The Influence of Higher-Order Epistasis on Biological Fitness Landscape Topography.

scientific article published on 7 February 2018

The Influence of Higher-Order Epistasis on Biological Fitness Landscape Topography. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1007/S10955-018-1975-3
P932PMC publication ID5986866
P698PubMed publication ID29904213
P894zbMATH Open document ID1396.92054

P50authorDaniel WeinreichQ60055396
P2093author name stringRobert B Heckendorn
Yinghong Lan
Jacob Jaffe
P2860cites workEVOLUTION IN MENDELIAN POPULATIONSQ5418627
Fitness and its role in evolutionary geneticsQ22122004
Epistasis--the essential role of gene interactions in the structure and evolution of genetic systemsQ22122008
Quantitative exploration of the catalytic landscape separating divergent plant sesquiterpene synthasesQ24648100
An epistatic ratchet constrains the direction of glucocorticoid receptor evolutionQ27657553
Fitness trade-offs in the evolution of dihydrofolate reductase and drug resistance in Plasmodium falciparumQ28478215
Mechanistic approaches to the study of evolution: the functional synthesisQ28757580
Detecting High-Order Epistasis in Nonlinear Genotype-Phenotype MapsQ29002206
Darwinian evolution can follow only very few mutational paths to fitter proteinsQ29616042
Diversity and complexity in DNA recognition by transcription factorsQ29619632
Evolutionary potential of a duplicated repressor-operator pair: simulating pathways using mutation dataQ31042645
Ancestral lysozymes reconstructed, neutrality tested, and thermostability linked to hydrocarbon packing.Q45949263
Exploring the effect of sex on empirical fitness landscapesQ46501857
Fast detection of high-order epistatic interactions in genome-wide association studies using information theoretic measureQ46716313
Inferring genetic interactions from comparative fitness data.Q47102776
A NEW MEASURE OF RANK CORRELATIONQ50368941
Exact results for amplitude spectra of fitness landscapes.Q51215201
Predicting epistasis from mathematical models.Q51646640
Rapid evolutionary escape by large populations from local fitness peaks is likely in nature.Q52565464
Hidden randomness between fitness landscapes limits reverse evolution.Q54359491
Efficient linkage discovery by limited probingQ81523905
Fitness epistasis among 6 biosynthetic loci in the budding yeast Saccharomyces cerevisiaeQ83090752
Why sex and recombination?Q84878519
Analysis pipeline for the epistasis search - statistical versus biological filteringQ33574677
Enzyme Efficiency but Not Thermostability Drives Cefotaxime Resistance Evolution in TEM-1 β-LactamaseQ33590790
Fitness epistasis and constraints on adaptation in a human immunodeficiency virus type 1 protein regionQ33853183
Factors affecting the genetic load in Drosophila: synergistic epistasis and correlations among fitness componentsQ33927413
Deleterious mutations and the evolution of sexual reproductionQ34164458
Visualizing fitness landscapesQ34190107
Natural Selection and the Concept of a Protein SpaceQ34233063
On the evolutionary effect of recombinationQ34235292
Compensatory mutations restore fitness during the evolution of dihydrofolate reductaseQ34310777
Perspective: Sign epistasis and genetic constraint on evolutionary trajectoriesQ34437784
The biochemical architecture of an ancient adaptive landscapeQ34461523
The language of gene interactionQ34604883
Empirical fitness landscapes reveal accessible evolutionary pathsQ34606034
The environment affects epistatic interactions to alter the topology of an empirical fitness landscapeQ34671988
Should evolutionary geneticists worry about higher-order epistasis?Q35035921
Determination and inference of eukaryotic transcription factor sequence specificityQ35249717
Ordering gene function: the interpretation of epistasis in regulatory hierarchiesQ35281898
Quantitative Description of a Protein Fitness Landscape Based on Molecular FeaturesQ35765112
Delayed commitment to evolutionary fate in antibiotic resistance fitness landscapesQ35994748
The Context-Dependence of Mutations: A Linkage of FormalismsQ36060342
High-order epistasis shapes evolutionary trajectoriesQ36372082
Competition between recombination and epistasis can cause a transition from allele to genotype selectionQ37167732
Stepwise acquisition of pyrimethamine resistance in the malaria parasiteQ37274346
On the (un)predictability of a large intragenic fitness landscapeQ37493368
Empirical fitness landscapes and the predictability of evolutionQ38218962
Analysis of a complete DNA-protein affinity landscapeQ38352043
Detecting epistasis with the marginal epistasis test in genetic mapping studies of quantitative traitsQ38660207
Epistasis in protein evolutionQ38718935
Genotypic Context and Epistasis in Individuals and PopulationsQ38897737
Diminishing returns epistasis among beneficial mutations decelerates adaptationQ39954065
Intermolecular epistasis shaped the function and evolution of an ancient transcription factor and its DNA binding sitesQ41342939
Stochastic tunnels in evolutionary dynamicsQ42426795
The NK model of rugged fitness landscapes and its application to maturation of the immune responseQ42643980
Accessible mutational trajectories for the evolution of pyrimethamine resistance in the malaria parasite Plasmodium vivaxQ43757497
Negative epistasis between beneficial mutations in an evolving bacterial populationQ44010374
Adaptive Landscapes of Resistance Genes Change as Antibiotic Concentrations ChangeQ44381596
P433issue1
P6104maintained by WikiProjectWikiProject MathematicsQ8487137
P304page(s)208-225
P577publication date2018-02-07
P1433published inJournal of Statistical PhysicsQ1878468
P1476titleThe Influence of Higher-Order Epistasis on Biological Fitness Landscape Topography
P478volume172

Reverse relations

cites work (P2860)
Q89545822Evolutionary constraints in fitness landscapes
Q90860005Higher-order epistasis shapes the fitness landscape of a xenobiotic-degrading enzyme
Q92564353Lexical Landscapes as large in silico data for examining advanced properties of fitness landscapes
Q91891435Minimum epistasis interpolation for sequence-function relationships
Q64986364Proteostasis Environment Shapes Higher-Order Epistasis Operating on Antibiotic Resistance.

Search more.