Exploiting genomic knowledge in optimising molecular breeding programmes: algorithms from evolutionary computing

scientific article (publication date: 2012)

Exploiting genomic knowledge in optimising molecular breeding programmes: algorithms from evolutionary computing is …
instance of (P31):
scholarly articleQ13442814

External links are
P819ADS bibcode2012PLoSO...748862O
P356DOI10.1371/JOURNAL.PONE.0048862
P3181OpenCitations bibliographic resource ID2086926
P932PMC publication ID3504065
P698PubMed publication ID23185279
P5875ResearchGate publication ID233775451

P50authorDouglas KellQ5301676
Steve O'HaganQ43371027
P2093author name stringJoshua Knowles
P2860cites workGenetics. A century of corn selectionQ81362902
Mechanisms of drug combinations: interaction and network perspectivesQ83265745
Besting Johnny AppleseedQ84068723
Strategy for applying genome-wide selection in dairy cattleQ59664738
Impact of epistasis and pleiotropy on evolutionary adaptationQ59867557
A consensus yeast metabolic network reconstruction obtained from a community approach to systems biologyQ21147058
Finding the missing heritability of complex diseasesQ22122198
A protocol for generating a high-quality genome-scale metabolic reconstructionQ24603373
The rate and molecular spectrum of spontaneous mutations in Arabidopsis thalianaQ24622979
Exploring protein fitness landscapes by directed evolutionQ24630945
Synthetic biology: new engineering rules for an emerging disciplineQ24672399
Evolutionary programming as a platform for in silico metabolic engineeringQ25257616
Large-scale sequestration of atmospheric carbon via plant roots in natural and agricultural ecosystems: why and howQ26850157
An epistatic ratchet constrains the direction of glucocorticoid receptor evolutionQ27657553
Sequencing technologies - the next generationQ27860568
Statistical strategies for avoiding false discoveries in metabolomics and related experimentsQ27887473
The automation of science.Q27937312
High-resolution mapping of meiotic crossovers and non-crossovers in yeastQ27938210
The genetic landscape of a cellQ28131628
The evolutionary origin of complex featuresQ28203090
Surveying a local fitness landscape of a protein with epistatic sites for the study of directed evolutionQ28215989
Functional genomic hypothesis generation and experimentation by a robot scientistQ28238856
A systematic strategy for the discovery of candidate genes responsible for phenotypic variationQ28259015
Food security: the challenge of feeding 9 billion peopleQ28271670
Can we rationally design promiscuous drugs?Q28294268
Network pharmacology: the next paradigm in drug discoveryQ28297997
Breeding crop plants with deep roots: their role in sustainable carbon, nutrient and water sequestrationQ28741243
The future of the global food systemQ28749417
Common SNPs explain a large proportion of the heritability for human heightQ29547221
Next-generation DNA sequencingQ29547447
Personal genomes: The case of the missing heritabilityQ29614582
The history of cancer epigeneticsQ29617273
Prediction of total genetic value using genome-wide dense marker mapsQ29619613
Food security: contributions from science to a new and greener revolutionQ30397014
Directed molecular evolution by machine learning and the influence of nonlinear interactionsQ31152500
Optimizing the search algorithm for protein engineering by directed evolutionQ31156587
Experimental rugged fitness landscape in protein sequence spaceQ33267358
Combination chemical geneticsQ33378070
In silico modelling of directed evolution: Implications for experimental design and stepwise evolution.Q51860397
The crowding approach to niching in genetic algorithms.Q51868605
The top 100 questions of importance to the future of global agricultureQ56417900
The Robot Scientist AdamQ56784096
The effect of high-frequency random mutagenesis on in vitro protein evolution: a study on TEM-1 beta-lactamaseQ56902347
Metabolic control theory: its role in microbiology and biotechnologyQ57393977
From zero to hero—Design-based systems metabolic engineering of Corynebacterium glutamicum for l-lysine productionQ57988563
Computational science: ...ErrorQ59088849
Application of systems biology for bioprocess developmentQ37201074
Engineering microbes with synthetic biology frameworksQ37314540
Increasing crop productivity to meet global needs for feed, food, and fuelQ37363597
The accuracy of Genomic Selection in Norwegian red cattle assessed by cross-validationQ37424969
Analysis of a complete DNA-protein affinity landscapeQ38352043
Array-based evolution of DNA aptamers allows modelling of an explicit sequence-fitness landscapeQ38358691
Do proteins learn to evolve? The Hopfield network as a basis for the understanding of protein evolutionQ39263258
Combinatorial efficacy achieved through two-point blockade within a signaling pathway-a chemical genetic approach.Q40604105
Accurate prediction of genetic values for complex traits by whole-genome resequencingQ40896126
Chemical combination effects predict connectivity in biological systemsQ41851112
Scientific discovery as a combinatorial optimisation problem: how best to navigate the landscape of possible experiments?Q42135811
Selection at Linked Sites Shapes Heritable Phenotypic Variation in C. elegansQ42257621
High-order combination effects and biological robustnessQ42554339
The NK model of rugged fitness landscapes and its application to maturation of the immune responseQ42643980
Breaking proteins with mutations: threads and thresholds in evolutionQ42709838
Metabolic engineering of Escherichia coli for direct production of 1,4-butanediolQ42733691
Predictive models for population performance on real biological fitness landscapesQ43656975
Theodor Bücher Lecture. Metabolomics, modelling and machine learning in systems biology - towards an understanding of the languages of cells. Delivered on 3 July 2005 at the 30th FEBS Congress and the 9th IUBMB conference in Budapest.Q45966124
Closed-loop, multiobjective optimization of analytical instrumentation: gas chromatography/time-of-flight mass spectrometry of the metabolomes of human serum and of yeast fermentations.Q45966569
Improving catalytic function by ProSAR-driven enzyme evolutionQ46928936
Radically rethinking agriculture for the 21st centuryQ33530820
Precision genetics for complex objectives in animal agricultureQ33540638
Graph-based data selection for the construction of genomic prediction modelsQ33579835
Bioinformatics challenges for genome-wide association studiesQ33647983
Genome-wide effects of long-term divergent selectionQ33747563
Synergistic control of oscillations in the NF-kappaB signalling pathwayQ33999638
Breeding technologies to increase crop production in a changing world.Q34098317
Protein design is NP-hardQ34163003
Synthetic genomes: The next step for the synthetic genomeQ34186080
Genetic linkage and molecular evolutionQ34366168
Multicomponent therapeutics for networked systemsQ34390417
Non-linear optimization of biochemical pathways: applications to metabolic engineering and parameter estimationQ34490423
Robustness-epistasis link shapes the fitness landscape of a randomly drifting protein.Q34584004
Dissecting the genetic pathway to extreme fruit size in tomato using a cross between the small-fruited wild species Lycopersicon pimpinellifolium and L. esculentum var. Giant HeirloomQ34612467
On marker-assisted prediction of genetic value: beyond the ridgeQ34616900
Estimating polygenic effects using markers of the entire genomeQ34617102
Gene conversion: mechanisms, evolution and human diseaseQ34685613
Genomic selection.Q34724779
The second wave of synthetic biology: from modules to systemsQ34982488
Genotype-phenotype mapping: genes as computer programsQ34987779
Systematic discovery of multicomponent therapeuticsQ35147474
Meiosis: when even two is a crowd.Q35572672
Metabolic engineering of Escherichia coli for the production of L-valine based on transcriptome analysis and in silico gene knockout simulationQ35762068
Automated reverse engineering of nonlinear dynamical systemsQ35840524
Crossover interferenceQ35994291
Connecting the dots between genes, biochemistry, and disease susceptibility: systems biology modeling in human geneticsQ36020196
The efficiency of multi-target drugs: the network approach might help drug designQ36088532
Traversing the conceptual divide between biological and statistical epistasis: systems biology and a more modern synthesisQ36126271
Systems biology as a foundation for genome-scale synthetic biologyQ36578151
Synthetic biology--putting engineering into biologyQ36586096
Systems biology, metabolic modelling and metabolomics in drug discovery and developmentQ36665669
Multi-target therapeutics: when the whole is greater than the sum of the partsQ36697412
Incorporating desirable genetic characteristics from an inferior into a superior population using genomic selectionQ37102681
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectalgorithmQ8366
P304page(s)e48862
P577publication date2012-01-01
P1433published inPLOS OneQ564954
P1476titleExploiting genomic knowledge in optimising molecular breeding programmes: algorithms from evolutionary computing
P478volume7

Reverse relations

cites work (P2860)
Q30824658A novel strategy for gene selection of microarray data based on gene-to-class sensitivity information
Q42365796Evolutionary algorithms and synthetic biology for directed evolution: commentary on "on the mapping of genotype to phenotype in evolutionary algorithms" by Peter A. Whigham, Grant Dick, and James Maclaurin
Q35999546Island-Model Genomic Selection for Long-Term Genetic Improvement of Autogamous Crops
Q38287400Synthetic biology for the directed evolution of protein biocatalysts: navigating sequence space intelligently
Q28649877The Architecture of the Pollen Hoarding Syndrome in Honey Bees: Implications for Understanding Social Evolution, Behavioral Syndromes, and Selective Breeding
Q30369734The virtue of innovation: innovation through the lenses of biological evolution

Search more.