Analysis of a complete DNA-protein affinity landscape

scientific article

Analysis of a complete DNA-protein affinity landscape is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1098/RSIF.2009.0193
P932PMC publication ID2842790
P698PubMed publication ID19625306
P5875ResearchGate publication ID26688765

P50authorDouglas KellQ5301676
David C. WedgeQ39451750
Mark PlattQ57058803
P2093author name stringWilliam Rowe
Philip J Day
Joshua Knowles
P2860cites workArchitecture of ribosomal RNA: constraints on the sequence of "tetra-loops"Q24556605
Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymeraseQ27860794
In vitro selection of RNA molecules that bind specific ligandsQ27861109
Rational evolutionary design: the theory of in vitro protein evolutionQ28142227
Diversity and complexity in DNA recognition by transcription factorsQ29619632
Exploring the sequence space of a DNA aptamer using microarraysQ33304953
Prediction of hybridization and melting for double-stranded nucleic acidsQ34186238
Defining the sequence-recognition profile of DNA-binding moleculesQ34304813
Empirical fitness landscapes reveal accessible evolutionary pathsQ34606034
Generalized topological spaces in evolutionary theory and combinatorial chemistry.Q34709744
Oligonucleotide inhibitors of human thrombin that bind distinct epitopesQ36890950
Analysis of aptamer sequence activity relationshipsQ38347807
Array-based evolution of DNA aptamers allows modelling of an explicit sequence-fitness landscapeQ38358691
The NK model of rugged fitness landscapes and its application to maturation of the immune responseQ42643980
Towards a general theory of adaptive walks on rugged landscapesQ47593883
Approximate scaling properties of RNA free energy landscapes.Q52298965
From sequences to shapes and back: a case study in RNA secondary structures.Q52379672
Error Detecting and Error Correcting CodesQ55871133
P433issue44
P304page(s)397-408
P577publication date2009-07-22
P1433published inJournal of the Royal Society InterfaceQ2492390
P1476titleAnalysis of a complete DNA-protein affinity landscape
P478volume7

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cites work (P2860)
Q54474794A thousand empirical adaptive landscapes and their navigability.
Q41986173Adaptation in tunably rugged fitness landscapes: the rough Mount Fuji model
Q46070825Analysis of in vitro evolution reveals the underlying distribution of catalytic activity among random sequences.
Q36217511Beyond the Hypercube: Evolutionary Accessibility of Fitness Landscapes with Realistic Mutational Networks
Q38218962Empirical fitness landscapes and the predictability of evolution
Q34005257Evolutionary accessibility of mutational pathways
Q42365796Evolutionary algorithms and synthetic biology for directed evolution: commentary on "on the mapping of genotype to phenotype in evolutionary algorithms" by Peter A. Whigham, Grant Dick, and James Maclaurin
Q28710543Exploiting genomic knowledge in optimising molecular breeding programmes: algorithms from evolutionary computing
Q51610625Genome structure and the benefit of sex
Q92342787Genotype network intersections promote evolutionary innovation
Q42689235Hidden specificity in an apparently nonspecific RNA-binding protein
Q37184676How Good Are Statistical Models at Approximating Complex Fitness Landscapes?
Q64940140Mapping a Systematic Ribozyme Fitness Landscape Reveals a Frustrated Evolutionary Network for Self-Aminoacylating RNA.
Q26752642Methods for Improving Aptamer Binding Affinity
Q30424517Naturally selecting solutions: the use of genetic algorithms in bioinformatics
Q21145317Predictability of evolutionary trajectories in fitness landscapes
Q35079781Properties of selected mutations and genotypic landscapes under Fisher's geometric model.
Q35077513Quantifying the similarity of monotonic trajectories in rough and smooth fitness landscapes
Q55379339RNA-mediated gene regulation is less evolvable than transcriptional regulation.
Q42135811Scientific discovery as a combinatorial optimisation problem: how best to navigate the landscape of possible experiments?
Q59142935Selective Phenome Growth Adapted NK Model: A Novel Landscape to Represent Aptamer Ligand Binding
Q27316616Sort-seq under the hood: implications of design choices on large-scale characterization of sequence-function relations
Q26796990Specificity and nonspecificity in RNA-protein interactions
Q38287400Synthetic biology for the directed evolution of protein biocatalysts: navigating sequence space intelligently
Q55002438The Influence of Higher-Order Epistasis on Biological Fitness Landscape Topography.
Q52314365The architecture of an empirical genotype-phenotype map.
Q58570246The causes of evolvability and their evolution
Q54310563The robustness and evolvability of transcription factor binding sites.
Q24289511Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson’s, Huntington’s, Alzheimer’s, prions, bactericides, chemical toxicology and others as examples
Q41365190Tunably Rugged Landscapes With Known Maximum and Minimum
Q34190107Visualizing fitness landscapes

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