38260570Macrophage phenotypes in atherosclerosis.
Q29614349Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm
Q29547620Macrophage plasticity and polarization: in vivo veritas
Q37665065Macrophage polarization and HIV-1 infection.
Q37993741Macrophage polarization and plasticity in health and disease
Q27027054Macrophage polarization in health and disease
Q37140611Macrophage polarization in interstitial lung diseases
Q36591717Macrophage polarization in metabolic disorders: functions and regulation
Q42920879Macrophage polarization in response to wear particles in vitro.
Q34115375Macrophage polarization to a unique phenotype driven by B cells.
Q36717573Macrophage scavenger receptor a promotes tumor progression in murine models of ovarian and pancreatic cancer
Q38264834Macrophage subsets in atherosclerosis.
Q49165366Macrophage-Bacteria Interactions-A Lipid-Centric Relationship.
Q35571726Macrophage-elicited loss of estrogen receptor-α in breast cancer cells via involvement of MAPK and c-Jun at the ESR1 genomic locus.
Q58740853Macrophage-secreted interleukin-35 regulates cancer cell plasticity to facilitate metastatic colonization
Q37955105Macrophage-tumor crosstalk: role of TAMR tyrosine kinase receptors and of their ligands.
Q35107451Macrophage/epithelium cross-talk regulates cell cycle progression and migration in pancreatic progenitors
Q27027100Macrophage: SHIP of Immunity
Q26774649Macrophages During the Fibrotic Process: M2 as Friend and Foe
Q36694999Macrophages and Iron Metabolism
Q39271642Macrophages and Their Contribution to the Development of Atherosclerosis
Q38680703Macrophages and pancreatic ductal adenocarcinoma
Q35087352Macrophages at the fork in the road to health or disease
Q40138821Macrophages commit postnatal endothelium-derived progenitors to angiogenesis and restrict endothelial to mesenchymal transition during muscle regeneration.
Q39443058Macrophages in age-related chronic inflammatory diseases
Q37945300Macrophages in cancer and infectious diseases: the 'good' and the 'bad'.
Q36942573Macrophages in malignant pleural effusions - alternatively activated tumor associated macrophages.
Q92598413Macrophages induce malignant traits in mammary epithelium via IKKε/TBK1 kinases and the serine biosynthesis pathway
Q36040528Macrophages mediate cardioprotective cellular postconditioning in acute myocardial infarction
Q42559583Macrophages modulate engineered human tissues for enhanced vascularization and healing
Q39295052Macrophages modulate the viability and growth of human mesenchymal stem cells
Q56942176Macrophages, Neutrophils, and Cancer: A Double Edged Sword
Q48598698Macrophages: Their role, activation and polarization in pulmonary diseases.
Q38990423Macropinocytosis and TAK1 mediate anti-inflammatory to pro-inflammatory macrophage differentiation by HIV-1 Nef
Q60253988Magnetic Resonance Imaging of Tumor-Associated Macrophages: Clinical Translation
Q89965611Magnolol Attenuates Cisplatin-Induced Muscle Wasting by M2c Macrophage Activation
Q56364525Malaria parasite-mediated alteration of macrophage function and increased iron availability predispose to disseminated non-typhoidal infection
Q37323335Managing inflammation after spinal cord injury through manipulation of macrophage function
Q28478285Mannose receptor (MR) engagement by mesothelin GPI anchor polarizes tumor-associated macrophages and is blocked by anti-MR human recombinant antibody
Q52881850Mass cytometry deep phenotyping of human mononuclear phagocytes and myeloid-derived suppressor cells from human blood and bone marrow.
Q40059643Maternal Pregravid Obesity Remodels the DNA Methylation Landscape of Cord Blood Monocytes Disrupting Their Inflammatory Program
Q91638252Mechanism of Xu Li's Experiential Prescription for the Treatment of EGFR-Positive NSCLC
Q27003907Mechanisms driving macrophage diversity and specialization in distinct tumor microenvironments and parallelisms with other tissues
Q30353324Membrane-Tethered MUC1 Mucin Counter-Regulates the Phagocytic Activity of Macrophages.
Q88574913Mesenchymal Stem Cell-Macrophage Choreography Supporting Spinal Cord Repair
Q34429538Mesenchymal stem cell 1 (MSC1)-based therapy attenuates tumor growth whereas MSC2-treatment promotes tumor growth and metastasis
Q42253863Mesenchymal stem cell-educated macrophages: a novel type of alternatively activated macrophages
Q61804423Mesenchymal stem cells and the neuronal microenvironment in the area of spinal cord injury
Q39888503Mesenchymal stromal cells induce peculiar alternatively activated macrophages capable of dampening both innate and adaptive immune responses.
Q92538680Meta-Analysis of in vitro-Differentiated Macrophages Identifies Transcriptomic Signatures That Classify Disease Macrophages in vivo
Q40348070Metabolic Alterations Contribute to Enhanced Inflammatory Cytokine Production in Irgm1-deficient Macrophages
Q34316035Metabolic dysfunction drives a mechanistically distinct proinflammatory phenotype in adipose tissue macrophages
Q64100293Metabolic programming of macrophage functions and pathogens control
Q50062519Metabolic regulation of macrophage phenotype and function.
Q36342281Methylome of fetal and maternal monocytes and macrophages at the feto-maternal interface
Q42112188Mice deficient in N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase exhibit enhanced liver fibrosis and delayed recovery from fibrosis in carbon tetrachloride-treated mice
Q41855099MicroRNA let-7c regulates macrophage polarization.
Q38823315MicroRNA regulation of macrophages in human pathologies
Q64105081MicroRNAs as Molecular Switches in Macrophage Activation
Q36547119MicroRNAs in immune response and macrophage polarization.
Q47749757Microarray and bioinformatics analyses of gene expression profiles in BALB/c murine macrophage polarization
Q36399682Microglia in the TBI brain: The good, the bad, and the dysregulated.
Q37809665Microglia: key innate immune cells of the brain
Q38815779Microglial phenotypes in Parkinson's disease and animal models of the disease
Q46095501Microglial polarization and plasticity: evidence from organotypic hippocampal slice cultures.
Q38222590Mitochondrial metabolism, reactive oxygen species, and macrophage function-fishing for insights
Q51107478Modular analysis of bioinformatics demonstrates a critical role for NF-κB in macrophage activation.
Q90671325Modulating Bone Marrow Hematopoietic Lineage Potential to Prevent Bone Metastasis in Breast Cancer
Q35987094Modulation of Macrophage Polarization and HMGB1-TLR2/TLR4 Cascade Plays a Crucial Role for Cardiac Remodeling in Senescence-Accelerated Prone Mice.
Q34053962Modulation of TNF-induced macrophage polarization by synovial fibroblasts.
Q40353747Modulation of actin dynamics as potential macrophage subtype-targeting anti-tumour strategy
Q46368288Modulation of chitotriosidase during macrophage differentiation.
Q38029063Modulation of maternal immune system during pregnancy in the cow.
Q26774265Modulators of Macrophage Polarization Influence Healing of the Infarcted Myocardium
Q47563785Module Analysis Captures Pancancer Genetically and Epigenetically Deregulated Cancer Driver Genes for Smoking and Antiviral Response.
Q59808665Molecular Interactions Between Innate and Adaptive Immune Cells in Chronic Lymphocytic Leukemia and Their Therapeutic Implications
Q38315760Molecular definition of the pro-tumorigenic phenotype of glioma-activated microglia.
Q34787288Molecular mechanism for adiponectin-dependent M2 macrophage polarization: link between the metabolic and innate immune activity of full-length adiponectin
Q35552765Molecular phenotype of monocytes at the maternal-fetal interface
Q40990401Molecular profiling of long-term survivors identifies a subgroup of glioblastoma characterized by chromosome 19/20 co-gain
Q38710906Monitoring Cell-surface N-Glycoproteome Dynamics by Quantitative Proteomics Reveals Mechanistic Insights into Macrophage Differentiation.
Q35688305Monoamine oxidase A (MAO-A): a signature marker of alternatively activated monocytes/macrophages
Q35611467Monocyte and M1 Macrophage-induced Barrier Defect Contributes to Chronic Intestinal Inflammation in IBD.
Q37890185Monocyte and macrophage dynamics during atherogenesis
Q33805166Monocyte differentiation and macrophage priming are regulated differentially by pentraxins and their ligands
Q91676497Monocyte heterogeneity and functions in cancer
Q41874855Monocyte polarization: the relationship of genome-wide changes in H4 acetylation with polarization.
Q37424686Monocyte urokinase-type plasminogen activator up-regulation reduces thrombus size in a model of venous thrombosis.
Q37688255Monocyte-derived factors including PLA2G7 induced by macrophage-nasopharyngeal carcinoma cell interaction promote tumor cell invasiveness
Q34635263Monocyte-derived macrophages do not explain susceptibility to pulmonary non-tuberculous mycobacterial disease
Q35922338Monocyte-to-macrophage differentiation: synthesis and secretion of a complex extracellular matrix
Q36756794Monocyte/Macrophage-derived IGF-1 Orchestrates Murine Skeletal Muscle Regeneration and Modulates Autocrine Polarization
Q39271596Monocyte/Macrophage: NK Cell Cooperation-Old Tools for New Functions
Q36981636Monocytes and macrophages in tissue repair: Implications for immunoregenerative biomaterial design
Q38640912Morphologic, phenotypic, and transcriptomic characterization of classically and alternatively activated canine blood-derived macrophages in vitro
Q44106304Multi-platform 'Omics Analysis of Human Ebola Virus Disease Pathogenesis
Q37199818Murine Alveolar Macrophages Are Highly Susceptible to Replication of Coxiella burnetii Phase II In Vitro
Q33848355Mycobacteria induce TPL-2 mediated IL-10 in IL-4-generated alternatively activated macrophages
Q38134246Myeloid cells in atherosclerosis: a delicate balance of anti-inflammatory and proinflammatory mechanisms
Q39364012Myeloperoxidase-Oxidized LDLs Enhance an Anti-Inflammatory M2 and Antioxidant Phenotype in Murine Macrophages.
Q37329260NF-kappaB and phosphatidylinositol 3-kinase activity mediates the HCMV-induced atypical M1/M2 polarization of monocytes
Q50058499Nanoliposome C6-Ceramide Increases the Anti-tumor Immune Response and Slows Growth of Liver Tumors in Mice.
Q30541000Nanoparticle clearance is governed by Th1/Th2 immunity and strain background
Q39044765Nanosized UCMSC-derived extracellular vesicles but not conditioned medium exclusively inhibit the inflammatory response of stimulated T cells: implications for nanomedicine
Q90114013Nanotopographical Coatings Induce an Early Phenotype-Specific Response of Primary Material-Resident M1 and M2 Macrophages
Q38076049Negative regulation of human mononuclear phagocyte function
Q34557551Neuropeptide FF increases M2 activation and self-renewal of adipose tissue macrophages.
Q50123084Neutrophil derived CSF1 induces macrophage polarization and promotes transplantation tolerance.
Q91795692Neutrophils contribute to spontaneous resolution of liver inflammation and fibrosis via microRNA-223
Q34513159New concepts on the immune modulation mediated by mesenchymal stem cells
Q40866271New insights into the multidimensional concept of macrophage ontogeny, activation and function.
Q36742943New tools for studying microglia in the mouse and human CNS.
Q36689930New vistas on macrophage differentiation and activation
Q42237368Next-generation sequencing of microRNAs uncovers expression signatures in polarized macrophages
Q44810398Nippostrongylus brasiliensis infection leads to the development of emphysema associated with the induction of alternatively activated macrophages
Q55262573Nitric Oxide Generated by Tumor-Associated Macrophages Is Responsible for Cancer Resistance to Cisplatin and Correlated With Syntaxin 4 and Acid Sphingomyelinase Inhibition.
Q89531887Nitric oxide orchestrates metabolic rewiring in M1 macrophages by targeting aconitase 2 and pyruvate dehydrogenase
Q39645906Nod2-induced autocrine interleukin-1 alters signaling by ERK and p38 to differentially regulate secretion of inflammatory cytokines
Q55456543Non-inflammatory tumor microenvironment of diffuse intrinsic pontine glioma.
Q41828582Noncanonical Notch signaling modulates cytokine responses of dendritic cells to inflammatory stimuli.
Q35877268Novel Markers to Delineate Murine M1 and M2 Macrophages
Q42703602Novel fat depot-specific mechanisms underlie resistance to visceral obesity and inflammation in 11 β-hydroxysteroid dehydrogenase type 1-deficient mice
Q38032155Novel immune signals and atherosclerosis
Q47248842Novel insights in the metabolic syndrome-induced oxidative stress and inflammation-mediated atherosclerosis
Q60042076Novel macrophage polarization model: from gene expression to identification of new anti-inflammatory molecules
Q37195126Novel pathways in the pathobiology of human abdominal aortic aneurysms
Q37612556Obesity activates a program of lysosomal-dependent lipid metabolism in adipose tissue macrophages independently of classic activation
Q33777394Obesity related methylation changes in DNA of peripheral blood leukocytes
Q39011826One microenvironment does not fit all: heterogeneity beyond cancer cells
Q51653431Onionin A, a sulfur-containing compound isolated from onions, impairs tumor development and lung metastasis by inhibiting the protumoral and immunosuppressive functions of myeloid cells.
Q54607427Optimization of prednisolone-loaded long-circulating liposomes via application of Quality by Design (QbD) approach.
Q37945434Optimizing dynamic interactions between a cardiac patch and inflammatory host cells
Q33910956Orientia tsutsugamushi stimulates an original gene expression program in monocytes: relationship with gene expression in patients with scrub typhus
Q41910192Origin and Functions of Tumor-Associated Myeloid Cells (TAMCs).
Q90522903Overexpression of Murine Rnaset2 in a Colon Syngeneic Mouse Carcinoma Model Leads to Rebalance of Intra-Tumor M1/M2 Macrophage Ratio, Activation of T Cells, Delayed Tumor Growth, and Rejection
Q43226769PPAR activation induces M1 macrophage polarization via cPLA₂-COX-2 inhibition, activating ROS production against Leishmania mexicana.
Q38020769Particulate systems for targeting of macrophages: basic and therapeutic concepts.
Q92802012Pathogen Evasion of Chemokine Response Through Suppression of CXCL10
Q37748077Pathogenic mechanisms of allergic inflammation: atopic asthma as a paradigm
Q35213832Pathologic correlates of primary central nervous system lymphoma defined in an orthotopic xenograft model
Q37368874Percutaneous Transluminal Angioplasty in Patients with Peripheral Arterial Disease Does Not Affect Circulating Monocyte Subpopulations.
Q33346650Performance comparison of two microarray platforms to assess differential gene expression in human monocyte and macrophage cells
Q42091220Periostin in the Cancer Stroma of Mycosis Fungoides Palmaris et Plantaris: A Case Report and Immunohistochemical Study
Q90570366Peripheral Blood Monocytes With an Antiinflammatory Phenotype Display Limited Phagocytosis and Oxidative Burst in Patients With Visceral Leishmaniasis
Q35109379Peripheral blood gene expression profiles in metabolic syndrome, coronary artery disease and type 2 diabetes
Q39973799Peroxisome proliferator-activated receptor gamma activation promotes infiltration of alternatively activated macrophages into adipose tissue.
Q90211749Pharmacologic Considerations in the Disposition of Antibodies and Antibody-Drug Conjugates in Preclinical Models and in Patients
Q38761977Pharmacologic immunosuppression of mononuclear phagocyte phagocytosis by caffeine
Q38622042Pharmacologic or Genetic Targeting of Glutamine Synthetase Skews Macrophages toward an M1-like Phenotype and Inhibits Tumor Metastasis.
Q91706849Pharmacological Targeting of Microglial Activation: New Therapeutic Approach
Q37998021Phenotypic and functional heterogeneity of macrophages and dendritic cell subsets in the healthy and atherosclerosis-prone aorta
Q50576197Phenotypic and functional switch of macrophages induced by regulatory CD4+CD25+ T cells in mice.
Q27006058Phenotypic diversity and emerging new tools to study macrophage activation in bacterial infectious diseases
Q53546016Phenotypic, functional, and plasticity features of classical and alternatively activated human macrophages.
Q28585559Phosphorylation of CSF-1R Y721 mediates its association with PI3K to regulate macrophage motility and enhancement of tumor cell invasion
Q37137667Pivotal Advance: Th-1 cytokines inhibit, and Th-2 cytokines promote fibrocyte differentiation.
Q35926299Plaque Size Is Decreased but M1 Macrophage Polarization and Rupture Related Metalloproteinase Expression Are Maintained after Deleting T-Bet in ApoE Null Mice
Q40915404Plasma cells in primary melanoma. Prognostic significance and possible role of IgA.
Q34255058Polarization dictates iron handling by inflammatory and alternatively activated macrophages
Q60046849Polarization of Human Macrophages by Interleukin-4 Does Not Require ATP-Citrate Lyase
Q34525608Polysaccharide from Lentinus edodes inhibits the immunosuppressive function of myeloid-derived suppressor cells
Q38444555Porous implants modulate healing and induce shifts in local macrophage polarization in the foreign body reaction.
Q36136378Porphyromonas gingivalis-mediated signaling through TLR4 mediates persistent HIV infection of primary macrophages
Q35840586Potency analysis of cellular therapies: the emerging role of molecular assays
Q43049429Pre-operative intracellular glutathione levels of peripheral monocytes as a biomarker to predict survival of colorectal cancer patients
Q36728741Preclinical mouse models and methods for the discovery of the causes and treatments of atherosclerosis
Q36391157Preventive immunization of aged and juvenile non-human primates to β-amyloid
Q33743876Primary human macrophages serve as vehicles for vaccinia virus replication and dissemination
Q36541196Prognostic value of innate and adaptive immunity in colorectal cancer
Q64079995Programmed cell death ligand 1 (PD-L1) blockade attenuates metastatic colon cancer growth in cAMP-response element-binding protein (CREB)-binding protein (CBP)/β-catenin inhibitor-treated livers
Q90602239Prometastatic Molecular Profiles in Breast Tumors From Socially Isolated Women
Q41340042Promising landscape for regulating macrophage polarization: epigenetic viewpoint
Q33832775Promotion of Tumor Invasion by Tumor-Associated Macrophages: The Role of CSF-1-Activated Phosphatidylinositol 3 Kinase and Src Family Kinase Motility Signaling
Q38854845Protein Thiol Redox Signaling in Monocytes and Macrophages
Q47719302Proteoglycans as Immunomodulators of the Innate Immune Response to Lung Infection
Q36134002Proteomic Analysis Reveals Distinct Metabolic Differences Between Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) and Macrophage Colony Stimulating Factor (M-CSF) Grown Macrophages Derived from Murine Bone Marrow Cells
Q47831410Proteomic Signature Reveals Modulation of Human Macrophage Polarization and Functions Under Differing Environmental Oxygen Conditions.
Q35375667Proteomic biosignatures for monocyte-macrophage differentiation.
Q35136446Proteomic characterization of human proinflammatory M1 and anti-inflammatory M2 macrophages and their response to Candida albicans.
Q35025824Pulsed stable isotope labeling of amino acids in cell culture uncovers the dynamic interactions between HIV-1 and the monocyte-derived macrophage
Q46667650Purinergic signaling during macrophage differentiation results in M2 alternative activated macrophages
Q27328830Quaking promotes monocyte differentiation into pro-atherogenic macrophages by controlling pre-mRNA splicing and gene expression
Q40734962Quantitation of Productively Infected Monocytes and Macrophages of Simian Immunodeficiency Virus-Infected Macaques
Q33671251Quantitative profiling of glycerophospholipids during mouse and human macrophage differentiation using targeted mass spectrometry
Q34607733RNA sequencing and transcriptomal analysis of human monocyte to macrophage differentiation
Q37284227RON receptor tyrosine kinase, a negative regulator of inflammation, is decreased during simian immunodeficiency virus-associated central nervous system disease
Q30836198Rab17 mediates differential antigen sorting following efferocytosis and phagocytosis
Q35158209Rac2 controls tumor growth, metastasis and M1-M2 macrophage differentiation in vivo
Q45057583Rapamycin unbalances the polarization of human macrophages to M1.
Q35871716Rapid Alterations in Perirenal Adipose Tissue Transcriptomic Networks with Cessation of Voluntary Running
Q50045161Rapid activation of tumor-associated macrophages boosts preexisting tumor immunity.
Q53475860Receptor Activator of NF-κB Ligand Promotes the Production of CCL17 from RANK+ M2 Macrophages.
Q28389274Reciprocal modulation between microglia and astrocyte in reactive gliosis following the CNS injury
Q47223452Recruitment and therapeutic application of macrophages in skeletal muscles after hind limb ischemia
Q35961926Redefining the transcriptional regulatory dynamics of classically and alternatively activated macrophages by deepCAGE transcriptomics.
Q88298734Reduced substrate stiffness promotes M2-like macrophage activation and enhances peroxisome proliferator-activated receptor γ expression
Q33917521Regional expression of HOXA4 along the aorta and its potential role in human abdominal aortic aneurysms
Q37629850Regulation of Epigenetic Modifiers, Including KDM6B, by Interferon-γ and Interleukin-4 in Human Macrophages.
Q41313325Regulation of Human Macrophage M1-M2 Polarization Balance by Hypoxia and the Triggering Receptor Expressed on Myeloid Cells-1.
Q90479612Regulation of Macrophage and Dendritic Cell Function by Chondroitin Sulfate in Innate to Antigen-Specific Adaptive Immunity
Q34317391Regulation of activation-associated microRNA accumulation rates during monocyte-to-macrophage differentiation
Q37989491Regulation of gene expression in atherosclerosis: insights from microarray studies in monocytes/macrophages
Q36232198Regulation of inflammation by interleukin-4: a review of "alternatives"
Q33691344Regulation of inflammatory gene expression in PBMCs by immunostimulatory botanicals
Q90320984Regulation of monoamine oxidase A (MAO-A) expression, activity, and function in IL-13-stimulated monocytes and A549 lung carcinoma cells
Q33852590Regulation of pattern recognition receptors by the apolipoprotein A-I mimetic peptide 4F.
Q89777635Regulation of the maturation of human monocytes into immunosuppressive macrophages
Q54587789Regulators of macrophage activation.
Q36340875Regulatory monocytes in helminth infections: insights from the modulation during human hookworm infection
Q34175955Relationship of MMP-14 and TIMP-3 expression with macrophage activation and human atherosclerotic plaque vulnerability
Q37542824Renal vein cytokine release as an index of renal parenchymal inflammation in chronic experimental renal artery stenosis
Q37889633Repertoire of microglial and macrophage responses after spinal cord injury
Q27322789Replication of Salmonella enterica Serovar Typhimurium in Human Monocyte-Derived Macrophages
Q88312733Repolarizing heterogeneous leukemia-associated macrophages with more M1 characteristics eliminates their pro-leukemic effects
Q33897597Reprint of: A rapid increase in macrophage-derived versican and hyaluronan in infectious lung disease.
Q26852569Resolution of inflammation: an integrated view
Q36473183Response gene to complement 32 (RGC-32) expression on M2-polarized and tumor-associated macrophages is M-CSF-dependent and enhanced by tumor-derived IL-4.
Q33707131Retracted: Macrophage Colony-Stimulating Factor Augments Tie2-Expressing Monocyte Differentiation, Angiogenic Function, and Recruitment in a Mouse Model of Breast Cancer
Q37657853Rheb1 deletion in myeloid cells aggravates OVA-induced allergic inflammation in mice
Q34997115Role of CLIC4 in the host innate responses to bacterial lipopolysaccharide
Q55716397Role of Human Macrophage Polarization in Inflammation during Infectious Diseases.
Q52628012Role of Macrophages in Brain Tumor Growth and Progression.
Q64937621Role of Macrophages in Cardioprotection.
Q64955233Role of Myeloid-Epithelial-Reproductive Tyrosine Kinase and Macrophage Polarization in the Progression of Atherosclerotic Lesions Associated With Nonalcoholic Fatty Liver Disease.
Q49365787Role of SLC7A5 in Metabolic Reprogramming of Human Monocyte/Macrophage Immune Responses.
Q58862468Role of Tumor-Associated Macrophages (TAM) in Cancer Related Inflammation
Q37016784Role of complement cascade in abdominal aortic aneurysms
Q46353347Role of inflammation in right ventricular damage and repair following experimental pulmonary embolism in rats
Q34335507Role of macrophages in the pathogenesis of atopic dermatitis
Q37960792Role of tumor-associated macrophages in the progression of hepatocellular carcinoma
Q40207052Roles of M1 and M2 Macrophages in Herpes Simplex Virus 1 Infectivity
Q38396105Roles of microglia in brain development, tissue maintenance and repair.
Q89820701S100A12 Expression Is Modulated During Monocyte Differentiation and Reflects Periodontitis Severity
Q33576194SAA drives proinflammatory heterotypic macrophage differentiation in the lung via CSF-1R-dependent signaling
Q33702432SCRG1 suppresses LPS-induced CCL22 production through ERK1/2 activation in mouse macrophage Raw264.7 cells
Q91678658SIRT1/2 orchestrate acquisition of DNA methylation and loss of histone H3 activating marks to prevent premature activation of inflammatory genes in macrophages
Q54209057SIV Latency in Macrophages in the CNS.
Q58551333STAT2 Signaling Regulates Macrophage Phenotype During Influenza and Bacterial Super-Infection
Q34776805STAT6⁻/⁻ mice exhibit decreased cells with alternatively activated macrophage phenotypes and enhanced disease severity in murine neurocysticercosis
Q89174615Salmonella Typhimurium Infection of Human Monocyte-Derived Macrophages
Q33759932Selection of reliable reference genes during THP-1 monocyte differentiation into macrophages.
Q38840798Selective phosphorylation during early macrophage differentiation
Q36210558Self-limited versus delayed resolution of acute inflammation: temporal regulation of pro-resolving mediators and microRNA
Q37710693Self-renewal and phenotypic conversion are the main physiological responses of macrophages to the endogenous estrogen surge.
Q38231265Serotonin modulation of macrophage polarization: inflammation and beyond
Q42234796Serum exosomes and cytokines promote a T-helper cell type 2 environment in the peripheral blood of glioblastoma patients
Q82680101Serum levels of soluble CD163 in patients with systemic sclerosis
Q47148937Short-term sustained hyperglycaemia fosters an archetypal senescence-associated secretory phenotype in endothelial cells and macrophages.
Q51370563Sialylation and desialylation dynamics of monocytes upon differentiation and polarization to macrophages.
Q38204175Signaling pathways involved in MDSC regulation
Q39693531Significance of alternatively activated macrophages in patients with intrahepatic cholangiocarcinoma.
Q35083493Silencing collapsin response mediator protein-2 reprograms macrophage phenotype and improves infarct healing in experimental myocardial infarction model
Q54233279Similarities and differences between helminth parasites and cancer cell lines in shaping human monocytes: Insights into parallel mechanisms of immune evasion.
Q33633305Similarity and diversity in macrophage activation by nematodes, trematodes, and cestodes.
Q89721950Single-Cell Genomic Characterization Reveals the Cellular Reprogramming of the Gastric Tumor Microenvironment
Q33654352Single-cell RNA-seq enables comprehensive tumour and immune cell profiling in primary breast cancer
Q41078728Site-Specific Immunomodulator: A Novel Treatment for Crohn's Disease
Q37363412Small ruminant macrophage polarization may play a pivotal role on lentiviral infection.
Q33865189Smoking-dependent reprogramming of alveolar macrophage polarization: implication for pathogenesis of chronic obstructive pulmonary disease
Q55286227Soluble CD163 as a Potential Biomarker in Systemic Sclerosis.
Q88708898Soya protein β-conglycinin ameliorates fatty liver and obesity in diet-induced obese mice through the down-regulation of PPARγ
Q36278447Species dependent impact of helminth-derived antigens on human macrophages infected with Mycobacterium tuberculosis: Direct effect on the innate anti-mycobacterial response.
Q91142553Sterile particle-induced inflammation is mediated by macrophages releasing IL-33 through a Bruton's tyrosine kinase-dependent pathway
Q33634686Stimulation of angiogenesis resulting from cooperation between macrophages and MDA-MB-231 breast cancer cells: proposed molecular mechanism and effect of tetrathiomolybdate
Q39519422Stimulation of neoplastic mouse lung cell proliferation by alveolar macrophage-derived, insulin-like growth factor-1 can be blocked by inhibiting MEK and PI3K activation
Q38604926Studies on Colony Stimulating Factor Receptor-1 and Ligands Colony Stimulating Factor-1 and Interleukin-34 in Alzheimer's Disease Brains and Human Microglia
Q45357964Study of macrophages in BCG granulomas in different compartments of the mononuclear phagocyte system
Q28397011Suppression of antigen-specific CD4+ T cell activation by SRA/CD204 through reducing the immunostimulatory capability of antigen-presenting cell
Q39799161Suppressive effect on MDC and IP-10 expression in monocytes by endocrine disruptor chemicals
Q34183899Surfing the data tsunami, a bioinformatic dissection of the proangiogenic monocyte
Q36241272Sustained generation of nitric oxide and control of mycobacterial infection requires argininosuccinate synthase 1.
Q94671452Synovial tissue transcriptomes of long-standing rheumatoid arthritis are dominated by activated macrophages that reflect microbial stimulation
Q34544517Synthetic cationic peptide IDR-1018 modulates human macrophage differentiation
Q55692468Systematic RNA-interference in primary human monocyte-derived macrophages: A high-throughput platform to study foam cell formation.
Q33730296Systemic administration of TLR3 agonist induces IL-7 expression and IL-7-dependent CXCR3 ligand production in the lung
Q37636630TAM receptors Tyro3 and Mer as novel targets in colorectal cancer.
Q37588446TGF-β induces M2-like macrophage polarization via SNAIL-mediated suppression of a pro-inflammatory phenotype
Q34276027TGFβ in T cell biology and tumor immunity: Angel or devil?
Q26744557TIM-3 Regulates Distinct Functions in Macrophages
Q43608830TLR activation of tumor-associated macrophages from ovarian cancer patients triggers cytolytic activity of NK cells
Q35774778TNF-related apoptosis-inducing ligand promotes human preadipocyte proliferation via ERK1/2 activation
Q89602437TNF-α and INF-γ primed canine stem cell-derived extracellular vesicles alleviate experimental murine colitis
Q24607229TRIM family proteins and their emerging roles in innate immunity
Q34262107TRIM13 is a negative regulator of MDA5-mediated type I interferon production
Q39014212TRIM8 regulates stemness in glioblastoma through PIAS3-STAT3.
Q33899221TSG-6 Secreted by Human Adipose Tissue-derived Mesenchymal Stem Cells Ameliorates DSS-induced colitis by Inducing M2 Macrophage Polarization in Mice.
Q64936338Taenia crassiceps-Excreted/Secreted Products Induce a Defined MicroRNA Profile that Modulates Inflammatory Properties of Macrophages.
Q38657999Targeting GM-CSF in inflammatory diseases
Q55315292Targeting Macrophages in Cancer: From Bench to Bedside.
Q58801754Targeting T Cell Metabolism for Improvement of Cancer Immunotherapy
Q37785098Targeting the microenvironment
Q37997073Tec family kinases in inflammation and disease
Q36377797Temporal phenotypic features distinguish polarized macrophages in vitro
Q55265444The Bicarbonate Transporter SLC4A7 Plays a Key Role in Macrophage Phagosome Acidification.
Q51251704The CD44-Mediated Uptake of Hyaluronic Acid-Based Carriers in Macrophages.
Q37728051The CXCL12/CXCR4 axis is involved in the maintenance of Th2 bias at the maternal/fetal interface in early human pregnancy
Q40049468The IL-2/CD25 pathway determines susceptibility to T1D in humans and NOD mice
Q57062755The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection
Q29615845The M1 and M2 paradigm of macrophage activation: time for reassessment
Q35879521The Macrophage Inhibitor CNI-1493 Blocks Metastasis in a Mouse Model of Ewing Sarcoma through Inhibition of Extravasation
Q50199038The Macrophage Mannose Receptor Regulate Mannan-Induced Psoriasis, Psoriatic Arthritis, and Rheumatoid Arthritis-Like Disease Models.
Q26771455The Macrophage Switch in Obesity Development
Q34092270The Probiotic Mixture VSL#3 Alters the Morphology and Secretion Profile of Both Polarized and Unpolarized Human Macrophages in a Polarization-Dependent Manner
Q26752888The Reactive Oxygen Species in Macrophage Polarization: Reflecting Its Dual Role in Progression and Treatment of Human Diseases
Q41369877The Rhoptry Pseudokinase ROP54 Modulates Toxoplasma gondii Virulence and Host GBP2 Loading.
Q37732574The anti-inflammatory and immunosuppressive effects of glucocorticoids, recent developments and mechanistic insights
Q54201958The assembly of lipid droplets and their roles in challenged cells.
Q24606039The chemokine CCL18 causes maturation of cultured monocytes to macrophages in the M2 spectrum
Q38097660The complexity of arterial classical monocyte recruitment.
Q38675589The contribution of tumor-associated macrophages in glioma neo-angiogenesis and implications for anti-angiogenic strategies
Q38964911The contributions of lung macrophage and monocyte heterogeneity to influenza pathogenesis
Q47549111The cytomegalovirus protein US31 induces inflammation through mono-macrophages in systemic lupus erythematosus by promoting NF-κB2 activation
Q35067772The development of nasal polyp disease involves early nasal mucosal inflammation and remodelling
Q21134765The dispanins: a novel gene family of ancient origin that contains 14 human members
Q30440948The divergence, actions, roles, and relatives of sodium-coupled bicarbonate transporters
Q38195893The dynamic lives of macrophage and dendritic cell subsets in atherosclerosis
Q36602372The effect of source animal age upon the in vivo remodeling characteristics of an extracellular matrix scaffold.
Q51272248The effects of exogenous fatty acids and niacin on human monocyte-macrophage plasticity.
Q37400831The effects on weight loss and gene expression in adipose and hepatic tissues of very-low carbohydrate and low-fat isoenergetic diets in diet-induced obese mice
Q38511091The generation and properties of human macrophage populations from hemopoietic stem cells.
Q51730629The histamine H4 receptor modulates the differentiation process of human monocyte-derived M1 macrophages and the release of CCL4/MIP-1β from fully differentiated M1 macrophages.
Q39364591The homeobox transcription factor VentX controls human macrophage terminal differentiation and proinflammatory activation
Q38199452The host response to allogeneic and xenogeneic biological scaffold materials
Q54337107The human C-type lectin-like receptor CLEC-1 is upregulated by TGF-β and primarily localized in the endoplasmic membrane compartment.
Q33826894The human cytomegalovirus UL36 gene controls caspase-dependent and -independent cell death programs activated by infection of monocytes differentiating to macrophages
Q34164767The human tissue-biomaterial interface: a role for PPARγ-dependent glucocorticoid receptor activation in regulating the CD163+ M2 macrophage phenotype
Q52760295The influence of vitamin D on M1 and M2 macrophages in patients with Crohn's disease.
Q39068713The innate immune factor apolipoprotein L1 restricts HIV-1 infection
Q96816703The interaction between ferroptosis and lipid metabolism in cancer
Q34411026The interaction of human natural killer cells with either unpolarized or polarized macrophages results in different functional outcomes
Q28086874The ischemic environment drives microglia and macrophage function
Q38823963The kidney regulates regeneration, but don't upset the balance
Q37852901The lens as a model for fibrotic disease
Q36351200The limited role of interferon-γ in systemic juvenile idiopathic arthritis cannot be explained by cellular hyporesponsiveness
Q38971630The mRNA expression of immune-related genes in crossbred and Tharparkar cattle in response to in vitro infection with Theileria annulata.
Q38605333The macrophage and its role in inflammation and tissue repair: mathematical and systems biology approaches
Q42368975The macrophage marker translocator protein (TSPO) is down-regulated on pro-inflammatory 'M1' human macrophages
Q35931854The macrophage phagocytic receptor CD36 promotes fibrogenic pathways on removal of apoptotic cells during chronic kidney injury
Q91530377The macrophage tetraspan MS4A4A enhances dectin-1-dependent NK cell-mediated resistance to metastasis
Q21090526The mannose receptor mediates dengue virus infection of macrophages
Q64964429The metabolic syndrome modifies the mRNA expression profile of extracellular vesicles derived from porcine mesenchymal stem cells.
Q37828326The mononuclear phagocyte system of the pig as a model for understanding human innate immunity and disease
Q37282249The multifaceted contributions of leukocyte subsets to atherosclerosis: lessons from mouse models
Q37741022The multiple roles of monocyte subsets in steady state and inflammation
Q34232750The omega-3 fatty acid docosahexaenoic acid favorably modulates the inflammatory pathways and macrophage polarization within aorta of LDLR(-/-) mice.
Q37297484The protozoan parasite Theileria annulata alters the differentiation state of the infected macrophage and suppresses musculoaponeurotic fibrosarcoma oncogene (MAF) transcription factors.
Q26829387The regulation of inflammation by interferons and their STATs
Q38593722The role of inflammatory biomarkers in developing targeted cardiovascular therapies: lessons from the cardiovascular inflammation reduction trials
Q38975948The role of macrophage phenotype in vascularization of tissue engineering scaffolds
Q36913752The role of peritoneal alternatively activated macrophages in the process of peritoneal fibrosis related to peritoneal dialysis
Q37150404The role of type 1 interferon in systemic sclerosis
Q33523382The transcriptome of human monocyte subsets begins to emerge.
Q96348548The tumor immune microenvironmental analysis of 2,033 transcriptomes across 7 cancer types
Q34343645The tumor microenvironment in colorectal carcinogenesis
Q96126882The tumour microenvironment shapes dendritic cell plasticity in a human organotypic melanoma culture
Q28553086Therapeutic Benefits of Induced Pluripotent Stem Cells in Monocrotaline-Induced Pulmonary Arterial Hypertension
Q48261561Therapeutic effects of CSF1R-blocking antibodies in multiple myeloma
Q41849692Tie2 signaling cooperates with TNF to promote the pro-inflammatory activation of human macrophages independently of macrophage functional phenotype
Q37508288Time Series miRNA-mRNA integrated analysis reveals critical miRNAs and targets in macrophage polarization
Q35315722Time and Demand are Two Critical Dimensions of Immunometabolism: The Process of Macrophage Activation and the Pentose Phosphate Pathway
Q37833522Tissue engineering on matrix: future of autologous tissue replacement
Q36540595Tissue factor expression by myeloid cells contributes to protective immune response against Mycobacterium tuberculosis infection
Q37329573Tolerance and M2 (alternative) macrophage polarization are related processes orchestrated by p50 nuclear factor kappaB.
Q38453096Tolerogenic dendritic cells show gene expression profiles that are different from those of immunogenic dendritic cells in DBA/1 mice.
Q38686877Toll-like receptors participate in macrophage activation and intracellular control of Leishmania (Viannia) panamensis
Q35090382Toxoplasma polymorphic effectors determine macrophage polarization and intestinal inflammation.
Q34582826Transcript origin analysis identifies antigen-presenting cells as primary targets of socially regulated gene expression in leukocytes
Q35723687Transcriptional (ChIP-Chip) Analysis of ELF1, ETS2, RUNX1 and STAT5 in Human Abdominal Aortic Aneurysm
Q33728411Transcriptional diversity during monocyte to macrophage differentiation
Q60305742Transcriptional profiling identifies novel regulators of macrophage polarization
Q34994488Transcriptional profiling of human monocytes identifies the inhibitory receptor CD300a as regulator of transendothelial migration
Q35902160Transcriptional profiling of macrophages derived from monocytes and iPS cells identifies a conserved response to LPS and novel alternative transcription
Q42215028Transcriptional profiling predicts overwhelming homology of Schwann cells, olfactory ensheathing cells, and Schwann cell-like glia
Q37949245Transcriptional regulation of macrophage polarization: enabling diversity with identity
Q37040044Transcriptome analysis reveals human cytomegalovirus reprograms monocyte differentiation toward an M1 macrophage
Q91896948Transcriptome profile of rat genes in bone marrow-derived macrophages at different activation statuses by RNA-sequencing
Q98303052Transcriptome sequencing supports a conservation of macrophage polarization in fish
Q34659689Transcriptome-based network analysis reveals a spectrum model of human macrophage activation.
Q35584125Transcriptomic analysis of human polarized macrophages: more than one role of alternative activation?
Q38782911Transcriptomic analysis of monocytes and macrophages derived from CLL patients which display differing abilities to respond to therapeutic antibody immune complexes.
Q38204490Transcriptomic network support distinct roles of classical and non-classical monocytes in human.
Q37548762Transcriptomic profiling of the development of the inflammatory response in human monocytes in vitro.
Q98611601Transcriptomics uncovers substantial variability associated with alterations in manufacturing processes of macrophage cell therapy products
Q64061191Traumatic Spinal Cord Injury: An Overview of Pathophysiology, Models and Acute Injury Mechanisms
Q58883590Treatment with a Urokinase Receptor-derived Cyclized Peptide Improves Experimental Colitis by Preventing Monocyte Recruitment and Macrophage Polarization
Q34059582Triggering TLR2, -3, -4, -5, and -8 reinforces the restrictive nature of M1- and M2-polarized macrophages to HIV.
Q36829147Trophic macrophages in development and disease
Q34503570Trophoblast induces monocyte differentiation into CD14+/CD16+ macrophages
Q39155704Tumor associated macrophage expressing CD204 is associated with tumor aggressiveness of esophageal squamous cell carcinoma.
Q34306107Tumor associated macrophages and neutrophils in tumor progression
Q33882555Tumor progression stage and anatomical site regulate tumor-associated macrophage and bone marrow-derived monocyte polarization
Q39931086Tumor-associated macrophage-induced invasion and angiogenesis of human basal cell carcinoma cells by cyclooxygenase-2 induction.
Q37594369Tumor-associated macrophages (TAM) as major players of the cancer-related inflammation
Q58699122Tumor-associated macrophages derived CCL18 promotes metastasis in squamous cell carcinoma of the head and neck
Q35906771Tumor-associated macrophages in the cutaneous SCC microenvironment are heterogeneously activated
Q91835845Tumor-associated macrophages in tumor metastasis: biological roles and clinical therapeutic applications
Q36849038Tumor-associated macrophages subvert T-cell function and correlate with reduced survival in clear cell renal cell carcinoma
Q38105286Tumor-associated macrophages: functional diversity, clinical significance, and open questions
Q92666788Tumor-associated reactive astrocytes aid the evolution of immunosuppressive environment in glioblastoma
Q39041039Tumor-associated vacuolar ATPase subunit promotes tumorigenic characteristics in macrophages
Q35872012Tumor-cell co-culture induced alternative activation of macrophages is modulated by interferons in vitro
Q104073775Tumor-promoting macrophages prevail in malignant ascites of advanced gastric cancer
Q47285918Tuning inflammation and immunity by the negative regulators IL-1R2 and IL-1R8.
Q37015896Two unique human decidual macrophage populations.
Q53497217Type I interferon-dependent and -independent expression of tripartite motif proteins in immune cells.
Q90427714USP17 mediates macrophage-promoted inflammation and stemness in lung cancer cells by regulating TRAF2/TRAF3 complex formation
Q39317949Ubiquitin enzymes in the regulation of immune responses
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