Sterile inflammation: sensing and reacting to damage

scientific article (publication date: December 2010)

Sterile inflammation: sensing and reacting to damage is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/NRI2873
P3181OpenCitations bibliographic resource ID187490
P932PMC publication ID3114424
P698PubMed publication ID21088683
P5875ResearchGate publication ID47815802

P2093author name stringNuñez G
Chen GY
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IL-33 induces neutrophil migration in rheumatoid arthritis and is a target of anti-TNF therapyQ57231967
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Mincle is an ITAM-coupled activating receptor that senses damaged cellsQ28506757
The receptor for advanced glycation end products (RAGE) is a cellular binding site for amphoterin. Mediation of neurite outgrowth and co-expression of rage and amphoterin in the developing nervous systemQ28567291
ATP activates a reactive oxygen species-dependent oxidative stress response and secretion of proinflammatory cytokines in macrophagesQ28568956
Role of receptor for advanced glycation end-product (RAGE) and the JAK/STAT-signaling pathway in AGE-induced collagen production in NRK-49F cellsQ28570142
CD36 is a sensor of diacylglyceridesQ28591244
The receptor for advanced glycation end-products (RAGE) directly binds to ERK by a D-domain-like docking siteQ28645645
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Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expressionQ29615589
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Uric acid promotes an acute inflammatory response to sterile cell death in miceQ33882855
The matrix component biglycan is proinflammatory and signals through Toll-like receptors 4 and 2 in macrophagesQ33895703
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mRNA is an endogenous ligand for Toll-like receptor 3.Q34290592
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Hyaluronan fragments act as an endogenous danger signal by engaging TLR2.Q34544391
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RAGE is a multiligand receptor of the immunoglobulin superfamily: implications for homeostasis and chronic diseaseQ34836475
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Signalling through C-type lectin receptors: shaping immune responsesQ34986405
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Myd88-dependent positioning of Ptgs2-expressing stromal cells maintains colonic epithelial proliferation during injuryQ35250974
IL-33, the IL-1-like cytokine ligand for ST2 receptor, is a chromatin-associated nuclear factor in vivoQ35575987
Caspase-1 independent IL-1beta production is critical for host resistance to mycobacterium tuberculosis and does not require TLR signaling in vivoQ36168205
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Immunology and immunotherapy of Alzheimer's diseaseQ36460445
Hyaluronan in tissue injury and repairQ36824173
Receptor for advanced glycation end products (RAGE) deficiency attenuates the development of atherosclerosis in diabetesQ36842628
TLR3 is an endogenous sensor of tissue necrosis during acute inflammatory eventsQ36946570
Lack of Toll-like receptor 4 or myeloid differentiation factor 88 reduces atherosclerosis and alters plaque phenotype in mice deficient in apolipoprotein EQ36986664
Interleukin (IL)-1 promotes allogeneic T cell intimal infiltration and IL-17 production in a model of human artery rejection.Q37019593
Acetaminophen-induced hepatotoxicity in mice is dependent on Tlr9 and the Nalp3 inflammasome.Q37073714
Secondary necrosis in multicellular animals: an outcome of apoptosis with pathogenic implications.Q37103259
Identification of a dendritic cell receptor that couples sensing of necrosis to immunityQ37164859
Hepatocyte necrosis induced by oxidative stress and IL-1 alpha release mediate carcinogen-induced compensatory proliferation and liver tumorigenesisQ37255168
Sustained effects of interleukin-1 receptor antagonist treatment in type 2 diabetes.Q37319117
CD24 and Siglec-10 selectively repress tissue damage-induced immune responses.Q37396101
Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptorsQ37433274
Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasomeQ37453447
IL-1 pathways in inflammation and human diseasesQ37696955
IL-1: discoveries, controversies and future directionsQ37702138
Isolation and expression profiling of genes upregulated in bone marrow-derived mononuclear cells of rheumatoid arthritis patients.Q38307957
RAGE-dependent signaling in microglia contributes to neuroinflammation, Abeta accumulation, and impaired learning/memory in a mouse model of Alzheimer's diseaseQ39638245
Identification of the cellular sensor that stimulates the inflammatory response to sterile cell death.Q39729219
Identification of a key pathway required for the sterile inflammatory response triggered by dying cellsQ40119160
Pivotal advance: analysis of proinflammatory activity of highly purified eukaryotic recombinant HMGB1 (amphoterin).Q40230859
HMGB1 signals through toll-like receptor (TLR) 4 and TLR2.Q40249835
P433issue12
P407language of work or nameEnglishQ1860
P921main subjectinflammationQ101991
P304page(s)826-37
P577publication date2010-12-01
P1433published inNature Reviews ImmunologyQ43355
P1476titleSterile inflammation: sensing and reacting to damage
P478volume10

Reverse relations

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Q52603055Cerebral ischemia and neuroregeneration.
Q34473701Characteristics of circulating CD31(+) cells from patients with coronary artery disease
Q92472627Characterization of IL-17-producing T helper cells-like autoreactive T cells in aged mice
Q37220007Characterization of Inflammatory Response in Acute-on-Chronic Liver Failure and Relationship with Prognosis.
Q47856006Chemokines and mitochondrial products activate neutrophils to amplify organ injury during mouse acute liver failure
Q83169012Chemokines in health and disease
Q33761615Chikusetsu saponin IVa ameliorates high fat diet-induced inflammation in adipose tissue of mice through inhibition of NLRP3 inflammasome activation and NF-κB signaling
Q27024737Cholesterol crystals and inflammation
Q34813437Cholesterol regulation of receptor-interacting protein 140 via microRNA-33 in inflammatory cytokine production
Q35773615Cholesterol, Inflammasomes, and Atherogenesis
Q30664287Cholesterol-induced membrane microvesicles as novel carriers of damage-associated molecular patterns: mechanisms of formation, action, and detoxification.
Q64071917Cholinergic Control of Inflammation, Metabolic Dysfunction, and Cognitive Impairment in Obesity-Associated Disorders: Mechanisms and Novel Therapeutic Opportunities
Q41965191Chronic ethanol feeding modulates inflammatory mediators, activation of nuclear factor-κB, and responsiveness to endotoxin in murine Kupffer cells and circulating leukocytes.
Q35575974Chronic inflammation and immunologic-based constraints in malignant disease
Q34155912Chronic low dose chlorine exposure aggravates allergic inflammation and airway hyperresponsiveness and activates inflammasome pathway
Q50073491Circulating Mitochondrial DNA at the Crossroads of Mitochondrial Dysfunction and Inflammation During Aging and Muscle Wasting Disorders.
Q37559660Clash of the Cytokine Titans: counter-regulation of interleukin-1 and type I interferon-mediated inflammatory responses
Q41462724Clinical chorioamnionitis at term I: microbiology of the amniotic cavity using cultivation and molecular techniques
Q40570787Clinical chorioamnionitis at term: the amniotic fluid fatty acyl lipidome.
Q57298518Clinical manifestations and basic mechanisms of myocardial ischemia/reperfusion injury
Q51149012Coevolution of the Toll-Like Receptor 4 Complex with Calgranulins and Lipopolysaccharide.
Q51545819Cold-inducible RNA-binding protein activates splenic T cells during sepsis in a TLR4-dependent manner.
Q33769787Cold-inducible RNA-binding protein mediates neuroinflammation in cerebral ischemia.
Q37383587Combinations of TLR ligands: a promising approach in cancer immunotherapy
Q42677054Common mechanisms in neurodegeneration and neuroinflammation: a BrainNet Europe gene expression microarray study
Q92381713Comparison of UV spectrometry and fluorometry-based methods for quantification of cell-free DNA in red cell components
Q92689501Compartmentalized profiling of amniotic fluid cytokines in women with preterm labor
Q38267715Complexity of danger: the diverse nature of damage-associated molecular patterns.
Q35979602Comprehensive Genome-Wide Transcriptomic Analysis of Immature Articular Cartilage following Ischemic Osteonecrosis of the Femoral Head in Piglets
Q90029901Computational Analysis Supports IL-17A as a Central Driver of Neutrophil Extracellular Trap-Mediated Injury in Liver Ischemia Reperfusion
Q42011891Conceptual aspects of self and nonself discrimination
Q89593442Concerned topics of epidural labor analgesia: labor elongation and maternal pyrexia: a systematic review
Q37990919Connecting type 1 and type 2 diabetes through innate immunity
Q38888995Connexins and their channels in inflammation
Q93064942Constitutive release of CPS1 in bile and its role as a protective cytokine during acute liver injury
Q28068037Contemporary views on inflammatory pain mechanisms: TRPing over innate and microglial pathways
Q48015285Contribution of alloantigens to hepatic ischemia/reperfusion injury: Roles of natural killer cells and innate immune recognition of nonself
Q49943339Control release of mitochondria-targeted antioxidant by injectable self-assembling peptide hydrogel ameliorated persistent mitochondrial dysfunction and inflammation after acute kidney injury
Q36357705Controlled cortical impact and craniotomy induce strikingly similar profiles of inflammatory gene expression, but with distinct kinetics
Q30641163Coronary endothelial dysfunction induced by nucleotide oligomerization domain-like receptor protein with pyrin domain containing 3 inflammasome activation during hypercholesterolemia: beyond inflammation
Q33613182Cot/tpl2 participates in the activation of macrophages by adiponectin.
Q89738918CpG-ODN-mediated TLR9 innate immune signalling and calcium dyshomeostasis converge on the NFκB inhibitory protein IκBβ to drive IL1α and IL1β expression
Q57216618Crepidiastrum denticulatum Extract Ameliorates Kidney Ischemia-Reperfusion Injury in Mice
Q36137849Critical role for mast cells in interleukin-1β-driven skin inflammation associated with an activating mutation in the nlrp3 protein
Q37462492Crosstalk between autophagy and inflammasomes
Q26766491Crosstalk between the heart and peripheral organs in heart failure
Q36925541Cryopreserved Mesenchymal Stromal Cells Maintain Potency in a Retinal Ischemia/Reperfusion Injury Model: Toward an off-the-shelf Therapy
Q39191687Current and Emerging Molecular Tests for Human Papillomavirus-Related Neoplasia in the Genomic Era.
Q26741264Current perspectives on the immunopathogenesis of systemic sclerosis
Q89304722Cyclic Stretching Exacerbates Tendinitis by Enhancing NLRP3 Inflammasome Activity via F-Actin Depolymerization
Q50525177Cytokine expression and barrier disruption in human corneal epithelial cells induced by alarmin released from necrotic cells.
Q34289365Cytosolic double-stranded RNA activates the NLRP3 inflammasome via MAVS-induced membrane permeabilization and K+ efflux
Q58774511Cytosolic nucleic acid sensors of the innate immune system promote liver regeneration after partial hepatectomy
Q39283173Cytotoxic lymphocytes and atherosclerosis: significance, mechanisms and therapeutic challenges
Q90318136DAMP-sensing receptors in sterile inflammation and inflammatory diseases
Q41215899DAMPs Synergize with Cytokines or Fibronectin Fragment on Inducing Chondrolysis but Lose Effect When Acting Alone
Q38154796DAMPs activating innate and adaptive immune responses in COPD.
Q26782785DAMPs from Cell Death to New Life
Q34549200DNA from dead cancer cells induces TLR9-mediated invasion and inflammation in living cancer cells
Q58102688DNA methylation profiling of acute chorioamnionitis-associated placentas and fetal membranes: insights into epigenetic variation in spontaneous preterm births
Q56897591DNA released from dying host cells mediates aluminum adjuvant activity
Q88945323DNase II activated by the mitochondrial apoptotic pathway regulates RIP1-dependent non-apoptotic hepatocyte death via the TLR9/IFN-β signaling pathway
Q38311981Damage response involves mechanisms conserved across plants, animals and fungi.
Q41117279Damage-Associated Molecular Pattern and Fetal Membrane Vascular Injury and Collagen Disorganization in Lipopolysaccharide-Induced Intra-amniotic Inflammation in Fetal Sheep
Q58784696Damage-Associated Molecular Patterns in Inflammatory Diseases
Q48269154Damage-associated molecular patterns and their role as initiators of inflammatory and auto-immune signals in systemic lupus erythematosus.
Q38088924Damage-associated molecular patterns control neutrophil recruitment.
Q28067434Damage-associated molecular patterns in cancer: a double-edged sword
Q58699651Damage-associated molecular patterns in inflammatory bowel disease: From biomarkers to therapeutic targets
Q42275953Damaged-self recognition as a general strategy for injury detection
Q34433042Damaged-self recognition in common bean (Phaseolus vulgaris) shows taxonomic specificity and triggers signaling via reactive oxygen species (ROS).
Q38895967Danger Signals and Inflammasomes: Stress-Evoked Sterile Inflammation in Mood Disorders.
Q50002873Danger Signals in the ICU.
Q34433019Danger signals - damaged-self recognition across the tree of life.
Q30279070Dealing with Danger in the CNS: The Response of the Immune System to Injury
Q26746687Decreased Cytotoxicity of Peripheral and Peritoneal Natural Killer Cell in Endometriosis
Q52321810Defective immuno- and thymoproteasome assembly causes severe immunodeficiency.
Q91782048Defining the Inflammatory Microenvironment in the Human Cochlea by Perilymph Analysis: Toward Liquid Biopsy of the Cochlea
Q54342984Demographically framing trade-offs between sensitivity and specificity illuminates selection on immunity.
Q37956517Dendritic cells and damage-associated molecular patterns: endogenous danger signals linking innate and adaptive immunity
Q36800214Dendritic cells limit fibroinflammatory injury in nonalcoholic steatohepatitis in mice.
Q90437444Design of anti-inflammatory heparan sulfate to protect against acetaminophen-induced acute liver failure
Q48249229Design, Synthesis and Evaluation of Oxazaborine Inhibitors of the NLRP3 Inflammasome
Q57230718Design, Synthesis, and Evaluation of Acrylamide Derivatives as Direct NLRP3 Inflammasome Inhibitors
Q42382307Detection of Pathogens in Blood for Diagnosis of Sepsis and Beyond
Q37596306Developmental onset of bilirubin-induced neurotoxicity involves Toll-like receptor 2-dependent signaling in humanized UDP-glucuronosyltransferase1 mice.
Q55107387Dexamethasone Protects Against Tourniquet-Induced Acute Ischemia-Reperfusion Injury in Mouse Hindlimb.
Q51290274Dexamethasone promotes long-term functional recovery of neuromuscular junction in a murine model of tourniquet-induced ischaemia-reperfusion.
Q29615636Diameter and rigidity of multiwalled carbon nanotubes are critical factors in mesothelial injury and carcinogenesis
Q90247704Differences in Diurnal Variation of Immune Responses in Microglia and Macrophages: Review and Perspectives
Q37685295Different impairment of immune and inflammation functions in short and long-term after ischemic stroke
Q53838293Differential mRNA expression of inflammasome genes NLRP1 and NLRP3 in abdominal aneurysmal and occlusive aortic disease.
Q39065203Disease tolerance and immunity in host protection against infection
Q37577170Disrupting the blood-brain barrier by focused ultrasound induces sterile inflammation.
Q34239000Dissociation of immune responses from pathogen colonization supports pattern recognition in C. elegans
Q87175775Distinct gene expression profiles provoked by polyacrylamide beads (Biogel) during chronic and acute inflammation in mice selected for maximal and minimal inflammatory responses
Q42355573Disulfide HMGB1 derived from platelets coordinates venous thrombosis in mice
Q53799532Divergent effects of Tlr9 deletion in experimental late venous thrombosis resolution and vein wall injury.
Q51553209Divergent impact of Toll-like receptor 2 deficiency on repair mechanisms in healthy muscle versus Duchenne muscular dystrophy.
Q24471760Do advanced glycation end-products play a role in malaria susceptibility?
Q58781307Drug Repurposing for Duchenne Muscular Dystrophy: The Monoamine Oxidase B Inhibitor Safinamide Ameliorates the Pathological Phenotype in Mice and in Myogenic Cultures From DMD Patients
Q34420360Early endothelial damage detected by circulating particles in baboons fed a diet high in simple carbohydrates in conjunction with saturated or unsaturated fat.
Q41271475Early onset of inflammation during ontogeny of bipolar disorder: the NLRP2 inflammasome gene distinctly differentiates between patients and healthy controls in the transition between iPS cell and neural stem cell stages
Q27027040Early pulmonary inflammation and lung damage in children with cystic fibrosis
Q36095573Effect of Long-Term Treatment with Fimasartan on Transient Focal Ischemia in Rat Brain
Q35038824Effect of beta-blocker therapy on the risk of infections and death after acute stroke--a historical cohort study
Q39172652Effect of sphingosine kinase modulators on interleukin-1β release, sphingosine 1-phosphate receptor 1 expression and experimental autoimmune encephalomyelitis
Q35846206Effective suppression of pro-inflammatory molecules by DHCA via IKK-NF-κB pathway, in vitro and in vivo.
Q92133211Effector-triggered immunity and pathogen sensing in metazoans
Q37322737Effects and mechanisms of chinese herbal medicine in ameliorating myocardial ischemia-reperfusion injury
Q35196706Effects of mesenchymal stem cell and fibroblast coating on immunogenic potential of prosthetic meshes in vitro
Q51235275Effects of pentachlorophenol and dichlorodiphenyltrichloroethane on secretion of interferon gamma (IFNγ) and tumor necrosis factor alpha (TNFα) from human immune cells.
Q70867808Efferocytosis perpetuates substance accumulation inside macrophage populations
Q28565392Eicosapentaenoic (EPA) and docosahexaenoic (DHA) acid differentially modulate rat neutrophil function in vitro
Q35318562Elevated levels of circulating IL-7 and IL-15 in patients with early stage prostate cancer.
Q38149864Emerging key roles for P2X receptors in the kidney
Q37916958Emerging mechanisms of neutrophil recruitment across endothelium
Q36713361Endogenous control of immunity against infection: tenascin-C regulates TLR4-mediated inflammation via microRNA-155
Q35541859Endogenous histones function as alarmins in sterile inflammatory liver injury through Toll-like receptor 9 in mice
Q38301981Endogenous intracellular cathelicidin enhances TLR9 activation in dendritic cells and macrophages.
Q58610958Endogenous muscle atrophy F-box is involved in the development of cardiac rupture after myocardial infarction
Q34507737Endometrial cells sense and react to tissue damage during infection of the bovine endometrium via interleukin 1
Q38267984Endothelial nanomedicine for the treatment of pulmonary disease.
Q90482128Endotracheal intubation results in acute tracheal damage induced by mtDNA/TLR9/NF-κB activity
Q41079090Endotracheal tube-induced sore throat pain and inflammation is coupled to the release of mitochondrial DNA
Q35043172Endovascular laser–tissue interactions and biological responses in relation to endovenous laser therapy
Q42918583Enhanced TLR-MYD88 signaling stimulates autoinflammation in SH3BP2 cherubism mice and defines the etiology of cherubism
Q37134816Enhanced biglycan gene expression in the adipose tissues of obese women and its association with obesity-related genes and metabolic parameters
Q37687369Enhancement of endothelial permeability by free fatty acid through lysosomal cathepsin B-mediated Nlrp3 inflammasome activation
Q41620454Epigenetic regulation in sepsis : current state of knowledge
Q61443116Essential roles of C-type lectin Mincle in induction of neuropathic pain in mice
Q33610059Ethanol, TLR3, and TLR4 Agonists Have Unique Innate Immune Responses in Neuron-Like SH-SY5Y and Microglia-Like BV2
Q37322066Evaluating Health Span in Preclinical Models of Aging and Disease: Guidelines, Challenges, and Opportunities for Geroscience
Q41679143Evaluation of a human in vitro hepatocyte-NPC co-culture model for the prediction of idiosyncratic drug-induced liver injury: A pilot study
Q55447079Evaluation of small intestinal damage in a rat model of 6 Minutes cardiac arrest.
Q36372845Evidence of perturbations of the cytokine network in preterm labor
Q27000764Expanding the clinical indications for α(1)-antitrypsin therapy
Q42501941Explants of intact endometrium to model bovine innate immunity and inflammation ex vivo
Q38209804Exploitation of the host ubiquitin system by human bacterial pathogens
Q35122783Exploring the neuroimmunopharmacology of opioids: an integrative review of mechanisms of central immune signaling and their implications for opioid analgesia
Q48371666Exposures to the environmental toxicants pentachlorophenol (PCP) and dichlorodiphenyltrichloroethane (DDT) modify secretion of interleukin 1-beta (IL-1β) from human immune cells
Q27304521Expression and function of S100A8/A9 (calprotectin) in human typhoid fever and the murine Salmonella model
Q57278869Expression of Complement Components and Regulators by Different Subtypes of Bone Marrow-Derived Macrophages
Q90251341Extracellular ADP augments microglial inflammasome and NF-κB activation via the P2Y12 receptor
Q34554838Extracellular ATP activates MAPK and ROS signaling during injury response in the fungus Trichoderma atroviride
Q37680164Extracellular ATP drives systemic inflammation, tissue damage and mortality.
Q37291605Extracellular ATP is involved in dsRNA-induced MUC5AC production via P2Y2R in human airway epithelium
Q36503546Extracellular Ca2+ is a danger signal activating the NLRP3 inflammasome through G protein-coupled calcium sensing receptors
Q28387701Extracellular HMGB1 regulates multi-walled carbon nanotube-induced inflammation in vivo
Q56358143Extracellular Vesicles: A Novel Target for Exercise-Mediated Reductions in Type 2 Diabetes and Cardiovascular Disease Risk
Q41033728Extracellular signal-regulated kinase 5 promotes acute cellular and systemic inflammation
Q35106699Extracellular vesicles modulate host-microbe responses by altering TLR2 activity and phagocytosis
Q34133549Facilitation of transcutaneous drug delivery and vaccine immunization by a safe laser technology
Q37733087Fat body, fat pad and adipose tissues in invertebrates and vertebrates: the nexus
Q82281354Fibrinogen as a damage-associated mitogenic signal for the renal fibroblast
Q38979803Fibronectin peptides as potential regulators of hepatic fibrosis through apoptosis of hepatic stellate cells.
Q46534884Fluorescence Imaging of Inflammation in Live Animals
Q39467732For Whom the Bell Tolls (and Nods): Spit-acular Saliva.
Q38833053Free fatty acid G-protein coupled receptor signaling in M1 skewed white adipose tissue macrophages.
Q58767611From fever to immunity: A new role for IGFBP-6?
Q38045235From sentinel cells to inflammatory culprits: cancer-associated fibroblasts in tumour-related inflammation
Q39269625Fueling Inflamm-Aging through Mitochondrial Dysfunction: Mechanisms and Molecular Targets.
Q104111366Functional crosstalk between myeloid Foxo1-β-catenin axis and Hedgehog/Gli1 signaling in oxidative stress response
Q40672617Functional diversity of microglia - how heterogeneous are they to begin with?
Q39253438Functional expression of the damage-associated molecular pattern receptor P2X7 on canine kidney epithelial cells
Q36499477Fungal antioxidant pathways promote survival against neutrophils during infection
Q37244310Galectin-3 causes enteric neuronal loss in mice after left sided permanent middle cerebral artery occlusion, a model of stroke
Q36262236Galectin-3 released in response to traumatic brain injury acts as an alarmin orchestrating brain immune response and promoting neurodegeneration.
Q35673725Gastrin-releasing peptide receptor (GRPR) mediates chemotaxis in neutrophils
Q28655057Genomic analysis and differential expression of HMG and S100A family in human arthritis: upregulated expression of chemokines, IL-8 and nitric oxide by HMGB1
Q41865453Genomic, Lipidomic and Metabolomic Analysis of Cyclooxygenase-null Cells: Eicosanoid Storm, Cross Talk, and Compensation by COX-1.
Q89920317Gintonin-Enriched Fraction Suppresses Heat Stress-Induced Inflammation Through LPA Receptor
Q39378704Glycyrrhizin and isoliquiritigenin suppress the LPS sensor toll-like receptor 4/MD-2 complex signaling in a different manner
Q26828771Growth and Development Symposium: Endotoxin, inflammation, and intestinal function in livestock
Q46750131Growth arrest and DNA damage-inducible protein (GADD34) enhanced liver inflammation and tumorigenesis in a diethylnitrosamine (DEN)-treated murine model
Q37444290Gut microbiota protects against gastrointestinal tumorigenesis caused by epithelial injury
Q38756562Gut mucosal DAMPs in IBD: from mechanisms to therapeutic implications
Q39333658Gut-liver axis, cirrhosis and portal hypertension: the chicken and the egg.
Q49571851HER2 overexpression triggers an IL-1α pro-inflammatory circuit to drive tumorigenesis and promote chemotherapy resistance
Q40494735HMGB1 Induces an Inflammatory Response in the Chorioamniotic Membranes That Is Partially Mediated by the Inflammasome
Q89710968Haematopoietic stem cell gene therapy with IL-1Ra rescues cognitive loss in mucopolysaccharidosis IIIA
Q27339208Haptoglobin enhances cardiac transplant rejection
Q89748459Harnessing cancer immunotherapy during the unexploited immediate perioperative period
Q50075685Harnessing the Power of Invariant Natural Killer T Cells in Cancer Immunotherapy
Q53680750Heat shock proteins are no DAMPs, rather 'DAMPERs'.
Q38040510Heat-shock proteins as endogenous ligands building a bridge between innate and adaptive immunity
Q37242901Helicobacter pylori Activates HMGB1 Expression and Recruits RAGE into Lipid Rafts to Promote Inflammation in Gastric Epithelial Cells
Q37504457Hepatitis C Virus Infection of Cultured Human Hepatoma Cells Causes Apoptosis and Pyroptosis in Both Infected and Bystander Cells
Q38190431Herbal medicines for ischemic stroke: combating inflammation as therapeutic targets
Q94522042Heterogeneity in the initiation, development and function of type 2 immunity
Q92048333High Mobility Group Box 1 and TLR4 Signaling Pathway in Gnotobiotic Piglets Colonized/Infected with L. amylovorus, L. mucosae, E. coli Nissle 1917 and S. Typhimurium
Q91012508High plasma level of S100A8/S100A9 and S100A12 at admission indicates a higher risk of death in septic shock patients
Q26864635Host innate immune responses to sepsis
Q33607035Host-derived, pore-forming toxin-like protein and trefoil factor complex protects the host against microbial infection.
Q33600149Human Bronchial Epithelial Cells Induce CD141/CD123/DC-SIGN/FLT3 Monocytes That Promote Allogeneic Th17 Differentiation.
Q57063918Human Mesenchymal Stem Cell Secretome from Bone Marrow or Adipose-Derived Tissue Sources for Treatment of Hypoxia-Induced Pulmonary Epithelial Injury
Q34526089Human NLRP3 inflammasome senses multiple types of bacterial RNAs
Q36513609Human endometrial regenerative cells attenuate renal ischemia reperfusion injury in mice
Q58129602Human mast cells promote colon cancer growth via bidirectional crosstalk: studies in 2D and 3D coculture models
Q37213913Human milk hyaluronan enhances innate defense of the intestinal epithelium
Q34548128Human trophoblast cells modulate endometrial cells nuclear factor κB response to flagellin in vitro.
Q42152837Human α1-Antitrypsin Binds to Heat-Shock Protein gp96 and Protects from Endogenous gp96-Mediated Injury In vivo
Q37602171Hyaluronan digestion controls DC migration from the skin.
Q34994216Hyaluronic acid oligosaccharides suppress TLR3-dependent cytokine expression in a TLR4-dependent manner
Q39947813Hyaluronidase decreases neutrophils infiltration to the inflammatory site
Q38022014Hydrogen peroxide in inflammation: messenger, guide, and assassin
Q49452793Hyperbaric oxygen protects against myocardial reperfusion injury via the inhibition of inflammation and the modulation of autophagy
Q95424041Hyperbaric oxygen therapy induces kidney protection in an ischemia/reperfusion model in rats
Q38428834Hyperuricemia-induced NLRP3 activation of macrophages contributes to the progression of diabetic nephropathy
Q42961537Hypoxia in plaque macrophages: a new danger signal for interleukin-1β activation?
Q38054037Hypoxia-induced inflammation in the lung: a potential therapeutic target in acute lung injury?
Q41903813IL-1 in Colon Inflammation, Colon Carcinogenesis and Invasiveness of Colon Cancer
Q37228002IL-17 promotes neutrophil entry into tumor-draining lymph nodes following induction of sterile inflammation
Q40555364IL-1α mediates cellular cross-talk in the airway epithelial mesenchymal trophic unit
Q39402943IL-33: biological properties, functions, and roles in airway disease
Q36111353Identification of the HSPB4/TLR2/NF-κB axis in macrophage as a therapeutic target for sterile inflammation of the cornea.
Q30440550Imaging mass spectrometry for assessing temporal proteomics: analysis of calprotectin in Acinetobacter baumannii pulmonary infection
Q49239605Imbalance between HDAC and HAT activities drives aberrant STAT1/MyD88 expression in macrophages from type 1 diabetic mice.
Q90732984Imbalance of Circulating Innate Lymphoid Cell Subpopulations in Patients With Septic Shock
Q26746467Immune Activation in the Liver by Nucleic Acids
Q64230743Immune Challenge Alters Reactivity of Hippocampal Noradrenergic System in Prenatally Stressed Aged Mice
Q26797993Immune interventions in stroke
Q27022067Immune mechanisms in cerebral ischemic tolerance
Q90712264Immune responses in cardiac repair and regeneration: a comparative point of view
Q52370950Immune responses in stroke: how the immune system contributes to damage and healing after stroke and how this knowledge could be translated to better cures?
Q94561560Immunobiology of Acute Chorioamnionitis
Q91446266Immunobiology of Inherited Muscular Dystrophies
Q39178654Immunogenic cell death: can it be exploited in PhotoDynamic Therapy for cancer?
Q90217778Immunoglobulin-driven Complement Activation Regulates Proinflammatory Remodeling in Pulmonary Hypertension
Q41136707Immunological and inflammatory mapping of vascularized composite allograft rejection processes in a rat model
Q52658037Immunology Guides Skeletal Muscle Regeneration.
Q49592831Immunotherapeutic Targeting of Tumor-Associated Blood Vessels
Q51811548Impact of Inflammation and Anti-inflammatory Modalities on Skeletal Muscle Healing: From Fundamental Research to the Clinic.
Q37950925Impaired clearance of apoptotic cells in germinal centers: implications for loss of B cell tolerance and induction of autoimmunity
Q58705617Impaired wound healing in type 1 diabetes is dependent on 5-lipoxygenase products
Q89549309Implications of immune-inflammatory responses in smooth muscle dysfunction and disease
Q45072338In Vivo Imaging of Microglial Calcium Signaling in Brain Inflammation and Injury
Q43087985In the eye of the storm: T cell behavior in the inflammatory microenvironment
Q53540745In vitro and in vivo anti-inflammatory activity of digested peptides derived from salmon myofibrillar protein conjugated with a small quantity of alginate oligosaccharide.
Q47237229In vivo evidence of inflammasome activation during spontaneous labor at term
Q92180592In vivo imaging of sterile microglial activation in rat brain after disrupting the blood-brain barrier with pulsed focused ultrasound: [18F]DPA-714 PET study
Q28393709In vivo molecular markers for pro-inflammatory cytokine M1 stage and resident microglia in trimethyltin-induced hippocampal injury
Q52660383In vivo monitoring of activated macrophages and neutrophils in response to ischemic osteonecrosis in a mouse model.
Q89514339In vivo monitoring of dynamic interaction between neutrophil and human umbilical cord blood-derived mesenchymal stem cell in mouse liver during sepsis
Q36288105Increasing the efficacy of tumor cell vaccines by enhancing cross priming
Q41286466Indigestible mitochondria cause heartburn
Q39424757Indirubin-3-monoxime exhibits anti-inflammatory properties by down-regulating NF-κB and JNK signaling pathways in lipopolysaccharide-treated RAW264.7 cells
Q35065280Induction of inflammasome-dependent pyroptosis by carbon black nanoparticles
Q28070341Infiltrating monocytes in liver injury and repair
Q28074446Inflamm-Aging of Hematopoiesis, Hematopoietic Stem Cells, and the Bone Marrow Microenvironment
Q38521274Inflammasome activation and function in liver disease
Q33660585Inflammasome activation by cystine crystals: implications for the pathogenesis of cystinosis
Q36969137Inflammasome and toll-like receptor signaling in human monocytes after successful cardiopulmonary resuscitation
Q57492010Inflammasome: A Double-Edged Sword in Liver Diseases
Q36234946Inflammasomes in intestinal inflammation and cancer
Q57179097Inflammasomes in livestock and wildlife: Insights into the intersection of pathogens and natural host species
Q26740458Inflammasomes in the Pathophysiology of Kidney Diseases
Q27001186Inflammasomes: mechanism of action, role in disease, and therapeutics
Q38664204Inflammation - Cause or Consequence of Heart Failure or Both?
Q90682365Inflammation and Bone Repair: From Particle Disease to Tissue Regeneration
Q47309460Inflammation and Its Consequences After Surgical Versus Transcatheter Aortic Valve Replacement.
Q30278352Inflammation in AKI: Current Understanding, Key Questions, and Knowledge Gaps
Q38692603Inflammation in Epileptic Encephalopathies.
Q58735426Inflammation in Right Ventricular Failure: Does It Matter?
Q35691449Inflammation, endoplasmic reticulum stress, autophagy, and the monocyte chemoattractant protein-1/CCR2 pathway
Q37474699Inflammatory Disequilibrium in Stroke
Q90481598Inflammatory extracellular vesicles prompt heart dysfunction via TRL4-dependent NF-κB activation
Q57488901Inflammatory projections after focal brain injury trigger neuronal network disruption: An F-DPA714 PET study in mice
Q39648492Inflammatory responses increase secretion of MD-1 protein
Q27692695Inflection points in sepsis biology: from local defense to systemic organ injury
Q43478399Influence of endotoxin-mediated retinal inflammation on phenotype of diabetic retinopathy in Ins2 Akita mice.
Q89598619Influences of Nanoparticles Characteristics on the Cellular Responses: The Example of Iron Oxide and Macrophages
Q35565652Inhibition of 4-1BBL-regulated TLR response in macrophages ameliorates endotoxin-induced sepsis in mice
Q36719155Inhibition of IL-1R1/MyD88 signalling promotes mesenchymal stem cell-driven tissue regeneration
Q37729147Inhibition of NLRP3 Inflammasome Pathway by Butyrate Improves Corneal Wound Healing in Corneal Alkali Burn.
Q46608425Inhibition of ceramide de novo synthesis as a postischemic strategy to reduce myocardial reperfusion injury.
Q37716823Inhibition of the phosphoinositide 3-kinase pathway decreases innate resistance to lipopolysaccharide toxicity in TLR4 deficient mice
Q92451281Inhibitory effect of nintedanib on VEGF secretion in retinal pigment epithelial cells induced by exposure to a necrotic cell lysate
Q98226408Innate Immune Receptors, Key Actors in Cardiovascular Diseases
Q38662811Innate Immune Response in Kidney Ischemia/Reperfusion Injury: Potential Target for Therapy.
Q38221985Innate and adaptive immune responses subsequent to ischemia-reperfusion injury in the kidney
Q35205885Innate and adaptive immune responses to cell death.
Q38808100Innate immune mechanisms in transplant allograft vasculopathy
Q38163168Innate immune mechanisms in vitiligo: danger from within
Q38771560Innate immune memory: Implications for host responses to damage-associated molecular patterns
Q42410751Innate immune regulation by toll-like receptors in the brain
Q36857029Innate immune responses in house dust mite allergy
Q42856952Innate immunity and coagulation.
Q36420171Innate immunity and organ transplantation: focus on lung transplantation
Q39232871Innate immunity in Sjögren's syndrome.
Q92494838Innate immunity in allergy
Q37897264Innate immunity in the human endometrium and ovary
Q48292170Innate immunity's path to the Nobel Prize 2011 and beyond
Q34364828Innate inflammation induced by the 8-oxoguanine DNA glycosylase-1-KRAS-NF-κB pathway
Q38877941Innate sensing of oxidation-specific epitopes in health and disease
Q90049905Innovative Drugs to Target Renal Inflammation in Sepsis: Alkaline Phosphatase
Q36394688Instigation of endothelial Nlrp3 inflammasome by adipokine visfatin promotes inter-endothelial junction disruption: role of HMGB1.
Q90072341Inter-Organelle Membrane Contact Sites and Mitochondrial Quality Control during Aging: A Geroscience View
Q47271148Interaction between environment, nutrient-derived metabolites and immunity: A possible role in malaria susceptibility/resistance in Fulani and Dogon of Mali
Q35014476Interaction of Pattern Recognition Receptors with Mycobacterium Tuberculosis
Q47653353Interleukin 1 gene polymorphism and susceptibility to disease
Q38533781Interleukin-1 as a pharmacological target in acute brain injury
Q35931135Interleukin-1 in lipopolysaccharide induced chorioamnionitis in the fetal sheep
Q41614701Interleukin-1 receptor antagonist is beneficial after subarachnoid haemorrhage in rat by blocking haem-driven inflammatory pathology
Q38439111Interleukin-1α and brain inflammation
Q38706264Interleukin-1β (IL-1β) transcriptionally activates hepcidin by inducing CCAAT enhancer-binding protein δ (C/EBPδ) expression in hepatocytes
Q47096936Interplay between trauma and Pseudomonas entomophila infection in flies: a central role of the JNK pathway and of CrebA.
Q37269788Intra-Amniotic Administration of HMGB1 Induces Spontaneous Preterm Labor and Birth
Q34421715Intra-amniotic LPS modulates expression of antimicrobial peptides in the fetal sheep lung.
Q28591187Intracellular interleukin-1 receptor 2 binding prevents cleavage and activity of interleukin-1α, controlling necrosis-induced sterile inflammation
Q37925070Intracellular sensing of microbes and danger signals by the inflammasomes
Q37452198Intracranial transplantation of human adipose-derived stem cells promotes the expression of neurotrophic factors and nerve repair in rats of cerebral ischemia-reperfusion injury
Q33781043Intranasal delivery of cell-penetrating anti-NF-κB peptides (Tat-NBD) alleviates infection-sensitized hypoxic-ischemic brain injury
Q90638466Intratumoral delivery of RIG-I agonist SLR14 induces robust antitumor responses
Q49592640Intravital Microscopic Evaluation of the Effects of a CXCR2 Antagonist in a Model of Liver Ischemia Reperfusion Injury in Mice
Q28081530Intravital imaging - dynamic insights into natural killer T cell biology
Q35684611Intravitreal TSG-6 suppresses laser-induced choroidal neovascularization by inhibiting CCR2+ monocyte recruitment
Q30700375Invariant NKT Cell Activation Induces Late Preterm Birth That Is Attenuated by Rosiglitazone
Q47168463Involvement of Innate Immune System in Late Stages of Inherited Photoreceptor Degeneration
Q44035557Involvement of damage-associated molecular patterns in tumor response to photodynamic therapy: surface expression of calreticulin and high-mobility group box-1 release
Q37027584Irradiation enhances susceptibility of tumor cells to the antitumor effects of TNF-α activated adipose derived mesenchymal stem cells in breast cancer model
Q37455225Ischemia and reperfusion--from mechanism to translation
Q33653045Ischemia-reperfusion injury in stroke
Q34532361Ischemia/reperfusion Injury and its Consequences on Immunity and Inflammation
Q41831209Isolation of cortical microglia with preserved immunophenotype and functionality from murine neonates
Q91173354Keep calm: the intestinal barrier at the interface of peace and war
Q36092488Keratin and S100 calcium-binding proteins are major constituents of the bovine teat canal lining.
Q90632963Kidney Perfusion as an Organ Quality Assessment Tool-Are We Counting Our Chickens Before They Have Hatched?
Q90474075Kidney allograft fibrosis: what we learned from latest translational research studies
Q28544395LPS nephropathy in mice is ameliorated by IL-2 independently of regulatory T cells activity
Q46256576Lactoferrin in a Context of Inflammation-Induced Pathology
Q98779115Lamivudine Inhibits Alu RNA-induced Retinal Pigment Epithelium Degeneration via Anti-inflammatory and Anti-senescence Activities
Q91776030Landscape of innate immune system transcriptome and acute T cell-mediated rejection of human kidney allografts
Q90317183Leucine-rich repeats and calponin homology containing 4 (Lrch4) regulates the innate immune response
Q35167112Leukotriene B4-mediated sterile inflammation promotes susceptibility to sepsis in a mouse model of type 1 diabetes
Q64234898Leukotriene Involvement in the Insulin Receptor Pathway and Macrophage Profiles in Muscles from Type 1 Diabetic Mice
Q37641651Ligand dependent restoration of human TLR3 signaling and death in p53 mutant cells.
Q21131203Lights, camera, and action: vertebrate skin sets the stage for immune cell interaction with arthropod-vectored pathogens
Q35581200Lipopolysaccharide Induces Alveolar Macrophage Necrosis via CD14 and the P2X7 Receptor Leading to Interleukin-1α Release
Q42752441Lipopolysaccharide inhibits transforming growth factor-beta1-stimulated Smad6 expression by inducing phosphorylation of the linker region of Smad3 through a TLR4-IRAK1-ERK1/2 pathway
Q47721012Lithium ameliorates sleep deprivation-induced mania-like behavior, hypothalamic-pituitary-adrenal (HPA) axis alterations, oxidative stress and elevations of cytokine concentrations in the brain and serum of mice.
Q56951980Liver repercussions of defective gut surveillance
Q88911059Liver sinusoidal endothelial cells - gatekeepers of hepatic immunity
Q38951232Local TNFR1 Signaling Licenses Murine Neutrophils for Increased TLR-Dependent Cytokine and Eicosanoid Production
Q37935450Localization of sclerotic-type chronic graft-vs-host disease to sites of skin injury: potential insight into the mechanism of isomorphic and isotopic responses
Q34311706Longistatin in tick saliva blocks advanced glycation end-product receptor activation
Q89597890Low Molecular Weight Hyaluronan Induces an Inflammatory Response in Ovarian Stromal Cells and Impairs Gamete Development In Vitro
Q38699191Low-dose radiation accelerates aging of the T-cell receptor repertoire in CBA/Ca mice.
Q41497232Lower frequency of TLR9 variant associated with protection from breast cancer among African Americans
Q35702619Lung Ischemia-Reperfusion is a Sterile Inflammatory Process Influenced by Commensal Microbiota in Mice
Q38050047Lung ischemia reperfusion injury: a bench-to-bedside review
Q39732801Lysophospholipid Receptors, as Novel Conditional Danger Receptors and Homeostatic Receptors Modulate Inflammation-Novel Paradigm and Therapeutic Potential
Q51065015MAFB prevents excess inflammation after ischemic stroke by accelerating clearance of damage signals through MSR1.
Q99635811MCC950, a selective NLPR3 inflammasome inhibitor, improves neurologic function and survival after cardiac arrest and resuscitation
Q57116018MRI and histological evaluation of pulsed focused ultrasound and microbubbles treatment effects in the brain
Q33693237Macrophage CGI-58 deficiency activates ROS-inflammasome pathway to promote insulin resistance in mice
Q28068907Macrophage in chronic kidney disease
Q34240471Macrophage phenotype as a predictor of constructive remodeling following the implantation of biologically derived surgical mesh materials.
Q40201540Macrophage-derived IL-1α promotes sterile inflammation in a mouse model of acetaminophen hepatotoxicity.
Q36060408Macrophage-mediated inflammation in metabolic disease
Q89701276Macrophages employ quorum licensing to regulate collective activation
Q38453872Macrophages in kidney injury, inflammation, and fibrosis
Q38194688Macrophages in solid organ transplantation
Q88392842Macrophages play an essential role in trauma-induced sterile inflammation and tissue repair
Q38846881Malondialdehyde Epitopes as Targets of Immunity and the Implications for Atherosclerosis
Q24613714Many stimuli pull the necrotic trigger, an overview
Q52576158Maresins: Specialized Proresolving Lipid Mediators and Their Potential Role in Inflammatory-Related Diseases.
Q33700247Mechanisms and consequences of injury and repair in older organ transplants
Q89338772Mechanisms of Hemolysis During Sepsis
Q91707988Mechanisms of Immune Tolerance in Liver Transplantation-Crosstalk Between Alloreactive T Cells and Liver Cells With Therapeutic Prospects
Q26998870Mechanisms of chemotherapy-induced behavioral toxicities
Q26992155Mechanisms of epithelial wound detection
Q30277205Mechanisms of lung ischemia-reperfusion injury
Q38054535Mechanisms of mesenchymal stromal cell immunomodulation
Q46290278Mechanisms of the Innate Defense Regulator Peptide-1002 Anti-Inflammatory Activity in a Sterile Inflammation Mouse Model
Q27025291Medical therapies with adult stem/progenitor cells (MSCs): a backward journey from dramatic results in vivo to the cellular and molecular explanations
Q104111207Menstrual blood-derived stromal cells modulate functional properties of mouse and human macrophages
Q36775656Mesenchymal stem cell transplantation inhibited high salt-induced activation of the NLRP3 inflammasome in the renal medulla in Dahl S rats
Q35665181Mesenchymal stem/stromal cells (MSCs): role as guardians of inflammation
Q39048543Mesenchymal stem/stromal cells inhibit the NLRP3 inflammasome by decreasing mitochondrial reactive oxygen species
Q36070565Mesenchymal stromal cells in renal ischemia/reperfusion injury.
Q97644269Metabolic Modulation of Macrophage Function Post Myocardial Infarction
Q28080815Metabolic reprogramming in macrophages and dendritic cells in innate immunity
Q39725717Metal nanoparticles in the presence of lipopolysaccharides trigger the onset of metal allergy in mice
Q42004335Methylene blue inhibits NLRP3, NLRC4, AIM2, and non-canonical inflammasome activation
Q92419079MiRNA-199a-5p Protects Against Cerebral Ischemic Injury by Down-Regulating DDR1 in Rats
Q47781954MicroRNA-1906, a Novel Regulator of Toll-Like Receptor 4, Ameliorates Ischemic Injury after Experimental Stroke in Mice.
Q35066721Microbiota and nonalcoholic steatohepatitis
Q34647371Microbiota and the gut-liver axis: bacterial translocation, inflammation and infection in cirrhosis
Q38016812Microglia and neurodegeneration: the role of systemic inflammation.
Q28396123Microglial Heparan Sulfate Proteoglycans Facilitate the Cluster-of-Differentiation 14 (CD14)/Toll-like Receptor 4 (TLR4)-Dependent Inflammatory Response
Q36547001Microglial M1/M2 polarization and metabolic states
Q36640417Microglial activation and antioxidant responses induced by the Parkinson's disease protein α-synuclein
Q37949246Microglial cell origin and phenotypes in health and disease
Q38072224Microparticles and their impact on intestinal immunity
Q35851522Mitochondria and cell signalling
Q39334539Mitochondria in Structural and Functional Cardiac Remodeling
Q34799187Mitochondria in innate immune responses
Q54261138Mitochondrial DNA as an inflammatory mediator in cardiovascular diseases.
Q38754086Mitochondrial DNA in Sepsis
Q38759328Mitochondrial DNA sensing by STING signaling participates in inflammation, cancer and beyond
Q55025737Mitochondrial Damage-Associated Molecular Patterns: From Inflammatory Signaling to Human Diseases.
Q89172402Mitochondrial Dysfunction in Stroke: Implications of Stem Cell Therapy
Q30234722Mitochondrial Function in Allergic Disease
Q36631427Mitochondrial Targeted Antioxidant in Cerebral Ischemia
Q99726354Mitochondrial donation in translational medicine; from imagination to reality
Q38925765Mitochondrial lysates induce inflammation and Alzheimer's disease-relevant changes in microglial and neuronal cells
Q35205924Mitoxosome: a mitochondrial platform for cross-talk between cellular stress and antiviral signaling.
Q52647873Mobilization of hematopoietic stem cells as a result of innate immunity-mediated sterile inflammation in the bone marrow microenvironment-the involvement of extracellular nucleotides and purinergic signaling.
Q38169796Modifiable risk factors in periodontitis: at the intersection of aging and disease
Q64106871Modulating autophagy in mesenchymal stem cells effectively protects against hypoxia- or ischemia-induced injury
Q38462525Modulating the Immune Response Towards a Neuroregenerative Peri-injury Milieu After Cerebral Hemorrhage
Q26739428Modulation of Alloimmunity by Heat Shock Proteins
Q28083042Modulation of the host innate immune and inflammatory response by translocated bacterial proteins
Q35679745Molecular Interactions between NR4A Orphan Nuclear Receptors and NF-κB Are Required for Appropriate Inflammatory Responses and Immune Cell Homeostasis
Q91942485Molecular and Functional Analysis of Pore-Forming Toxin Monalysin From Entomopathogenic Bacterium Pseudomonas entomophila
Q92759525Molecular pathobiology of scleritis and its therapeutic implications
Q34005059Molecular pathogenesis of post-transplant acute kidney injury: assessment of whole-genome mRNA and miRNA profiles
Q34959012Monocytes in sterile inflammation: recruitment and functional consequences
Q36666383Monosodium urate activates Src/Pyk2/PI3 kinase and cathepsin dependent unconventional protein secretion from human primary macrophages
Q37303479Monosodium urate crystal-induced pro-interleukin-1β production is post-transcriptionally regulated via the p38 signaling pathway in human monocytes
Q55022654Morinda citrifolia L. Leaf Extract Protects against Cerebral Ischemia and Osteoporosis in an In Vivo Experimental Model of Menopause.
Q59173736Mouse models of preterm birth: suggested assessment and reporting guidelines†
Q92965151Moving beyond the glial scar for spinal cord repair
Q34270155Multifarious roles of sialic acids in immunity
Q58700279MyD88 signaling causes autoimmune sialadenitis through formation of high endothelial venules and upregulation of LTβ receptor-mediated signaling
Q36301100Mycobacterial infection induces a specific human innate immune response
Q34468940Myeloid-related protein-14 contributes to protective immunity in gram-negative pneumonia derived sepsis
Q61053503Myosin II Synergizes with F-Actin to Promote DNGR-1-Dependent Cross-Presentation of Dead Cell-Associated Antigens
Q49180290N-acetylcysteine exposure is associated with improved survival in anti-nuclear antibody seropositive patients with usual interstitial pneumonia.
Q54241856NADPH oxidase activation regulates apoptotic neutrophil clearance by murine macrophages.
Q36382191NADPH oxidase controls neutrophilic response to sterile inflammation in mice by regulating the IL-1α/G-CSF axis.
Q91713477NAMPT and NAPRT: Two Metabolic Enzymes With Key Roles in Inflammation
Q37675611NETosis in Alzheimer's Disease.
Q39142554NF-κB as a Therapeutic Target in Inflammatory-Associated Bone Diseases
Q49894086NHERF1 Between Promises and Hopes: Overview on Cancer and Prospective Openings
Q26766141NKT cell subsets as key participants in liver physiology and pathology
Q104459169NKT cells promote both type 1 and type 2 inflammatory responses in a mouse model of liver fibrosis
Q58745474NLRP3 Inflammasome and IL-33: Novel Players in Sterile Liver Inflammation
Q64122385NLRP3 inflammasome couples purinergic signaling with activation of the complement cascade for the optimal release of cells from bone marrow
Q48401313NLRP3 is Required for Complement-Mediated Caspase-1 and IL-1beta Activation in ICH.
Q35575228NLRP3 mediates NF-κB activation and cytokine induction in microbially induced and sterile inflammation
Q36867370NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22.
Q42048184NLRP3-Inflammasome Activating DAMPs Stimulate an Inflammatory Response in Glia in the Absence of Priming Which Contributes to Brain Inflammation after Injury
Q89529534NOD-like Receptors in the Eye: Uncovering Its Role in Diabetic Retinopathy
Q46840121Nanosilica-induced placental inflammation and pregnancy complications: Different roles of the inflammasome components NLRP3 and ASC.
Q36033943Natural Killer Cells-Produced IFN-γ Improves Bone Marrow-Derived Hepatocytes Regeneration in Murine Liver Failure Model
Q35829866Necroptosis suppresses inflammation via termination of TNF- or LPS-induced cytokine and chemokine production
Q35862108Necrosis-Induced Sterile Inflammation Mediated by Interleukin-1α in Retinal Pigment Epithelial Cells
Q41183770Necrosis-induced TLR3 Activation Promotes TLR2 Expression in Gingival Cells.
Q36067773Necrotic cell-derived high mobility group box 1 attracts antigen-presenting cells but inhibits hepatocyte growth factor-mediated tropism of mesenchymal stem cells for apoptotic cell death.
Q57285359Neuroimmunomodulation in Major Depressive Disorder: Focus on Caspase 1, Inducible Nitric Oxide Synthase, and Interferon-Gamma
Q38834682Neuroprotection in acute stroke: targeting excitotoxicity, oxidative and nitrosative stress, and inflammation
Q33587711Neuroprotective pentapeptide CN-105 is associated with reduced sterile inflammation and improved functional outcomes in a traumatic brain injury murine model
Q64118264Neutrophil Effector Functions Are Not Impaired in Duffy Antigen Receptor for Chemokines (DARC)-Null Black South Africans
Q37323729Neutrophil Extracellular Traps Form a Barrier between Necrotic and Viable Areas in Acute Abdominal Inflammation
Q48507345Neutrophil extracellular traps contribute to the pathogenesis of acid-aspiration-induced ALI/ARDS.
Q40387374Neutrophil extracellular traps in acute chorioamnionitis: A mechanism of host defense
Q36369202Neutrophil extracellular traps in the host defense against sepsis induced by Burkholderia pseudomallei (melioidosis)
Q50072392Neutrophil peptidyl arginine deiminase-4 has a pivotal role in ischemia/reperfusion-induced acute kidney injury
Q29616689Neutrophil recruitment and function in health and inflammation
Q82872710Neutrophil recruitment on the big screen
Q41577006Neutrophil recruitment to the brain in mouse and human ischemic stroke.
Q37959327Neutrophils and intravascular immunity in the liver during infection and sterile inflammation
Q38057854Neutrophils come of age in chronic inflammation
Q64075095Neutrophils in Leprosy
Q49567474Neutrophils in tissue injury and repair
Q99595579Neutrophils promote clearance of nuclear debris following acid-induced lung injury
Q49571206Neutrophils take a round-trip
Q50047875Neutrophils: a cornerstone of liver ischemia and reperfusion injury
Q55493201New application of anti-TLR monoclonal antibodies: detection, inhibition and protection.
Q36492375New approaches to the study of sepsis
Q38694219New molecular insights in diabetic nephropathy
Q36434255Next-Generation mRNA Sequencing Reveals Pyroptosis-Induced CD4+ T Cell Death in Early Simian Immunodeficiency Virus-Infected Lymphoid Tissues
Q41064009Nlrp6 promotes recovery after peripheral nerve injury independently of inflammasomes
Q33856333Nonconvulsive seizures in subarachnoid hemorrhage link inflammation and outcome
Q46423222Noninvasive Transcutaneous Vagus Nerve Stimulation Decreases Whole Blood Culture-Derived Cytokines and Chemokines: A Randomized, Blinded, Healthy Control Pilot Trial
Q36079268Noninvasive molecular imaging of neuroinflammation
Q92616710Normal Saline solutions cause endothelial dysfunction through loss of membrane integrity, ATP release, and inflammatory responses mediated by P2X7R/p38 MAPK/MK2 signaling pathways
Q61942332Novel evidence that extracellular nucleotides and purinergic signaling induce innate immunity-mediated mobilization of hematopoietic stem/progenitor cells
Q37893442Novel inflammatory mechanisms of accelerated atherosclerosis in kidney disease
Q38021271Nucleic acid sensing at the interface between innate and adaptive immunity in vaccination
Q27011448Nucleic acids in circulation: are they harmful to the host?
Q37655598Obesity paradox, obesity orthodox, and the metabolic syndrome: An approach to unity
Q64936281Olive Leaf Extract (OleaVita) Suppresses Inflammatory Cytokine Production and NLRP3 Inflammasomes in Human Placenta.
Q92405052Osteoimmunology of Oral and Maxillofacial Diseases: Translational Applications Based on Biological Mechanisms
Q27024707Oxidative Stress and Lung Ischemia-Reperfusion Injury
Q60047016Oxidative Stress and Neonatal Respiratory Extracorporeal Membrane Oxygenation
Q97884465Oxidative Stress and Neuroinflammation Potentiate Each Other to Promote Progression of Dopamine Neurodegeneration
Q26852796Oxidative Stress and the Use of Antioxidants in Stroke
Q55400548Oxidative stress, NOx/l-arginine ratio and glutathione/glutathione S-transferase ratio as predictors of 'sterile inflammation' in patients with alcoholic cirrhosis and hepatorenal syndrome type II.
Q36426181Ozone-induced lung injury and sterile inflammation. Role of toll-like receptor 4.
Q43741223P2X7 receptor is required for neutrophil accumulation in a mouse model of irritant contact dermatitis.
Q27013790PAMPs and DAMPs as triggers for DIC
Q36997603PET imaging of inflammation biomarkers
Q33825045PKCδ-IRAK1 axis regulates oxidized LDL-induced IL-1β production in monocytes.
Q54244545PLAP-1/Asporin Regulates TLR2- and TLR4-induced Inflammatory Responses.
Q35849962Pancreatic secretory trypsin inhibitor I reduces the severity of chronic pancreatitis in mice overexpressing interleukin-1β in the pancreas.
Q35203274Pancreatic stone protein predicts postoperative infection in cardiac surgery patients irrespective of cardiopulmonary bypass or surgical technique
Q62066924Pathogen- or damage-associated molecular patterns during nonalcoholic fatty liver disease development
Q26801594Pathophysiology and Immune Dysfunction in Endometriosis
Q57452740Pathophysiology of Sickle Cell Disease
Q39165266Pathophysiology of heart failure and frailty: a common inflammatory origin?
Q39359763Patients with HBV-related acute-on-chronic liver failure have increased concentrations of extracellular histones aggravating cellular damage and systemic inflammation
Q33358901Pattern recognition receptors and DNA repair: starting to put a jigsaw puzzle together
Q39143987Pediatric Perioperative Stress Responses and Anesthesia
Q37992548Peeking into the secret life of neutrophils.
Q51441692Peri-conceptual cytokines--setting the trajectory for embryo implantation, pregnancy and beyond.
Q39262680Perinatal Brain Injury As a Consequence of Preterm Birth and Intrauterine Inflammation: Designing Targeted Stem Cell Therapies.
Q41836365Perioperative Dynamics of TLR2, TLR4, and TREM-1 Expression in Monocyte Subpopulations in the Setting of On-Pump Coronary Artery Bypass Surgery
Q37593569Perioperative organ injury
Q30583655Perivascular macrophages mediate neutrophil recruitment during bacterial skin infection
Q48502190Peroxiredoxin family proteins are key initiators of post-ischemic inflammation in the brain
Q38287139Peroxiredoxin sets the brain on fire after stroke
Q47775496Persistent Increase in Microglial RAGE Contributes to Chronic Stress-Induced Priming of Depressive-like Behavior.
Q38963920Persistent change in cardiac fibroblast physiology after transient ACE inhibition
Q38657314Persistent phenotypic shift in cardiac fibroblasts: impact of transient renin angiotensin system inhibition
Q38113059Phagocyte dysfunction, tissue aging and degeneration
Q93052161Phagocytosis of Necrotic Debris at Sites of Injury and Inflammation
Q36953689Pharmacological inhibition of MyD88 homodimerization counteracts renal ischemia reperfusion-induced progressive renal injury in vivo and in vitro
Q90567984Plasma Adenylate Levels are Elevated in Cardiopulmonary Arrest Patients and May Predict Mortality
Q57803934Plasma high mobility group box 1 protein reflects fibrosis in pediatric nonalcoholic fatty liver disease
Q36736945Plasminogen activator inhibitor-1 mitigates brain injury in a rat model of infection-sensitized neonatal hypoxia-ischemia.
Q38147906Platelet-rich plasma for managing pain and inflammation in osteoarthritis
Q90263726Pleiotropic Roles of P2X7 in the Central Nervous System
Q26852816Polyionic vaccine adjuvants: another look at aluminum salts and polyelectrolytes
Q43062179Postoperative Ileus: Pathophysiology, Current Therapeutic Approaches
Q37588473Potential specific immunological indicators for stroke associated infection are partly modulated by sympathetic pathway activation
Q91868562Potentiating vascular-targeted photodynamic therapy through CSF-1R modulation of myeloid cells in a preclinical model of prostate cancer
Q40959934Preimplantation Kidney Biopsies of Extended Criteria Donors Have a Heavier Inflammatory Burden Than Kidneys From Standard Criteria Donors
Q48915949Prenatal bystander stress alters brain, behavior, and the epigenome of developing rat offspring
Q54204527Preparation of Murine Submandibular Salivary Gland for Upright Intravital Microscopy.
Q92877303Preservation Solutions for Kidney Transplantation: History, Advances and Mechanisms
Q51737047Preterm Life in Sterile Conditions: A Study on Preterm, Germ-Free Piglets.
Q34315899Prevalence and clinical significance of sterile intra-amniotic inflammation in patients with preterm labor and intact membranes
Q59807348Preventing Peritoneal Dialysis-Associated Fibrosis by Therapeutic Blunting of Peritoneal Toll-Like Receptor Activity
Q40529040Production, purification and crystallization of a trans-sialidase from Trypanosoma vivax
Q55413894Profibrogenic effect of high-mobility group box protein-1 in human dermal fibroblasts and its excess in keloid tissues.
Q43156007Prolonged apoptotic cell accumulation in germinal centers of Mer-deficient mice causes elevated B cell and CD4+ Th cell responses leading to autoantibody production
Q60960053Protective Effect of Anthocyanin on Neurovascular Unit in Cerebral Ischemia/Reperfusion Injury in Rats
Q89287836Protective Effects of Curcumin Against Ischemia-Reperfusion Injury in the Nervous System
Q29620351Protective and pathogenic functions of macrophage subsets
Q46691819Protective effect of Malva sylvestris L. extract in ischemia-reperfusion induced acute kidney and remote liver injury.
Q35988805Proteolytic Cleavage of AMPKα and Intracellular MMP9 Expression Are Both Required for TLR4-Mediated mTORC1 Activation and HIF-1α Expression in Leukocytes.
Q28536582Proteome mapping of adult zebrafish marrow neutrophils reveals partial cross species conservation to human peripheral neutrophils
Q55221792Proteomic Identification of Heat Shock-Induced Danger Signals in a Melanoma Cell Lysate Used in Dendritic Cell-Based Cancer Immunotherapy.
Q35645169Proteomic insight into the molecular function of the vitreous
Q90403945Protocol for TRAUMADORNASE: a prospective, randomized, multicentre, double-blinded, placebo-controlled clinical trial of aerosolized dornase alfa to reduce the incidence of moderate-to-severe hypoxaemia in ventilated trauma patients
Q35217392Pulmonary and systemic inflammatory responses to intra-amniotic IL-1α in fetal sheep
Q52323412Pulmonary immunity and extracellular matrix interactions.
Q49817801Pulmonary toxicity and global gene expression changes in response to sub-chronic inhalation exposure to crystalline silica in rats
Q37984097Purine nucleosides: endogenous neuroprotectants in hypoxic brain.
Q34152663Purine-metabolizing ectoenzymes control IL-8 production in human colon HT-29 cells.
Q35543272Purinergic regulation of high-glucose-induced caspase-1 activation in the rat retinal Müller cell line rMC-1.
Q34035530Purinergic signalling during sterile liver injury
Q37726294Putative role of protein kinase C in neurotoxic inflammation mediated by extracellular heat shock protein 70 after ischemia-reperfusion.
Q35571709Quantitative Trait Loci and Candidate Genes for Neutrophil Recruitment in Sterile Inflammation Mapped in AXB-BXA Recombinant Inbred Mice
Q41876141Quantitative in vitro assay to measure neutrophil adhesion to activated primary human microvascular endothelial cells under static conditions
Q27025295RAGE: a new frontier in chronic airways disease
Q36931209RIP1-driven autoinflammation targets IL-1α independently of inflammasomes and RIP3.
Q26853214ROCKs as immunomodulators of stroke
Q29615229ROS function in redox signaling and oxidative stress
Q41092652Rapamycin regulates macrophage activation by inhibiting NLRP3 inflammasome-p38 MAPK-NFκB pathways in autophagy- and p62-dependent manners
Q42009505Rapid Activation of Transforming Growth Factor β-Activated Kinase 1 in Chondrocytes by Phosphorylation and K63 -Linked Polyubiquitination Upon Injury to Animal Articular Cartilage
Q24603469Rapid evolution of binding specificities and expression patterns of inhibitory CD33-related Siglecs in primates
Q91650570Reactivation of NR4A1 Restrains Chondrocyte Inflammation and Ameliorates Osteoarthritis in Rats
Q35915428Reactive oxygen species and nitric oxide in cutaneous leishmaniasis.
Q88590167Real-time dynamics of neutrophil clustering in response to phototoxicity-induced cell death and tissue damage in mouse ear dermis
Q92940669Recent Advances in Models, Mechanisms, Biomarkers, and Interventions in Cisplatin-Induced Acute Kidney Injury
Q37121662Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.
Q37737094Receptor Mincle promotes skin allergies and is capable of recognizing cholesterol sulfate.
Q36488241Receptor interacting protein-2 contributes to host defense against Anaplasma phagocytophilum infection
Q27010116Recognition of human oncogenic viruses by host pattern-recognition receptors
Q34963571Reconstituted high-density lipoprotein modulates activation of human leukocytes
Q64087511Redefining Chronic Inflammation in Aging and Age-Related Diseases: Proposal of the Senoinflammation Concept
Q38244572Redox regulation of inflammation: old elements, a new story
Q38551809Redox stress unbalances the inflammatory cytokine network: role in autoinflammatory patients and healthy subjects
Q39256123Redox-dependent regulation of hepatocyte absent in melanoma 2 inflammasome activation in sterile liver injury in mice
Q39742832Reducing hypoxia and inflammation during invasive pulmonary aspergillosis by targeting the Interleukin-1 receptor
Q61809864Regeneration-associated cell transplantation contributes to tissue recovery in mice with acute ischemic stroke
Q35892487Regenerative medicine as applied to general surgery
Q36764867Regnase-1 in microglia negatively regulates high mobility group box 1-mediated inflammation and neuronal injury
Q26781203Regulation of Bim in Health and Disease
Q26800988Regulation of Dendritic Cell Function in Inflammation
Q38044319Regulation of microglia activation and deactivation by nuclear receptors
Q38065649Regulation of wound healing and organ fibrosis by toll-like receptors.
Q26745537Regulatory T-Cell-Mediated Suppression of Conventional T-Cells and Dendritic Cells by Different cAMP Intracellular Pathways
Q35208204Renal intercalated cells sense and mediate inflammation via the P2Y14 receptor
Q61807034Resistance and Tolerance to Cryptococcal Infection: An Intricate Balance That Controls the Development of Disease
Q38039092Resolution of inflammation in obesity-induced liver disease.
Q57136936Resveratrol Prevents Warm Ischemia-Reperfusion Injury in Liver Grafts From Non-Heart-Beating Donor Rats
Q35805767Resveratrol pretreatment protects rat hearts from ischemia/reperfusion injury partly via a NALP3 inflammasome pathway
Q33470645Role of Ambient Gas Composition on Cold Physical Plasma-Elicited Cell Signaling in Keratinocytes
Q90245610Role of Damage Associated Molecular Pattern Molecules (DAMPs) in Aneurysmal Subarachnoid Hemorrhage (aSAH)
Q37542677Role of Mitochondria-Associated Endoplasmic Reticulum Membrane in Inflammation-Mediated Metabolic Diseases
Q35686207Role of NLRP3 Inflammasomes for Rhabdomyolysis-induced Acute Kidney Injury
Q47682969Role of NLRP3 inflammasome in the pathogenesis of cardiovascular diseases
Q27012868Role of Nlrp6 and Nlrp12 in the maintenance of intestinal homeostasis
Q38793108Role of TLRs and DAMPs in allograft inflammation and transplant outcomes.
Q42144361Role of heat shock protein 70 in innate alloimmunity
Q38256054Role of inflammasome activation in the pathophysiology of vascular diseases of the neurovascular unit.
Q38544560Role of innate immune system in systemic sclerosis
Q37962297Role of innate immunity and the microbiota in liver fibrosis: crosstalk between the liver and gut.
Q27023760Role of microglia in CNS inflammation
Q38009737Role of phospholipase A2s and lipid mediators in secondary damage after spinal cord injury.
Q90248296Role of the NLRP3 Inflammasome in Preeclampsia
Q35495434Role of the NLRP3 inflammasome in the transient release of IL-1β induced by monosodium urate crystals in human fibroblast-like synoviocytes
Q91276841Route of immunization defines multiple mechanisms of vaccine-mediated protection against SIV
Q58713351S100A12 facilitates osteoclast differentiation from human monocytes
Q64105054SBT2171 Induces A20 Expression via Toll-Like Receptor 2 Signaling and Inhibits the Lipopolysaccharide-Induced Activation of Nuclear Factor-kappa B and Mitogen-Activated Protein Kinases in Peritoneal Macrophages
Q55448893SNPs in inflammatory genes CCL11, CCL4 and MEFV in a fibromyalgia family study.
Q64054763SOCS and Herpesviruses, With Emphasis on Cytomegalovirus Retinitis
Q91890877STING signaling and host defense against microbial infection
Q37502349STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors.
Q36540171STING-cytosolic DNA sensing: the backbone for an effective tumor radiation therapy
Q39389951STING-mediated DNA sensing in cancer immunotherapy
Q38731119STK11/LKB1 Deficiency Promotes Neutrophil Recruitment and Proinflammatory Cytokine Production to Suppress T-cell Activity in the Lung Tumor Microenvironment.
Q36080628Salivary pellets induce a pro-inflammatory response involving the TLR4-NF-kB pathway in gingival fibroblasts
Q35483838Sclerotic-type chronic GVHD of the skin: clinical risk factors, laboratory markers, and burden of disease
Q34998188Self and non-self discrimination of intracellular membranes by the innate immune system
Q56889933Self-associated molecular patterns mediate cancer immune evasion by engaging Siglecs on T cells
Q52371276Senescence and cell death in chronic liver injury: roles and mechanisms underlying hepatocarcinogenesis.
Q36253171Sensing and reacting to microbes through the inflammasomes
Q39326078Sepsis: Current Definition, Pathophysiology, Diagnosis, and Management
Q46324575Serum Iron Protects from Renal Postischemic Injury.
Q64065096Serum concentrations of CCL20/MIP-3alpha in women with endometriosis
Q34765284Shigella IpaH0722 E3 ubiquitin ligase effector targets TRAF2 to inhibit PKC-NF-κB activity in invaded epithelial cells.
Q57204151Signal inhibitory receptor on leukocytes-1 (SIRL-1) negatively regulates the oxidative burst in human phagocytes
Q28253084Signaling by the matrix proteoglycan decorin controls inflammation and cancer through PDCD4 and MicroRNA-21
Q41009240Silence of NLRP3 suppresses atherosclerosis and stabilizes plaques in apolipoprotein E-deficient mice
Q36269639Silymarin suppresses basal and stimulus-induced activation, exhaustion, differentiation, and inflammatory markers in primary human immune cells
Q35147045Since there are PAMPs and DAMPs, there must be SAMPs? Glycan “self-associated molecular patterns” dampen innate immunity, but pathogens can mimic them
Q26866098Skewed Helper T-Cell Responses to IL-12 Family Cytokines Produced by Antigen-Presenting Cells and the Genetic Background in Behcet's Disease
Q36012754Small leucine-rich proteoglycans orchestrate receptor crosstalk during inflammation.
Q99417713Small-Molecule Inhibitor of 8-Oxoguanine DNA Glycosylase 1 Regulates Inflammatory Responses during Pseudomonas aeruginosa Infection
Q39029151Sparstolonin B attenuates hypoxia-reoxygenation-induced cardiomyocyte inflammation
Q89932299Spatiotemporal Proteomics Reveals the Molecular Consequences of Hormone Treatment in a Mouse Model of Lower Urinary Tract Dysfunction
Q36379060Sphingosine regulates the NLRP3-inflammasome and IL-1β release from macrophages.
Q39549057Stanniocalcin-1 attenuates ischemic cardiac injury and response of differentiating monocytes/macrophages to inflammatory stimuli
Q41107325Stat-6 signaling pathway and not Interleukin-1 mediates multi-walled carbon nanotube-induced lung fibrosis in mice: insights from an adverse outcome pathway framework
Q52589498Stem cell-derived mitochondria transplantation: a novel strategy and the challenges for the treatment of tissue injury.
Q55069783Sterile Inflammation of Brain, due to Activation of Innate Immunity, as a Culprit in Psychiatric Disorders.
Q90721410Sterile Inflammation, Potential Target in Aneurysmal Subarachnoid Hemorrhage
Q36144350Sterile inflammation - do innate lymphoid cell subsets play a role?
Q36873728Sterile inflammation in acetaminophen-induced liver injury is mediated by Cot/tpl2.
Q35549073Sterile inflammation in the spleen during atherosclerosis provides oxidation-specific epitopes that induce a protective B-cell response
Q27023854Sterile inflammatory response in acute pancreatitis
Q26748401Sterile post-traumatic immunosuppression
Q89995936Stimuli-Responsive Delivery of Growth Factors for Tissue Engineering
Q28071417Stress-induced neuroinflammatory priming: A liability factor in the etiology of psychiatric disorders
Q37867782Stroke and the immune system: from pathophysiology to new therapeutic strategies
Q34714413Structural mechanisms in NLR inflammasome signaling.
Q93173251Sulforaphane reduces intracellular survival of Staphylococcus aureus in macrophages through inhibition of JNK and p38 MAPK‑induced inflammation
Q90344384Suppressive effects of S100A8 and S100A9 on neutrophil apoptosis by cytokine release of human bronchial epithelial cells in asthma
Q47917345Surfactant inhibits ATP-induced release of interleukin-1β via nicotinic acetylcholine receptors
Q40053779Susceptibility of M. tuberculosis-infected host cells to phospho-MLKL driven necroptosis is dependent on cell type and presence of TNFα.
Q30356149Syncytiotrophoblast extracellular vesicles - Circulating biopsies reflecting placental health.
Q36964798Synergistic Effect of Compounds from a Chinese Herb: Compatibility and Dose Optimization of Compounds from N-Butanol Extract of Ipomoea stolonifera
Q89302959Synthesis of interleukin 1 beta and interleukin 6 in human lymphocytes is stimulated by tributyltin
Q40116872Systematic Investigation of Multi-TLR Sensing Identifies Regulators of Sustained Gene Activation in Macrophages
Q39401125Systemic CD14 inhibition attenuates organ inflammation in porcine Escherichia coli sepsis
Q39172554Systemic effects of ionizing radiation at the proteome and metabolome levels in the blood of cancer patients treated with radiotherapy: the influence of inflammation and radiation toxicity
Q35212454Systemic inflammation impairs respiratory chemoreflexes and plasticity
Q51320785Systemic inflammation in acute intermittent porphyria: a case-control study.
Q21032488Systems immunology of human malaria
Q50957253T inflammatory memory CD8 T cells participate to antiviral response and generate secondary memory cells with an advantage in XCL1 production.
Q37745189TAK1 regulates resident macrophages by protecting lysosomal integrity
Q40066649TCR-pMHC encounter differentially regulates transcriptomes of(-) tissue-resident CD8 T cells.
Q90214018TGF-β/SMAD4 mediated UCP2 downregulation contributes to Aspergillus protease-induced inflammation in primary bronchial epithelial cells
Q38132733TLR2 & Co: a critical analysis of the complex interactions between TLR2 and coreceptors
Q35091594TLR2, TLR4 and CD14 recognize venom-associated molecular patterns from Tityus serrulatus to induce macrophage-derived inflammatory mediators
Q34601443TSG-6 as a biomarker to predict efficacy of human mesenchymal stem/progenitor cells (hMSCs) in modulating sterile inflammation in vivo.
Q35855616TXNIP links innate host defense mechanisms to oxidative stress and inflammation in retinal Muller glia under chronic hyperglycemia: implications for diabetic retinopathy
Q41928977Targeting Innate Immunity for Type 1 Diabetes Prevention
Q39044981Targeting cancer-related inflammation in the era of immunotherapy
Q38071254Targeting the "cytokine storm" for therapeutic benefit
Q42361197Targeting the NLRP3 inflammasome to reduce diet-induced metabolic abnormalities in mice
Q36041765Temporal and spatial expression of high-mobility group box 1 in surgically injured rat vocal folds
Q89812439Tendon and ligament mechanical loading in the pathogenesis of inflammatory arthritis
Q37230888The Cag pathogenicity island and interaction between TLR2/NOD2 and NLRP3 regulate IL-1β production in Helicobacter pylori infected dendritic cells
Q64953901The Complement Cascade as a Mediator of Human Malignant Hematopoietic Cell Trafficking.
Q64241117The Different Effects of IFN-β and IFN-γ on the Tumor-Suppressive Activity of Human Amniotic Fluid-Derived Mesenchymal Stem Cells
Q54260140The Dual Role of Neutrophils in HIV Infection.
Q55313072The Emerging Link Between the Complement Cascade and Purinergic Signaling in Stress Hematopoiesis.
Q42152131The Emerging Role of TLR and Innate Immunity in Cardiovascular Disease
Q35974974The Fifth Domain of Beta 2 Glycoprotein I Protects from Natural IgM Mediated Cardiac Ischaemia Reperfusion Injury
Q35056726The HMGB1/RAGE axis triggers neutrophil-mediated injury amplification following necrosis
Q57492001The IL-20 Cytokine Family in Rheumatoid Arthritis and Spondyloarthritis
Q34237954The Immune Response to Acute Focal Cerebral Ischemia and Associated Post-stroke Immunodepression: A Focused Review
Q58122075The Impact of Invariant NKT Cells in Sterile Inflammation: The Possible Contribution of the Alarmin/Cytokine IL-33
Q92538561The Increase in IL-1β in the Early Stage of Heatstroke Might Be Caused by Splenic Lymphocyte Pyroptosis Induced by mtROS-Mediated Activation of the NLRP3 Inflammasome
Q36971550The NLRP3 Inflammasome as a novel player of the intercellular crosstalk in metabolic disorders
Q54331250The NLRP3/ASC/Caspase-1 axis regulates IL-1β processing in neutrophils.
Q64911231The Nlrp3 Inflammasome Orchestrates Mobilization of Bone Marrow-Residing Stem Cells into Peripheral Blood.
Q92094167The Nlrp3 inflammasome as a "rising star" in studies of normal and malignant hematopoiesis
Q49276928The Pollutant Organotins Leads to Respiratory Disease by Inflammation: A Mini-Review.
Q53699942The Potential for Connexin Hemichannels to Drive Breast Cancer Progression through Regulation of the Inflammatory Response.
Q55501304The Regulation of Inflammation by Innate and Adaptive Lymphocytes.
Q48244517The Role of Danger Signals in the Pathogenesis and Perpetuation of Critical Illness
Q40101162The Role of Interferons in Inflammation and Inflammasome Activation
Q47130227The Role of Sphingosine-1-Phosphate and Ceramide-1-Phosphate in Inflammation and Cancer.
Q28396823The Roles of Mitochondrial Damage-Associated Molecular Patterns in Diseases
Q34238722The S100B protein in biological fluids: more than a lifelong biomarker of brain distress
Q92670282The Sleep-Immune Crosstalk in Health and Disease
Q37683183The Small Tellurium Compound AS101 Ameliorates Rat Crescentic Glomerulonephritis: Association with Inhibition of Macrophage Caspase-1 Activity via Very Late Antigen-4 Inactivation
Q33737254The Soft- and Hard-Heartedness of Cardiac Fibroblasts: Mechanotransduction Signaling Pathways in Fibrosis of the Heart
Q40823404The TAK1→IKKβ→TPL2→MKK1/MKK2 Signaling Cascade Regulates IL-33 Expression in Cystic Fibrosis Airway Epithelial Cells Following Infection by Pseudomonas aeruginosa.
Q59967267The TIR-domain-containing adapter inducing interferon-β-dependent signaling cascade plays a crucial role in ischemia-reperfusion-induced retinal injury, whereas the contribution of the myeloid differentiation primary response 88-dependent signaling
Q38117377The TLR family protein RP105/MD-1 complex: A new player in obesity and adipose tissue inflammation
Q57080590The TWIK2 Potassium Efflux Channel in Macrophages Mediates NLRP3 Inflammasome-Induced Inflammation
Q34752364The Toll/NF-κB signaling pathway is required for epidermal wound repair in Drosophila.
Q28385117The alarmin IL-1α is a master cytokine in acute lung inflammation induced by silica micro- and nanoparticles
Q39014623The anti-inflammatory effect of combined complement and CD14 inhibition is preserved during escalating bacterial load
Q39144663The biochemical alterations underlying post-burn hypermetabolism
Q35201430The biological basis of injury and neuroprotection in the fetal and neonatal brain
Q38805996The complex biology and contribution of Staphylococcus aureus in atopic dermatitis, current and future therapies.
Q21131221The danger theory: 20 years later
Q55046775The diversity of myeloid immune cells shaping wound repair and fibrosis in the lung.
Q36884123The effect of PEGylation on the stimulation of IL-1β by gold (Au) nanoshell/silica core nanoparticles
Q43072756The extracellular release of DNA and HMGB1 from Jurkat T cells during in vitro necrotic cell death
Q35909787The heat shock response restricts virus infection in Drosophila
Q35519094The high-mobility group box-1 nuclear factor mediates retinal injury after ischemia reperfusion.
Q55709181The immune system as a victim and aggressor in chronic obstructive pulmonary disease.
Q38016069The immunology of acute stroke
Q92893644The immunostimulatory effects and pro-apoptotic activity of rhCNB against Lewis lung cancer is mediated by Toll-like receptor 4
Q38074651The immunosuppressive activity of heat shock protein 70.
Q28389385The innate immune response to products of phospholipid peroxidation
Q38102657The long pentraxin PTX3: a candidate anti-inflammatory mediator in cardiac surgery.
Q37727892The mouse cyclophosphamide model of bladder pain syndrome: tissue characterization, immune profiling, and relationship to metabotropic glutamate receptors.
Q36968316The multicomponent medication lymphomyosot improves the outcome of experimental lymphedema
Q37953775The neutrophil in vascular inflammation
Q36887359The p38α MAPK regulates microglial responsiveness to diffuse traumatic brain injury.
Q41966425The radioprotective 105/MD-1 complex contributes to diet-induced obesity and adipose tissue inflammation.
Q38867621The regulation of inflammation by oxidized phospholipids
Q38063499The role of TLR and chemokine in wear particle-induced aseptic loosening
Q38074434The role of gut-liver axis in the pathogenesis of liver cirrhosis and portal hypertension
Q33941549The role of high mobility group box 1 in innate immunity
Q38142061The role of inflammation and interleukin-1 in acute cerebrovascular disease
Q36331560The role of inflammation in perinatal brain injury
Q38320224The role of innate immunity in osteoarthritis: when our first line of defense goes on the offensive
Q57120700The role of neutrophils in triptolide-induced liver injury
Q35373060The sterile inflammation in the exacerbation of HBV-associated liver injury
Q36233768The transcription of the alarmin cytokine interleukin-1 alpha is controlled by hypoxia inducible factors 1 and 2 alpha in hypoxic cells
Q27010599The translocation of nuclear molecules during inflammation and cell death
Q33847366The vagus nerve and the inflammatory reflex--linking immunity and metabolism
Q41634439The xanthine oxidase inhibitor Febuxostat reduces tissue uric acid content and inhibits injury-induced inflammation in the liver and lung
Q54988971Therapeutic Potential of Annexin A1 in Ischemia Reperfusion Injury.
Q41170285Therapeutic Potential of Intravenous Immunoglobulin in Acute Brain Injury
Q28676201Therapeutic targeting of NOD1 receptors
Q36960966Therapeutic targets for cholestatic liver injury
Q96303536Ticagrelor inhibits the NLRP3 inflammasome to protect against inflammatory disease independent of the P2Y12 signaling pathway
Q38951112Time course of cardiac inflammation during nitric oxide synthase inhibition in SHR: impact of prior transient ACE inhibition
Q64984430Tirofiban, a Glycoprotein IIb/IIIa Antagonist, Has a Protective Effect on Decompression Sickness in Rats: Is the Crosstalk Between Platelet and Leukocytes Essential?
Q88693530Tissue Damage Signaling Is a Prerequisite for Protective Neutrophil Recruitment to Microbial Infection in Zebrafish
Q92239205Tissue Dependent Role of PTX3 During Ischemia-Reperfusion Injury
Q38227799Tissue regeneration in stroke: cellular and trophic mechanisms
Q27302768Tolerance and Cross-Tolerance following Toll-Like Receptor (TLR)-4 and -9 Activation Are Mediated by IRAK-M and Modulated by IL-7 in Murine Splenocytes
Q57784611Tolerance and Innate Immunity Shape the Development of Postpartum Uterine Disease and the Impact of Endometritis in Dairy Cattle
Q38333830Toll gates: An emerging therapeutic target
Q54752771Toll-Like Receptor 2 Signaling and Current Approaches for Therapeutic Modulation in Synucleinopathies.
Q64058653Toll-Like Receptor 9 Plays a Pivotal Role in Angiotensin II-Induced Atherosclerosis
Q59130037Toll-Like Receptor Stimulation by MicroRNAs in Acute Graft-vs.-Host Disease
Q89831517Toll-Like Receptor-4 Antagonist (+)-Naltrexone Protects Against Carbamyl-Platelet Activating Factor (Cpaf)-Induced Preterm Labor in Mice
Q40608326Toll-Like Receptors 2 and 4 Are Potential Therapeutic Targets in Peritoneal Dialysis-Associated Fibrosis
Q41128526Toll-like Receptor 2: A Novel Therapeutic Target for Ischemic White Matter Injury and Oligodendrocyte Death.
Q35234073Toll-like receptor 4 ablation in mdx mice reveals innate immunity as a therapeutic target in Duchenne muscular dystrophy
Q34994429Toll-like receptor 4-mediated nuclear factor kappa B activation is essential for sensing exogenous oxidants to propagate and maintain oxidative/nitrosative cellular stress
Q34261565Toll-like receptor 9-mediated protection of enterovirus 71 infection in mice is due to the release of danger-associated molecular patterns
Q38103581Toll-like receptor agonists: current status and future perspective on their utility as adjuvants in improving anticancer vaccination strategies
Q43075865Toll-like receptors and their role in persistent pain
Q33697107Toll-like receptors and their soluble forms differ in the knee and thumb basal osteoarthritic joints.
Q38196396Topographical changes in extracellular matrix: Activation of TLR4 signaling and solid tumor progression
Q37637116Tracing the dynamics of gene transcripts after organismal death.
Q91303775Trained Innate Immunity and Its Implications for Mucosal Immunity and Inflammation
Q30572360Transcranial amelioration of inflammation and cell death after brain injury.
Q34984258Transcription of Tnfaip3 is regulated by NF-κB and p38 via C/EBPβ in activated macrophages
Q92700295Transcriptome Modifications in Porcine Adipocytes via Toll-Like Receptors Activation
Q45710915Transcriptome analysis of neutrophils after endurance exercise reveals novel signaling mechanisms in the immune response to physiological stress.
Q23919916Transcriptomics analysis of lungs and peripheral blood of silica-exposed rats
Q57176523Transflammation: How Innate Immune Activation and Free Radicals Drive Nuclear Reprogramming
Q46306206Transflammation: Innate immune signaling in nuclear reprogramming
Q89667122Transitions in metabolic and immune systems from pre-menopause to post-menopause: implications for age-associated neurodegenerative diseases
Q38791503Translocation of Endogenous Danger Signal HMGB1 From Nucleus to Membrane Microvesicles in Macrophages
Q42031076Transplantable subcutaneous hepatoma 22a affects functional activity of resident tissue macrophages in periphery
Q27334687Treadmill exercise induces neutrophil recruitment into muscle tissue in a reactive oxygen species-dependent manner. An intravital microscopy study
Q36194849Trial Watch: Experimental Toll-like receptor agonists for cancer therapy
Q42969291Trial Watch: Toll-like receptor agonists for cancer therapy
Q57394699Trial Watch: Toll-like receptor agonists in cancer immunotherapy
Q33878578Trial Watch: Toll-like receptor agonists in oncological indications
Q36373370Trial watch: FDA-approved Toll-like receptor agonists for cancer therapy
Q35582631Tributyltin alters secretion of interleukin 1 beta from human immune cells
Q45072779Trimethylamine-N-Oxide Instigates NLRP3 Inflammasome Activation and Endothelial Dysfunction
Q28085631Tumor cell survival pathways activated by photodynamic therapy: a molecular basis for pharmacological inhibition strategies
Q91272383Tumor necrosis factor induces rapid down-regulation of TXNIP in human T cells
Q36492390Tumour inflammasome-derived IL-1β recruits neutrophils and improves local recurrence-free survival in EBV-induced nasopharyngeal carcinoma
Q37031838Two independent pathways of regulated necrosis mediate ischemia-reperfusion injury
Q37501797UVB-induced skin inflammation and cutaneous tissue injury is dependent on the MHC class I-like protein, CD1d
Q30826655Underlying chronic inflammation alters the profile and mechanisms of acute neutrophil recruitment
Q89967655Understanding Inflammatory Responses in the Manifestation of Prothrombotic Phenotypes
Q38209325Understanding MHC class I presentation of viral antigens by human dendritic cells as a basis for rational design of therapeutic vaccines
Q87361939Understanding why clinicians should care about danger-associated molecular patterns
Q41943672Unique Versus Redundant Functions of IL-1α and IL-1β in the Tumor Microenvironment
Q28078744Update on Inflammatory Biomarkers and Treatments in Ischemic Stroke
Q38541350Update on ischemia-reperfusion injury in kidney transplantation: Pathogenesis and treatment
Q42737499Upregulation of IFN-Inducible and Damage-Response Pathways in Chronic Graft-versus-Host Disease.
Q36071959Urate crystals induce NLRP3 inflammasome-dependent IL-1β secretion and proliferation in isolated primary human T-cells.
Q37524355Uric Acid Crystals Induce Placental Inflammation and Alter Trophoblast Function via an IL-1-Dependent Pathway: Implications for Fetal Growth Restriction.
Q36829387Uric acid as a danger signal in gout and its comorbidities
Q42082561Uric acid induces caspase-1 activation, IL-1β secretion and P2X7 receptor dependent proliferation in primary human lymphocytes
Q34326473Uric acid induces renal inflammation via activating tubular NF-κB signaling pathway
Q35034053Urinary metabolite profiling offers potential for differentiation of liver-kidney yin deficiency and dampness-heat internal smoldering syndromes in posthepatitis B cirrhosis patients
Q38259561Use and isolation of urinary exosomes as biomarkers for diabetic nephropathy
Q34714365Venous and arterial disease in inflammatory bowel disease
Q26825031Virus-like particles as antigenic nanomaterials for inducing protective immune responses in the lung
Q41990643Visualizing the function and fate of neutrophils in sterile injury and repair
Q39419931Vitiligo: Focus on Clinical Aspects, Immunopathogenesis, and Therapy
Q37217051Weakened cholinergic blockade of inflammation associates with diabetes-related depression.
Q37381509Why is neuroimmunopharmacology crucial for the future of addiction research?
Q36552242XH-14, a novel danshen methoxybenzo[b]furan derivative, exhibits anti-inflammatory properties in lipopolysaccharide-treated RAW 264.7 cells
Q36641946Xylitol, an anticaries agent, exhibits potent inhibition of inflammatory responses in human THP-1-derived macrophages infected with Porphyromonas gingivalis
Q42872095Zebrafish as animal model for aquaculture nutrition research
Q51557570Zinc Carnosine Inhibits Lipopolysaccharide-Induced Inflammatory Mediators by Suppressing NF-κb Activation in Raw 264.7 Macrophages, Independent of the MAPKs Signaling Pathway.
Q38697554Zinc L-carnosine suppresses inflammatory responses in lipopolysaccharide-induced RAW 264.7 murine macrophages cell line via activation of Nrf2/HO-1 signaling pathway.
Q40139387Zinc depletion regulates the processing and secretion of IL-1β.
Q42783371α-Synuclein Alters Toll-Like Receptor Expression
Q37360437γ-Glutamyltranspeptidase is an endogenous activator of Toll-like receptor 4-mediated osteoclastogenesis
Q38270170γδ T cells as early sensors of tissue damage and mediators of secondary neurodegeneration

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